Cyclosporine (cyclosporin A) is a naturally occurring compound produced by soil fungi.

It has a much more specific effect on immune function than do either corticosteroids or
cytotoxic agents. While the exact mechanism of action of cyclosporine remains controversial, the primary effects appear to be related to inhibition of T-cell activation and
recruitment, most likely through its suppressive effect on interleukin-1 function and indirect inhibition of interlukin-2(IL-2) production, which are necessary for activation of T-
lymphocytes.