Studies are currently being done with other types of cyclosporine, for example, cyclosporin G, which appears to be less nephrotoxic than is cyclosporin A. At present,
cyclosporine should be considered in cases of severe bilateral posterior uveitis that is poorly responsive to more conventional therapy. While probably not carcinogenic, in
contrast to the cytotoxic agents, the teratogenic effects of cyclosporine are unknown. Its use in pregnancy should thus be avoided unless absolutely necessary, and then should
be used only after consultation with the patient's obstetrician or internist, or both.