Matric No. Programme Group No. se Name of Lecturer larga apallleMagalll nM zicallell INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA STAN DME a Salo CENTRE FOR FOUNDATION STUDIES MID-SEMESTER EXAMINATION, SEMESTER |, 2011/2012 DEPARTMENT OF SCIENCES PROGRAMMES SUBJECT: BIOLOGY | CODE: SHF1415 DATE! DAY: 26/07/2014 (TUESDAY) TIME: 2.30PM-4.00PM DO NOT OPEN UNTIL YOU ARE TOLD TO DO SO 4 area 00 For Exarivers | Sere se only use only won sips ssonan | tiara a Head number Total Obtained elmer Ceram utnm woe | FREED B2 B3 sasyronw or cusarna on arreuer ro |—23 = seokeinecarnc on rraner"® [ch ‘This question booklet consists of 19 printed TOTAL roe NAME: VENUE: MATRIC NO: DATE/DAY: PROGRAMME: ‘SIGNATURE: SEMESTER: SUBJECT CODE: NAME OF LECTURER: SECTION NO:MID-SEMESTER/SI/11-12/SHF1415 SECTION A [20 marks] Answer all questions on the MCQ answer sheet provided. “He set on the (earth), mountains standing firm, high above it, and bestowed blessings on the earth, and measure therein all things to give them nourishment in due proportion, in four Days, in accordance with (the needs of) those who seek (Sustenance).” [Translation of the Noble Quran, 41:90] Which of the following best explains the verse above? I Formation of solar system Formation of universe III Formation of earth IV __ Formation of life A land IT B Tand Ill c Itandiv D IandIv Listed below are the proposed events which might have occurred during the formation of early earth. Formation of primordial soup Less meteorite collision and solar radiation Volcanic eruption Formation of primitive atmosphere AWK “What is the correct order of the events? A 13933452 B eee c 2937491 D 3343192 2 DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUM3 MID-SEMESTER/SI/11-12/SHF1415 “The fact that life evolved out of nearly nothing, some 10 billion years after the universe evolved out of literally nothing, is a fact so staggering that I would be mad to attempt words to do it justice.’ [Quoted from Richard Dawkin] The above quote from Richard Dawkin refers to which of the following? Special Creation Big Bang Theory Panspermia Theory ‘Spontaneous Origin oomp Which of the following is a result of the high surface tension of water? Water flows upward from the roots to the leaves in plants A water strider can walk across the water surface of a pond Lakes do not freeze solid in winter, despite low temperature Evaporation of sweat from the skin helps to keep people from overheating onmD> Which properties of water help it to moderate changes in temperature? A Cohesion and adhesion B Polarity and hydrogen bonding C Solvent and high specific heat capacity D High specific heat capacity and high heat of vaporization What process breaks down carbohydrates into their monomers? A Reduction B Hydrolysis € — Oxidization D Condensation DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUMMID-SEMESTER/SI/11-12/SHF1415 Which of the following are roles of carbohydrates in living things? goup 2 As the main source of energy As structural component in arthropods As raw material for manufacture of vitamin D As raw material for synthesis of other monomers 1, Hand Ir I, and IV II, IIL and IV I, IL, Il and IV Which of the following is not a similarity between the structure of glycogen and amylopectin? com> Both form a-helix chains Both are formed from a-glucose units Both are made up of short non-branching chains Both contain a-1,4 glycosidic and a-1,6 glycosidic linkages 4 DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUMMID-SEMESTER/SI/11-12/SHF1415 Figure 1 shows two types of protein, E and F. Molecule E Modified from ; http://hu Figure 1 Molecule F man/images/topic75.. Which of the following are true about the differences between molecules E and F? Molecule E Molecule F I Soluble Insoluble 11 [Fibrous protein Globular protein II Very stable structure Unstable structure Iv__ | Function: Component of structure and support Function: Catalyzes metabolic reactions A I, I and It B I,IandIv cI, IWland Iv D II, Il and IV DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUM10 a1 am 13 MID-SEMESTER/SI/11-12/SHF1415 Which of the following are present in prokaryotic cells? o> z DNA Ribosome Chloroplast Mitochondria Land ID B Land Iv II and IT D Ill and IV Which structures are usually present in animal cells but not in plant cells? I IL Il Iv A c Microtubules Lysosome Centrioles Plastids Tand Iv B ILand III I, I, and IIL D II, III, and Iv Which statements are true about the nucleus? 1 II m Iv oou> Nucleoplasm contains DNA and RNA. Nucleus acts as the control centre of a cell. Nucleus is present in all mature eukaryotic celis. Nucleus is surrounded by a double lipoprotein membrane. 1, Land lV I, and It II, Ii and IV 1, 1, land IV Which molecule can easily cross the lipid bilayer without the aid of membrane protein? gae> Glucose Oxygen Amino acid Sodium ion 6 DEPARTMENT OF SCIENCES PROGRAMME, CFSTIUM14 15 16 MID-SEMESTER/SI/11-12/SHF1415 Why do water molecules need transport proteins to move across the plasma membrane? I Water has a neutral pH. Il Water is a polar molecule. III Water is a charged molecule. IV__ Water is a hydrophilic molecule. A Tand I B Tand IIT c Il and IV D IL and Ill In a recent research on fat metabolism, it was shown that some aquaporins allow passage of glycerol but not hydronium ion (H30*). Which of the following is the most significant factor that allows the Passage of glycerol molecule but not the hydronium ion? Size of molecule Charge of molecule Polarity of molecule Molecular weight of molecule ooup> Which of the following are examples of enzyme cofactor? I Toxin 1 Heme Il Flavin IV Succinate A TandIr B Iland Ir c Tand IV D III and IV 7 DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUM19 MID-SEMESTER/SI/11-12/SHF1415 Which statement below is not true about enzyme inhibition? A B c D In noncompetitive (reversible) inhibition, the inhibitor binds to the allosteric site of the enzyme. In noncompetitive (irreversible) inhibition, a poison binds to the enzyme and changes its conformation. In competitive inhibition, the inhibitor binds to the active site and changes the conformation of the enzyme. In competitive inhibition, the inhibitor competes with the substrate to bind to the active site of the enzyme. Figure 2 shows an example of an enzyme catalyzed reaction. Alcohol Ethanal + NADH ——————————+ Ethanol + NAD dehydrogenase Figure 2 What is the class of enzyme in the above reaction? oomD Oxydoreductase Isomerase Hydrolase Lyase What happens to the brain cells if they receive a stop signal at the G; checkpoint? A a c D They will stop divide permanently. They will move directly into telophase. They will complete the cycle and divide. They will exit the cycle and switch to a non-dividing state. 8 DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUM20 MID-SEMESTER/SI/11-12/SHF1415 Table 1 shows the duration (in minutes) for each phase of the cell cycle. G and H are cells from different organisms. Cell Type G Ss G M G 18 24 12 16 H 18 48 14 20 Table 1 Which of the following best explains the difference between the S phases of G and H? H contains more DNA than G. G contains more RNA than H. G and H contain the same amount of DNA. H contains 48 times more DNA and RNA than G. oomp> 9 DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUMMID-SEMESTER/SI/11-12/SHF1415 Matric No: .. SECTION B [15 marks] ‘Answer all questions on the space provided in this question paper. 1 Figure 3 shows two types of fatty acid molecules, I and J. AR Se-¢-c-¢-C-C-C-C-C-C-H oO Pobre bg bb > HHHHAHHHHH H Molecule I cory Se-G-G-G-C-G-G=¢.d) | Oo feels aie eee eee 9 HH AHA Ce H 4 Molecule J Modified from : http://www.realfitnessblog.com/2008/11/30/dietary-fat-is-not the-enemy/ Figure 3 (a) Determine the type of fatty acid represented by I and J. Li [1] (b) What is the difference between the structure of molecule I and J? (c) What is the importance of ‘kinks’ in fatty acid molecule? 10 DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUMMID-SEMESTER/SI/11-12/SHF1415 (d) _ List two functions of fats other than as energy storage. [2] u DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUMMID-SEMESTER/SI/11-12/SHF1415 Figure 4 shows a type of inhibition in enzyme reaction. Substrate Substrate CC) ve Co) Active site Y Source : hi Figure 4 (a) Identify the type of inhibition shown in Figure 4. [1] (b) Briefly explain the mechanism of inhibition in the above reaction. (c) How can the effect of the inhibition be reduced? 12 DEPARTMENT OF SCIENCES PROGRAMME, CFSIIUM3 Relative concentration MID-SEMESTER/SI/11-12/SHF1415 Figure 5 shows the relationship between cyclin concentration and MPF activity in typical animal cells. Y x Z Time Figure 5 (a) Determine the phase of the cell cycle at time X. (b) What happen to the cells at time ¥? (c) (i) At which phase of mitosis MPF activity reaches Z? (ii) What is the role of MPF in the cell cycle? (d) How does cyclin concentration affect MPF activity? 13 DEPARTMENT OF SCIENCES PROGRAMME, CFSHIUMMID-SEMESTER/SI/11-12/SHF1415 SECTION C [15 marks] ‘Answer any one question on page 15 — 18 of this question pap (a) Explain the similar characteristics of mitochondria and chloroplasts. [7] (b) List down the intercellular junctions found in animal and plant cells. Briefly explain their functions. (a) _ Explain how sucrose is transported in plants cells. [7] (b) Explain how sodium and potassium ions are transported in the nerve cells. [8] END 14 DEPARTMENT OF SCIENCES PROGRAMME, CFSHIUM