FORM 4 BIOLOGY prepared by Mr Daryl Tan

1. All living things are made up of basic units called…..

A nucleus
B cells
C cytoplasm
D nucleoplasm

2. Diagram 1 shows an animal cell.

What is the structure labeled X?

A Nucleus
B Golgi apparatus
C Mitochondrion
D Rough endoplasmic reticulum

3. Which of the following cellular components is not found in an animal cell?

A C

B D

Biology 2018 Mid-year Exam 1

FORM 4 BIOLOGY prepared by Mr Daryl Tan

4. Which of the following organelles is covered with ribosomes on its outer surface?
A Smooth endoplasmic reticulum
B Rough endoplasmic reticulum
C Golgi apparatus
D Mitochondria

5. Diagram 3 shows an organism

The organism shown above reproduces by…

I. Forming spores
II. budding
III. binary fission
IV. regeneration

A. I and II
B I and III
C II and IV
D II, III, and IV

6. What are the main functions of the nervous system?

I. detects stimuli
II. transmit nerve impulses and integrates the activities of other systems
III. controls the physiological processors in conjunction with the endocrine system
IV. regulates the osmotic balance of the blood

A II and I
B III and II
C I, II and III
D I, II, III and IV

Biology 2018 Mid-year Exam 2

FORM 4 BIOLOGY prepared by Mr Daryl Tan

7.
 Defends the body against infection
 Returns excess tissue fluid to the
blood

The above statement refers to the …

A endocrine system
B lymphatic system
C muscular system
D excretory system

8. Which of the following are the physical factors that affect the internal environment
of organisms

I temperature
II blood pressure
III osmotic pressure
IV pH

A I and II
B II and IV
C I, II and III
D II, III and IV

9. Which of the following is not a plant organ?

A Leaves
B Stems
C Xylems
D Flowers

10. What will happen if plants do not have cell walls?

A Unwanted substances would enter the cell.
B Plant cells would lose their shape and rigidity.
C Useful substances would flow out of the cell.
D Activities of the cell cannot be carried out.

Biology 2018 Mid-year Exam 3

FORM 4 BIOLOGY prepared by Mr Daryl Tan

11. Diagram below shows the structure of a plasma membrane based on the fluid
mosaic model.

What is X and Y?
X Y
A Lipid Protein
B Protein Lipid
C Protein Phospholipid
D Phospholipid Protein

12. Which of the following processes involve diffusion?

I The intake of oxygen into the alveolus

II The absorbtion of glucose and amino acids by cells in the villi of the small
intestine.
III The absorbtion og digested food through the villi of the small intestine.
IV The intake of mineral ions by the root hairs of a plant.

A I and II only
B I and III only
C I, III and IV only
D I, II, III and IV

13. Which of the following processes is involved in the transport of sodium ions against
the concentration gradient?
A Osmosis
B Active transport
C Simple diffusion
D Facilitated diffusion

Biology 2018 Mid-year Exam 4

FORM 4 BIOLOGY prepared by Mr Daryl Tan

14. Which of the following molecules move across the plasma membrane by simple
diffusion?
I Water
II Oxygen
III Starch
IV Carbon dioxide

A I and II only
B I, II and IV only
C II, III and IV only
D I, II, III and IV

15. An experiment is carried to study the movement of substances across the Visking
tubing. The result of the Benedict’s test and the iodine test at the beginning and at
the end of the experiment are shown in table in below.

Test Colour of the liquid in boiling tube

Beginning of experiment End of experiment
Benedict’s Blue solution Brick red precipitate
test
Iodine test Brown solution Brown solution

What inference can be made from the experiment?

A The Visking tubing is permeable to glucose molecules.

B The Visking tubing is permeable to starch molecules.
C The Visking tubing is permeable to both glucose and starch.
D The Visking tubing is not permeable to glucose and starch molecules.

16. Which of the following processes involves active transport?

A Uptake of icons by root hair cells of a plant
B Absorption of digested food in the villus
C Absorption of water by root hair cells of a plant
D Gaseous exchange between the alveoli and the blood capillaries.

Biology 2018 Mid-year Exam 5

FORM 4 BIOLOGY prepared by Mr Daryl Tan

17. Diagram 7 shows the structure of a plant cell before and after it has been immersed
in solution P.

What is solution P and the process that takes place in the plant cell?

Solution P Process

A Distilled water Plasmolysis

B Distilled water Deplasmolysis

C 10% sucrose Plasmolysis

solution
D 15% sucrose Haemolysis
solution

18. The diagram shows a strip of a mustard green after it has been immersed in
solution Z.

Which of the following is solution Z?

A 0.1% salt solution
B distilled water
C 1.5% sucrose solution
D 30% sucrose solution

Biology 2018 Mid-year Exam 6

FORM 4 BIOLOGY prepared by Mr Daryl Tan

19. A piece of an onion epidermis is placed in 30% sucrose solution. Which of the
following shows the shape of the cells after 30 minutes.

Biology 2018 Mid-year Exam 7

FORM 4 BIOLOGY prepared by Mr Daryl Tan

20. Which of the following correctly describes the effects of excessive use of chemical
fertilisers?

I the soil solution becomes hypertonic

II the roots cells become flaccid
III the plasma membrane of the root cells are destroyed
IV Causes wilting in plant
A II and IV only
B I.II,ang IV only
C II,III,and IV only
D I,II,III,and IV

21. Which of the following substance acts as a medium for biochemical reactions in a
cell?
A Water
B Lipid
C Glucose
D Amino acid

22. The diagram shows the structure of a nucleotide.

What are represented by the units labeled as X, Y and Z?

X Y Z
Phosphate Nitrogenous Sugar
group base
Phosphate Sugar Nitrogenous
group base
Sugar Phosphate Nitrogenous
group base
Nitrogenous Sugar Phosphate
base group

Biology 2018 Mid-year Exam 8

FORM 4 BIOLOGY prepared by Mr Daryl Tan

23. Which of the following carbohydrates are examples of polysaccharides?

I Starch
II Lactose
III Glycogen
IV Cellulose
A I, II and III only
B I, III and IV only
C II, III and IV only
D I, II, III and IV

24. Which of the following carbohydrates has a structure as shown in the diagram?

A Starch
B Glycogen
C Galactose
D Cellulose

25. Which of the following have the structure of a protein as shown in the diagram?

I Enzymes
II Antibodies
III Cholesterol
IV Haemoglobin
A I and II only
B I, II and IV only
C II, III and IV only
D I, II, III and IV

Biology 2018 Mid-year Exam 9

FORM 4 BIOLOGY prepared by Mr Daryl Tan

26. Which of the following statements about protein is not true?

A The monomer of protein is amino acid.
B Non-essential amino acids cannot be synthesized in humans
C The linear sequence of amino acids in protein molecule is called the primary
structure
D An example of a quartenary-structured proteins in haemoglobin

27. The main types of lipids are listed below, except…

A oils
B steroids
C hormones
D phospholipids.

28. The diagram shows a structure of one lipid molecule

The part labeled Q represents

A phosphate
B glycerol
C fatty acid
D amino acid

Biology 2018 Mid-year Exam 10

FORM 4 BIOLOGY prepared by Mr Daryl Tan

29. The diagram shows the mechanism of an enzyme reaction on a substance

What conclusion can be made about the characteristics of an enzyme?

I An enzyme reaction is very specific
II An enzyme reaction is affected by temperature
III An enzyme speeds up the rate of chemical reaction.
IV An enzyme remains unchanged at the end of the reaction.
A I and IV only
B II and IV only
C I, III and IV only
D I, II, III and IV

30. Which of the following graphs shows the effect of temperature on the rate of an
enzyme-catalysed reaction?

Biology 2018 Mid-year Exam 11

FORM 4 BIOLOGY prepared by Mr Daryl Tan

31. The diagram shows a stage in a cell division

This stage of cell division is

A metaphase
B anaphase I
C anaphase
D metaphase I

32. Which of the following shows the correct sequence for cell division?
I G2
II G1
III M
IV S
A I, II, III IV
B II, IV, I, III
C I, II, IV, III
D II, III, IV, I

33. Arrange the diagrams in the right

sequence for mitosis.

A IV, III, I, II
B I, IV, II, III
C III, II, I, IV
D II, I, IV, III

Biology 2018 Mid-year Exam 12

FORM 4 BIOLOGY prepared by Mr Daryl Tan

34. Which of the following cells shows the cell at the mitotic metaphase stage?

Biology 2018 Mid-year Exam 13

FORM 4 BIOLOGY prepared by Mr Daryl Tan

35. The figure shows the stages of division by mitosis

Which of the following shows the correct sequence of the events?

A S, Q, P, R
B R, Q, P, S
C Q, P, S, R
D P, Q, R, S

36. All somatic cells that are diploid originate from the
A gamete
B autosome
C chiasma
D zygote

Biology 2018 Mid-year Exam 14

FORM 4 BIOLOGY prepared by Mr Daryl Tan

37. The diagram shows a phase in nuclear division

What is this phase?

A prophase
B anaphase
C metaphase
D telophase

38. Which of the following statements are true about mitosis?

I produces two daughter cells that are diploid
II daughter cells are the same genetically as the parent cell
III chromatid pairs separate during the anaphase stage
IV homologous chromosomes undergo synapsis during the prophase stage.
A I and II only
B II and IV only
C I, II and III only
D II, III and IV only

39. Which of the following substances may bring harm to the process of mitosis and
meiosis?
I X-ray
II Fungicides
III Benzene
IV Mustard gas
A I and III only
B II and IV only
C I, II and IV only
D I, II, III and IV

Biology 2018 Mid-year Exam 15

FORM 4 BIOLOGY prepared by Mr Daryl Tan

40. The diagram shows an animal cell at one of the stages in meiosis.

Which of the following is the number of chromosomes in the daughter cells after the
division?
A n=2
B n=4
C n=8
D n = 16

41. The following statements are about an organelle of a cell.

 Exists freely in the cytoplasm or is attached to the rough

endoplasmic reticulum.
 Site of the protein synthesis

What is the organelle?

A Vacuole C Golgi body
B Nucleus D Ribosome

Biology 2018 Mid-year Exam 16

FORM 4 BIOLOGY prepared by Mr Daryl Tan

42. The diagram shows the liquid composition of the human body.

Which of the following form the internal environment?

A P, Q, R C P, R, S
B Q, R, S D P, Q, S

43. Which of the following is a connective tissue?

A C

B D

Biology 2018 Mid-year Exam 17

FORM 4 BIOLOGY prepared by Mr Daryl Tan

44. What are the processes involved in the movement of water and mineral ions into
root hairs?

Water Mineral ions

A. Facilitated diffusion Osmosis
D. Active transport Osmosis
C. Osmosis Active transport
D. Osmosis Facilitated diffusion

45 Which of the following onion cells were immersed in a hypotonic solution?

Biology 2018 Mid-year Exam 18

FORM 4 BIOLOGY prepared by Mr Daryl Tan

46. The graph shows the changes in mass of potato strips immersed in different
concentrations of sucrose solution.

Based on the above graph which of the following concentrations of sucrose

solution should be used so that a flaccid potato strip regains its turgidity?
A 1.5 g per 100 ml C 3.5 g per 100 ml
B 2.5 g per 100 ml D 4.5 g per 100 ml

47 A plant cell is immersed in distilled water.

Which of the following is true about the movement of the water molecules in the
early stage ?
A No water molecules are entering or exiting the cell
B. The rate of water molecules entering and exiting the cell is the same
C. The rate of water molecules entering the cell is higher than exiting the cell
D. The rate of water molecules exiting the cell is higher than entering the cell

Biology 2018 Mid-year Exam 19

FORM 4 BIOLOGY prepared by Mr Daryl Tan

48 The diagram shows the molecular structure of three food classes.

Which food classes do X, Y and Z belong to?

X Y Z
A Carbohydrate Protein Lipid
B Protein Carbohydrate Lipid
C Protein Lipid Carbohydrate
D Lipid Carbohydrate Protein

Biology 2018 Mid-year Exam 20

FORM 4 BIOLOGY prepared by Mr Daryl Tan

49. Diagram below shows the rate of enzyme hydrolysis reaction, R and S in the
human body.

Which of the following is true about enzymes R and S?

Enzyme R
A Secreted in the stomach
B The active site changes at pH
more than 4
C R is trypsin
D Synthesized in the rough in the
endoplasmic reticulum
Enzyme S
Secreted into the duodenum
The active site changes at pH
more than 7
S is lipase
Synthesized in the smooth
endoplasmic reticulum

50 The diagram below shows the breaking down of complex molecules by an

enzyme. Which of the molecules A, B, C and D represents the substrate?

Biology 2018 Mid-year Exam 21