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How Organic Chemistry Convinced Me of

the Creator
by Steve Moody

Facts in the field of stereochemistry prove the need for a Creator.

Against all odds, billions of proteins in our bodies have the same
chemical “handedness”!
The apostle Paul said that God reveals Himself in the creation. He wrote, “For since the creation of the world
His invisible attributes are clearly seen, being understood by the things that are made” (Romans 1:20).

The only real alternatives for explaining the existence of matter and life are evolution or God.

Evolutionists have claimed that the building blocks of life can be formed by random natural processes.
(Consider the famous Miller-Urey experiment that produced some amino acids.) But, beyond the incredible
odds against all the necessary parts forming and assembling themselves mindlessly into something much more
complex than a jetliner, there is another problem for evolution.

Even the three-dimensional orientation of the molecules of life gives evidence of a Creator!

Chemical complexity
We believe God created atoms, molecules and all the laws that govern reactions. He created the science of
chemistry.

Within the study of stereochemistry (the study of molecular structure in three dimensions) is the study of
stereoisomerism. Isomers in general are chemical compounds with the same chemical formula but that differ
in chemical structure. Ethyl alcohol and methyl ether consist of the same atoms in the same proportion and
thus have the same atomic weights and the same formulas—C2H6O—but they differ in structure (see Diagram
1).

Stereoisomers are a special type of isomer. They also have the same chemical formulas; however, they only
differ from one another “in the way the atoms are oriented in space.” They “are like one another with respect to
which atoms are joined to which other atoms” (Robert Thornton Morrison and Robert Neilson Boyd, Organic
Chemistry, 1966, p. 70). See Diagram 2 below.

And getting even more specific, there is one type of stereoisomer that is important in the proof of God’s
existence—enantiomers. Enantiomers come in two mirror-image forms, each of which is equally likely to form
in nature. But, against all odds, usually only one enantiomer of a pair occurs in plants and animal tissues and
systems. As we will see, the existence of only one enantiomer of a pair is impossible in nature if all of these
substances developed by random chance as evolution claims.

How organic chemistry convinced me of the Creator

While studying organic chemistry in my third year at pharmacy school, I also began studying the Bible. I saw
that in order to follow the teachings of God in the Bible, I would have to make some major changes in my
thinking and living. But before making these changes, I wanted to find real proof of God’s existence.

I found that proof in an unexpected place.

I had already learned that, in simple terms, it takes a pure enantiomer to produce a pure enantiomer (i.e., it
takes one to produce one). The question arose: From where did the first pure enantiomer originate?

(Note that scientists use several words to describe enantiomers. They are called chiral—from the Greek word for
hand—because they have mirror-image right-hand and left-hand forms. They are also called optically active
since they can be detected using polarized light that is rotated to the right or left when passing through the
molecules.)

While studying stereoisomerism I came across the following paragraph in my textbook:

“Some optically active compounds are obtained from natural sources since living organisms usually produce
only one enantiomer of a pair. …

I understood that the

“Indeed, we deal with optically active substances to an extent that
we may not realize. We eat optically active bread and optically active
meat, live in houses, wear clothes, and read books made of optically
existence of just one
active cellulose. The proteins that make up our muscles and other
tissues, the glycogen in our liver and in our blood, the enzymes and enantiomer of a pair in
hormones that enable us to grow, and that regulate our bodily
processes—all these are optically active. Naturally occurring plants and animals in
compounds are optically active because the enzymes that bring
about their formation—and often the raw materials from which they
nature is impossible by
are made—are themselves optically active. As to the origin of the natural processes
optically active enzymes, we can only speculate” (ibid., p. 231,
emphasis added). alone. They can only
 exist as they do as the
Man does not know where the first optically active compounds
originated, because he does not recognize God as the Creator. In the
margin of my textbook by this paragraph I put a big asterisk and
result of the creative
wrote EVIDENCE OF GOD’S CREATION.
work of God.
Why did I write this? I understood that the existence of just one
enantiomer of a pair in plants and animals in nature is impossible by
natural processes alone. They can only exist as they do as the result of the creative work of God. The proof of
this fact is the purpose of this article.

Mirror images
Enantiomers are stereoisomers whose molecular structures (how the atoms are arranged in space) are mirror
images of each other. (See again Diagram 2, which shows the two enantiomers of chloroiodomethanesulfonic
acid.)

To better picture mirror-image molecules, think of your hands. When you put your hands together, the thumbs
and fingers on both hands all match each other. They are superimposed as if placing one hand on a mirror.
However, if you face both of your palms in the same direction away from you, and then place one hand on top
of the other, the thumbs and fingers are no longer superimposed. The thumb of each hand is now matched
with the little finger of the other hand. The only fingers that are superimposed are the middle fingers.

By definition, enantiomers are mirror images of each other. They have the same formulas; but, being mirror
images of each other, some of their atoms are not superimposable when the molecules are oriented in the same
direction.

In Diagram 2 above, when the two molecules are oriented in the same direction, the chlorine atoms would be
superimposed with the iodine atoms. The unique feature of enantiomers is that they all have mirror-image
molecules.

Production of enantiomers
When enantiomers are made randomly from raw materials, the product is always a 50-50 mixture of the two
possible enantiomers of each pair. This is due to the 50-50 chance that an added atom or functional group
(radical) would attach to either the left-hand or right-hand side of the target carbon atom since the target area
is spatially flat.

This pair of enantiomers (in a 50-50 mixture) cannot be separated into a 100-percent pure product of either
enantiomer by ordinary means since the only physical property that differentiates the two molecules is how
each affects plane-polarized light (optical activity).

A pure solution consisting of only a single enantiomer is optically active. It will rotate plane-polarized light
either to the right or left by a certain degree unique to that pair. The amount of rotation is the same. The
difference between the two enantiomers in each pair is the direction of the rotation—right for one and left for
the other.
Other physical properties of an enantiomer pair are identical. As a result, they cannot be separated by most
normal physical means. The two molecules have the same boiling points, so they cannot be separated by
fractional distillation. They have the same solubility in a given solvent, so they cannot be separated by
fractional crystallization. And, since they are held equally strongly by a given absorbent, they cannot be
separated by chromatography.

“The separation of a racemic modification [50-50 mixture] into enantiomers … is therefore a special kind of
job, and requires a special kind of approach” (ibid., p. 83).

These special methods require the use of a pure enantiomer (which only comes from living things in nature) or
intelligent intervention by human beings. Without intelligent intervention, the only way a mixture can be
separated into pure enantiomers is through the use of optically active reagents. We must have one to produce
one.

Yet we find pure enantiomers in abundance in living things. These could only exist if they were created by God.
They cannot exist as a result of the random chance formation of molecules from atoms that evolution requires.
Any random chance combination of raw materials would only produce a 50-50 mixture.

In spite of that, in living things, 100-percent pure enantiomers are everywhere. In fact, in living things the
usual situation is that only one enantiomer of a pair is found.

Why these impossible but necessary pure enantiomers are vital for life
Even though the mirror-image molecules have the same composition, they have much different effects on living
things. The other enantiomer, when produced, is found to be useless or even harmful. “Despite their close
similarity, one isomer of such a pair may serve as a nourishing food, or as an antibiotic, or as a powerful heart
stimulant, and the other may be useless” (ibid., p. 70).

“In biological systems … such stereochemical specificity is the rule rather than the exception, since the all-
important catalysts, enzymes, and most of the compounds they work on, are optically active. The sugar (+)-
glucose plays a unique role in animal metabolism and is the basis of a multimillion dollar fermentation
industry; yet (–)-glucose is neither metabolized by animals nor fermented by yeasts. When the mold
Penicillium glaucum feeds on a mixture of enantiomeric tartaric acids, it consumes only the (+)-enantiomer and
leaves (–)-tartaric acid behind. The hormonal activity of (–)-adrenaline is many times that of its enantiomer;
only one stereoisomer of chloromycetin is an antibiotic. (+)-Ephedrine not only has no activity as a drug, but
actually interferes with the action of its enantiomer. Among amino acids, only one asparagine and one leucine
are sweet, and only one glutamic acid enhances the flavor of food” (ibid., p. 82).

As Charles McCombs, who has a Ph.D. in organic chemistry, explains, evolution has deep problems with
chirality:

“As nucleotide molecules come together to form the structure of DNA, they develop a twist that forms the
double helix structure of DNA. DNA develops a twist in the chain because each component contains chirality or
handedness. It is this handedness that gives DNA the spiral shaped helical structure. If one molecule in the
DNA structure had the wrong chirality, DNA would not exist in the double helix form, and DNA would not
function properly. The entire replication process would be derailed like a train on bad railroad tracks.

“In order for DNA evolution to work, billions of molecules within our body would have to be generated with the
‘R’ [right-handed] configuration all at the same time, without error. If it is impossible for one nucleotide to be
formed with chirality, how much less likely would it be for billions of nucleotides to come together exactly at
the same time, and all of them be formed with the same chirality? If evolution cannot provide a mechanism
that forms one product with chirality, how can it explain the formation of two products of opposite chirality?”
(“Evolution Hopes You Don’t Know Chemistry: The Problem With Chirality,”
http://www.icr.org/article/evolution-hopes-you-dont-know-chemistry-problem-wi/).

The conclusion: The tissues and systems found in living things are filled with 100-percent pure enantiomers
that do not randomly form in a pure state in nature. The first 100-percent pure enantiomers must have been
created by God.

Read more about creation and evolution in our other articles on the subject, starting with “Intelligent Design:
Can Science Answer the Question, Does God Exist?”

About the Author

Steve Moody
Steve Moody graduated from Ambassador College in Pasadena, California, in June of 1971. He met his
lovely wife and lifelong companion, Vivian, while in college. They married a few days following his
graduation.
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