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The circulatory system is also known as the body's transport system. It regulates the flow of nutritive
fluids and materials, waste substances, and water in the bodies of living organisms. Its main functions
are to deliver food and oxygen to the cells and to pick up the cells waste materials and carbon dioxide.
Your circulatory system consists of the blood, the blood vessels, and the heart
Blood Plasma
Plasma is not all liquid. It is 90% fluid. It comprises 50 to 60% of your blood. The clear, yellowish liquid
part is called serum. As your blood reaches the capillaries, part of your blood serum leaks out through
the capillary vessel walls. It is finally collected into tiny
lymph vessels and then flows into larger veins.
The solid materials which form 10% of your plasma are the inorganic minerals and digested food
substances. The inorganic minerals dissolved in water give the plasma a salt content of about 1%
compared to that of seawater which is approximately 3%. This composition explains why blood is a little
salty.
Digested food substances are present in the form of glucose, fatty acids, glycerol, and amino acids which
are transported to the liver and other places for storage.
The plasma transports your blood cells, particularly the red blood cells. It carries food to the cells and
picks up waste materials. This fluid also contains antibodies or substances that
protect your body from infection.
Blood cells
The solid components of the blood are the red blood cells or erythrocytes; white
blood cells, or leucocytes; and platelets, or thrombocytes.
Your red blood corpuscles (RBC) or erythrocytes are very small, round, disc-shaped cells which are
thinned out in the center. They are so tiny that 75 billion of them will fit into a tube of 2.5-cm diameter.
They are elastic; therefore, they can be squeezed out of shape but they can easily go back to their
normal form.
In your study of bones, you learned about the bone marrow. It is here where the red blood cells are
formed. A young red blood cell has a nucleus like any other cell. As it matures, its nucleus disappears.
The mature red blood cell then leaves your bone marrow and passes into your bloodstream where it
serves its main functions.
Each erythrocyte contains more than 200 million molecules of hemoglobin. This protein substance
contains iron and carries oxygen. It also gives the erythrocyte its red color.
The erythrocytes are the special carriers of your blood. They deliver oxygen to your body tissues and
cells. They also pick up the unnecessary wastes and carbon dioxide from your cells. The total surface
area of all your red blood cells is greater than that of a football field. Such an equation explains why its
oxygen-carrying capacity is also great. There are normally between 4.5 and 5.5 million red blood cells
per cubic millimeter of your blood.
Your red blood cells also contain the proteins that determine blood type. There are the antigens and are
found on the cell membranes. An antigen is any molecule that causes the synthesis of an antibody when
the molecule is injected into another organism. It produces agglutination whenever different types of
blood are mixed. The RBC are usually the ones that form clumps.
The white blood cells (WBC) or leucocytes are the wandering cells in your blood. They circulate in the
bloodstream and have nothing to do with the delivery of food and oxygen. Their job is to protect your
body against foreign-invading substances, particularly bacteria. Leucocytes are true cells having their
own nuclei. Sometimes the nuclei are big; sometimes there are more than one. Leucocytes are also
fewer in number than the red cells, about 5,000 to 9,000 per cubic millimeter of blood. They occur in
different varieties under two general groups: the phagocytes and the lymphocytes. The phagocytes
engulf foreign substances, while the lymphocytes produce antibodies to attack your body enemies. Your
blood platelets, or thrombocytes, are the smallest blood cells. Their number ranges from 20,000 to
500,000 per cubic millimeter of blood. Platelets are useful to your body because they contain and
release a substance called thromboplastin, a type of protein needed for blood clotting. Platelets also
help to plug leaks in broken capillary walls. What would happen if your platelet count is too low?
Blood clotting
Have you ever had a cut which bled for a while? Did you notice that your cut formed a dark red scab or
clot that stopped the bleeding? This is called a blood clot.
Blood clotting begins when a blood vessel is injured. Blood comes into contact with the tissue around
the injury. Several substances, such as calcium and protein, combine or unite to trap the red and white
cells and form a mesh. This clot then plugs the leak caused by the wound. It also becomes the
foundation on which the new tissue will be built to heal your wound.
Blood Vessels
The blood flows throughout your body just as buses and cars travel through roads or highways. The
highways are the tubes of muscular tissues which we call blood vessels. Your blood vessels are the
arteries, the capillaries, and the veins.
Coronary Circulation
How does your heart get its nourishment? Food and oxygen for your heart are supplied by your blood.
The blood that feeds your heart, however, is not the same as the one that passes through the four
chambers. Your heart is fed by blood passing through its own coronary arteries, which are little
branching "trees" with trunks not much larger than soda straws. These arteries also branch out of the
aorta and lead to capillaries that are deeply embedded within the thick muscles of your heart. After
passing through these capillaries, the coronary blood supply moves into coronary veins leading to the
right atrium. The cycle of blood flow is then repeated until blood is completely oxygenated
Pulmonary Circulation
The contraction of the right ventricle of your heart forces the blood into the pulmonary artery. This
venous blood, charged with carbon dioxide, enters your lungs, passing through capillaries. It gives up
carbon dioxide taken from the body cells and receives a fresh supply of oxygen. This arterial blood then
passes through the pulmonary veins in the left chamber of your heart. The circulation therefore involves
the lungs as the oxygen supplies of your blood coming from your body and your heart.
Systemic Circulation
Systemic circulation involves the heart, blood vessels, and all body parts.
Arterial blood is forced from the left atrium to the left ventricle of your heart. The ventricle then
contracts, forcing the blood through the aorta. The blood then passes through the branches, the arteries
whose diameters have gradually diminished. These arteries lead in turn to several arterioles, which
again branch into the capillaries. It is in the capillaries where the exchange of food and gases and the
removal of cell wastes occur. Venous blood then travels from the veins connected to the capillaries to
the two largest veins in the system: the inferior and superior vena cava, which serve as entrances to the
heart.