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Journal of Clinical Child & Adolescent Psychology

ISSN: 1537-4416 (Print) 1537-4424 (Online) Journal homepage: https://www.tandfonline.com/loi/hcap20

Future Directions for Psychosocial Interventions


for Children and Adolescents with ADHD

George J. DuPaul, Steven W. Evans, Jennifer A. Mautone, Julie Sarno Owens &
Thomas J. Power

To cite this article: George J. DuPaul, Steven W. Evans, Jennifer A. Mautone, Julie Sarno Owens
& Thomas J. Power (2020) Future Directions for Psychosocial Interventions for Children and
Adolescents with ADHD, Journal of Clinical Child & Adolescent Psychology, 49:1, 134-145, DOI:
10.1080/15374416.2019.1689825

To link to this article: https://doi.org/10.1080/15374416.2019.1689825

Published online: 04 Dec 2019.

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Journal of Clinical Child & Adolescent Psychology, 49(1), 134–145, 2020
Copyright © Society of Clinical Child & Adolescent Psychology
ISSN: 1537-4416 print/1537-4424 online
DOI: https://doi.org/10.1080/15374416.2019.1689825

FUTURE DIRECTIONS

Future Directions for Psychosocial Interventions for


Children and Adolescents with ADHD
George J. DuPaul
Department of Education and Human Services, Lehigh University

Steven W. Evans
Department of Psychology, Ohio University

Jennifer A. Mautone
Department of Pediatrics, Children’s Hospital of Philadelphia and Perelman School of Medicine,
University of Pennsylvania

Julie Sarno Owens


Department of Psychology, Ohio University

Thomas J. Power
Department of Pediatrics, Children’s Hospital of Philadelphia and Perelman School of Medicine,
University of Pennsylvania

Multiple psychosocial interventions are efficacious for children and adolescents with attention-
deficit/hyperactivity disorder (ADHD) including behavioral parent training, behavioral classroom
management, behavioral peer interventions, and organization training programs. Unfortunately,
there is a significant gap between research and practice such that evidence-based treatments often
are not implemented in community and school settings. Using a life course model for ADHD
treatment implementation, we discuss future research directions that support movement from the
current, fragmented system of care to a more comprehensive, integrated, and multisystemic
approach. Specifically, we offer six recommendations for future research. Within the realm of
treatment development and evaluation, we recommend (1) identifying and leveraging mechanisms
of change, (2) examining impact of youth development on treatment mechanisms and outcomes,
and (3) designing intervention research in the context of a life course model. Within the realm of
implementation and dissemination, we recommend investigating strategies to (4) enhance access to
evidence-based treatment, (5) optimize implementation fidelity, and (6) examine and optimize costs
and cost-effectiveness of psychosocial interventions. Our field needs to go beyond short-term,
efficacy trials to reduce symptomatic behaviors conducted under ideal controlled conditions and
successfully address the research-to-practice gap by advancing development, evaluation, imple-
mentation, and dissemination of evidence-based treatment strategies to ameliorate ADHD-related
impairment that can be used with fidelity by parents, teachers, and community health providers.

Address correspondence to George J. DuPaul, School Psychology


Children and adolescents with attention-deficit/hyperactivity
Program, College of Education, Lehigh University, 111 Research Drive, disorder (ADHD) experience significant deficits in academic
Bethlehem, PA 18015. E-mail: gjd3@lehigh.edu and/or social functioning that typically begin early in life and
Color versions of one or more of the figures in the article can be found extend into emerging adulthood and beyond (American
online at www.tandfonline.com/hcap.
INTERVENTIONS FOR ADHD 135

Psychiatric Association, 2013; DuPaul & Langberg, 2015). interviewing techniques (Sibley et al., 2016), and cognitive
Symptomatic behaviors of inattention and/or hyperactivity- approaches (Boyer, Geurts, Prins, & Van Der Oord, 2015;
impulsivity disrupt development of self-regulation skills; Sprich, Safren, Finkelstein, Remmert, & Hammerness, 2016;
negatively impact academic performance and achievement; Vidal et al., 2015). In addition, family therapy approaches that
are associated with higher than average risk for special educa- were identified as relatively ineffective by Barkley and collea-
tion eligibility, grade retention, and school-dropout; and lead gues (Barkley, Edwards, Laneri, Fletcher, & Metevia, 2001),
to problematic relationships with peers and authority figures have been revisited and enhanced for adolescents with ADHD
(e.g., parents, teachers) (Barkley, Murphy, & Fischer, 2008; with some promise (Fabiano et al., 2016; Sibley et al., 2016).
Frazier, Youngstrom, Glutting, & Watkins, 2007; Hechtman, Unfortunately, there is a significant gap between research
2017; Mikami, 2010; Normand et al., 2013). Given the rela- and practice such that evidence-based treatment strategies often
tively high prevalence rate of 8 to 11% for ADHD (Danielson are not implemented in community and school settings. For
et al., 2018), this disorder is very costly in terms of health care example, only about 31% of families of children with ADHD
and educational expenditures (Chorozoglou et al., 2015; Robb have received behavioral parent training compared to 91%
et al., 2011). Thus, it is critically important that effective having ever received psychotropic medication (Danielson,
interventions are implemented across home, school, and com- Visser, Chronis-Tuscano, & DuPaul, 2018). A recent Office of
munity settings to not only reduce ADHD symptoms but also Inspector General report indicated that 45% of Medicaid-
attenuate potentially chronic functional impairments. enrolled children with ADHD who were newly medicated did
Multiple psychopharmacological and psychosocial not receive behavior therapy as part of their treatment (US
interventions have been established as effective for treat- Department of Health and Human Services, 2019). In addition,
ment of ADHD symptoms and associated impairments. only about 32% of students with ADHD are reported to receive
Psychopharmacological regimens primarily include cen- classroom behavior management (DuPaul, Chronis-Tuscano,
tral nervous stimulants such as methylphenidate, but also Danielson, & Visser, 2019). The underutilization of evidence-
non-stimulant drugs (e.g., atomoxetine) (Conner, 2015). based psychosocial treatment for children with ADHD is likely
In similar fashion, psychosocial treatments including due, in part, to the limited training that education, health, and
behavioral parent training, behavioral classroom manage- mental health professionals receive in evidence-based practices,
ment, behavioral peer interventions, organization training the scant availability of and access to services, as well as
programs, and, to a lesser extent, academic interventions challenges related to delivery of treatment across systems
are effective and associated with medium to large effects (e.g., home, school, healthcare).
on ADHD symptoms and related functional impairments The purpose of this article is to identify future research
(DuPaul, Eckert, & Vilardo, 2012; Evans, Owens, directions that would support movement from the current, oft-
Wymbs, & Ray, 2018; Fabiano, Pelham et al., 2009). fragmented, and inconsistently implemented system of care to
For many years, the foundation of psychosocial treatment a more integrated, multisystemic, longitudinal approach. We
for youth with ADHD has been behavioral treatment (Pelham first briefly describe a life course model for ADHD treatment
& Fabiano, 2008). Clinicians trained parents or teachers how implementation across family, school, and health care systems.
to manipulate contingencies in the home or school setting to This model provides a context for prioritizing research initia-
increase the likelihood of children with ADHD following tives. Next, we present a hypothetical case of a young child with
rules, staying on task, and being productive. Although tech- ADHD to describe treatment strategies typically implemented
niques taught to parents and teachers took many forms (e.g., across settings and the child’s development. We use this case to
daily report card, token economy, time out from positive illustrate limitations of treatment content and procedures over
reinforcement), the mechanism of action for most of these time in the context of current knowledge. Finally, we make
was to manipulate the way that punishment and reinforcement specific recommendations for research that address these
were provided, make the contingencies consistent and clear to limitations.
the child, and track the child’s’ responses. Much of the recent
research on behavioral approaches have been focused on
helping adults learn these techniques and effectively imple- LIFE COURSE MODEL FOR TREATMENT OF ADHD
ment them over time (e.g., Chacko et al., 2008; Fabiano,
Chacko et al., 2009; Owens et al., 2017). We previously proposed a model for treatment of ADHD
During the last decade, psychosocial treatments for ADHD that emphasizes a life-course perspective to address the
have gone beyond behavioral approaches (see Evans, Owens, long-term implications and outcomes of early life experi-
& Power, 2019; Evans et al., 2018). The expansion in ences on health, psychological, and educational outcomes
approaches has been driven to a large extent by a focus on of individuals with ADHD across the life span (Evans,
developing effective psychosocial treatments for adolescents, Owens, Mautone, DuPaul, & Power, 2014). In contrast to
including training interventions (Evans et al., 2016; Langberg, prevailing models of care that focus on service delivery to
Epstein, Becker, Girio-Herrera, & Vaughn, 2012), motivational individuals emphasizing short-term symptom reduction, the
136 DUPAUL ET AL.

life-course model prioritizes helping youth with ADHD a sustained fashion with consistency across school years,
improve competencies and develop into independent, and James’s parents were not routinely included in plan
healthy adults who achieve occupational, personal, and development. James began receiving psychostimulant med-
recreational success. Briefly, this model is comprised of ication from his primary care provider when he was
four layers of services including (1) foundational strategies in second grade with treatment continuing in various for-
to establish appropriate structure and supports in home and mulations and dosages throughout his school years.
school (e.g., parent-teacher communication), (2) psychoso- Although medication reduced his ADHD symptoms to
cial interventions to increase competencies and address a significant degree, he continued to experience consider-
impairments in academic, behavioral, and social function- able academic and social impairment. In addition, his par-
ing (e.g., organization interventions), (3) medication treat- ents were reluctant to let school personnel know about
ment, and (4) accommodations to adapt environments to James’s medication treatment, i.e., there was a significant
children’s limitations (i.e., reductions in expectations). disconnect between home and school systems of care for
These layers represent the sequence within which services James.
should be delivered and combined over time and across In middle and high school, James exhibited increasing
systems and settings. The life course model includes seven difficulties with organization, and study and time manage-
principles for service delivery including the need to: (a) ment skills. With school personnel assistance, James’s par-
understand contextual and cultural factors, (b) promote ents intermittently implemented homework management
treatment engagement of parents and youth, (c) tailor inter- programs (i.e., inconsistent treatment fidelity). School
ventions to child’s developmental level, (d) design inter- counselors also met with James periodically to help him
ventions to meet individual child and family needs, (e) with his study skills and time management. By high school,
facilitate alliances within and between systems, (f) offer James started to develop symptoms of depression (negative
implementation supports for intervention providers, and (g) self-cognitions, withdrawal from social activities). Despite
conduct progress monitoring to evaluate treatment these various treatment efforts over the years, he experi-
response. The hypothetical case below describes common enced consistent difficulties with school grades, building
barriers faced by families as they attempt to receive treat- and maintaining friendships, and developing recreational
ment for ADHD across their child’s development, high- interests beyond social media and video games. Stated
lighting the need for a life course approach to care and differently, although the combination of psychosocial treat-
closures in the research-to-practice gap. ment strategies and medication led to periodic improve-
ments in James’s ADHD symptoms and related
impairments, these were never sustained over time nor
was his functioning normalized (i.e., commensurate with
THE CASE OF “JAMES” academic and social functioning of his peers). Failure to
achieve and sustain substantial gains may have been due to
James is a boy who lives with his biological parents and several factors including lack of access to evidence-based
two siblings (9-year-old brother, 2-year-old sister) in care (e.g., behavioral parent training), inconsistent treat-
a small urban community in the northeastern US. Since ment implementation fidelity, as well as inherent limitations
toddlerhood, James displayed significant inattention and of extant short-term treatment strategies (e.g., effects unli-
hyperactive-impulsive behaviors across home and school kely to generalize across settings and over time without
settings such that he was expelled from two different pre- direct programming that is cross-situational and sustained).
schools due to his disruptive activity. Based on this history, The impact of treatment on James’s development also may
when James was four, his primary care provider diagnosed have been limited by inconsistent collaboration and com-
James with ADHD and oppositional defiant disorder munication across home, school, healthcare, and commu-
(ODD) and suggested that James start a low-dose of nity systems. These are among the many areas that should
a psychostimulant medication. Because his mother knew be prioritized for empirical investigation to enhance out-
her neighbor had a bad experience with this type of med- comes for children like James.
ication, she declined to fill the prescription.
James experienced significant academic (low report card
grades, inconsistent work completion) and behavioral (e.g.,
inattention to instructions, disruptive verbal and physical RECOMMENDATIONS FOR FUTURE RESEARCH
actions) difficulties as he entered and progressed through IN TREATMENT DEVELOPMENT AND
elementary school. He also experienced a great deal of EVALUATION
difficulty making and keeping friends. His teachers
attempted a variety of interventions including token rein- Given the limitations highlighted in the case of James, we
forcement programs and daily behavior report card sys- offer three recommendations within the realm of treatment
tems; however, none of these were implemented in development and evaluation and three recommendations
INTERVENTIONS FOR ADHD 137

Future Challenge 1: Treatment Development and Evaluation


Future Challenge 2: Implementation and Dissemination

Primary Care System Family

The Client

Infancy…..Toddlerhood…Childhood….Adolescence…..Young Adulthood.

School System Mental Health System

FIGURE 1 Challenges to psychosocial treatment of youth with ADHD across systems and development.

within the realm of implementation and dissemination (see Behavior Modification


below). Collectively, these recommendations directly
The core elements of a behavioral approach to treatment
address challenges to psychosocial treatment of ADHD
have historically focused on the use of operant and classical
within and across family, school, primary care, and mental
conditioning by parents and teachers. Some research exists
health systems, affirming the child’s long-term develop-
indicating that much of the impairment associated with
ment as a priority (see Figure 1).
ADHD reflects a performance deficit, not a skills acquisition
deficit (e.g., Aduen et al., 2018). This finding may explain
why psychoeducation approaches are not effective with these
Recommendation 1: Identify and Leverage children (e.g., traditional social skills training; Evans et al.,
Mechanisms of Change 2018), but can be effective when taught in the context of an
intensive behavioral program that uses operant conditioning
In order to adequately address the system of care issues, principles to address performance deficits (Pelham et al.,
there needs to be effective treatments and we do not yet 2014). In addition, there has been research on malleable
have an adequate arsenal to effectively treat children and characteristics of children with ADHD that may explain the
adolescents with ADHD. The development and evaluation effectiveness of behavior modification approaches, such as
of new treatments is most effective when guided by theory reward sensitivity (Tenenbaum et al., 2018; Tripp & Alsop,
and evidence of mechanisms of change. A variable can be 2001). Identification and an improved understanding of malle-
considered a mechanism of change that explains why able constructs that are causally related to impairment in
a treatment works, if the variable is malleable and causally children with ADHD will help us improve our behavioral
related to the impairment being treated (Carper, Makover, interventions and their long-term benefits.
& Kendall, 2018; Kazdin, 2007). As we consider the vari-
ety of treatments that have been evaluated for ADHD and
the development of new treatments, it is critical that future Cognitive Strategies
research explicitly focus on identifying mechanisms of Cognitive or cognitive behavioral therapy (CBT) has an
change that account for treatment effects and aligning inter- interesting history for youth with ADHD. The original putative
vention approaches to impact the identified mechanism. mechanism of change for CBT was that children with ADHD
Using three common treatment approaches described were not adequately thoughtful before acting and by teaching
below, we examine the status of research on mechanisms children to think out loud, one could improve their thoughtful-
of change related to each. ness, planning, and problem-solving prior to exhibiting
138 DUPAUL ET AL.

impulsive behaviors (e.g., Meichenbaum & Goodman, 1971). long-term benefits may meaningfully exceed those of other
Although one could teach children with ADHD to do this treatments (Evans et al., 2016). It may be that once skills are
during sessions, the skill rarely persisted after leaving the established through a training intervention, they become rou-
clinician. CBT reemerged in the last decade as a potential tine and persist longer than behaviors shaped by rewards.
approach to treating adolescents and adults with ADHD; how- Increasing our understanding of the mechanisms for training
ever, clinical trials of CBT with adolescents with ADHD have interventions can lead to development of optimally effective
not resulted in improvements in functioning (e.g., Boyer et al., approaches. In addition, training interventions have been
2015; Sprich et al., 2016; Vidal et al., 2015), and the potential applied to relatively few areas of impairment (e.g., study and
mechanism of change specifically related to ADHD has not organization skills) and evaluating them across the diverse
been clearly elucidated. Further, although negative self- range of functioning may yield new tools for treatment.
statements are commonly observed in adolescents with
ADHD (like James), and cognitions are likely malleable,
there is not yet evidence to suggest that they are causally related Recommendation 2: Examine Impact of Development
to the impairment that is specific to ADHD. In fact, it may be on Treatment Mechanisms and Outcomes
that adolescents and adults with ADHD develop these depres- In the first several decades of ADHD treatment research, there
sion-related cognitive factors as a result of persistent ADHD- was little focus on developmental level. For example, in the
related impairment over time and these factors are causally series of four evidence-based treatment reviews for youth with
related to the emergence of comorbid depression. This is con- ADHD that began in 1998 (Evans, Owens, & Bunford, 2014;
sistent with recent findings that almost 50% of young adoles- Pelham & Fabiano, 2008; Pelham et al., 1998), it was not until
cents with ADHD experience a decline in their self-worth, and the most recent version that levels of evidence were differen-
those with decreasing self-worth were more likely than their tiated based on ages of participants (Evans et al., 2018). Indeed,
peers with ADHD without decreasing self-worth to have higher all of the issues addressed previously in the discussion of
depressive symptoms at age 15 (Dvorsky, Langberg, Becker, & mechanisms of change are not static, as mechanisms are likely
Evans, 2019). In order to develop effective cognitive interven- to change across development. Thus, it is critical to identify
tions for youth with ADHD, there is a critical need to improve relevant mechanisms at each stage of development. However,
our understanding of cognitive factors that may be causally even if the mechanism remains the same across development,
related to impairment associated with ADHD and to develop treatment outcomes may also differ as a function of develop-
techniques to effectively change those specific factors. It is ment. For example, one developmental issue is that effect sizes
important to consider the possibility that CBT may not be of behavioral interventions may diminish as children age into
a fruitful path for adolescents with ADHD. Most disorders adolescence (Sanders, Kirby, Tellegen, & Day, 2014).
that can be treated effectively with CBT (e.g., anxiety, depres- Although it is unlikely that behavioral principles become less
sion) involve individuals who think too much (e.g., ruminating, relevant as children age, it is possible that the ability of an adult
worry) and their thinking is thought to affect their emotions and to adequately manage the complexities of reinforcement and
behavior (Beck, Rush, Shaw, & Emery, 1979). Conversely, punishment that operate in the life of a 15-year-old adolescent
adolescents with ADHD tend to not think enough before acting is far less than an adult’s ability to manage these in the life of
(i.e., impulsivity) and there are questions about the degree with a 5-year-old. The complex web of contingencies in the envir-
which their thoughts adequately shape their behavior. Thus, onment of adolescents means that parents and teachers are
changing the nature of their thoughts may not effectively competing with numerous other sources of reinforcement and
translate to behavior change. punishment (e.g., peer attention, social reputation issues, vari-
ety of achievement goals). Understanding not only the beha-
Training Interventions vioral mechanisms of action, but also those associated with
Training interventions have emerged as an alternative to cognitive and training interventions across development are
behavior therapy for youth with ADHD. Training interventions likely to lead the field to new and innovative approaches to
begin with brief psychoeducation about a target skill (e.g., treatment.
materials organization) and the majority of the time after that
is spent with extensive practice and performance feedback. It
Recommendation 3: Design Intervention Research
has been recommended that for training to be effective, the skill
Informed by a Life Course Model
must be directly applicable to an area of impairment, and
practice with performance feedback must occur frequently Research clearly indicates that ADHD is a chronic condition.
and over an extended period of time (Evans et al., 2018). A childhood diagnosis of ADHD places individuals at risk for
Studies with children (Abikoff et al., 2013) and young adoles- deleterious outcomes in adulthood, regardless of their ADHD
cents (Langberg et al., 2012) with ADHD indicate that training diagnostic status later in life (Hechtman et al., 2016).
and behavioral interventions have similar short-term benefits, Furthermore, the Multimodal Treatment Study of ADHD
but there is evidence unique to training interventions that their (MTA) found that beneficial effects of behavioral and
INTERVENTIONS FOR ADHD 139

medication treatment for ADHD implemented during child- Future research should focus on how progress monitoring
hood were not maintained into adolescence and young adult- data can be used to inform decisions about moving up and
hood (Molina et al., 2009). To address the chronic nature of down a tiered (layered) model of service delivery. Using popu-
ADHD, the need for sustained monitoring of outcomes over lation-based data, benchmarks indicating the probability of
time, the changing presentation of the condition and associated achieving positive outcomes at each tier could be proposed
risks over the course of development, and the need for inter- and evaluated. Further, adaptive or sequential multiple assign-
vention at various points during development (illustrated in the ment randomized trials (SMART) designs (e.g., Pelham et al.,
case of James), our team has espoused a life course model of 2016) could be used to test sequences of tiered interventions
care. This model is complementary with key elements of the and movement to different tiers of care based on response to
chronic care model, which has been recommended as intervention and attainment of benchmarks. Such research may
a framework for the management of ADHD (American be particularly important during transitions in schooling such as
Academy of Pediatrics [AAP], 2019; Van Cleave & Leslie, entry into elementary, promotion to middle or high school, and
2008). Three components of the chronic care model are espe- transition from high school to early adulthood.
cially relevant for ADHD intervention development: (1) sys-
tems to support population-based care; (2) strategies to Research in Health Systems. Similar to schools,
facilitate alliances across systems; and (3) strategies to promote a body of research has emerged supporting the use of
self-management of one’s own condition. a population-based approach for the care of individuals with
chronic illnesses (e.g., asthma, diabetes) or at risk for poor
health outcomes in the context of health systems.
Systems to Support Population-Based Care
Unfortunately, there has been a striking lack of research to
Historically, care for children with ADHD has been guide the application of this approach related to pediatric
conceptualized at the individual level; services are provided behavioral health conditions in health systems, including pri-
to one child at a time in a reactive manner by responding to mary care. Additional research is needed to identify the ele-
problems when they emerge (see the case of James). In ments of an approach targeting all children and adolescents
contrast, a population-based approach examines the popu- with ADHD in primary care. For example, electronic systems
lation of children served by an agency or organization (e.g., are being developed to support the assessment of ADHD and
school district, primary care network), and tracks outcomes monitoring of outcomes (Epstein et al., 2011), but we have
for all individuals in the population over an extended per- much to learn about how data in the electronic health record
iod of time. A population-based approach creates opportu- (EHR) can be used (e.g., through registries) to support universal
nities for proactive involvement with children who are care for children with ADHD and decision making to move to
identified as being at risk. Services are provided in the higher tiers of care when needed.
context of a multi-tiered or multi-layered system of care
to provide the right level of care in the most efficient
Strategies to Facilitate Alliances across Systems
manner.
Services for children and adolescents with ADHD are
Research in Schools. A considerable body of research offered in several settings, especially schools, primary care
has been conducted in schools to examine how a population- practices, and mental health agencies (public and private).
based approach can be applied. In some school systems, all Unfortunately, service delivery is fragmented and there is
students are tracked with regard to reading and math perfor- poor coordination across systems of care, often resulting in
mance, and behavioral functioning. Indices of behavioral func- parents being placed in the challenging position of linking
tioning might include suspensions, office discipline referrals, systems (Guevara et al., 2005), as was the case for James.
and frequent ratings of behavior by teachers using brief check- At least three approaches have been attempted to facilitate
lists (Christ, Riley-Tillman, & Chafouleas, 2009). Data from alliances across systems. One approach has been to use
these tracking methods are used to determine whether: (a) the electronic information systems to assess ADHD symptoms
child can be supported using evidence-based strategies that can and impairments and monitor outcomes; assess parent-
be readily implemented to the entire classroom (Tier 1); (b) reported goals for treatment and monitor goal attainment;
additional support may be required using brief, but individua- and share information across systems of care (i.e., families,
lized evidence-based practices (Tier 2); or (c) more intensive schools, primary care practices; Power et al., 2016).
evidence-based approaches are needed, which in some cases Because electronic information systems have the potential
might require special education resources (Tier 3; Sugai & to be provided to a large portion of the population of
Horner, 2006). Unfortunately, there is very little research on individuals with ADHD, they have been proposed as part
how to translate assessment results into choice of interventions of universal approaches to care (Power, Mautone, Blum,
or even tiers of interventions. Fiks, & Guevara, 2019).
140 DUPAUL ET AL.

Another approach is to enlist patient navigators to pro- how to promote their empowerment in managing ADHD.
mote collaborations among systems of care. This approach There are exciting opportunities to develop programs to
has been proposed as a Tier 2 strategy for families and promote youth empowerment to manage ADHD across
providers who need an intermediate level of support (Power the developmental span from elementary school through
et al., 2019). To date, there has been minimal research on secondary school and into early adulthood.
the use of care managers to support care for children with
ADHD and critical components of the role of these
providers. RECOMMENDATIONS FOR FUTURE RESEARCH
A third approach, proposed as a Tier 3 strategy, is to IN IMPLEMENTATION AND DISSEMINATION
embed evidence-based interventions in the context of inte-
grated methods of service delivery in primary care (Kolko The four evidence-based treatment reviews for ADHD (Evans,
et al., 2014). Integrated primary care offers a mechanism to Owens, & Bunford, 2014; Evans et al., 2018; Pelham &
promote collaboration between pediatric providers and Fabiano, 2008; Pelham et al., 1998) that cover over 60 years’
mental health professionals in the delivery of evidence- worth of research reveal a striking imbalance toward efficacy
based psychosocial and pharmacological interventions. studies relative to effectiveness studies. In the last review, less
A limitation is that this approach typically does not pro- than 10% of studies evaluated treatments implemented by
mote connections with schools, although models of inte- practitioners (i.e., non-research staff). Although efficacy studies
grated care have been adapted to link families, schools, and have been critical to the identification of evidence-based treat-
pediatric providers (Power et al., 2014). There are many ment (EBTs), with so few effectiveness trials, the next genera-
challenges to research related to this work including the tion of research should prioritize studying EBTs under
feasibility and acceptability of these approaches. For exam- authentic conditions (e.g., with referred rather than recruited
ple, there is evidence that the value of integrating services cases, implemented by practitioners rather than research staff).
may not be widely shared across professional groups. One Implementation research is the scientific study of methods to
study reporting an attempt at integrating teachers’ ratings of promote the systematic adoption of research findings and evi-
children’s behavior into the medication decisions of psy- dence-based practices into routine practice, with the goal of
chiatrists reported extreme difficulties getting teachers to improving the quality of care (Eccles & Mittman, 2006). One
complete ratings and even when ratings were collected, example of implementation research involves hybrid effective-
psychiatrists rarely considered the teacher data when mak- ness-implementation trials wherein both implementation and
ing decisions regarding medication treatment (Pliszka et al., treatment outcomes are evaluated simultaneously (Landes,
2003). This is just one example of the substantial research McBain, & Curran, 2019). In a hybrid design, researchers can
challenges that need to be addressed when pursuing the (1) test the effects of a clinical intervention on relevant out-
goal of an integrated approach to primary care. comes while gathering information on implementation; (2)
simultaneously test a clinical intervention and an implementa-
Strategies to Promote Self-Management tion strategy; or (3) test an implementation strategy while
Parents have a high level of responsibility for the man- gathering information of a clinical intervention’s impact on
agement of ADHD, especially when children are young. child outcomes. We recommend that the field focus on imple-
Parents can benefit from psychoeducation (Ferrin et al., mentation science approaches, including hybrid designs, to
2014), as well as strategies to promote readiness for change study EBTs under authentic conditions to enhance the state of
and motivation to pursue services (Nock & Kazdin, 2005). the science related to EBTs for ADHD in three critical areas:
Although the major focus of efforts to promote parental access, implementation fidelity, and cost-effectiveness.
empowerment has been on parents of young children with
this condition, it is important to address parents’ ongoing
Recommendation 4: Develop and Evaluate Strategies
needs for psychoeducation and motivational support, parti-
that Promote Treatment Access
cularly during periods when their children are struggling
and resources seem to be lacking. In addition to targeting As described previously, despite strong evidence distinguishing
parents, starting in the upper elementary years, and cer- EBTs from other practices, most children coping with ADHD
tainly by middle school, youth with ADHD are capable of lack access to evidence-based psychosocial treatment
assuming some responsibility for the management of their (Danielson et al., 2018; DuPaul et al., 2019). In order to have
condition. It is important for them to become aware of their EBTs make a significant impact on the nearly 7 million youth
limitations in paying attention and regulating their beha- struggling with ADHD, the next generation of research must
viors and emotions, their need for academic and social develop and evaluate strategies for ensuring that EBTs reach
support, and evidence-based strategies to assist them. In the majority of those affected by the disorder.
spite of the importance of youth with ADHD to learn how One mechanism that can be leveraged to enhance access
to manage their own care, there is very little research on to EBTs is technology. There are several examples where
INTERVENTIONS FOR ADHD 141

technology has been pilot tested as a means to enhancing more rigorous trials of this and other technologies are
access to care in primary care offices and schools, yet needed including study of applications to secondary school
additional work is needed. For example, there is emerging students.
evidence that technology, such as electronic health records
(EHR) with templates specific to ADHD and with remin- Recommendation 5: Identify Strategies to Optimize
ders for quality care actions can increase the likelihood of Implementation Fidelity
assessment of ADHD and quality documentation of that
assessment (e.g., Johnson et al., 2010). Also as discussed Despite the presence of clearly delineated manuals and
previously, electronic systems have been developed to guidelines for implementation of EBTs for ADHD, many
facilitate cross-setting (i.e., primary care offices, schools, providers are not trained in EBTs and the fidelity with
and home) communication to enhance access to evidence- which treatments are implemented is known to degrade
based assessment and treatment practices (e.g., Epstein when implementation supports and/or accountability are
et al., 2011). A promising system embedded in the EHR reduced (e.g., Noell et al., 1997). Thus, if EBTs are not
is the ADHD Care Assistant (see Power et al., 2016) which implemented with high fidelity (as was the case for James),
was designed to promote (a) shared decision-making there is likely little chance that they will impact desired
between family and provider by identifying family goals youth outcomes (e.g., Owens et al., 2018) and ultimately
and preferences for treatment (Fiks et al., 2012) and asses- little value in improving access. Thus, two top priorities for
sing goal attainment; and (b) the sharing of information future research in the area of enhancing intervention fidelity
among parents, educators, and health providers (Michel are the identification of mechanisms for (a) efficient and
et al., 2018). Expanded development and evaluation of effective training of those who can provide EBTs for
electronic systems such as the ADHD Care Assistant in ADHD (e.g., teachers, mental health providers, PCPs) and
the context of pediatric primary care holds the promise of (b) holding clinicians and teachers accountable for high
facilitating access to screening, assessment, and early quality implementation.
detection of ADHD. Indeed, such a system may have sig- There are multiple viable approaches for enhancing training
nificantly changed the life course for James and his family. and accountability, and perhaps a combination of these
However, additional study is needed to overcome barriers approaches may be necessary. For example, there is emerging
to use (e.g., technology support, parent and teacher access evidence that influential peers within a given social network
to technology) with a specific focus on uptake and sustain- (e.g., teachers within a school, providers within an agency) may
ment. Additionally, there is a need for expansion of online be powerful facilitators of enhanced implementation outcomes
systems to include measures validated for diagnosis and (e.g., Atkins et al., 2008). Although not all specific to ADHD,
progress monitoring for preschool and adolescent popula- research is being conducted to determine how influential peers
tions to enhance access to quality assessment for these can be efficiently identified and how these influential leaders
populations. can be leveraged to enhance others’ knowledge, adoption, and
Technology is also being leveraged to enhance chil- implementation of EBTs (e.g., Cappella & Godfrey, 2019).
dren’s access to EBTs in schools. For example, using Given the chronic nature of ADHD, a particularly compelling
hybrid designs, Owens and colleagues (Mixon, Owens, line of research would be to examine how influential peers
Hustus, Serrano, & Holdaway, 2019; Owens et al., 2019) could facilitate successful transition of students with ADHD
developed and evaluated the Daily Report Card.Online across grade levels and school settings.
(DRC.O) system, an interactive online resource that facil- Second, a review of training strategies across disciplines
itates teachers’ knowledge, adoption, and implementation (Lyon, Stirman, Kerns, & Bruns, 2011) highlights the utility
of a daily report card (DRC) intervention. The DRC.O of several approaches (e.g., coaching, reminders, problem-
mirrors face-to-face consultation through professional based learning) over one-time training in shaping provider
development content (including video models) that teachers behavior. A critical next step in this research is to examine
can access at their own time and pace, as well as interactive the possible mechanisms of change responsible for the associa-
mobile-friendly features designed to support teachers as tion between training strategies and improvements in provider
they develop the DRC, monitor and graph student progress, behavior. By understanding the unique processes responsible
and modify the intervention over time. Two studies docu- for provider behavior change, we may be able to consider
ment that, with this technology and very minimal additional which strategies are unique or redundant so that complimentary
support, a meaningful portion of teachers (39% to 54%) can strategies could be combined to maximize outcomes. In addi-
adopt and implement at DRC with positive student out- tion, research is needed to examine how such training and
comes (Mixon et al., 2019; Owens et al., 2019). However, implementation supports can be made feasible and sustainable
these were open trials with small samples. Thus, additional by schools and health/mental health agencies.
142 DUPAUL ET AL.

Third, there is evidence that measurement feedback systems functioning than beginning treatment with a low dose of
provided to clinicians can enhance child outcomes (e.g., pharmacological intervention ($1,689). This study is the
Bickman, Kelley, Breda, de Andrade, & Riemer, 2011). first to examine treatment sequencing and offers support
However, this strategy is rarely used in agencies, health sys- for the proposed layers in the life course model. However,
tems, or schools. In addition to identifying methods to increase many more questions about cost remain. For example, from
the use of measurement feedback systems in key settings, it will a school perspective, administrators could benefit from
be important to study how the use of technology, influential knowing the relative cost-effectiveness of various universal
peers, effective training and feedback systems could be com- school-wide or classwide approaches in preventing the
bined to enhance implementation by teachers and clinicians. need for more intensive services, or the relative cost-
Lastly, another innovative mechanism for enhancing quality effectiveness of using classroom interventions versus
and desired child outcomes is via a pay-for-success contract. accommodations. School and clinic administrators also
Within such a contract, investors offer capital up front, inde- could benefit from knowing the relative cost-effectiveness
pendent evaluators are leveraged to assess the extent to which of various models (e.g., technology-driven, one-time train-
desired outcomes are achieved (e.g., cost savings are accrued ing, ongoing consultation) of professional development and
due to reduction in risk status), and for each success case implementation supports for teachers and clinicians.
achieved, the investors receive a return of the principal plus Further, to date, published research only reveals cost effec-
a financial benefit. The U.S. Department of Education has tiveness for elementary students; future studies are needed
launched several pay-for-success contract projects (https:// for preschool and adolescent populations, as treatments and
www2.ed.gov/about/inits/ed/pay-for-success/index.html), risk profiles differ from those for elementary school
some of which are demonstrating promise within rigorous students.
randomized designs (https://ssir.org/articles/entry/pay_for_suc
cess_is_working_in_utah). Similarly, health systems are imple-
menting this type of arrangement by focusing on value-based
payments through accountable care organizations (i.e., health CONCLUSIONS
practices receive lump sums based on patients served and
patient outcomes; Rawal & McCabe, 2016). Thus, the impact Given the chronicity of symptoms and impairment asso-
of pay-for-success contracts to optimize ADHD treatment fide- ciated with ADHD, it is critically important that effec-
lity in health and school settings is a potentially fruitful line for tive treatment strategies are implemented across home,
effectiveness research. school, and community settings to reduce symptoms
and, most importantly, enhance educational and social
functioning over time (see Figure 1). Although multiple
psychosocial intervention approaches have been found
Recommendation 6: Examine and Optimize
efficacious in the context of controlled investigations,
Cost-Effectiveness
these treatments often are not implemented with suffi-
As early as the 1998 review (Pelham et al., 1998), research- cient fidelity and/or consistently across systems and
ers were recommending analyses to reveal the relative costs time in community and school settings, as was demon-
and cost effectiveness of behavioral as compared to phar- strated by the case of James. Using a life course model
macological treatments. In the ensuing decade, studies as context, we propose six research directions to
examined the cost-effectiveness of medication management address major challenges to treatment development,
and behavioral intervention as prescribed in the Multi- evaluation, implementation, and dissemination.
modal Treatment Study for ADHD (Foster et al., 2007; Priorities for psychosocial treatment development and
Jensen et al., 2001). These studies provided important evaluation are to identify and leverage mechanisms of
advancements in our knowledge of cost; however, costs change, examine and address the impact of child devel-
were estimated using treatments provided in the MTA opmental status on treatment mechanisms and out-
study, which are not replicable and not available in most comes, and design intervention research informed by
communities. a life course model. Treatment implementation and dis-
Addressing this limitation (i.e., using less intensive semination investigations should leverage implementa-
treatment protocols), Page et al. (2016) examined the rela- tion science methods to develop and evaluate strategies
tive cost effectiveness of behavioral, pharmacological, and that promote access to evidence-based treatment, opti-
combined interventions employed in a sequential, adaptive mize treatment fidelity in community and school set-
trial investigating the sequencing and enhancement of treat- tings, and optimize costs and cost-effectiveness of
ment for children with ADHD (Pelham et al., 2016). psychosocial interventions.
Findings suggest that starting with a low dose behavioral To support this work, investigators should consider
intervention was less costly ($961) for one year of treat- funding mechanisms such as Clinical Trials to Test the
ment and more effective in changing impairment in Effectiveness of Treatment Preventive, and Services
INTERVENTIONS FOR ADHD 143

Interventions offered by the National Institute of Mental Boyer, B. E., Geurts, H. M., Prins, P. J. M., & Van Der Oord, S. (2015).
Health (https://grants.nih.gov/grants/guide/rfa-files/RFA- Two novel CBTs for adolescents with ADHD: The value of planning
skills. European Child & Adolescent Psychiatry, 24, 1075–1090.
MH-18-701.html) that are designed to support trials that
doi:10.1007/s00787-014-0661-5
examine effectiveness of interventions and possible Cappella, E., & Godfrey, E. B. (2019). New perspectives on the child-and
mechanisms of action. Alternative sources of funding that youth-serving workforce in low-resource communities: Fostering best
place a priority on effectiveness and implementation practices and professional development. American Journal of
research are the Institute of Education Sciences and the Community Psychology, 63, 245–252. doi:10.1002/ajcp.12337
Patient-Centered Outcomes Research Institute. Our field Carper, M. M., Makover, H. B., & Kendall, P. C. (2018). Future directions
needs to go beyond short-term, efficacy trials to reduce for the examination of mediators of treatment outcomes in youth.
Journal of Clinical Child & Adolescent Psychology, 47, 345–356.
ADHD symptoms conducted under ideal controlled condi-
doi:10.1080/15374416.2017.1359786
tions and successfully address the research-to-practice gap Chacko, A., Wymbs, B. T., Flammer-Rivera, L. M., Pelham, W. E.,
by advancing development, evaluation, implementation, Walker, K. S., Arnold, F. W., & Herbst, L. (2008). A pilot study of
and dissemination of evidence-based treatment strategies the feasibility and efficacy of the Strategies to Enhance Positive
to ameliorate functional impairment that can be used with Parenting (STEPP) program for single mothers of children with
ADHD. Journal of Attention Disorders, 12, 270–280. doi:10.1177/
fidelity by parents, teachers, and community health provi- 1087054707306119
ders. By focusing research in these directions, we can Chorozoglou, M., Smith, E., Koerting, J., Thompson, M. J., Sayal, K., &
substantially improve outcomes for youth with ADHD Sonuga-Barke, E. J. S. (2015). Preschool hyperactivity is associated
like James. with long-term economic burden: Evidence from a longitudinal health
economic analysis of costs incurred across childhood, adolescence and
young adulthood. Journal of Child Psychology and Psychiatry, 56,
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Christ, T. J., Riley-Tillman, C. T., & Chafouleas, S. M. (2009). Foundation
No potential conflict of interest was reported by the for the development and ese of direct behavior rating (DBR) to assess
authors. and evaluate student behavior. Assessment for Effective Intervention, 34
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