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DADEX ANTIMICROBIAL PIPES Antimicrobial Pipes Lia fon a) Ca FOR POTABLE WATER SUPPLY SYSTEMS * Built-in Antimicrobial Protection against Bacteria, Fungi and Algae. * Maximum protection against water borne diseases and bio-film development. = 99.99% Antimicrobial efficacy against microorganisms. = Improves water quality and prevents the development of bad tastes and colors in water. ® ® a DADEX reesos Pekin Sugars OVER 55 YEARS OF EXCELLENCE ee Antimicrobial Pipes Dadex Antimicrobial Pipes Dadex is committed to water conservation as well as the supply of sofe water for health and well-being of our people. To this purpose, Dadex has once again brought « revolutionary technology for the first time in the piping industry of Pakistan, by introducing antimicrobial pipes containing state of the art antimicrobial technology, developed by o UK based company having its network in 98 countries. Dadex Antimicrobial pipes are available in PPR Polydex Pipes, PVC Pressure Pipes and PE Water Pipes used for potable water supply systems. Dadex antimicrobial pipes have 99.99% antimicrobial efficacy and provide long lasting protection against Bacteria, Fungi and Algae; hence providing safe and healthy water. The Need for Antimicrobial Pipes Pipes ore the backbone of water distribution systems in building and infra-structure, and once incorporated, lasts os long os the life span of the structure. Water distribution systems provide 0 suitable milieu for micro-organisms: Bacteria, Fungi and Algae. Microbes which survive in the distribution system possess the abilily to grow and produce BIOFILM, a surface deposit of microorganisms, and organic and inorganic materials that accumulate within a slime layer. Biofilms induce many problems in water distribution systems like: change in color, odor, taste and turbidity of water, blockage of pipes and inefficacy of disinfection treatment. The slimy layer of biofilm act as a slow-release mechanism for persistent contamination of water. The microbial contamination and buildup in water distribution pipes pose a direct risk to public health because of water-borne diseases. Most common diseases, due to microorganisms, associated with water contamination are Pseudomonas, Aeromonas, Klebsiella, E.coli, Helicobacter, Vibrio spp. Shigella, Salmonella, Leaionella spp. Asoeraillus, Cryptococcus and Mucor, These pathogens can cause serious illnesses like diarrhea, dysentery, gastroenteritis, allergies, skin infection, etc. Water-borne diseases pose serious threat to public health: © According to WHO (2014), every year more than 3.4 million people die as a result of water- reloted diseoses, making it the leading cause of morbidity and mortality around the world © 1.8 million people die every year from diarrheal diseases. 90% are children under 5, mostly in developing countries. © 88% of diorrheal diseases are attributed to unsafe water supply, inadequate sanitation and hygiene (WHO). © Elderly people, children, people with weak immune system and pregnant women are more susceptible to water borne diseases. ee Antimicrobial Pipes How Microbes Enter into Distribution Pipes © Water in the supply pipes is not sterile, regardless of the degree to which the water is treated © Microbes can enter the distribution pipes via a voriety of pathways and become entrained in the biofilm for later release, such as, leakage in pipes, valves, joints and seals, untreated ground water, improper storage tanks/vessels, cross connections and during maintenance and repair. © Biofilms invariably develop in all Drinking Water Distribution Systems (DWDSs}, despite the presence of residual disinfectant, Dadex has made the piping system microbe-free by incorporating antimicrobial technology. As bacteria lands on the inner pipe wall, antimicrobial technology eliminates the bacteria and supports to provide safe water. Dadex antimicrobial pipes eradicate the bacteria in pipe surfaces and protect against the development of microbial biofilm in water distribution systems. The built-in antimicrobial technology becomes an integral port of the finished product. The antimicrobial additive being used by Dadex in antimicrobial pipes has been tested against over 50 dangerous microorganisms including: MRSA, E. coli Salmonella, Klebsiella pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa, Clostridium difficile, A. niger Corynebacterium spp, Escherichia coli. The Dadex antimicrobial products have built-in anti-fungal, anti-bacterial, anti-mold, anti-mildew and anti-algal protection, providing a broad spectrum of total antimicrobial performance. Features of Dadex Antimicrobial Pipes * Built-in Antimicrobial Protection against Bacteria, Fungi and Algae. © Dadex antimicrobial pipes are tested by Intertek for antimicrobial performance. © Maximum protection against water borne diseases and bio-film development. = 99.99% antimicrobial efficacy against microorganisms. ‘© Effective and long-lasting antimicrobial protection that keeps the pipe sofe from bacteria and provides healthy water. * Improves water quality and prevents the development of bad tastes and odors in water. ee Antimicrobial Pipes How Dadex Antimicrobial Pipes works? The antimicrobial technology provides effective and broad spectrum antimicrobial performance Antimicrobial Process - 3 Stages International Standards Compliance The Dadex antimicrobial pipes conforms to the following standards for its antimicrobial efficacy. Antifungal testing —_1S016869:2008, ASTM G21-09 and ASTM E 2180 Anti-bacterial testing SO 22196:2011 and JIS Z 2801 Anti-algae testing ASTM D 5589-09 and prEN WD algae Antimicrobial Pipes Antibacterial Efficiency - Test Results Broad spectrum anti-bacterial efficacy of Dadex antimicrobial pipe samples was evaluated by following ISO 22196 standard procedure against Gram Positive and Gram Negotive Bacteria. Following results clearly indicate 99.99 % antibacterial performance of Dadex uPVC, PPR and HDPE antimicrobial pipes. Antifungal Efficiency - Test Results Antifungal testing is carried out according to ASTM G21, a qualitative testing method from Intertek. Asscale from 0-4 growth and 4 means more than 60% fungal growth on test sample. used to indicate fungal growth on treated and controlled samples. 0 means no Following results clearly indicate excellent antimicrobial performance of Dadex uPVC, PPR and HDPE antimicrobial pipes. ee Antimicrobial Pipes Dadex HDPE Pipe Results : Name of Test Bacteria Staphylococcus aureus] Escherichia Colo (Strain Number) (ATCC 6538P) (ATCC 8739) Concentration of inoculum 1.27 x 10° CFU/ml 6.35 x 10° CFU/ml ‘Average of the number of viable cells of bacteria 1.11 x10'CFU/em? | 1.72% 10" CFU/em* immediately after inoculation on the control sample (U,) 1Log : 4.05 Mog : 4.24 ‘Average of the number of viable cells of bacteria on the control | 3.75x10°CFU/em* | 4.94% 10°CFU/om* saitiple after 24 hours (W) 10g: 0.57 /Log :6.68 Average of the number of viable cells ot bacteria on <0.63 CFU/em* (#) +<0.63 CFU/cm* (#) the antimicrobial test piece after 24 hours (A) Mog: ~ Mog :~ Value of antimicrobial activity (R) Log :>5.94 Log: >6.06 Calculation : R = Log U,-Log A, Remark: CFU = Colony forming uni Less than < = Morethan # = When the number of viable bacteria : A” is less than 0.63, it shall be taken as :"A,” and the average of logarithm numbers shall be calculated. Dadex PPR Pipes (Polydex) Results : Name of Test Dacteria ‘Stephylococcus aureus] Cacherichia Golo (Strain Number) (ATCC 6538P) (ATCC 8739) Concentration of inoculum 2.7 «10° CFU/ml 7.15 10° CFU/ml Average of the number of viable cells of bacteria 9.88 x 10° CFU/cm* 1.03 x 10° CFU/em* immediately after inoculation on the control sample (U,) /Log : 3.99 /Log: 4.01 Average of the number of viable cells of bacteria on the control 2.03 x 10° CFU/em* 2.85 x 10° CFU/em* sample after 24 hours (U) /Log: 5.31 (Log : 5.45 ‘Average of the number of viable cells of bacteria on <0.63 CFU/em* <0.63 CFU/em’) the antimicrobial test piece after 24 hours (A) /Log: 0.63 Nog : 0.63 Value of antimicrobial activity (R) Log:> 4.68, Log: > 482 Calculation : R = Log U,- Log A, Remark: CFU = Colony forming uni rs Antimicrobial Dadex uPVC Pressure Pipe Results : ‘Name of Test Bacteria ‘Staphylococcus aureus (Strain Number) (ATCC 6538P) (aTec 8739) Concentration of inoculum 2.7 x10" CFU/ml 7.15 x 10° CFU/ml ‘Average of the number of viable cells of bacteria 9.88 x10 CFU/em? | 1.03x 10° CFU/em* immediately after inoculation on the control sample (U,) /Log: 3.99 7Log: 4.01 Average of the number of viable cells of bacteria on the control | 2.03x10°CFU/cm’ | 2.85x10°CFU/cm* sample after 24 hours (U) /Log :8.31 Mog: 5.48, ‘Average of the number of viable cells of bacteria on. <0.63 CFU/om* <0.63 CFU/om* the antimicrobial test piece after 24 hours (A) /Log : 0.63 Log : 0.63 Value of antimicrobial activity (R) Log: > 4.68 Log: > 4.82 Calculation : R = Log U,- Log A, Remark: CFU = Colony forming uni rationTest Standard Results ‘Samples submitted as per applicant's request with reference to European Commission Regulation No. 10/2011 Overall Migration TeSt oun — Pass Specific Migration of Heavy Metal Test Pass Specific Migration of Primary Aromatic Amines Test......PaSs Test For F.D.A. Regulation on Polyethylene. son PASS: ~As Per U.S. 21 CFR Part 177.1520 Clauses (c)(2.1) and (d) Migration Test Conditions Test Item1. Overall Migration Test 40°C? for 10 Days Food Simulant —— 3% Acetic Acid Test Item2. Specific Migration Test (Heavy Metals) Condition 50°C? for 10 Days Food Simulant —— 3% Acetic Acid Test Item3. Specific Migration Test (Primary Aromatic Amines) 50°C? for 10 Days Food Condition wulant —— 3% Acetic Acid ee Antimicrobial Pipes * Islamabad : UAN : (92-51) 111 000 789, 4861034-7, Fax : (92-51) 4861033 E-mail : islamabod@dadex.com.pk * Lahore : UAN : (92-42) 111 000 789, 35760735-6, Fox : (92-42) 35760734 E-mail : lahore@dadex.com.pk * Multan : Tel : (92-61) 4545259, Fox : (92-61) 4784688 E-mail : multan@dadex.com.pk * Faisalabad : Tel : (92-41) 8861981, 8787944, Fax : (92-41) 8787944 E-mail : faisolabod@dadex.com.pk * Peshawar : Tel : (92-91) 5840316-7, Fux : (92-91) 5840317 E-mail : peshawor@dadex.com. pk * Quetta : Tel : (92-333 7845732) E-mail: quetio@dadex.com.pk bbe used. lease ensure compliance with ali health and salely requirements. Whilst contnuing is programme of continuous development, Seller reserves the right te modify oF ‘stor any pubihed iformation without ary pie notation. No respons ean be scapted or any err omissions r erect sumptions ‘Sele’ esponsiiinesponsiy of aller cates once the god ae dlnered pilerage, shot 3 efor any ‘Soangrénal damage incsing bunt ted econo a of ty ile hater spon he products big vere othe sl pte treo is Cae. ‘ny dao esponsty a state herein wl at be entertained by the Sele and such so il als hot be te cause of Spat bythe buyer” ayer represnttine ar cn, where deliver ikem in peso In oe cates DADEX Eternit Limited Dadex House : 34-A/1, Block-6, P.E.C.H.S, Shahrah-e-Faisal, Karachi, Pakistan. Tel. # (92-21) 111 000 789, Fax # (92-21) 34313881, 34315716 E-mail nfo@ dadex.com Web : www

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