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CLINICAL
Article REHABILITATION
Clinical Rehabilitation
Abstract
Objective: To investigate the effects of the CORE programme on pain at rest, movement-induced pain,
secondary pain, active range of motion, and proprioception deficits in female office workers with chronic
low back pain.
Design: Randomized controlled trial.
Setting: Rehabilitation clinics.
Subjects: A total of 53 participants with chronic low back pain were randomized into the CORE group
and the control group.
Intervention: CORE group participants underwent the 30-minute CORE programme, five times per
week, for eight weeks, with additional use of hot-packs and transcutaneous electrical nerve stimulation,
while the control group used only hot-packs and transcutaneous electrical nerve stimulation.
Main measures: Participants were evaluated pretest, posttest, and two months after the intervention
period to measure resting and movement-induced pain, pressure pain as secondary pain, active range of
pain-free motion, and trunk proprioception.
Results: Pain intensity at rest (35.6 ±5.9 mm) and during movement (39.4 ±9.1 mm) was significantly
decreased in the CORE group following intervention compared with the control group. There were
significant improvements in pressure pain thresholds (quadratus lumborum: 2.2 ±0.7 kg/cm2; sacroiliac joint:
2.0 ±0.7 kg/cm2), active range of motion (flexion: 30.8 ±14.3°; extension: 6.6 ±2.5°), and proprioception
(20° flexion: 4.3 ±2.4°; 10° extension: 3.1 ±2.0°) in the CORE group following intervention (all p < 0.05).
1The Post-Professional DPT Program, The Richard Stockton *Two authors are equally contributed to this study.
College of New Jersey, Galloway, NJ, USA
2Department of Physical Therapy, Korea University, Seoul, Corresponding author:
South Korea Hwi-young Cho, Department of Physical Therapy, College
3Department of Physical Therapy, Gachon University, Incheon, of Health Science, Gachon University, 191 Hambangmoe-ro,
South Korea Yeonsu-gu, Incheon, 406-799, Republic of Korea.
Email: hwiyoung@gachon.ac.kr
These improvements were maintained at the two-month follow-up. The control group did not show
significant improvements in any measured parameter.
Conclusion: The CORE programme is an effective intervention for reducing pain at rest and movement-
induced pain, and for improving the active range of motion and trunk proprioception in female office
workers with chronic low back pain.
Keywords
Movement-induced pain, CORE programme, chronic low back pain, proprioception, active range of
motion
Introduction
Low back pain is the most common disorder in programme that controls tension of the lumbar–
modern society.1 Female office workers, in particu- pelvis–hip joint to strengthen muscles, increase
lar, have a higher risk of developing chronic low endurance, and improve posture. This programme
back pain.2 can also be easily performed and has low direct
Chronic low back pain patients tend to minimize costs and low risk of injury.10 However, the effect
trunk movement to alleviate lumbar pain, which, in of the CORE programme on pain, active range of
turn, aggravates lumbar muscle weakness of the par- motion, and proprioceptive acuity in female office
aspinal and multifidus muscles.3 In addition to mus- workers remains unclear. To our knowledge, most
cular inhibition, patients who experience chronic previous studies relating to chronic low back pain
low back pain demonstrate impaired proprioception, have only assessed pain at rest, although most
which is the sense of position and movement of the patients suffer from pain during daily activities.11
human body, and this impairment causes motion Therefore, evaluating movement-induced pain is
error and motor function deficit.4 Owing to these important.
functional deficits, chronic low back pain patients Thus, the purpose of this study was to identify
show altered muscle recruitment patterns and differ- the effects of the CORE programme on pain at rest,
ences in motor control, such as delayed reflex movement-induced and secondary pain, active
latency and poor postural control.5,6 Consequently, range of motion, and proprioceptive acuity in
improvements in muscle strength and propriocep- female office workers with chronic low back pain.
tion are novel therapeutic goals of chronic low back
pain rehabilitative programmes. Although some sys-
tematic reviews have reported the effects of various Materials and methods
core stability exercises on low back pain in the past
Participants
decade, there is currently a growing interest in the
ability of these exercises to change certain aspects of This study is a single-blinded, randomized con-
physical function, such as muscle strength, mobility, trolled trial with three measurement time points:
and muscular endurance.7,8 baseline (pretest), after eight weeks (posttest), and
A variety of exercise programmes have been two months following completion of the exercise
recommended to facilitate chronic low back pain programme (follow-up). Between March and
patients to actively enhance lumbar stability, using December 2011, female office workers presenting
exercises that strengthen muscle control and move- with non-specific chronic low back pain at the par-
ment.9 The CORE programme, suggested by Brill ticipating rehabilitation clinics located in Seoul,
and Couzens,10 is a lumbar stabilization exercise South Korea were recruited. They underwent an
interview to record their medical history and a isometric movement of core muscles, including
physical examination by a blinded assessor. The internal/external oblique, transversus abdominis,
inclusion criteria were as follows: (1) 20–40 years lumbar multifidus, rectus abdominis, and erector
of age, (2) non-specific chronic low back pain for spinae muscles. Participants were instructed to
more than three months, and (3) ability to move carry out slow and controlled movements, to pay
without assistance. Patients with any history of spi- attention to their breathing as they started each
nal or lower limb surgery, structural spinal abnor- exercise, and to keep breathing during each exer-
mality, signs of nerve compression, pregnant status, cise. Participants in the CORE group were required
or severe musculoskeletal disability were excluded. to carry out the exercises at home on a daily basis
In addition, participants included in the study did and to record their participation in a daily log to
not engage in regular exercise prior to the interven- monitor compliance. For the full programme, daily
tion. All experimental procedures were conducted practice was calculated as the proportion between
in accordance with guidelines set by the local the self-reported mean time and the prescribed time
research ethics committee. Sample size was calcu- of exercise in a day to know the compliance rate.
lated using G-Power version 3.1.3 (Informer Additionally, the same two physical therapists
Technologies, Dusseldorf, Germany). The effect monitored patient progress during rehabilitation
size was set at 0.90, the α error at a probability of centre visits and made weekly phone calls to moti-
0.05, and the power at 0.85. A minimum of 24 par- vate patients to continue with the CORE pro-
ticipants was required in each group. gramme. After eight weeks of the programme, all
participants were asked to completely stop the
exercises. Participants who received other medical
Experimental procedures and intervention, those who had personal issues that
interventions might interfere with the study protocol, and those
All participants were randomly assigned to the who had not regularly performed the CORE pro-
CORE group or the control group using random gramme exercises were excluded from the study at
allocation software, by an independent examiner this stage. The purpose and process of the experi-
who was not involved in participant recruitment.12 ment were explained to the participants, and they
The participants allocated to the CORE group per- voluntarily signed the informed consent form.
formed the CORE exercises for 30 minutes, five
times per week, for eight weeks, in addition to the
Outcome measurements
standard treatment of 20 minute transcutaneous
electrical nerve stimulation and 15 minute hot-pack General characteristics, such as age, height, weight,
treatment, while the control group received only and duration of symptoms were assessed using a
the standard treatment. survey method. The participants’ visual analogue
Details of the eight-week CORE exercise pro- scales at rest and during movement, pain pressure
gramme are described in Appendix 1, available threshold, active range of motion, and repositioning
online. To assure reliability of the intervention, two error were measured by the same blinded examiner
trained physical therapists instructed the partici- in order to reduce measurement error. All data were
pants how to perform the CORE programme exer- measured in the same place, both before and after
cises; they ensured that the CORE group performed intervention. All pretest, posttest, and follow-up
the exercises appropriately, with sufficient abdomi- outcome measurements were evaluated by the same
nal muscle contraction. The core concept of the examiner to ensure proper masking of patients.
programme is recruiting the abdominal muscles in To assess pain intensity at rest and during move-
the most effective way. The CORE programme ment, we used the 100-mm visual analogue scale.
exercises were divided into three categories (warm- Visual analogue scale at rest (resting pain) was
up, conditioning, and cool-down) and consisted of defined as an unpleasant feeling or pain when
14 exercises in total. The programme emphasized patients were still. Visual analogue scale during
movement (movement-induced pain) was defined target position. The absolute value of the deviation
as an unpleasant feeling or pain incurred by full- angle was measured three times and the mean value
flexion of the trunk.13,14 Patients marked their sub- was calculated.
jective pain intensity at rest and during movement
on a 100-mm visual analogue scale table.
Statistical analysis
Pain pressure threshold, a predictor of secondary
pain, namely chronic low back pain, was measured All statistics were performed using SPSS software
using a pressure algometer (NeuroDyneMedicaco version 15.0 (SPSS, Chicago, IL, USA). The
Corp., Cambridge, MA, USA).15 The purpose of the Shapiro–Wilk test was used to confirm the normal-
measurement was fully explained to participants. ity of the data. Repeated measure analysis of vari-
The algometer was placed perpendicular to the cho- ance was utilized to assess the visual analogue
sen lumbar sites. The examiner then applied pres- scale scores and pain pressure threshold values at
sure on the site at a consistent rate of 1 kg/s. The pretest, posttest, and follow-up time points. The
participant was asked to inform the examiner when Tukey multiple comparison test was used as a post-
an unpleasant feeling or pain started, and this meas- hoc test. The independent t-test was used to com-
urement was considered the pain pressure threshold. pare differences in dependent variables according
Two anatomical sites were used to measure pain to the used exercise manners between the two
pressure threshold: 5 cm lateral to the L3 spinous groups. The level of statistical significance was set
process (quadratus lumborum) and 5 cm lateral to at P < 0.05.
the L5 spinous process (sarcoiliac joint).16
The lumbar active range of motion was meas-
Results
ured using DUALER PLUS inclinometers (Angle/
Level, Dejon Tool Co., Covington, OH, USA) and A total of 80 patients were initially recruited, and
was calculated as the total angle of lumbosacral after the screening test, 74 eligible participants
flexion and extension. To measure active range of were enrolled in the study. The reasons for exclu-
motion, a single inclinometer was placed over the sion were pregnancy, declining attendance, and
L1–S2 spinous processes. The inclinometer’s sen- history of spinal operation. A total of 21 partici-
sor was zeroed when subjects were in a neutral pants were excluded at eight weeks (posttest),
position. The angle was recorded when the highest giving an attrition rate of more than 25%. The rea-
lumbar active range of motion was reached. This sons for exclusion were: receiving other medical
measurement was performed three times, and the interventions, personal issues, surgery, or preg-
mean value was recorded. nancy. Figure 1 demonstrates progress through
Proprioceptive acuity was assessed by measuring this study.
the active positioning ability of the lumbar region. The general characteristics of the patients are
We used the active angle reproduction method to shown in Table 1. There were no significant differ-
monitor active positioning ability.17 The patient ences in age, height, weight, or duration of chronic
flexed the trunk to a predetermined target position low back pain between the two groups. In the
and then attempted to replicate the position. The par- CORE group, the eight-week programme compli-
ticipant’s trunk was moved passively and randomly ance rate was 85.5%.
to target angles of 20° of trunk forward flexion and Comparisons between the groups following
10° of trunk extension. The trunk was held for intervention, using the independent t-test, demon-
10 seconds at the target angle and then returned to strated significant differences favouring the CORE
the starting position. After maintaining the starting group with regard to pain at rest and during move-
position for 10 seconds, participants attempted to ment, pressure pain threshold, active range of
replicate the target angles. Repositioning error was motion, and proprioception (all P < 0.001). In the
calculated as the absolute difference between the analysis of changes in measured parameters over
actual target position and the patients’ perceived time, using repeated-measure analysis of variance,
significant differences were seen in the CORE noted in the control group. These results are pre-
group regarding pain at rest (F = 141.487, sented in Table 2.
P < 0.001), pain during movement (F = 129.550, Table 3 shows the results of correlation analyses
P < 0.001), pressure pain threshold in the quadra- performed in the CORE group and the control
tus lumborum (F = 32.205, P < 0.001) and the sac- group. Using Pearson’s correlation coefficients,
roiliac joint (F = 23.029, P < 0.001), and active movement-induced pain was found to be most
range of motion of trunk flexion (F = 19.992, closely correlated with proprioception at 20° flex-
P < 0.001). There were no significant changes ion, and decrease in the active range of motion of
trunk flexion was most closely correlated with maintained three months after the use of stabiliza-
movement-induced pain. Active range of motion of tion exercise.20 Typically, patients learn to recruit
trunk extension and proprioception at 10° exten- deep spinal muscles by reducing undesirable hyper-
sion were closely correlated with pain on move- activity of other muscles during the performance of
ment (Table 3). specific stabilization exercises.21 Moreover, trunk
stability exercise programmes restore coordination
of the trunk muscles by improving the control of the
Discussion lumbar spine and pelvis.22 The CORE programme
In female office workers with chronic low back used in our study maintained lumbar stability by
pain, we found that the CORE programme effec- controlling tension of the lumbopelvic–hip joint
tively decreased pain at rest and movement-induced and also improved trunk coordination and posture.
and secondary pain. In addition, active range of These results are similar to the findings of the two
motion and proprioception improved after using aforementioned studies that showed that exercise
the programme. These effects were maintained for maintains pain reduction and motor function
two months following the intervention. These improvement from two months to two years by
results suggest that the CORE programme may increasing lumbar stability.
have positive effects on chronic low back pain in Compared with the control group, the CORE
female office workers. group showed significantly higher scores for the
Pain and loss of flexibility are the main symp- pressure pain threshold. This result is consistent
toms caused by chronic low back pain; therefore, with that of Kumar’s study, in which the increase in
these assessments are important indices for deter- the pressure pain threshold was statistically signifi-
mining treatment efficacy. Visual analogue scale cant after stabilization exercises had been carried
scores are used for measuring various parameters.18 out by patients with chronic low back pain.23 We
However, there is limited published evidence on hypothesize that an association exists between an
chronic low back pain available to guide research- increased pressure pain threshold and reduced back
ers or clinicians on how to separately determine muscle spasm. Back muscle spasm, from which
pain at rest and pain during movement. Accordingly, secondary pain originates, is a clinical feature of
our study separately measured both pain at rest and chronic low back pain.24 This phenomenon
movement-induced pain. Our results found that the increases sensitivity to mechanical stimuli.25 In
group carrying out CORE exercises showed a sig- addition, patients with chronic low back pain suffer
nificant decrease in both pain at rest and movement- from muscle weakness in the lumbar spine.26
induced pain compared with the control group. This According to the biomechanical model theory,
is similar to the results of previous studies. Goldby weak muscles cause mechanical irritation to the
et al. reported pain reduction in chronic low back lumbar spine, which stimulates pain-sensitive struc-
pain patients after 10 weeks of specific spinal stabi- tures, resulting in pain.27,28 Furthermore, continued
lization exercises.19 Koumantakis et al. also demon- stimulation of pain-sensitive structures is the main
strated significant low back pain reduction that was cause of maladaptive central sensitization and
Table 2. Changes in the visual analogue scale scores, pain pressure threshold, active range of motion, and
proprioception.
Table 3. Pearson correlation coefficients between movement-induced pain and active range of motion/
proprioception.
r p
VAS during movement vs. AROM at flexion −0.749 <0.001
VAS during movement vs. AROM at extension −0.548 <0.001
VAS during movement vs. proprioception at 20° flexion −0.833 <0.001
VAS during movement vs. proprioception at 10° extension −0.676 <0.001
chronic pain.29 The vicious cycle of muscular plays an important role in changes in trunk proprio-
spasms owing to pain, and intensification of the ception and that the alleviation of low back pain has
pain owing to these spasms, is the currently accepted a positive influence on proprioception.
mechanism of chronic low back pain.30 We believe As previous studies have stated, therapeutic
that the use of our CORE programme normalized exercises, such as core stabilization, spinal stabili-
the function of weak muscles, which, in turn, zation, or segmental stabilization exercise, have a
improved support and control of the spine and pel- positive effect on the reduction of low back
vis, thereby alleviating mechanical irritation, pain, pain.19,20,31–33 .However, it is difficult to directly
and muscle spasm in the low back region. compare our study with previous reports because
This study also measured lumbar active range of of differences in experimental design parameters,
motion and trunk proprioception. These outcomes including participant selection and age, causes or
in the CORE group improved significantly follow- duration of low back pain, outcome measurements,
ing intervention. This is similar to the result of intervention methods, sessions or duration of inter-
Lewis’ study in which the range of motion of vention, and the degree of baseline pain measured
patients with low back pain increased after the use in subjects. A randomized study by Lee et al.,32
of stabilization exercises for eight weeks.31 The which included similar subjects and used the same
results of this study were attributable to an increased intervention period and outcome measurements as
degree of spinal mobility caused by relieving lum- our study, found that 50 minutes of Pilates exercise
bar muscular tension through the CORE pro- for eight weeks (24 sessions) resulted in a decrease
gramme. As mentioned earlier, we believe that the of approximately 45% in low back pain in busi-
increase in the pressure pain threshold seen in nesswomen. Furthermore, You et al. found that
patients in the CORE group is owing to relief of 40 minutes of novel core stabilization exercises,
back muscle spasms, and the improvement in active performed three times per week, for eight week (24
range of motion is related to the reduction of pain. sessions), decreased low back pain by approxi-
In addition, when we determined the correlation mately 30%.33 However, unlike these previous
between movement-induced pain and active range studies, our 30-minute CORE programme, consist-
of motion at flexion and extension, we found a sig- ing of 40 sessions, decreased low back pain by
nificantly negative correlation (Table 3). These 63%. Based on this outcome, we suggest that an
results suggest that reduction of movement-induced increased number of sessions during the same
pain has an important role in improvement of active intervention period may have a greater beneficial
range of motion. We also found a negative correla- effect on reduction of low back pain than the exer-
tion between movement-induced pain and proprio- cise session duration.
ception (Table 3). These outcomes support the This study has certain limitations. First, we
results of previous studies in which patients with chose a group of relatively healthy young women
low back pain exhibited proprioceptive impair- who worked in offices. Second, the sample size
ment.4 Our results also indicate that low back pain was small. Therefore, our findings cannot be
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