1.

) Simethicone is a combination of fully methylated siloxane polymers, that is stabilized with

trimethylsiloxy end-blocking units, and silicon dioxide, or commonly known as silica gel. It is
composed of 90.5-99.0% polydimethylsiloxane, and 4.0-7.0% silicon dioxide. It is a viscous
liquid, that is insoluble in water and alcohol.

Silicon dioxide
polydimethylsiloxane  (silica gel)

Figure 1. Simethicone’s Chemical Structure

Source: newdruginfo.com
4.) 40 mg/mL = 4000 mg/ 100 mL
4000 mg = 4 g
% w/v = 4 g X 100%
100 mL
% w/v = 4% w/v, simethicone
REFERENCES

Simethicone. (2006, April 28). Retrieved November 14, 2020, from

https://pubchem.ncbi.nlm.nih.gov/compound/Simethicone

Simethicone. (n.d.). Retrieved November 14, 2020, from

http://www.newdruginfo.com/pharmacopeia/usp28/v28230/usp28nf23s0_m75400.htm