Solvent Miscibility Chart

Tetrahydrofuran (THF)
Dichloroethane (1,2-)
Carbon Tetrachloride

Methyl Ethyl Ketone

Dimethylformamide

Dimethyl Sulfoxide
Butyl Acetate (n-)
•

Trichloroethylene
Methyl Tert-Butyl
Dichloromethane
immiscible

Diisopropyl Ether

Ether (MTBE)
Ethyl Acetate
Diethyl Ether
Cyclohexane

Isopropanol
Acetonitrile

Chloroform
Acetic Acid

1-Propanol
Isooctane
miscible

Methanol
Benzene

Heptane

Pentane
Acetone

Dioxane
(DMSO)

Toluene
Butanol

Ethanol

Hexane

Xylene
(MEK)

Water
Acetic Acid • •
Acetone

Acetonitrile • • • • •
Benzene •
Butanol •
Butyl Acetate (n-) •
Carbon Tetrachloride •
Chloroform •
Cyclohexane • • • • •
Dichloroethane (1,2-) •
Dichloromethane •
Diethyl Ether • •
Diisopropyl Ether • •
Dimethylformamide • • • • • • •
Dimethyl Sulfoxide (DMSO) • • • • • • •
Dioxane

Ethanol

Ethyl Acetate •
Heptane • • • • •
Hexane • • • • • •
Isooctane • • • • •
Isopropanol

Methanol • • • • •
Methyl Ethyl Ketone (MEK) •
Methyl Tert-Butyl Ether (MTBE) •
Pentane • • • • • •
1-Propanol

Tetrahydrofuran (THF)

Toluene •
Trichloroethylene • •
Water • • • • • • • • • • • • • • • • • • • •
Xylene • • • •
The life science business of Merck
operates as MilliporeSigma in the
U.S. and Canada.