Cardiovascular Diseases and Conditions -

Hereditary Hemorrhagic Telangiectasia; Recent

Studies from University of Alberta Add New Data
to Hereditary Hemorrhagic Telangiectasia (Links
Between Strokes and Hereditary Hemorrhagic
Telangiectasia: A Population-Based Study)
Publication info: Women's Health Weekly ; Atlanta [Atlanta]20 Dec 2018: 1270.

ProQuest document link

FULL TEXT
2018 DEC 20 (NewsRx) -- By a News Reporter-Staff News Editor at Women's Health Weekly -- Research findings on
Cardiovascular Diseases and Conditions - Hereditary Hemorrhagic Telangiectasia are discussed in a new report.
According to news reporting originating in Edmonton, Canada, by NewsRx journalists, research stated, "Hereditary
hemorrhagic telangiectasia (HHT) is a disease of abnormal vasculature where patients are predisposed to strokes
of multiple etiologies. We assessed yearly stroke incidence among Albertans with HHT and compared with the
general population."
The news reporters obtained a quote from the research from the University of Alberta, "Given the tendency for
stroke in HHT patients, we expected HHT patients to have higher stroke incidence, in particular at younger ages.
Population-based administrative health data on inpatient and ambulatory admissions were extracted over a 16-
year period using International Classification of Diseases (ICD)-9 and ICD-10, Canada codes. We analyzed overall
occurrence of strokes in Alberta by age, gender, stroke subtype, and diagnosis of HHT. The age-standardized
incidence rate of stroke in HHT was 450 per 100,000 compared with 260 per 100,000 in the general population with
a rate ratio of 1.73 (95% confidence interval (CI) [1.046-2.842]). This study found a higher HHT prevalence in
Alberta (1 in 3800) compared to the world average of 1 in 5000. Women were also more likely to be diagnosed with
HHT, with a 3.25:1 female gender preponderance in the yearly incidence.InterpretationThis study not only shows
that HHT patients are at higher risk of having a stroke but also quantifies that risk using an age-adjusted metric in
Alberta. This province has a higher than expected disease burden of HHT, with the majority of cases affecting
women. Our study found that acute ischemic strokes and transient ischemic attacks are far more common than
hemorrhage in HHT."
According to the news reporters, the research concluded: "As HHT is a rare, multi-system, chronic disease, these
patients should be referred to an HHT Centre of Excellence."
For more information on this research see: Links Between Strokes and Hereditary Hemorrhagic Telangiectasia: A
Population-Based Study. The Canadian Journal of Neurological Sciences, 2018;():1-7. The Canadian Journal of
Neurological Sciences can be contacted at: Canadian J Neurol Sci Inc, PO Box 4220, Station C Editorial
&Subscription Serv, Calgary, Ab T2T 5N1, Canada.
Our news correspondents report that additional information may be obtained by contacting F.N. Chowdhury, Dept.
of Medicine, Division of Pulmonary, University of Alberta, Edmonton, Alberta, Canada. Additional authors for this
research include G.S. Chandrarathne, K.D. Masilamani, J.TN. LaBranche, S. Malo, L.W. Svenson, T. Jeerakathil and
D.P Vethanayagam.
The publisher of the The Canadian Journal of Neurological Sciences can be contacted at: Canadian J Neurol Sci

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Inc, PO Box 4220, Station C Editorial &Subscription Serv, Calgary, Ab T2T 5N1, Canada.
Keywords for this news article include: Canada, Stroke, Alberta, Edmonton, Hematology, Dermatology,
Epidemiology, Gender Health, Women's Health, Gender and Health, Health and Medicine, Risk and Prevention,
North and Central America, Hereditary Hemorrhagic Telangiectasia, Cardiovascular Diseases and Conditions,
Cerebrovascular Diseases and Conditions.
Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2018, NewsRx
LLC
The citation for this news report is: NewsRx. Recent Studies from University of Alberta Add New Data to Hereditary
Hemorrhagic Telangiectasia (Links Between Strokes and Hereditary Hemorrhagic Telangiectasia: A Population-
Based Study). Women's Health Weekly. December 20, 2018; p 1270.

DETAILS

Subject: Population; Womens health; Stroke; Disease; Gender; Health risk assessment

Location: Canada Calgary Alberta Canada Edmonton Alberta Canada Central America

Company / organization: Name: University of Alberta; NAICS: 611310

Identifier / keyword:
Edmonton Alberta Canada North and Central America Cardiovascular Diseases and C
onditions Cerebrovascular Diseases and Conditions Dermatology Epidemiology
Gender Health Gender and Health Health and Medicine Hematology Hereditary
Hemorrhagic Telangiectasia Risk and Prevention Stroke Telangiectasia Women's
Health

Publication title: Women's Health Weekly; Atlanta

First page: 1270

Publication year: 2018

Publication date: Dec 20, 2018

Publisher: NewsRx

Place of publication: Atlanta

Country of publication: United States, Atlanta

Publication subject: Medical Sciences, Women's Interests

ISSN: 10787240

Source type: Wire Feeds

Language of publication: English

Document type: News

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 ProQuest document ID: 2155344556

Document URL: https://search.proquest.com/docview/2155344556?accountid=149218

Copyright: Copyright 2018, NewsRx LLC

Last updated: 2018-12-13

Database: ProQuest Central

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