Schematic Diagram of Pathophysiology

Modifiable Factors: Non-Modifiable Factors:

-stress -decreased level of progesterone
-fatigue caused -aging pf placenta
overworking -oxytocin release
-strenuous works -prostaglandin cascade
-fetal adrenal maturation
-engagement of the presenting part

Onset of
Labor

Uterine contractions that result

to cervical dilatation
interleukin-8
decidua produces prostaglandin E2 and

decrease synthesis of collagen

increase in uterine increase in
activity production of MMP

PRETERM PREMATURE
RUPTURE OF MEMBRANES
wound
healing
mediate Second Stage of Labor
d by the
(cardinal movements of the fetus)
clotting Mother
uterusback
en- to
gback level of hormones separation and
factors ThirdpreStage- ant active systems back
episiotomy ptostrof r Po atum
peLabor expulsion of placenta
p ar e to normal
nt

babckleetodin
nogrmal