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Unp-Cn Do Not Reproduce: Course Learning Outcomes
Unp-Cn Do Not Reproduce: Course Learning Outcomes
This module will introduce to the art and science of Oncology Nursing. Oncology patients receive
care from all health care settings-including acute care teaching hospitals, tertiary care centers,
general hospitals and community care. Given the increasing complexity of the growing population,
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caring for people with cancer and their families involves a particular set of advanced skills and
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knowledge. Furthermore, this module provides essential discussion on the concepts of the Female
Reproductive Disorders such as Cervical cancer, ovarian cancer and uterine cancer including its
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management.
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Course Learning Outcomes:
At the end of the module, the learners will be able to:
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1. Identify risk factors and clinical manifestations of the disease.
2. Summarizes the disease process for some female reproductive disorders such as cervical,
ovarian and uterine cancer.
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3. Explain collaborative management including the nursing responsibilities.
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Read and analyze each question and encircle the best answer.
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e.
Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
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c. In egg-forming germ cells with in the ovary
d. Any of these
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5. Who is the most at risk for developing ovarian cancer?
a. A woman who has had multiple children
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b. A woman who is underweight
c. A woman over the age of 60
d. Any of the above
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6. Which of the following is usually one of the earliest symptoms of uterine cancer?
a. Abnormal or excessive bleeding without pain
b. Excessive bleeding and pelvic pain
c. Abdominal pressure and watery discharge
d. Enlarged lymph nodes
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7. Which treatment option/s are best while the cancer is still localized to the uterus?
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a. Surgery
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b. Hormone therapy
c. Surgery and chemotherapy
d. Surgery and hormone therapy
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8. Which of the following is considered a main risk factor and a necessary cause of cervical
cancer?
a. Human torovirus
b. Human papillomavirus
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c. Rotavirus
d. Coronavirus
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9. Which of the following tests can be used to detect precancerous stages of cervical
cancer?
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a. Mammography
b. Pap test
c. Blood test
d. Cone Biopsy
10. High fat diet may be factor in the development of certain cancer of the:
a. Breast and colon
b. Prostate
c. Uterine
d. All of the above
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Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
CERVICAL CANCER
It is the 3rd most common cancer worldwide.
Occurs most commonly in women ages 30-40 years old, but can occur as early as age 18.
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A type of cancer that occurs in the cells of the cervix.
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It is the only gynecological Ca that can be prevented through routine screening.
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Risk Factors:
1. Human Papilloma Virus (HPV) infection
-Vaccination against HPV is effective to avoid HPV infection.
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2. Cigarette smoking, both active and passive.
3. Reproductive behavior including early 1st intercourse and early childbearing
-Screening via gynecological exams and Pap Smear, with treatment of precancerous abnormalities,
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decreases the incidence and mortality of cervical cancer.
4. Low socioeconomic status (maybe related to early marriage and early childbearing)
5. Nutritional deficiencies (folate, beta-carotene and vitamin C levels are lower in women with
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cervical cancer than in women without it.)
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7. Hematuria
8. Weight loss, anemia and fever- signal advanced disease
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Most cancers originate in squamous cells, while remainder are adenocarcinomas or mixed
adenosquamous carcinomas.
Adenocarcinomas begin in mucus- producing glands and are and often due to HPV
infection.
Most cervical cancers, if not detected and treated, spread to regional pelvic lymph nodes.
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Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
Diagnostic Evaluation:
1. Annual Pap test-
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o should begin 3 years after 1st sexual intercourse, but no later than age 21.
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o at 30 y/o, women who have had 3 normal pap test result in a row may get screened
every 2-3 years.
o At 70 or older, may decide with their health care provider after having no abnormal
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Pap test in the 10 years to stop having Pap tests.
o Women who have had a total hysterectomy, do not need to screened for cervical Ca,
unless the surgery was done for cervical precancer or cancer.
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o The finding of an abnormal Pap test indicates the need for follow up:
o Women with minor changes may be followed with a repeated pap test in 4-6 months
for 2 years.
2. Colposcopy RE
o involves examination of the cervix with a binocular microscope w/ low levels of
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magnifications.
o Helps in the identification of possible epithelial abnormalities and suggests areas for
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biopsy.
3. Metastatic work ups (CXR, CBC, Dilation and Curettage (D&C), CT Scan, MRI and IV
urography)
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MEDICAL TREATMENT:
o Precursor or Pre-invasive lesion:
Loop Electrocautery Excision Procedure (LEEP)
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- It is used to remove abnormal cells where a thin wire with laser is used to cut away a thin
layer of cervical tissue.
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Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
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normal tissue remains in the cervix.
- Conization may be performed in conjunction with LEEP.
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- Conization removes the cone-shape tissue for biopsy and LEEP is used to remove abnormal
tissue.
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o Invasive Cancer:
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Total hysterectomy- removal of the uterus, cervix and ovaries
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Radical hysterectomy – removal of uterus, ovaries, fallopian tubes, proximal vagina
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pelvic lymph nodes and construction of diversional conduit, colostomy and vagina
Radical trachelectomy – removal of the cervix and selected nodes to preserve
childbearing capacity in a woman of reproductive age with cervical cancer.
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Cryosurgery - Involves freezing of the tissues using a probe, with subsequent necrosis
and sloughing.
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NURSING RESPONSIBILITIES:
1. Encourage client to use relaxation technique to promote comfort during diagnostic
procedures.
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3. Watch for complications related to therapy to ensure that measures can be instituted to
prevent complications.
4. Assess pain level and administer pain medications, as needed and note its effectiveness to
promote comfort.
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5. Maintain diet to promote recovery.
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NO
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2. Cite three goals of collaboration care for the client with preinvasive cancer of the
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cervix.
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3. What can the nurse do to help the client with invasive cervical cancer cope with the
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situation while she is being prepared for a treatment such as hysterectomy.
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OVARIAN CANCER
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sex-cord stromal cell – cancer of the cells that release female hormones. This uncommon form
of ovarian cancer can affect women of any age
borderline tumors – types of epithelial tumors that are not as aggressive as other forms.
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CONTRIBUTING FACTORS:
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Age at menopause
- Most ovarian cancers occur in women over 50 years, with the highest risk for those over
60
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Exposure to asbestos, talc and industrial pollutants
- Asbestos-contaminated talcum powder products have caused cancer in people who
inhaled the powder on a regular basis. Some researchers suggest when women applied
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contaminated talcum powder to their genitals after showering or bathing, asbestos fibers
may have also traveled up the reproductive tract to their ovaries.
Familial tendency and history of breast or uterine cancer
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- Genetic predisposition is the strongest risk factor for ovarian cancer. Women who have
relatives with ovarian cancer have an approximately 3-fold increased risk, with multiple
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affected relatives further raising the risk.
Fertility drugs
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- Use of fertility drugs is highly correlated with many other factors that affect ovarian cancer
risk, which complicates teasing out the contribution of fertility drug treatments.
- Fertility drugs promote maturation of multiple follicles and, consequently, multiple
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increases risk of ovarian cancer. The association of total fat intake with ovarian cancer may
be modified by hormone and reproductive factors such as parity and oral contraceptive use.
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III – Growth involves 1 or both ovaries with metastases outside the pelvis or
positive retroperitoneal or inguinal nodes
ASSESSMENT FINDINGS:
Symptoms are often vague, and many women ignore the symptoms. Ovarian cancer is often
silent, but enlargement of the abdomen from accumulation of fluid is the most common sign.
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Pelvic or abdominal pain
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Bloating
Urinary urgency or frequency
Difficulty in eating or feeling full quickly
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Ovarian cancer metastasizes by shedding malignant cells, which frequently
implant on the uterus, bladder, bowel, and omentum. Ovarian cancer can also
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metastasize by lymphatic spread.
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DIAGNOSTIC TEST:
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Abdominal ultrasonography, CT scan or X-ray may delineate tumor size.
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TREATMENT:
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Conservative treatment:
The following conservative approach may be appropriate:
1. Resection of the involved ovary
2. Biopsies of the omentum (a large flat adipose tissue layer nestling on the surface of the
intra-peritoneal organs) and the involved ovary
3. Peritoneal washing for cytologic examination of pelvic fluid
4. Periodic chest x-ray to rule out lung metastasis.
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Aggressive treatment:
Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
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In total abdominal hysterectomy and bilateral salphingo-oophorectomy (TAHBSO), a surgery
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will be done through an incision in the abdomen. A bilateral salpingo-oophorectomy is
surgery to remove both of the ovaries and fallopian tubes. The hysterectomy and bilateral
salpingo-oophorectomy will both be done during one procedure. This surgery will remove the
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uterus, cervix, ovaries, and fallopian tubes. After a hysterectomy, the patient will no longer
have periods or be able to become pregnant
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For ovarian cancer in younger women wishing to preserve their
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fertility, it may be possible to leave the healthy ovary and uterus.
This is possible if the tumor is localized to one ovary and the patient is
at low risk for recurrence.
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Pharmacologic Therapy:
Chemotherapy
Paclitaxel, Cisplatin, Carboplatin are most often used because of their excellent clinical
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Altretamine (Hexalen) -are used for palliative treatment of persistent, recurrent ovarian
cancer
Paclitaxel (Taxel) and Topotecan (Hycamtin) -are used to treat metastatic ovarian
cancer.
Gemcitabine (Gemzar) and Carboplan (Platinol) are used to treat recurrent ovarian
cancer.
Liposomal therapy – delivery of chemotherapy in a liposome.
- Allows the highest possible dose of chemotherapy to the tumor target with a reduction in
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adverse effects.
Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
- Liposomes are used as drug carriers because they are nontoxic, biodegradable, easily
available, and relatively inexpensive.
- This is given by oncology nurse as slow IV infusion for 60-90 minutes.
- Watch out for: bone marrow suppression, GI and cardiac effects.
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SITUATION: A 62-year old female client is being evaluated for possible ovarian cancer. She has been
experiencing vague GI symptoms and urinary urgency for several months. The primary care provider has
discovered a small pelvic mass and has ordered a group of diagnostic studies.
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2. What is the purpose of exploratory surgery?
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3. What are the stages of Ovarian Cancer?
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4. What is the treatment of choice for clients with ovarian cancer?
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UTERINE CANCER
It is a slow-growing tumor arising from endometrial mucosa of the uterus, associated with the
menopausal years.
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Metastasis occurs through the lymphatic system to the ovaries and pelvis, via the blood to the
lungs, liver, and bone, or intra-abdominally to the peritoneal cavity.
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The most common gynecological cancer, and the third leading cancer in women.
Etiology: Unknown
Risk Factors:
1. Use of estrogen replacement therapy (ERT)
- Treating the symptoms of menopause with hormones is known as menopausal
hormone therapy (or sometimes hormone replacement therapy). Estrogen is the major
part of this treatment.
2
Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
- Estrogen treatment can help reduce hot flashes, improve vaginal dryness, and help
prevent the weakening of the bones (osteoporosis) that can occur with menopause.
- But using estrogen alone (without progesterone) can lead to endometrial cancer in
women who still have a uterus.
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2. Nulliparity-
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- Nulliparous women had a 24% risk of ovarian/uterine cancer compared with women
with one child, with 50% higher risk of endometroid and a 70% higher risk of clear cell
ovarian/ uterine cancer
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3. Polycystic ovary disease
- The major reason PCOS increases the risk of endometrial cancer is the prolonged exposure of
the endometrium to unopposed estrogen caused by anovulation. This prolonged exposure can
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cause endometrial hyperplasia and may lead to endometrial cancer.
4. Increased age- Most cases occur in women older than age 55.
5. Late menopause
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- If menopause occurs after age 50, the risk for this cancer might increase as the uterus
might be exposed to estrogen for more years.
6. Family Hx of uterine cancer
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Like many cancers, there is also a genetic link associated with uterine cancer. A family
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history that includes a mother, sister or daughter diagnosed with the disease puts women
at greater risk. In addition, women who have an inherited form of colorectal cancer
(known as Lynch syndrome) have a 60 percent higher risk of developing uterine cancer.
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7. Obesity
- Obesity is a strong risk factor for endometrial/uterine cancer and linked to hormone
changes. A woman's ovaries produce most of her estrogen before menopause. But fat
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tissue can change some other hormones (called androgens) into estrogens. This can
impact estrogen levels, especially after menopause. Having more fat tissue can increase a
woman's estrogen levels, which increases her endometrial cancer risk.
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- Gaining weight as you get older age and weight cycling (gaining and losing a lot of weight
many times in your life) have also been linked to a higher risk of endometrial cancer after
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menopause
8. Hypertension
- Published observational studies of hypertension and the risk of endometrial cancer and
our results confirm that hypertension is a strong risk factor for endometrial cancer with a
61% increase in the relative risk
9. Diabetes mellitus
- Disorders associated with hyperglycemia (Type I and II diabetes mellitus) have an increased risk
of Endometrial/ uterine Cancer, indicating that poor control of blood glucose may be an
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Diagnostic Evaluation:
1. Pelvic examination -may reveal an enlarged uterus, and endocervical aspirate may show
abnormal cells.
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2. Endometrial biopsy- may be helpful, but is not sensitive
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3. Dilation and curettage -most accurate diagnostic tool
4. Additional testing includes metastatic workup (X-ray studies and cystoscopy)
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Management:
1. Radiation Therapy – is the usual treatment, either after surgery, or instead of surgery in
advanced cases. Therapy may be intracavitary or external; it is individualized according to the
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stage of disease and the patient’s response to and tolerance of radiation.
a. Intracavitary radiation – radium by way of applicator in endocervical canal.
Applicator remains in place 24 to 72 hours.
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Complications include hemorrhagic cystitis, proctitis, vaginal stenosis, uterine
perforation.
b. External radiation – by way of linear accelerator or cobalt.
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External radiation over pelvis may supplement intracavitary radiation to eliminate
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metastatic disease.
- Tamoxifen (Nolvadex), an antiestrogen, also may be described.
4. Surgery
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NURSING RESPONSIBILITIES:
A. Monitoring
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1. Monitor patient’s response to pain control medication.
2. Observe for s/s of radiation sickness: N/v, fever, diarrhea, abdominal cramping.
3. Monitor for complications of surgery – bleeding, infection.
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B. Administer pain medications and encourage use of relaxation techniques such as DBE,
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Inspect IFC frequently to ensure proper drainage. A distended bladder may cause severe
radiation burns.
Encourage oral fluids to prevent bladder infection.
Check patient frequently to minimize anxiety, but minimize time spent at bedside to
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reduce radiation exposure.
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During radiation removal:
Make sure that sterile gloves, long forceps, and lead container are available.
Check number of tube removed against number applied; should be noted in chart.
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Practice radiation precaution in handling and returning source to radiation dept.
Administer cleansing enema and douche before the patients gets out of bed.
Provide assistance during ambulation because of postural hypotension from prolonged
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bedrest.
C. Education and Health Maintenance:
Explain that surgery or radiation therapy does not prevent satisfying sexual activity.
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NO
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SITUATION: A 53-year old woman with dysfunctional uterine bleeding underwent an abdominal
hysterectomy and oophorectomy this morning. Her VS are stable and her dressing is dry and intact. She is
able to administer her own pain medication by means of PCA (Patient-controlled analgesia).
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2. How can a hysterectomy have both a negative and positive effect on a woman’s image?
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Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
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3. Agree with or refute the idea that women undergoing a vaginal hysterectomy have fewer problems than
women undergoing an abdominal hysterectomy?
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NO
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REFERENCES:
Black, J.M & Hawks, J.H. 2009. Medical-Surgical Nursing “Clinical management for positive
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outcomes.
REFLECTION:
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Write a reflection about your personal experience caring for a patient with cancer.
Republic of the Philippines
UNIVERSITY OF NORTHERN PHILIPPINES
Tamag, Vigan City
2700 Ilocos Sur
College of Nursing
Website: www.unp.edu.ph
Mail: unp_nursingvc@yahoo.com
CP# 09177148749, 09175785986
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