MATERIAL SAFETY DATA SHEET

ON
ACETONE

Submitted by: Nacario, Stephanie I.

B. MSDS image
Classification of the substance or mixture
According to Regulation EC 1272/2008 classified as Flammable Liquid Category 2, Eye Irritant
Category 2, Specific Target Organ Toxicity Single Exposure Category 3.

Label element
GHS Pictogram Signal Word Hazard Class
Danger Flammable Liquids, Category
2
Eye Irritation, Category 2
Specific Target Organ
Toxicity-
Single Exposure, Category 3

Hazard Statements Precautionary statements

H225: Highly flammable liquid and vapor. P210: Keep away from heat/sparks/
open flames/hot surfaces – No smoking.
H319: Causes serious eye irritation P305+351+338: IF IN EYES: Rinse cautiously with
water for several minutes. Remove contact lenses if
present and easy to do – continue rinsing.
H336: May cause drowsiness or dizziness
P337+313: Get medical advice/attention.
P403: Store in a well-ventilated place.
Classification System
Acetone, or propanone, is an organic compound with the formula (CH3)2CO. [15] It is the simplest and
smallest ketone. It is a colorless, highly volatile, and flammable liquid with a characteristic pungent odor.

Substances Substance CAS- No Percentage % Acetone 67-64-1 >99

Chemical Formula % by
Components CAS# Formula Weight Hazardous Weight
Acetone 67-64-1 C3H6O 58.08 Yes >99.5

FIRE FIGHTING MEASURES

NFPA Ratings: Health: 2 Flammability: 3 Reactivity: 0
Flammable Properties: HIGHLY FLAMMABLE! Vapors may cause a flash fire or ignite explosively. Vapors
may
travel considerable distance to a source of ignition and flash back. Heat may cause sealed
containers to explode.
Flash Point: -20° C (-4° F) Closed Cup
Auto-ignition Temp: 465° C (869° F)
C. Analysis

Composition/Information on ingredients
3.1. Substances
Substance type: Mono-constituent
Name Product identifier % GHS-US classification
Acetone
(Main constituent)
(CAS-No.) 67-64-1 100 Flam. Liq. 2, H225
Eye Ifrit. 2A, H319
STOT SE 3, H336
Full text of hazard classes and H-statements: see section 16

HANDLING AND STORAGE

Handling: Do not handle or open near flame, sources of heat, or sources of ignition. Protect material
from direct sunlight. Wear personal protective equipment (see section 8). Use only in well ventilated areas.
Provide sufficient air exchange and/or exhaust in work rooms. Avoid
contact with skin, eyes, and clothing. Do not breathe vapors or spray mist. Do not ingest.
When using, do not eat, smoke, or drink. Take precautionary measures against static
discharge. Keep away from incompatible materials. Handle in accordance with good
Product: Acetone
Revision Date: 12/03/2012 4/8
industrial hygiene and safety practice. Wash thoroughly after handling. Containers of this
material may be hazardous when empty since they retain product residues (vapors, liquids).
Observe all warnings and precautions listed for the product
Storage: Store in a cool, dry, ventilated area. Store away from flame, sources of ignition, heat, and
incompatible materials. Store in original container. Keep containers tightly closed and
upright. Keep away from food, drink, and animal feeding stuffs. Keep out of the reach of
children. Ground container and transfer equipment to eliminate static electric sparks.
Comply with all national, state, and local codes pertaining to the storage, handling,
dispensing, and disposal of flammable liquids.

EFFECTS
Main Routes of Exposure: Inhalation. Skin contact. Eye contact.
 Inhalation: Can irritate the nose and throat. At high concentrations: can harm the nervous system.
Symptoms may include headache, nausea, dizziness, drowsiness, and confusion. A severe exposure
can cause unconsciousness.
 Skin Contact: May cause mild irritation. Can be absorbed through the skin, but harmful effects are
not expected.
 Eye Contact: EYE IRRITANT. Causes moderate to severe irritation. Symptoms include sore, red eyes,
and tearing. The vapor also irritates the eyes.
 Ingestion: Not harmful. If large amounts are ingested: Can cause effects as described for inhalation.
 Effects of Long-Term (Chronic) Exposure: Can cause dry, red, cracked skin (dermatitis) following
skin contact. May harm the nervous system. Conclusions cannot be drawn from the limited studies
available.
 Carcinogenicity: Not known to cause cancer.
International Agency for Research on Cancer (IARC): Not specifically evaluated.
American Conference for Governmental Industrial Hygienists (ACGIH): A4 - Not classifiable as a human
carcinogen.
 Teratogenicity / Embryotoxicity: Not known to harm the unborn child.
 Reproductive Toxicity: Not known to be a reproductive hazard.
 Mutagenicity: Not known to be a mutagen.

TREATMENT PROCEDURE
Inhalation: Take precautions to prevent a fire (e.g. remove sources of ignition). Move victim to fresh air.
Call a Poison Centre or doctor if the victim feels unwell.
Skin Contact: Take off contaminated clothing, shoes, and leather goods (e.g. watchbands, belts). Flush with
lukewarm, gently flowing water for 5 minutes. If irritation or pain persists, see a doctor. Thoroughly clean
clothing, shoes and leather goods before reuse or dispose of safely.
Eye Contact: Immediately flush the contaminated eye(s) with lukewarm, gently flowing water for 15-20
minutes, while holding the eyelid(s) open. If a contact lens is present, DO NOT delay flushing or attempt to
remove the lens. Take care not to rinse contaminated water into the unaffected eye or onto the face. If
irritation or pain persists, see a doctor.
Ingestion: Have victim rinse mouth with water. Call a Poison Centre or doctor if the victim feels unwell.
First Aid Comments: All first aid procedures should be periodically reviewed by a doctor familiar with the
chemical and its conditions of use in the workplace.
CONTRAINDICATION/OTHER REMEDIES

Contraindication can be described as a special circumstance or a disease or a condition wherein you are
not supposed to use the drug or undergo particular treatment as it can harm the patient; at times, it can
be dangerous and life threatening as well. When a procedure should not be combined with other
procedure or when a medicine cannot be taken with another medicine, it is called Relative
contraindication. Contraindications should be taken seriously as they are based on the relative clinical
experience of health care providers or from proven research findings.

Isopropyl Alcohol (Acetone Alcohol Pad) should not be used in patients with epilepsy or urinary tract
infection. 5% Isopropyl Alcohol (Acetone Alcohol Pad) in 5% Dextrose Injection, USP is contraindicated in
diabetic coma.

 Isopropyl Alcohol (Acetone Alcohol Pad) is contraindicated in patients who have been addicted to
it.

 Do not give subcutaneously and avoid extravasation during intravenous administration.

 STABILITY AND REACTIVITY

Stability: Stable under normal conditions.
Conditions to Avoid: Heat, flames, sparks, ignition sources, incompatibles
Incompatible Materials: Oxidizing agents, acids, alkalis, peroxides
Hazardous Decomposition Carbon dioxide and carbon monoxide may form when heated to
decomposition.
Products:
Possibility of Hazardous Can react vigorously, violently or explosively with incompatible materials listed
above.
Reactions:
Hazardous Polymerization: Will not occur

Conclusion

The goal of this lab was to experimentally determine how the concentrations of Acetone and H+
affect the rate at which I2 disappears in a reaction by calculating the values of k, the exponents x and y,
and putting those values into the rate law equation. Those numbers were found by altering the amounts of
either acetone or H+ used in each trial, which made it possible to use an equation provided above to solve
for the value of k, and the exponents, x and y, in the rate law equation. It was found that both Acetone and
H+ have a direct effect on the reaction rate of I2. The rate law for acetone iodination is rate= k[Acetone]
[H+]. The average value of k calculated from the three trials was found to be about 2.32e-5 M-1s-1.