Professional Documents
Culture Documents
BSN II-C
Name and classification Onset, Peak, Duration, Mechanism of action Indication Contraindication Adverse effect Nursing responsibilities
of the drug Route
Generic Name: Routes of Metoclopramide causes General indications: Contraindications: Extrapyramidal Assess pt for
Metoclopramide administration: PO, IV, antiemetic effects by amebic hepatic hypersensitivity movement disorders are extrapyramidal
Topical inhibiting dopamine D2 abscess hypersensitivity to no frequent with small symptoms and tardive
Trade name: Flagyl, and serotonin 5-HT3 intestinal parabens doses, but relatively dyskinesia (more likely
Metric 21, noritade Pharmacokinetics: receptors in the amebiasis first trimester of common with high doses in older pts)
chemoreceptor trigger trichomoniasis pregnancy (up to 30%). Acute Assess for
Classification: Onset: zone (CTZ) located in retractory dystonia/dyskinesia gastrointestinal
Nitroimidazole PO: unknown the area postrema of the trichomoniasis Precautions: (akathisia, trismus, complaints, such as
IV: immediate brain. Administration of bacterial history of blood oculogyric crises) occur nausea, vomiting and
Therapeutic class: Topical: unknown this drug leads to infections caused dyscrasias: mainly in children and constipation
antibacterial, prokinetic effects via by anaerobic seizures or young women and can In oral administration,
antiprotozoal Peak: inhibitory actions on microorganisms neurologic be life threatening in for better absorption
PO: 1-2 hrs presynaptic and to prevent problems certain circumstances. In allow 30 minutes to one
Patient’s Dose: 1.5 mg IV: immediate postsynaptic D2 postoperative severe hepatic longer-lasting hour before eating
slow IV stat Topical: 6-10 hrs receptors, agonism of infection in impairment treatments, parkinsonism Advise pt to Rinse
serotonin 5-HT4 contaminated pregnancy, or tardive dyskinesia mouth frequently to
Minimum Dose: PO: 250 Duration: receptors, and colorectal lactation and may occur; these mostly combat dryness.
mg TID PO, IV, Topical: antagonism of surgery children affect elderly people and Patient Teaching
IV: 100mg/ml unknown muscarinic reptor pelvic inflammatory Drug interactions: they are only slowly Metoclopramide can
inhibition. This action disease cimetidine reversible or even cause drowsiness.
Maximum dose: PO: 750 enhances the release of phenobarbital irreversible. Patient should avoid
mg TID 6-10 days acetycholine, causing warfarin hazardous activities
increased lower disulfiram until stabilized
esophageal sphincter flourouracil Fatigue and apathy, Store in a closed
(LES) and gastric tone, sometimes even container in a cool place
accelerating gastric depressions, have out of the reach of
emptying and transit frequently been observed children
through the gut. with metoclopramide. If there is nausea, fatty
Metoclopramide Galactorrhea and and spicy foods should
antagonizes the impotence develop due be avoided
dopamine D2 receptors. to hyperprolactinemia. Avoid alcohol or other
Dopamine exerts Arrhythmias, central nervous system
relaxant effect on the hypertension, depressants
gastrointestinal tract constipation or If a dose is missed, the
through binding to diarrhea, urticarial are patient should take it as
muscular D2 receptors. uncommon aide-effets. soon as possible. If the
next dose is due within
the next three hours, she
or he should take a
single dose immediately
and skip the next one
The drug can be safely
stopped as soon as a
patient no longer needs
it
An occasional
unintentional extra dose
is unlikely to cause
harm
A large overdose could
cause drowsiness and
muscle spasms. A
doctor should be
notified
Name and classification Onset, Peak, Duration, Mechanism of action Indication Contraindication Adverse effect Nursing responsibilities
of the drug Route
Observe 10 rights in
Trade name: Salbutamol Solution for inhalation: In low doses, acts Relief and Contraindicated with CNS: tremor, giving medications
Neb Adults: 2.5 mg TID/QID relatively selectively at prevention of hypersensitivity to nervousness, dizziness, Use minimal doses
by nebulizer. beta 2-adrenergic bronchospasm in albuterol; insomnia, headache, for minimal periods;
Generic Name: Albuterol Children ages 2 to 12: receptors to cause patients with tachyarrhythmias, hyperactivity, weakness, drug tolerance can
sulfate 0.1 mg/kg to 0.15 mg/kg bronchodilation and reversible tachycardia cause by headache, migraine. occur with prolonged
to maximum of 2.5 mg vasodilation; at higher obstructive airway digitalis intoxication used
Drug class: Antasthmatic TID/QID doses, beta 2 selectively disease. Use cautiously with CV: tachycardia, Maintain a –
is lost, and the drug acts Inhalation: treatment diabetes mellitus; palpitations, adrenergic blocker
Patient Dose: ½ ml + 1ml at beta 2 receptors to of acute attacks of hyperthyroidism, hypertension (cardio selective beta-
NSS q6 cause typical bronchospasm history of seizure blocker, such as
sympathomimetic Prevention of disorders EENT: dry and irritated atenolol, should be
Dosage: 4mg (immediate cardiac effect. exercise-induced nose and throat (with use with respiratory
release tablets) PO bronchospasm inhaled form) distress) on standby in
TID/QID; maximum Unlabeled use: case cardia
dose, 8 mg QID adjunct in treating GI: increased appetite, arrhythmias occur
serious hyperkalemia heartburn, nausea,
Frequency: q4 hours in dialysis patients; vomiting, anorexia, taste
seems to lower perversion.
potassium
concentration when Respi: bronchospasm,
inhaled by patients coughs, dyspnea,
on hemodialysis wheezing, increased
sputum
Other: hypersensitivity
reactions
Name and classification Onset, Peak, Duration, Mechanism of action Indication Contraindication Adverse effect Nursing responsibilities
of the drug Route
Generic Name: Metabolic Action: Zinc Replacement and Hypersensitivity or Gastric irritation Monitor progression
Zinc Sulfate serves as a cofactor for supplementation therapy allergy to any Nausea of zinc deficiency
more than 70 different in patients who are at components in the Vomiting symptoms during
Trade Name: enzymes. It facilitates risk for zinc deficiency formulation. Rash therapy
Zincate wound healing, normal Encourage patient to
growth and tissue repair. Use cautiously in renal comply with the diet
Classification: Mineral In patients receiving failure. recommendation
and electrolyte total parental nutrition Ask the patient to
replacements/supplement with low plasma levels notify any of the
s of zinc, dermatitis has healthcare team if he
been followed by feels nausea,
Patient Dose: 3ml OD alopecia. Zinc is an vomiting, abdominal
integral part of many pain or tarry stools
Dose: enzymes important to occur
Infants up to age 1: 5mg carbohydrate and protein Emphasize the
PO mobilization of retinal- importance of follow
Children up to 1-10: binding protein. up exams
10mg PO
Name and classification Onset, Peak, Duration, Mechanism of action Indication Contraindication Adverse effect Nursing responsibilities
of the drug Route
Generic Name: Onset: It inhibits nucleic acid General indications: Contraindications: CNS: seizures, dizziness, Before
Metronidazole PO: unknown synthesis by disrupting Amebic hepatic Hypersensitivity headache Assess pts. Infection
IV: immediate the DNA of microbial abscess Hypersensitivity to Watch carefully for
Trade name: Topical: Unknown cells. This function only Intestinal parabens EENT: tearing (topical edema because it may
Flagyl, Metric 21, occurs when amebiasis First trimester of only) cause sodium
Noritade Peak: metronidazole is Trichomoniasis pregnancy retention
PO: 1-2 hrs partially reduced, and Retractory GI: abdominal pain, Assess skin for
Therapeutic class: IV: immediate because this reduction trichomoniasis Precautions: anorexia, nausea and severity areas of local
Antibacterial, Topical: 6-10 hrs usually happens only in Bacterial History of blood vomiting, diarrhea, dry adverse reactions
Antriprotozoal anaerobic bacteria and infection caused dyscrasias; seizure mouth, glossitis Record number and
protozoans, it has by anaerobic or neurologic character of stools
Patient Dose: Duration: relatively little effect microorganisms problems Derm: rashes, urticarial, Assess pt’s and
90 mg IV q8 PO, IV, Topical: upon human cells or To prevent Severe hepatic mild dryness, skin family’s knowledge
unknown aerobic bacteria. postoperative impairment irritation of drug therapy
Minimum dose: infection in Pregnancy, During
PO: 250mg TID 6-10days contaminated lactation and Give drug with meals
IV: 100mg/mL colorectal children to minimize GI
surgery distress
Pelvic Drug interactions: To treat
inflammatory Cimetidine trichomoniasis, give
disease Phenobarbital drug for 7 days
Warfarin instead of 2-g single
Disulfiram dose
Fluorouracil Use only after T.
vaginalis has been
confirmed by wet
smear
Tablets may be
crushed for pt’s. with
difficult swallowing
Do not use aluminum
needles or hubs, color
will turn orange/rust
After
Tell pt. that metallic
taste and dark or red
brown urine may
occur
Instruct pt to take
oral form with meals
to minimize
reactions
Instruct t complete
full course of therapy
Tell pt. not to use
alcohol or drugs that
contain alcohol
May cause dizziness/
light headedness
Name and classification Onset, Peak, Duration, Mechanism of action Indication Contraindication Adverse effect Nursing responsibilities
of the drug Route
Generic Name: Gastric acid-pump Short-term treatment of Contraindicated with Diarrhea, Caution patient to
Omeprazole inhibitors: suppress activedoudenal ulcer; hypersensitivity to Nausea swallow capsules
gastric acid secretion by first-linetherapy in omeprazole or its Fatigue whole- not to open,
Brand Name: specific inhibition of the treatment of heartburn or components; Use Constipation chew or crush them.
Prilosec hydrogen-potassium symptoms of cautiously with Vomiting Arrange for further
ATP as enzyme system gastroesophageal reflux pregnancy, lactation. Dry mouth evaluation oft after
Drug classification: at the secretory surface disease (GERD): short- Dizziness 8 weeks of therapy
Proton Pump Inhibitors of the gastric parietal term treatment of active Headache for gastro reflux
(PPI) cells; blocks the final benign gastric ulcer; Skin rashes disorders; not
step of acid production. GERD, severe erosive Weakness intended for
esophagitis, poorly maintenance
responsive symptomatic Back pain therapy
GERD; Long-term Upper Administer antacids
therapy: treatment of respiratory with omeprazole, if
pathologic infection need
hypersecretory Coughing
conditions (Zollinger- Teaching Points:
elliso Syndrome,
multiple adenomas, Take the drug before
systemic mastocytosis) ; meals. Swallow the
Eradication of H. pylori capsules whole; do
with amoxicillin or not chew, open or
metronidazole. crush them. This drug
will need to be taken
for up to 8 wk (short-
term therapy) or for a
prolonged period (> 5
yr in some cases0.
Have regular medical
follow-up visits.