Engineering cence and Tech Contents lists availabe at S Engineering Science and Technology, an International Journal ELSEVIER journal homepage: www.elsev' Full Length Article Characterization and antibacterial activity of nickel ferrite doped «- alumina nanoparticle comilocate/jestch Qe Karim Ishaq’, Abdulkareem Ambali Saka *°, Abubakre Oladiran Kamardeen*“, Aliyu Ahmed“, Mohammed Is‘haq Alhassan”, Hamidu Abdullahi ‘nsecnolgy strc Group Cente for Genetic gnerng and itcbnoloy (CGE) Federal Univers 6f Teenabg. PMS, Bos. toa, ier tte. geo "Deparment of Cher ninecring Schon o nginerng an Engineering Tenby, Feel Univers rgieringSchol fEgincting and Einering Teche Feder Univers of Technolgy, PLB 6, ada Kvae, Mina Mige tae Mea "Deparment of Chem Scenes Federal Univers, PMB 020, Wan Tarba Sate, Maen ARTICLE INFO ABSTRACT sr Sha ofife Sete Federal Unverity ofTechology, PMH asa Miona,Mger State Nigeria Received 25 Septenbes 2016 Reset 12 December 2018 ‘The magnetic behaviour towards Bi ferrite based nanoparticles is dependent upon the nanoparticles preparation parameters. sedicl applications of ansition metab ferrite and ansition metal his study, an txperimeal design using cental omposite design (CcD} has been explored inthe production of ai tina based nikel- ferrite nanoparticles va wet impregnation method. The effects of operating conditions $uch ap dying temperature. drying time and mass of support on the percentage yield of nicke-ferite Were studied, The optimum nickel-eriteyelé of 97452 was obtained 3175 g ef eealumina drying Sime (of 7 hand drying temperature of 116 70°C and then characterized using SEM, EDS and XRD to determine the surface morphology, elemental analysis and crystallinity respectively. the antibacterial activities of the nicke-ferites doped a-alumina were tested on Gram-negative bacterium: F ca and Peudomona cerugiosa and a Gram-positive bacterium S aureus. The asibacteval results ofthe nickel ferites doped cealumina nanoparticle on microorganisms showed thatthe nanoparticles shows no effect onthe growth ‘of. col bat depicts an inhibitory growth on Pedomonasgeruginaca and S. aureus with high antibacterial feffecton S. aureus of 170mm diameter of inhibition, Hence. the developed nickel fernites doped 9 Slumina nanoparticle shows high antibacterial effect on Pseudomonas geruginosa and S. aureus which ‘makes ia potential material for biomedical application. 1© 2016 Karabuk University. Publishing services by Elsevier BV. This isan open acces article under the CC hecepted 15 December 2016 etl compose design 1. Introduction Ternary metal oxides such as cobalt ferrite, nickel Ferrite, cupric fervite, and zinc ferite are being extensively investigated for their biomedical applications due to their favourable ferromagnetic properties Suresh etal. (8). Recently, several researches showed the antibacterial potentials of these metal-oxide systems. Numer- us areas of applications of the Nano-ferrtes have been identified in several technological fields, making it one of the major focuses of nanotechnology research in the last decade |). The various applications are as a result of the interesting and extraordinary characteristics of these fetttes which include their improved elec- Lwonic, magnetic, optical as well as catalytic properties, On the area offerstes as an excellent catalyst material, it high chemical stabil- ‘mal adres shagotuninn dg (K ag) er review inder responsi of Karak Univer ap ton ech 20161208 2215-088) 2016 Karabok Unies Publehing secs by BY-NC-ND license (ht /creativecommansorglcenss/by-ne-nd40) ity enhances this property most especialy in the area of carbon nanotubes prodiction via catalytic vapour deposition (CVD) tech- niques (4) ‘The magnetic nanofertites are generally represented a8 MFe30, ‘where M represents either of Ni Co, or Cu that are tetrahedral sites, ‘of typical bivalent cations in a cubic lattice structure (5), Uniquely, the nanoferrites of nickel are known fo possess distinctive proper- ties of high permeability when subjected to an elevated frequency and electrical resistivity. This exceptional property of nickel ferrite in the group of cubic ferromagnetic oxides is possible due to i ability fo exhibit a surface disorderliness. Considering the avail- ability, suitability and wide application of Alumina in various applications, an effectively designed hybrid system of Alumina- based Nickel ferrite would be valuable towards possible applica- tion as antimicrobial or drug delivery agents to targeted organs ‘in the human body system, Various methods have been used previously for the synthesis of ‘magnetic ferrites nanoparticles. Such methods include sol- (eativecommnsar[censsfy-n- 40).