T H E R A P E U T I C I N D E X

Rostil®
Tablet

Description
Rostil is a musculotropic antispasmodic agent available as film coated
tablet, each containing 135 mg of Mebeverine Hydrochloride BP. It acts
directly on smooth muscle of gastrointestinal tract and is used to treat
bowel spasm.

Indications
Rostil is indicated :

♦ for the symptomatic relief of irritable bowel syndrome

♦ other conditions include;
- Chronic irritable colon
- Spastic constipation
- Mucous colitis
- Colicky abdominal pain and cramps
- Persistent non-specific diarrhoea

Dosage and Administration

Adults (including elderly) : One tablet three times a day, preferably 20
minutes before meals. After a period of several weeks when the desired
effect has been obtained, the dosage may be gradually reduced.

Contraindication
None known.

Drug Interactions
None known.

Side Effects
There are no known life threatening toxic effects of Rostil. There are few
reported cases of overdose with Mebeverine.

Use in Special Populations

Neonates : Not recommended for neonates.

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Children : The preparation is only recommended for children over 10 years.

Pregnancy : No teratogenicity has been shown in animal experiments and

there are no known teratogenic effects in human.

Commercial Pack
Rostil® Tablet : Box containing 5 blister strips of 10 tablets, each tablet
contains Mebeverine Hydrochloride BP 135 mg.

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