Cell Analysis Global Market

–Forecast to 2027

Cell Analysis Global Market is estimated to be worth $33.5 billion by 2027

IQ4I Research & Consultancy published a new report on “Cell Analysis Global
Market – Forecast To 2027” This report analyzes and studies the overall market, major
Drivers & Opportunities, Restraints & Threats in North America, Europe, Asia-Pacific and
Rest of the World.

IQ4I’s Report Contains 136 market data tables and 102 figures spread through 653
pages and an exhaustive TOC on “Cell Analysis Global Market”, [TECHNIQUES (PCR,
Sequencing, Microfluidics & Microarrays, Microscopy, Cytometry, High Content
Screening & Spectrometry, Electrophoresis and Others)); PRODUCTS (Consumables
(Assay Kits, Reagents, Microplates, Cell Culture Consumables, Others), Instruments
(Cell Counters, Cell Microarray and Microfluidics, Liquid Handling Systems,
Cytometers, High Content Screening, Microplate Readers, PCR Instruments,
Sequencing Instruments, Spectrometers, Microscopes & Other instruments)
Softwares and Services); APPLICATIONS (By Process, By-Field & By-Therapeutic
areas), END-USERS (Hospitals & Diagnostic Labs, Academic & Research Institutes,
Diagnostic Labs CROs, Pharma & Biotech Companies, Cell Banks, & Others);
REGIONAL (North America, Europe, Asia Pacific and Rest of the World)].

Cell analysis encompasses a wide range of activities that help in understanding and
predicting the dynamics that influence cell function, proliferation, growth and death. This is
enabled through analysis of cell signaling mechanisms, elucidation of molecular function,
study of cell behavior, and correlating to multiple events with cell morphology, changes in
biochemical constituents and cell health. Cell analysis is gaining importance in various fields
of applications such as drug discovery, diagnosis of infectious disease, cancer research, and
diagnosis of genetic diseases. Live-cell imaging, single-cell analysis, and high content
screening (HCS) are some of the few technological processes gaining more focus in recent
times. Single-cell analysis is a rapidly evolving field where individual cells are analyzed for
assessment of changing cell behavior and function over time during its natural states or
when perturbed by external factors, it is gaining prominence in the cell analysis market
because of its extensive application in different research areas.

According to IQ4I analysis, the cell analysis global market is expected to grow at mid single-
digit CAGR from 2020 to 2027 to reach $33,542.0 million by 2027. The rising incidence of
infectious and non-infectious diseases and demand for early detection, diagnosis &
treatment, increasing government and private funding, increasing advancements in cell
imaging technologies to reduce the cost & time during the drug discovery process, growing
focusing on personalized medicine, the introduction of advanced technologies in single-cell
analysis and emerging Asia-Pacific market is driving the cell analysis market growth.

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However, stringent government regulations, lack of skilled personnel to use advanced cell
analysis Instruments, and the high cost of some of the instruments are expected to hamper
the market growth.

The cell analysis market is mainly segmented by techniques, products, applications, end-
users and geography. Among the techniques, PCR accounted for the largest revenue in
2020 and is expected to grow at a mid single-digit CAGR from 2020 to 2027 due to
increased demand for molecular (PCR) based tests for disease detection especially in
infectious disease, early disease screening and prenatal testing. Microfluidics and
Microarrays is the fastest-growing segment at a high single-digit CAGR from 2020 to 2027
due to the increasing application of microfluidic technologies in single-cell isolation &
analysis and development of droplet or nanowell microfluidics platforms for single-cell omics
analysis.

The cell analysis product market is segmented into consumables, instruments and software
& services. Among these products, the Consumables segment is holding the largest share in
2020 and is expected to grow at a mid single-digit CAGR from 2020 to 2027 due to
increasing utilization of reagents and assay kits in diagnosis and research, For instance,
Recent COVID -19 pandemic situation increased utilization of PCR consumables in case of
diagnosis and Flow cytometry, sequencing, ELISPOT, Mass cytometry and others
consumables in case of research.

The cell analysis global market based on application is categorized into processes, technical
field, disease, or therapeutic area. Among the process of application, cellular process
application accounted for the largest revenue in 2020 and is expected to grow at a mid
single-digit CAGR from 2020 to 2027. Single-cell analysis market is the fastest-growing
segment at a high single-digit CAGR from 2020 to 2027 due to rising application of cell
analysis in many therapeutic areas such as cancer, immunology, neurobiology and
cardiology, development of innovative technologies for single-cell omics analysis and
emerging approach of combining technologies to address the unmet need of existing
technologies. Based on the field of application, the diagnostics sub-segment held the largest
revenue in 2020 and is expected to grow at a mid single-digit CAGR from 2020 to 2027 due
to increased incidence of cancer, increased interest in early screening & prenatal screening
of genetic diseases, decreasing test cost and the outbreak of various infectious diseases in
recent years, and advancements in analytical tools. The stem cell analysis sub-segment is
the fastest-growing segment at a mid single-digit CAGR from 2020 to 2027, due to increased

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acceptance of stem cell research and an increase in organ transplantations. Among the
different applications based on the therapeutic area, Infectious diseases accounted for the
largest revenue in 2020 and is expected to grow at a low single-digit CAGR from 2020 to
2027 due to the increasing incidence of infectious diseases have boosted the application of
cell analytical tools in diagnosis as well as research. For instance, Cytometric techniques are
greatly employed immunophenotyping of T- cell to study the immune response in COVID -19
patient samples. Cancer research is the fastest-growing segment at mid single-digit CAGR
from 2020 to 2027 due to the increasing utilization of cell analytical technologies in cancer
studies mainly to study cellular heterogeneity.

The end-users of the Cell analysis market are segmented into Hospital & Diagnostic
Laboratories, Academic and research institutes, Pharma & Biotech, Contract Research
Organization (CRO's), Cell Banks and Others. Among the end-users, Hospital & Diagnostic
Laboratories segment accounted for the largest revenue in 2020 and is expected to grow at
a mid single-digit CAGR from 2020 to 2027 attributed to the increasing adoption of early
cancer screening tests, the outbreak of infectious diseases and reduced testing cost. The
Contract Research Organization (CRO's) is the fastest-growing segment at a mid single-digit
CAGR from 2020 to 2027 due to increased outsourcing of drug discovery process which
utilizes the cell analytical technologies in various stages of drug discovery & development
such as target identification, target validation, hit optimization, toxicity and efficacy testing,
etc. and the launch of new cell analysis services.

The cell analysis global market based on geography is segmented into North America,
Europe, Asia-Pacific and the Rest of the world (RoW). Among various geographies, the
North American region dominated the cell analysis global market with the largest share in
2020 and is expected to grow at a mid single-digit CAGR from 2020 to 2027. This is due to
the increasing R&D expenditure, increasing funding for cell-based research, increasing
application cell analysis in drug discovery & development, increasing demand for
personalized medicine and early disease detection, diagnosis and treatment, increasing
focus in developing single-cell analysis technologies for application in disease research,
diagnostics and therapeutics.

The Asia-Pacific region is the fastest-growing region at a mid-single-digit CAGR from 2020
to 2027 due to increasing scope for research activities in academic & research institutes,
increasing outsourcing, increased incidence of chronic diseases (cancer) and infectious
disease, increasing awareness about early screening (cancer) and prenatal test and their

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adoption in clinical care, increasing government and private investment for - cell-based
research and also for the development & expansion of single-cell analysis technologies and
increasing number start-up companies engaged in the development innovative solutions.
However, lack of technical expertise, high cost of instruments, lack of skilled labors, and
large scale clinical data challenges are some of the restraints for the cell analysis market in
the region.

Technological advancements are expanding the cell analysis market, particularly in single-
cell analysis to enhance their application. Some of the major advancements in this field
include CRISPER Live Cell Imaging, Raman Live Cell Imaging, Deep Learning and AI in
Microscopy and development of Multi-Omics technologies, Droplet-Based Microfluidics
Inductively coupled plasma mass spectrometry, Intelligent image-activated cell sorting or AI-
driven cell isolation technology, Advanced spatial technologies, Digital Microfluidic Isolation
of Single Cells for -Omics (DISCO) technologies in single-cell analysis. Recent
advancements in microfluidic technologies have opened new avenues for single-cell
genomics, transcriptomics, and proteomics, with a particular emphasis on quantification and
multiplicity that can perform measurements on many single-cells. Droplet-based and
nanowell based microfluidic technology platforms have given significant output in - single-cell
isolation and - single-cell omics analysis. For instance, 10X Genomics developed chromium
system for single-cell gene expression sequencing, single-cell CNV and single-cell ATAC
and 1CellBio developed in-Drop system has enabled high-throughput single-cell analysis
(>10,000 cells) with intensive user support. The advancements in single-cell isolation and
barcoding technologies offer unprecedented opportunities to profile DNA, mRNA, and
proteins at the same time (single-cell multi-omics). Various single-cell genomics,
transcriptomics and proteomics methods were developed separately in recent decades, now
the focus has been towards the development of multi-omics methods. For instance, in
October 2020, Mission Bio, Inc. launched the complete Tapestri Single-cell Multi-omics
Solution (instrument, single-cell multi-omics reagent kits, TotalSeq-D antibody content from
BioLegend, and visualization software); the complete package provides layered insight into
multiple analytes across all blood cancers, reducing drug development time and cost by at
least half. Mission Bio’s new solution can uniquely detect DNA and protein simultaneously
from the same cell.

Along with these advancements in cell analysis, the trend is moving towards the merging of
or combing various cell analysis technologies or integration of various technologies such as
AI, which will have greater efficiency than the original and fills the gap between the

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technologies. For instance, Raman Confocal microscopy was developed by combining

confocal microscopy with conventional Raman spectroscopy to achieve high-resolution
label-free live cell imaging using the fingerprint peaks of biomolecules of interest such as
DNA and protein. Companies are also showing interest in these perspectives and
developing novel technologies. ThinkCyte, Inc has developed "ghost cytometry" for high-
throughput and high-content single-cell sorting by combing microfluidics, imaging and
machine learning and in July 2020, the company collaborated with Hitachi, Ltd. focused on
developing artificial intelligence (AI)-driven single-cell analysis and sorting system by
combining their technology with Hitachi's large-scale instrument manufacturing capabilities,
to enable high-speed, label-free cell isolation with high accuracy, which has been difficult to
achieve with existing cell sorting techniques.

Despite rapid advancements in single-cell isolation and analysis technologies, there is a gap
between in single-cell omics analysis and in-situ analysis because current cell analysis
technologies are unable to correlate the single-cell genomes, transcriptomes, or proteomes
with the phenotypes of adherent cells in situ (e.g., size, shape, intracellular marker
expression, and distance to neighboring cells). Thus, the focus is slowly shifting towards the
single-cell spatial analysis, where each cell is analyzed with itsnatural context. Companies
have realized the demand for these types of technologies, resulting in the development of
innovative platforms to address the unmet needs, which will drive the demand for this market
in the future. For instance, in December 2020, Nanostring revealed their new approach of
development of a spatial molecular imaging platform, a next-generation solution for
multiplexed analysis of RNA and protein expression for individual cells within a tissue
sample. The spatial molecular imager combines the power of high-plex profiling with high-
resolution imaging to enable the analysis of hundreds to thousands of RNAs or proteins
directly from single cells within morphologically intact tissue samples.

Due to the extensive advantages of cell analysis technologies in therapeutic discovery and
development, Pharma & biotech companies, academic and research institutions and CRO
are collaborating to utilize these technologies. For instance, in July 2019, Celsius
Therapeutics collaborated with Janssen Biotech, Inc. to apply its proprietary single-cell
genomics and machine learning platform to identify predictive biomarkers of response from
Janssen’s VEGA study, a Phase 2a clinical trial evaluating the efficacy and safety of
combination therapy with guselkumab and golimumab in patients with ulcerative colitis.
Similarly, in September 2020, IsoPlexis entered into a partnership with Yale University to use

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IsoPlexis' single-cell functional proteomics solutions to identify various predictive markers of

the immune response to COVID-19.

The widespread application of cell analysis, attracts the government or private ventures to
invest huge sums in this area to modernize the research and development. According to
IQ4I research, during the period 2019-20, approximately $410.8 million was invested by
various venture and government agencies in cell analysis. In that, around $xx million funding
is mainly focused on single-cell analysis. The companies are received funding mainly for the
development of innovative technologies and also to advance or accelerate the development
of their platform in various applications such as disease research, diagnosis and
therapeutics in order to expand their business in these applications. Along with this, they
also received funding for geographical and commercial expansion for their innovative
product. For instance, in December 2020, Deepcell developed a platform by combing
machine learning, microfluidics, imaging, and genomics to power phenotype activated cell
analysis and sorting in single-cell analysis. The company received $20 million series A
funding to continue the development of its microfluidics-based cell sorting and analysis
technology and to build a cell morphology atlas of more than 400 million cells, which
ultimately helps in translational research as well as in diagnostics and therapeutic
development.

The Cell analysis market is consolidated with the 6 top players occupying xx% of the market
share and the remaining xx% of the market is occupied by other players. Companies are
adopting various organic and inorganic strategies for market expansion. To gain market
share, companies are constantly focusing on developing innovative technologies and
differentiated products. For instance, in December 2020, Qiagen N.V. launched
QuantiFERON SARS-CoV-2 RUO solution that can detect T-cell responses of the human
immune system to the pathogen that causes COVID-19, help researchers find out more
about immunity levels and disease progression. Similarly, in October 2019, BD launched the
Rhapsody WTA Amplification kit for single-cell analysis on the BD Rhapsody system. The
BD Rhapsody WTA Amplification kit can be used in combination with BD AbSeq reagents to
simultaneously study the entire transcriptome and protein markers. Some of the players to
maintain their market position in cell analysis are following inorganic strategies by acquiring
small-scale or specialized companies to access specific technology or products and that
may reduce the competitive intensity in the market to some extent. For instance, in April
2020, Bio-Rad Laboratories, Inc. acquired Celsee, Inc., which offers instruments and
consumables for the isolation, detection, and analysis of single cells. The acquisition will

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extend the company’s reach into the rapidly growing world of precision medicine and single-
cell analysis. Similarly, Agilent Technologies has acquired BioTek Instruments in August
2019, for bolstering its portfolio further with cell imaging systems, microplate readers,
washers, dispensers, automated incubators and stackers. The combined portfolio will allow
Agilent to deliver a range of unique cell analysis workflows to provide customers the ability to
obtain deeper, more reliable insights across a variety of cell analysis applications and
expand the company’s capabilities in the cell analysis market.

Major players in the cell analysis market include Agilent Technologies, Inc. (U.S.), Becton
Dickinson and Company (U.S.), Illumina Inc. (U.S.), Bio-Rad Laboratories (U.S.), Danaher
Corporation (U.S.), Merck KGaA (Germany), Olympus Corporation (Japan), PerkinElmer,
Inc. (U.S.), Promega Corporation (U.S.), Qiagen N.V. (Netherlands), and Thermo Fisher
Scientific, Inc. (U.S.).

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Cell Analysis Global Market

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Reasons for buying this report:

 Cell Analysis global market is expected to reach $33,542.0 million by 2027 growing
at mid single-digit CAGR from 2020 to 2027.
 Identification and analysis of the cell analysis market segments by- techniques,
products, applications, end-users, and geography.
 Analysis of the global market by identifying various sub-segments of the cell analysis
market.
 Revenue forecast of the cell analysis market and strategic analysis of each
submarket for individual growth trends.
 Revenue forecast of the cell analysis market for North America (U.S. and Rest of
N.A.), Europe (Germany, France, Italy and Rest of Europe), Asia-Pacific (Japan,
China, India and Rest of APAC) and RoW (Brazil, Rest of Latin America, and the
Middle East & Others) regions.
 Identification of the major market trends and factors driving or inhibiting the growth of
the cell analysis global market and its various sub-markets.
 Analysis of the opportunities for stakeholders by identifying the high-growth
segments of the market.
 Porter’s analysis, funding scenario, technological advancements, and deals
(Collaboration, agreements, Partnership, Acquisition).
 Profiles of major players in the cell analysis with details of their product offerings,
business strategies, SWOTs.

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Cell Analysis Global Market

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FIGURE 1

CELL ANALYSIS GLOBAL MARKET SEGMENTATION

Cell Analysis Global Market

By Techniques By Products Application End User

Hospitals &
PCR Consumables By Process By Field By therapeutic area Diagnostic Labs

Academic and
Sequencing Instruments Forensics
Cellular processes Cancer research research institutes
Microfluidics &
Microarrays Software and Therapeutics Infectious disease CRO’s
Services Signal Transduction

Spectrometry Genetic testing Pharmaceuticals &

Genomic analysis
CTC Biotech
Microscopy Stem cell analysis Immunology
Cell banks
Single cell analysis
Cytometry Biomarker Others
research Others
Epigenetic
HCS
Cell imaging
Sub population
Electrophoresis characterization
Diagnostics
Drug & candidate
Others screening

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