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Guideline Toolkit
for Pharmacists
Nearly half of American adults have high blood
pressure, but you can make a difference.
8 Things to Know
From the 2017 Hypertension Guideline that Will Impact Pharmacy
1 6
Blood pressure classifications have Medicine can help control high
changed. The guideline establishes a new blood pressure when lifestyle
evidence-based classification of BP in adults, with changes are not enough. Pharmacists
hypertension defined by systolic and diastolic BPs should discuss the importance of medication
that are lower than the previous thresholds. management and all prescription and over-the-
counter medications with patients.
2
The prevalence of hypertension
7
in America is higher. Nearly half of Four drug classes are recommended
all adults in the United States will have high BP as first choice for patients with high
under the updated classifications. blood pressure. They are thiazide diuretics,
calcium channel blockers, angiotensin
3
Treating high blood pressure begins converting enzyme inhibitors and angiotensin
with accurate measurements. receptor blockers. For many adults with high
Accurate measurement of BP is essential blood pressure, pharmacotherapy requires
for categorizing BP, determining the risk of more than one agent or a combination of BP
atherosclerotic cardiovascular disease and medicines.
managing high BP. Diagnosis and management
8
of hypertension should be based on accurate Improving treatment and control of
measurements not only in a doctor’s office but hypertension may require special
also through self-monitoring. consideration. Most adults receiving
antihypertensive drug therapy have an
4
High BP could be the result of a average systolic BP and/or diastolic BP
secondary cause. Secondary causes above the target level recommended in this
are responsible for about 10% of high blood guideline. Recommendations to improve
pressure cases. Many of these can either be treatment and control are provided for high
cured or require specific treatments. blood pressure in adults with one or more
comorbidities, or those who have resistant
5
Lifestyle changes are a first line hypertension or a hypertensive crisis.
of treatment for many patients.
Nonpharmacologic interventions aimed at
addressing poor dietary habits, physical inactivity Dispensing Advice
and/or excessive consumption of alcohol are
fundamentally important in managing the Top 10 Things to Know
underlying causes of high BP in most adults.
Dispensing Advice
Educate clients about the Hypertension, the “silent
importance of taking medicines as killer,” is associated with
prescribed and overall medicine a variety of life-threatening
management as a way to prevent diseases or conditions.
these consequences.
3
A SOLUTION
Knowledge
Is Power
Educate your clients about the
latest high blood pressure guideline.
Encourage them to regularly check
their blood pressure. Tell them that
high BP is treatable. Make sure
clients are aware:
Several modifiable CVD risk factors are commonly found In addition, several
in people with hypertension, including: relatively fixed risk
factors associated with
Current cigarette smoking, secondhand smoke hypertension should be
considered, including:
Diabetes mellitus • Chronic kidney disease
• Family history
Dyslipidemia/hypercholesterolemia
• Increased age
Alcohol consumption
Dispensing Advice
Help your clients
understand the risks
of high BP and the
substantial benefits
of lowering their BP.
Emphasize the central
role they play in
Nearly half of American adults have
preventing and
high blood pressure. managing elevated BP.
5
RISK FACTORS
Dispensing Advice
Help your clients understand their BP readings. Print this table, circle their BP
category, and give it to them along with other appropriate resources. The table is
available in English, Spanish and Traditional Chinese.
Measuring BP
Accurate measurement of BP is essential to The guideline describes six key steps
proper prevention, detection and management of for proper measurement of BP.
BP. Although measurement of BP seems relatively
easy, errors are common and can result in a
misleading estimation of an individual’s true STEPS FOR ACCURATE BP MEASUREMENT
level of BP and impact treatment. Recognizing 1
4 5 6
of physicians, nurses, physician assistants and RECORD SBP AND DBP**. NOTE
TIME OF MOST RECENT BP MED
TAKEN BEFORE MEASUREMENT.
USE AN AVERAGE OF 2 READINGS
OBTAINED ON 2 OCCASIONS TO ESTIMATE
THE INDIVIDUAL’S LEVEL OF BP.
PROVIDE PATIENT THE
SBP/DBP READINGS BOTH
VERBALLY AND IN WRITING.
pharmacists can have the greatest impact on AHA recommended blood pressure levels
improving the monitoring and management of LEARN MORE AT
HEART.ORG/HBPROUTINE
BLOOD PRESSURE CATEGORY
NORMAL
SYSTOLIC mm Hg
(upper number)
LESS THAN 120 and
DIASTOLIC mm Hg
(lower number)
LESS THAN 80
130-139
and
or
LESS THAN 80
80-89
American Heart Association’s efforts to improve HIGH BLOOD PRESSURE
140 OR HIGHER or 90 OR HIGHER
healthy choices related to living with high blood (HYPERTENSION) STAGE 2
pressure is proudly supported by TYLENOL®.
7
MEASURING AND MONITORING BP
Self-Monitoring
Patient self-monitoring of BP is an important focus of the 2017
guideline. It can help confirm the diagnosis of high BP. It also
can help health care providers determine whether treatments are
working. Patient training should be done under medical supervision,
with focus on evaluating the device used in the home and providing
detailed instructions for proper measurement.
The American
Be still. Don’t smoke, drink caffeinated beverages or exercise
within 30 minutes before measuring your blood pressure. Heart Association
recommends an
Sit correctly. Sit with your back straight and supported (on a automatic, cuff-style,
dining chair, rather than a sofa). Your feet should be flat on the bicep (upper arm)
floor and legs uncrossed. monitor.
Primary
aldosteronism
(8-20%)
Renovascular Drugs
disease or alcohol*
(5-34%) (2-4%)
Obstructive Renal
sleep apnea parenchymal
(25-50%) disease
(1-2%)
Common Causes of
Secondary Hypertension
*such as sodium containing antacids, caffeine, nicotine, NSAIDS, oral contraceptives and others
9
IDENTIFYING BP RAISERS
that your patients should avoid, limit or Many things can affect your blood pressure (BP). It is critical to understand what medications
and substances you should avoid to support a healthy BP.
stop to help maintain a healthy BP. SMALL CHANGES CAN MAKE A BIG DIFFERENCE
Be your own health advocate by following a healthy lifestyle, such as reducing sodium
and checking your blood pressure as part of your daily routine.
High blood pressure – a systolic blood pressure reading of 130 mmHg and above or a diastolic
reading of 80 mmHg and above – is a serious health condition that can increase your risk of
heart disease and stroke. Take these steps to control your risk.
Chronic pain affects more adults than coronary
heart disease, diabetes and cancer combined. AVOID:
• Illicit and recreational drugs
TALK TO YOUR HEALTHCARE
PROVIDER ABOUT STARTING,
As a result, the use of pain relievers is common. • Herbal supplements STOPPING OR CHANGING:
• Foods that contain tyramine when • NSAID pain medication (drugs like
taking antidepressants, such as MAOIs acetaminophen are less likely to increase BP)
flow and cause sodium retention. Clients older 2 drinks a day for men
• Caffeine to less than 300 mg per day
• Certain cancer medications
(such as angiogenesis inhibitors)
(about 2-3 cups of coffee); avoid with
than 65 years are at most risk for this effect. For hypertension
• Decongestants and some cold
medicines; avoid with severe or
NOTE: Do you suffer from chronic pain? Certain
medicines can raise your BP or make your BP
medication less effective. Talk to your healthcare
when selecting medications for pain relief. Certain American Heart Association’s efforts to improve healthy choices related
to living with high blood pressure is proudly supported by TYLENOL®.
heart.org/bptools
© 2018 American Heart Association, Inc., All rights reserved.
Dispensing Advice
Encourage your clients to talk openly
about which over-the-counter medicines
and substances they consider using.
Print the list of medications and
substances shown above, create
an encouraging environment and start
the conversation with your clients.
Encourage clients with elevated BP or
hypertension to consider using pain
relievers other than NSAIDs, depending
on the indications and risks.
Nonpharmacological Interventions
Guideline-recommended treatment includes Nonpharmacologic Interventions
nonpharmacologic interventions for patients with The guideline recommends several
elevated BP or stage 1 hypertension and an nonpharmacologic interventions
estimated 10-year CVD risk of less than 10%. that have been shown to reduce systolic BP
by as much as 11 mm Hg in adults with
A combination of antihypertensive medication hypertension. These interventions also can help
and nonpharmacologic interventions is prevent hypertension in adults with normal BP.
recommended for patients with stage 1
hypertension and an estimated 10-year • Weight loss for patients who are
ASCVD risk of 10% or higher and for all overweight or obese
patients with stage 2 hypertension. • Heart-healthy diet (such as DASH)
• Sodium reduction
• Potassium supplementation (preferably in
Dispensing Advice dietary modification)
• Increased physical activity with structured
Talk to your patients about the exercise program
benefits of lifestyle changes in • Limitation of alcohol to one (women)
reducing BP. Give them the “What or two (men) standard drinks per day*
Can I Do To Improve My Blood *In the United States, one “standard” drink contains
roughly 14 g of pure alcohol, which is typically found in
Pressure” resource as a reminder 12 ounces of regular beer (usually about 5% alcohol),
5 ounces of wine (usually about 12% alcohol) and 1.5
for them at home. ounces of distilled spirits (usually about 40% alcohol).
Pharmacological Interventions
Antihypertensive Medication
The BP threshold for antihypertensive medication Several different BP thresholds and goals for
should be determined based on the average BP the long-term treatment of hypertension with
levels and CVD risk. pharmacological therapy are recommended in
the guideline. Use this quick reference for a
BP Threshold Patient summary.
(mm Hg) Scenario
Initiation of antihypertensive drug therapy with
≥130/80 ASCVD risk
a single antihypertensive drug is reasonable in
of 10% or higher
adults with stage 1 hypertension and BP goal
OR
Clinical CVD <130/80 mm Hg with dosage titration and
sequential addition of other agents to achieve the
≥140/90 ASCVD risk
BP target. (COR IIa, LOE C-EO)
less than 10%
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TREATMENTS
Follow-up visits to reassess BP and monitor adherence and response to treatment should be
regularly scheduled according to guideline recommendations. Use of self-monitoring, team-based
care and telehealth strategies is recommended.
The guideline also includes several recommendations for specific antihypertensive medications
according to these comorbidities as well as others, such as acute intracerebral hemorrhage,
atrial fibrillation, valvular heart disease and aortic disease.
Resistant Hypertension
Studies have found that patients with resistant hypertension are at high risk for cardiovascular
complications. The prevalence of resistant hypertension has been identified as anywhere from
3%-30% of patients who required at least three or more medications to reach blood pressure
control. The guideline defines treatment resistance and offers recommendations for evaluating
and treating patients.
Algorithm for Diagnosis, Evaluation and Treatment
13
SPECIAL PATIENT GROUPS AND EMERGENCIES
For patients with hypertension and a high burden of comorbidity and limited life expectancy, clinical
judgment, patient preferences and a team-based approach should be used to assess risk/benefit for
decisions regarding intensity of BP lowering and choice of antihypertensive medications.
Only 1 in 5
pressure. Encourage the use of strategies
that can help promote necessary behavioral
changes such as the following:
patients has sufficiently high adherence
• Set goals. to achieve the benefits observed in clinical trials.
• Provide feedback.
Research has shown that as many as 25% of
• Emphasize importance patients do not fill their initial prescription for
of self-monitoring. antihypertensive therapy. Use strategies that
• Promote self-sufficiency. have been found to be effective in
improving adherence, such as the
• Schedule consistent follow-up.
following:
• Use motivation interventions.
• Educate patients about hypertension, its
These strategies are most effective consequences and potential side effects of
when combined. medication.
• Collaborate with patients to establish goals of
therapy and plan of care.
• Prescribe medication as once-daily dosing
Dispensing Advice • Integrate pill-taking into routine activities
of daily living with support tools such as
Consider the cultural and social
reminders, pillboxes, packaging and other
contexts and health literacy of your aids.
clients. Create an encouraging, • Use fixed-dose combination agents when
blame-free environment. Talk openly available.
about expectations and goals. Listen • Use medication adherence scales to facilitate
to their concerns. Answer their identification of barriers.
• Recognize patients for achieving treatment
questions.
goals.
15
Helpful Links and Other Resources
Here are some AHA tools and resources to help with client education.
They have been developed with guidance from AHA volunteers who face
the same challenges as your clients.
www.heart.org/bp
Patient Resources
Blood Pressure Fact Sheets
© Copyright 2020 American Heart Association, Inc., a 501(c)(3) not-for-profit. All rights reserved. Unauthorized use prohibited.