Project 2.1.

1 Scientific Research
Conclusion Questions:
Answer the questions below in complete sentences make sure to make your text
bold and italicized so I can distinguish your answer from the question.

1. What should the coach have done differently to ensure validity?

2. Follow the links below to read the abstracts from two scientific journals. For each
abstract describe which type of study design was used and explain how you
arrived at your answer.
 Green R, Schneider L, Amato D, Beelen A, Wilcock G, Swabb E, Zavitz K. 2009.
Effect of Tarenflurbil on cognitive decline and activities of daily living in patients
with mild Alzheimer disease. J Am Med Assoc [Internet]. [cited 2009 Dec 21];
302(23): 2557-2564. Available from http://jama.ama-
assn.org/cgi/content/abstract/302/23/2557

 Schulman S, Kearon C, Kakkar A, Mismetti P, Schellong S, Eriksson H, Bannstra

D, Schnee J, Goldhaber S. 2009. Dabigatran versus Warfarin in the treatment of
acute venous thromboembolism. N Engl J Med [Internet]. [cited 2009 Dec 21];
361(24):2342-2352. Available from
http://content.nejm.org/cgi/content/abstract/361/24/2342

© 2011 Project Lead The Way, Inc.

Biomedical Innovation Project 2.1.1 Scientific Research – Page 1
1. Which type of study design would be the most appropriate to test the relationship
between your chosen pair? Explain your answer.

2. What are some of the potential biases and confounding variables in your study
design? How have you set up your study to reduce or eliminate these potential
biases and confounding variables?

3. Will your study test for a correlation or causal relationship between the activity
and disease? Explain your answer.

© 2011 Project Lead The Way, Inc.

Biomedical Innovation Project 2.1.1 Scientific Research – Page 2