DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING

EFFECTS RESPONSIBILITIES

Drug Name: Phenelzine is an  Depression  Hypersensitivity to  Sedation  Assess for expected

- Nardil antidepressant. This  Anxiety Nardil  Edema effects
medication treats  Phobic  Congestive heart  Substantial weight  Recognize side
Generic Name: depression by restoring  Hypochondriacal failure gain effects and adverse
-Phenelzine sulfate the balance of certain   Severe renal  Elevated liver effects
natural substances in impairment function tests  Therapeutic drug
Classification: the brain. Phenelzine  Liver disease  Hepatocellular monitoring
-Monoamine oxidase can improve your  Abnormal liver damage  Assess for
inhibitors mood and feelings of function tests  Liver failure undiagnosed
well being. Usually this  illnesses
Patient taking  Dry mouth
Dosage: medication is used in sympathomimetic  Teach patients that
 Nausea, diarrhea
15 mg persons who have not drugs therapy is long term
or constipation
responded to treatment and lifelong
 Patient taking CNS  Headache
Route: with other drugs.  Check vital signs
depressant  Drowsiness
- PO
 Insomnia
Frequency:  Dizziness or
- TID lightheadedness
 Skin reaction at the
patch site

DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING

EFFECTS RESPONSIBILITIES
Drug Name: It is a monoamine  Depression  Hypersensitivity to  Lower the effect of  Assess for expected
- Marplan oxidase inhibitor. It is  Delusions medication psychotic effects
used in the treatment  anxiety  Congestive heart  Sedation  Recognize side
Generic Name: of major depression, failure  Edema effects and adverse
-Isocarboxazid dysthymic disorder,  Severe renal  Substantial weight effects
atypical disorder, panic impairment gain  Therapeutic drug
Classification: disorder and the  Liver disease  Elevated liver monitoring
-Monoamine oxidase phobic disorders.  Abnormal liver function tests  Assess for
inhibitors function tests  Hepatocellular undiagnosed
 Patient taking damage illnesses
Dosage:  Teach patients that
sympathomimetic  Liver failure
- 10 mg/1 drugs therapy is long term
 Dry mouth
 Patient taking CNS  Nausea, diarrhea and lifelong
Route:  Check vital signs
depressant or constipation
- PO
 Headache
Frequency:  Drowsiness
- TID  Insomnia
 Dizziness or
lightheadedness
 Skin reaction at the
patch site

DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING

EFFECTS RESPONSIBILITIES
Drug Name: It is a monoamine  Depression  Hypersensitivity to  Sedation  Assess for expected
- Emsam oxidase inhibitor. It is  Delusions medication  Edema effects
used in the treatment anxiety  Congestive heart  Substantial weight  Recognize side
Generic Name: of major depression, failure gain effects and adverse
-Selegiline dysthymic disorder,  Severe renal  Elevated liver effects
atypical disorder, panic impairment function tests  Therapeutic drug
Classification: disorder and the  Liver disease  Hepatocellular monitoring
-Monoamine oxidase phobic disorders.  Abnormal liver damage  Assess for
inhibitor function tests  Liver failure undiagnosed
 Patient taking  Dry mouth illnesses
Dosage: sympathomimetic  Teach patients that
 Nausea, diarrhea
- 6,9,12 mg drugs therapy is long term
or constipation
Patient taking CNS  Headache and lifelong
Route: depressant  Check vital signs
-Transdermal  Drowsiness
 Insomnia
Frequency:  Dizziness or
- TID lightheadedness
 Skin reaction at the
patch site
DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING
EFFECTS RESPONSIBILITIES

Drug Name: It is a monoamine  Depression  Hypersensitivity to  Sedation  Assess for expected

- Parnate oxidase inhibitor. It is  Delusions medication  Edema effects
used in the treatment anxiety  Congestive heart  Substantial weight  Recognize side
Generic Name: of major depression, failure gain effects and adverse
-Tranylcypromine dysthymic disorder,  Severe renal  Elevated liver effects
atypical disorder, panic impairment function tests  Therapeutic drug
Classification: disorder and the  Liver disease  Hepatocellular monitoring
-Monoamine oxidase phobic disorders.  Abnormal liver damage  Assess for
inhibitor function tests  Liver failure undiagnosed
 Patient taking  Dry mouth illnesses
Dosage: sympathomimetic  Teach patients that
 Nausea, diarrhea
- 10 mg drugs therapy is long term
or constipation
Patient taking CNS  Headache and lifelong
Route: depressant  Check vital signs
-PO  Drowsiness
 Insomnia
Frequency:  Dizziness or
- TID lightheadedness
 Skin reaction at the
patch site
DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING
EFFECTS RESPONSIBILITIES

Drug Name: Inhibits the reuptake of  Depression  Hypersensitivity to  Nausea, vomiting  Administer once a
- Celexa serotonin in  Delusions medication or diarrhea day, in the morning;
presynaptic neurons,  Anxiety  Renal impairment  Headache may be taken with
Generic Name: little or no affinity for  Suicidal thoughts  Methylene blue  Drowsiness food if desired.
-Citalopram dopamine, alpha  Panic attack therapy  Dry mouth  Encourage patient to
adrenergic histamine,  Trouble sleeping  Taking another  Insomnia continue use for 4–6
Classification: or cholinergic antidepressant  week, as directed, to
 Impulsive actions Nervousness,
-Selective serotonin receptors. medication agitation or ensure adequate
 Very rapid speech
reuptake inhibitors restlessness levels to affect
 Dizziness depression.
Dosage:  Limit amount of drug
 Sexual problems,
- 20 mg-40mg given in prescription
such as reduced
sexual desire, to potentially suicidal
Route: patients.
difficulty reaching
-PO  Establish
orgasm or inability
to maintain an appropriate safety
Frequency: precautions if patient
erection (erectile
- OD experiences adverse
dysfunction)
 Impact on appetite, CNS effects.
leading to weight  Institute appropriate
loss or weight gain therapy for patient
suffering from
depression
DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING
EFFECTS RESPONSIBILITIES

Drug Name: Inhibits the reuptake of  Depression  Hypersensitivity to  blurred vision,  Administer once a
- Lexapro serotonin in  Delusions medication  tunnel vision, day, in the morning;
presynaptic neurons,  Anxiety  Renal impairment  eye pain or may be taken with
Generic Name: little or no affinity for  Suicidal thoughts  Methylene blue swelling, food if desired.
-Escitalopram dopamine, alpha  Panic attack therapy  seeing halos  Encourage patient to
adrenergic histamine,  Trouble sleeping  Taking another around lights, continue use for 4–6
Classification: or cholinergic antidepressant  racing thoughts, week, as directed, to
 Impulsive actions
-Selective serotonin receptors. medication  unusual risk-taking ensure adequate
 Very rapid speech
reuptake inhibitors behavior, levels to affect
 headache, depression.
Dosage:  Limit amount of drug
 confusion,
- 5 mg-20mg given in prescription
 slurred speech,
to potentially suicidal
Route:  severe weakness,
patients.
-PO  vomiting,
 Establish
 loss of
appropriate safety
Frequency: coordination,
precautions if patient
- OD  feeling unsteady, experiences adverse
 very stiff (rigid) CNS effects.
muscles,  Institute appropriate
 high fever, therapy for patient
 sweating, suffering from
 confusion, depression
 fast or uneven
heartbeat,
 tremors, and
 lightheadedness
DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING
EFFECTS RESPONSIBILITIES

Drug Name: Inhibits the reuptake of  Symptoms of  Hypersensitivity to  Nausea  Administer once a
- Zoloft serotonin in depression medication  Loose stools day, in the morning;
presynaptic neurons,  Mania  Renal impairment  Dyspepsia may be taken with
Generic Name: little or no affinity for  Obsessive  Methylene blue  Dizziness food if desired.
-Sertraline dopamine, alpha  Compulsive therapy  Insomnia  Encourage patient to
adrenergic histamine, disorder  Taking another  Somnolence continue use for 4–6
Classification: or cholinergic antidepressant week, as directed, to
 Dry mouth
-Selective serotonin receptors. medication ensure adequate
 Increased sweating
reuptake inhibitors levels to affect
 Erectile dysfunction
depression.
Dosage:  Limit amount of drug
- 50 mg given in prescription
to potentially suicidal
Route: patients.
-PO  Establish
appropriate safety
Frequency: precautions if patient
- OD experiences adverse
CNS effects.
 Institute appropriate
therapy for patient
suffering from
depression
DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING
EFFECTS RESPONSIBILITIES

Drug Name: The antidepressant  Depression  Hypersensitivity to  blurred vision,  Monitor patient with
- Anafranil effects of clomipramine  Obsessive medication  dry mouth, history of CVD
are thought to be due  Compulsive  Severe  constipation,  Monitor BP, pulse
Generic Name: to reuptake inhibition of syndrome cardiovascular  weight gain or loss, every 4 hrs, if
-Clomipramine serotonin and  Phobias disorder  low blood pressure systolic BP drops 20
norepinephrine, while  Panic attacks  Narrow angle on standing, mmHg hold drugs
Classification: serotonin reuptake glaucoma  rash,  Monitor blood
-Tricyclic inhibition only is  Drugs that prolong studies
 hives, and
antidepressants thought to be QT interval  Assess mental
 increased heart
responsible for the  Acute recovery status
rate.
Dosage: effectiveness of post-heart
- 100-200 mg clomipramine in the  Co-administration
treatment of OCD. with serotonergic
Route: drugs
-PO
 Lactation
 Pregnancy
Frequency:
- OD
DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING
EFFECTS RESPONSIBILITIES

Drug Name: The antidepressant  Depression  Hypersensitivity to  Sedation  Monitor patient with
- Norpramine effects of clomipramine medication  Anxiety history of CVD
are thought to be due  Myocardial  Insomnia  Monitor BP, pulse
Generic Name: to reuptake inhibition of infarction  Delusions every 4 hrs, if
-Desipramine serotonin and  MAO inhibitors  Agitation systolic BP drops 20
norepinephrine, while used within past 14  Hallucinations mmHg hold drugs
Classification: serotonin reuptake days  Monitor blood
 Hypotension
-Tricyclic inhibition only is studies
 Hypertension
antidepressants thought to be  Assess mental
responsible for the  Tachycardia
 Disorientation status
Dosage: effectiveness of
- 75-300 mg clomipramine in the
treatment of OCD.
Route:
-PO

Frequency:
- OD
DRUG NAME MODE OF ACTION INDICATION CONTRAINDICATION SIDE/ADVERSE NURSING
EFFECTS RESPONSIBILITIES

Drug Name: The antidepressant  Depression  Hypersensitivity to  Anxiety  Monitor patient with
- Norpramine effects of clomipramine  Hallucination medication  Insomnia history of CVD
are thought to be due  Myocardial  Restlessness  Monitor BP, pulse
Generic Name: to reuptake inhibition of infarction  Palpitations every 4 hrs, if
-Desipramine serotonin and  MAO inhibitors  Alteration of EEG systolic BP drops 20
norepinephrine, while used within past 14 patterns mmHg hold drugs
Classification: serotonin reuptake days  Edema  Monitor blood
-Tricyclic inhibition only is studies
 Skin rash
antidepressants thought to be  Assess mental
 Nausea
responsible for the status
Dosage: effectiveness of  Fatigue
- 200-300 mg clomipramine in the  Dizziness
treatment of OCD.  Headache
Route:  Increased
-PO perspiration
 Weakness
Frequency:  Excessive appetite
- OD