Professional Documents
Culture Documents
Inflation Chart
(A) 146
(B) 149
(C) 154
(D) 157
(E) 165
1) In 2013, the dollar amount of the profit at
QN Corporation was approximately which of the
following?
2) For the students in this trial with the three
highest scores, approximately what is the
(A) $80 million
average number of hours they spend
studying? (B) $160 million
(C) $190 million
(A) 29 (D) $240 million
(B) 32 (E) $350 million
(C) 35
(D) 39
(E) 43
2) From 2010 to 2015, revenue at QN 3) From 2009 to 2010, profit at QN Corporation
Corporation increased by approximately what increased by approximately what percent?
percent?
(A) 81%
(A) 18% (B) 165%
(B) 47% (C) 300%
(C) 63% (D) 433%
(D) 84% (E) 533%
(E) 126%
PART A.
The symptoms of COVID-19 infection appear after an incubation period of approximately 5.2 days (17). The period from
the onset of COVID-19 symptoms to death ranged from 6 to 41 days with a median of 14 days. This period is dependent on
the age of the patient and status of the patient's immune system and was shorter among patients >70-years old (13). The
most common symptoms at onset of COVID-19 illness are fever, cough, and fatigue, followed by sputum production,
headache, haemoptysis, diarrhea and dyspnea (13,16,18,19). Clinical features reveal pneumonia with abnormal features such
as acute respiratory distress syndrome and acute cardiac injury that lead to death (19).
80+
10-19
10-19
15%
1. Which group has a higher death rate, 19-year olds with the COVID-19 or 70-year olds with the
flu?
2. Which virus has a higher maxiumum death rate, COVID-19 or the Flu?
COVID-19
0.2%
0.01%
0.01%
0.2%
Corona Virus
Chicken Pox
Spanish Flu, SARS, Seasonal Flu, Polio, Common Cold, Ebola, Bird Flu
PART B.
In less than a month, the global number of confirmed COVID-19 cases doubled from about 75,000
cases on Feb. 20 to more than 153,000 on March 15. That infection rate, scary as it sounds, hides
just how much the out-of control virus has spread, especially in the hardest-hit communities. In Italy,
for example — the country with the worst COVID-19 outbreak outside of China — confirmed cases
doubled from 10,000 to 20,000 in just four days (March 11 to March 15).
This rapid growth rate in Italy has already filled some hospitals there to capacity, forcing emergency
rooms to close their doors to new patients, hire hundreds of new doctors and request emergency
supplies of basic medical equipment, like respirator masks, from abroad. This lack of resources
contributes, in part, to the outsize COVID-19 death rate in Italy, which is roughly 7% — double the
global average, PBS reported.
Health officials take for granted that COVID-19 will continue to infect millions of people around the
world over the coming weeks and months. However, as the outbreak in Italy shows, the rate at
which a population becomes infected makes all the difference in whether there are enough hospital
beds (and doctors, and resources) to treat the sick.
In epidemiology, the idea of slowing a virus' spread so that fewer people need to seek treatment at
any given time is known as "flattening the curve." It explains why so many countries are
implementing "social distancing" guidelines — including a "shelter in place" order that affects 6.7
million people in Northern California, even though COVID-19 outbreaks there might not yet seem
severe. Here's what you need to know about the curve, and why we want to flatten it.
The curve takes on different shapes, depending on the virus's infection rate. It could be a steep
curve, in which the virus spreads exponentially (that is, case counts keep doubling at a consistent
rate), and the total number of cases skyrockets to its peak within a few weeks. Infection curves with
a steep rise also have a steep fall; after the virus infects pretty much everyone who can be infected,
case numbers begin to drop exponentially, too.
The faster the infection curve rises, the quicker the local health care system gets overloaded
beyond its capacity to treat people. As we're seeing in Italy, more and more new patients may be
forced to go without ICU beds, and more and more hospitals may run out of the basic supplies they
need to respond to the outbreak.
A flatter curve, on the other hand, assumes the same number of people ultimately get infected, but
over a longer period of time. A slower infection rate means a less stressed health care system,
fewer hospital visits on any given day and fewer sick people being turned away.
For a simple metaphor, consider an office bathroom. "Your workplace bathroom has only so many
stalls," Charles Bergquist, director of the public radio science show "Science Friday" tweeted. "If
everyone decides to go at the same time, there are problems. If the same number of people need
go to the restroom but spread over several hours, it's all ok."
QUESTIONS:
1. Why is socially distancing important? Support your reasoning with data and information from the
figures and text.
Socially distancing is important because it limits the spread of the virus. This is shown in the graph
for the Spanish Flu. On one hand, St. Louis took precautions, social distanced and limited travel
while on the other hand, Philadelphia, did the opposite. They didn’t social distance and ignored all
the warnings, therefore, their death rates were five times more than St. Louis. St. Louis had 2,000
deaths while Philadelphia saw about 16,000 deaths in just 6 months.
2. “The curve takes on different shapes, depending on the virus's infection rate. It could be a steep
curve, in which the virus spreads exponentially (that is, case counts keep doubling at a consistent rate),
and the total number of cases skyrockets to its peak within a few weeks. Infection curves with a steep
rise also have a steep fall; after the virus infects pretty much everyone who can be infected, case
numbers begin to drop exponentially, too.”
Based on the above information, what will “flattening” the curve shorten or lengthen the amount of
time it takes for the virus to infect everyone who can be infected and cases begin to drop?
It will take more time since the virus is progressing slowly, not like in the beginning as it is not
infecting people as rapidly when the curve was rising exponentially. Almost everyone is going to be
infected by the virus and then eventually the curve will slow down exponentially.
3. How many people died in Philadelphia during the Spanish flu pandemic of 1918?
About 16,000
4. How many people died in St. Louis during the Spanish flu pandemic of 1918?
2,000
They were so different as different precautions were taken. On one hand, St. Louis took
precautions, social distanced and limited travel while on the other hand, Philadelphia, did the
opposite. They didn’t social distance and ignored all the warnings, therefore, their death rates were
five times more than St. Louis. St. Louis had 2,000 deaths while Philadelphia saw about 16,000
deaths in just 6 months.
6. The number of deaths in Philadelphia was close to 0 by November of 1918, meaning the worst of
the virus was over, whereas St. Louis took much longer to see deaths reach close to zero. Explain
why taking longer was actually better.
St. Louis was taking longer to actually get better because the virus progressed slowly as they social
distanced and took effective precautions and therefore it will also decrease slowly because it took
more time for the people to get the virus than the people in Philadelphia. Philadelphia had high
exponential growth of the virus, meaning that the virus spread at a very fast rate and therefore
everyone either survived the virus or died from it and that’s why they reached the zero faster that
St. Louis.
PART C.
Article reference: Gautret et al. (2020) Hydroxychloroquine and azithromycin as a treatment of COVID‐19:
results of an open‐label non‐randomized clinical trial. International Journal of Antimicrobial Agents – In Press
17 March 2020 – DOI : 10.1016/j.ijantimicag.2020.105949
Scientists throughout the globe are currently working to develop treatments and vaccines for
COVID-19. One treatment that is showing promising results is the use of an antimalarial drug called
Hydroxychloroquine. Researchers just completed a study investigating the effectiveness of these
drugs in treating COVID-19.
Gautret et al. gave hydroxychloroquine to 20 patients who had COVID-19. They then monitored
these patients symptoms. They also monitored 16 patients who had COVID-19 but did not receive
hydroxylchloroquine. They ran statistical tests to compare the recovery of patients and found a
significant difference between those treated with hydroxychloroquine and those not treated:
Percentage of patients still testing positive for COVID19
1. Based on the figure, was the hypothesis supported?
Yes, there was a significant difference between the experimental and control group. This
showed a positive progress in the experimental group, showing the effectiveness of the drug
hydroxychloroquine and therefore, supporting the hypothesis.
2. On day 6, what percentage of patients treated with Hydroxychloroquine still tested positive
for COVID-19?
30%
3. One day 6, what percentage of patients not treated with Hydroxychloroquine still tested
positive for COVID-19?
About 90%
4. We now know that Hydroxychloroquine is not an effective treatment for covid-19. Discuss a
potential explanation for this study determining there is an effect of hydroxychloroquine on
Covid-19 illness when the effect doesn’t actually exist.
The placebo effect. Convincing the patients that this treatment will heal them from the
corona virus.