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What is stress?
Stress can be defined as the brain’s response to any demand. Many things can trigger this response, includ-
ing change. Changes can be positive or negative, as well as real or perceived. They may be recurring, short-
term, or long-term and may include things like commuting to and from school or work every day, traveling for
a yearly vacation, or moving to another home. Changes can be mild and relatively harmless, such as winning
a race, watching a scary movie, or riding a rollercoaster. Some changes are major, such as marriage or
divorce, serious illness, or a car accident. Other changes are extreme, such as exposure to violence, and can
lead to traumatic stress reactions.
Where can I find more information Information from NIMH is available in multiple
formats. You can browse online, download
about stress? documents in PDF, and order materials through
Visit the National Library of Medicine’s the mail. Check the NIMH website at http://www.
MedlinePlus at http://medlineplus.gov nimh.nih.gov for the latest information on this
En Español, http://medlineplus.gov/spanish topic and to order publications. If you do not
have Internet access, please contact the NIMH
For information on clinical trials: Information Resource Center at the numbers
NIMH supported clinical trials listed below.
http://www.nimh.nih.gov/health/trials/ National Institute of Mental Health
index.shtml Science Writing, Press, and Dissemination Branch
National Library of Medicine 6001 Executive Boulevard
U.S. Department of Health
and Human Services Clinical Trials Database Room 8184, MSC 9663
National Institutes of Health http://www.clinicaltrials.gov Bethesda, MD 20892-9663
Clinical trials at NIMH in Bethesda, MD Phone: 301-443-4513 or
http://patientinfo.nimh.nih.gov 1-866-615-NIMH (6464) toll-free
TTY: 301-443-8431 or
1-866-415-8051 toll-free
Fax: 301-443-4279
E-mail: nimhinfo@nih.gov
Website: http://www.nimh.nih.gov
The photo in this publication is of a model and is used for illustrative purposes only.