Immunology

1. Phagocytes of the epidermis are called….

a. Microglia
b. Goblet cell
c. Alveolar macrophages
d. Dendritic cells
2. Mucus-secreting membranes are found in the
a. urinary system.
b. digestive cavity.
c. respiratory passages.
d. all of the above
3. The complement system involves
a. the production of antigens and antibodies.
b. serum proteins involved in nonspecific defense.
c. a set of genes that distinguish foreign cells from body cells.
d. the elimination of undigested remnants of microorganisms.
4. Which of the following is not targeted by a Toll-like receptor?
a. lipid A
b. eukaryotic flagellar protein
c. gamma interferon.
d. delta interferon.
5. Toll-like receptors (TLRs) act to
a. bind microbial proteins and polysaccharides.
b. induce phagocytosis.
c. cause phagocytic chemotaxis.
d. destroy microbial cells.
6. Which of these characteristics is not a major factor in adaptive or
acquired immunity?
a. specifi city
c. recognition
b. chemotaxis
d. memory
7. The primary B-cell receptor is
a. IgD
c. IgE
b. IgA
d. IgG
8. In humans, B cells mature in the…………and T cells mature in the……………..
a. GALT, liver
c. bone marrow, thymus
b. bursa, thymus
d. lymph nodes, spleen
9. Which type of cell actually secretes antibodies?
a. T cell
 c. plasma cell
b. macrophage
d. monocyte
10. Helper T cells receive antigen from…………and cytotoxic T cells receive antigen from………..
a. macrophages, B cells
c. viruses, bacteria
b. class II MHC,
d. class I MHC, class II MHC class I MHC
11. The cross-linkage of antigens by antibodies is known as
a. opsonization
c. agglutination
b. a cross-reaction
d. complement fi xation
12. The greatest concentration of antibodies is found in the
fraction of the serum.
a. gamma globulin
c. beta globulin
b. albumin
d. alpha globulin
13. T cells assist in the functions of certain B cells and other T cells.
a. sensitized
c. helper
b. cytotoxic
d. natural killer
14. Cytotoxic T cells are important in controlling
a. virus infections
c. autoimmunity
b. allergy
d. all of these
15. Which of the following can serve as antigen-presenting cells (APCs)?
a. T cells
b. B cells
c. macrophages
d. dendritic cells
e. b, c, and d
16. What does the rabies vaccine contain that the rabies immunoglobulin
does not?
a. antibodies
c. live virus
b. inactive virus
d. animal serum
17. What types of cells could be involved in specific immune reactions
against the rabies virus?
a. T cells
 b. B cells
c. macrophages
d. dendritic cells
e. a, b, and d
f. all of these
18. A vaccine that contains parts of viruses is called
a. acellular
c. subunit
b. recombinant
d. attenuate
19. Type II hypersensitivities are due to
a. IgE reacting with mast cells.
b. activation of cytotoxic T cells.
c. IgG-allergen complexes that clog epithelial tissues.
d. complement-induced lysis of cells in the presence of antibodies.
20. Rheumatoid arthritis is an ____ that affects the ____.
a. immunodeficiency disease, muscles
b. autoimmune disease, nerves
c. allergy, cartilage
d. autoimmune disease, joints

True-False Questions. If the statement is true, leave as is. If it false, correct it by rewriting the
sentence

1. T cells are associated with type IV allergies.

2. A positive tuberculin skin test is an example of antibody-mediated inflammation.
3. Contact dermatitis can be caused by proteins found in foods.
4. Antibody-mediated degranulation of mast cells is involved in anaphylaxis.
5. Rejection of transplanted tissue is dependent on MHC/HLA
markers.

Essay

1. Describe the structure of immunoglobulin.

2. What are the functions of the FAb and Fc portions?
3. Describe the major histocompatibility complex, and explain how it participates in immune
reactions.
4. Describe the actions of an antigen-presenting cell.