The document discusses pain pathways and different types of pain. It states that pain sensation travels from nociceptors through peripheral nerves to the dorsal root ganglia and dorsal horn of the spinal cord before crossing sides and traveling to the thalamus and post central gyrus. Tissue damage stimulates the release of prostaglandins which lower the threshold for activating C fiber nociceptors. Nociceptive pain directly damages nociceptors while neuropathic pain damages the nervous system. It also discusses common pain medications and their uses and mechanisms including acetaminophen, NSAIDs, opioids, dextromethorphan, lidocaine, gabapentin and others.
The document discusses pain pathways and different types of pain. It states that pain sensation travels from nociceptors through peripheral nerves to the dorsal root ganglia and dorsal horn of the spinal cord before crossing sides and traveling to the thalamus and post central gyrus. Tissue damage stimulates the release of prostaglandins which lower the threshold for activating C fiber nociceptors. Nociceptive pain directly damages nociceptors while neuropathic pain damages the nervous system. It also discusses common pain medications and their uses and mechanisms including acetaminophen, NSAIDs, opioids, dextromethorphan, lidocaine, gabapentin and others.
The document discusses pain pathways and different types of pain. It states that pain sensation travels from nociceptors through peripheral nerves to the dorsal root ganglia and dorsal horn of the spinal cord before crossing sides and traveling to the thalamus and post central gyrus. Tissue damage stimulates the release of prostaglandins which lower the threshold for activating C fiber nociceptors. Nociceptive pain directly damages nociceptors while neuropathic pain damages the nervous system. It also discusses common pain medications and their uses and mechanisms including acetaminophen, NSAIDs, opioids, dextromethorphan, lidocaine, gabapentin and others.