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Acute Surgical

When a patient
presents to the ED
with acute abdominal
The Basics pain, the emergency
physician’s role in taking
a history, performing
an exam, selecting the
appropriate imaging
modality, and calling for
surgical consultation,
if needed, cannot be
underestimated. The
authors review the most
common etiologies of
acute surgical abdomen
and the emergency
physician’s pivotal
responsibility in ensuring
the best outcomes.

Brian H. Campbell, MD, and Moss H. Mendelson, MD

A
bdominal pain is a common complaint depending on the capabilities of the home institu-
seen in emergency departments nation- tion. This article reviews key points in the evaluation
wide. According to the CDC, stomach of adult patients with abdominal pain, discusses dis-
and abdominal pain are the leading rea- ease processes that require emergent surgical evalu-
sons for visits to the ED, accounting for 6.8% of ation and treatment, and highlights the importance
all visits in 2006.1 An adult patient with an acute of facilitating early surgical intervention. Although
abdomen generally appears ill and has abnormal there are many causes of abdominal pain, this article
findings on physical exam. Many of these patients will focus on etiologies that often lead to an acute
need immediate surgery, as several of the underlying surgical abdomen, ie, those cases in which a patient
disease processes that result in an acute abdomen needs emergent evaluation and treatment and likely
are associated with high morbidity and/or mortal- requires emergent operative treatment.
ity. The emergency physician must rapidly identify
those patients who require early surgical interven- HISTORY
tion and appropriately resuscitate them, order the Every clinician learns that history is the key to di-
necessary tests, consult the surgical team early on, agnosing most illness, and this is especially true for
and notify surgical staff or arrange for a transfer, patients with abdominal pain. The standard ques-
tions of location, onset, frequency, quality, severity,
© 2010 Joe Gorman

Dr. Campbell is a resident in the department of radiation, exacerbating/relieving features, and pre-
emergency medicine at Eastern Virginia Medical School in vious episodes and treatments are all pertinent in
Norfolk. Dr. Mendelson is an associate professor in the
department of emergency medicine at Eastern Virginia patients presenting with abdominal pain. Additional
Medical School. questions should address nonabdominal diseases that

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ACUTE SURGICAL ABDOMEN

can present atypically with abdominal pain, such as to minimize guarding, which is a natural response
pneumonia, acute myocardial infarction, and pulmo- to significant intra-abdominal discomfort, it is ben-
nary embolism. eficial to begin palpation away from the area where
It is important to consider the stage of the pa- the patient reports that the pain is located.
tient’s disease process at the time of presentation, as Many patients with an acute surgical abdomen
symptoms can change over time. Migration of pain, have peritoneal signs, which include involuntary
for instance, can be characteristic of certain entities guarding, pain with light palpation, and rebound
or disease progression. Consider the classic presen- tenderness. Patients may also describe symptoms
tation of appendicitis, which starts as generalized suggestive of peritonitis during the history-taking
or right-sided abdominal pain and then localizes to process. These include pain elicited by walking,
McBurney’s point (one-third of the distance from the driving over bumps in the road, shaking of the bed
right anterior superior iliac spine to the umbilicus). during rest, and/or coughing. In the absence of an
With further disease progression (perhaps rupture), exam suggesting frank peritonitis, localizing the pain
pain from appendicitis may again generalize as peri- on exam can help form and narrow the differen-
tonitis develops. tial diagnosis. Furthermore, serial abdominal exams
It is also important to ask about pertinent medical should be performed, especially in patients with an
and family history, including vascular disease, hyper- uncertain diagnosis after initial evaluation. Changes
tension, coagulation disorders, collagen vascular dis- in the exam findings can narrow the differential di-
ease, previous surgeries, and history of gastrointesti- agnosis and also help determine appropriate timing
nal illnesses (including Crohn’s disease and ulcerative of treatments and/or consultations.
colitis). Social history should not be forgotten, as Additional components of the abdominal exam
alcohol and smoking can contribute to many disease include auscultation, skin exam, and several specific
processes. Patients often do not voluntarily report maneuvers. Auscultation for bowel sounds is not
illicit drug use, so the physician should specifically specific or sensitive, but absent bowel sounds may
ask about it. Muniz and Evans describe several cases suggest peritonitis and high-pitched bowel sounds
of ischemic bowel associated with recent cocaine use may support diagnosis of an obstructive process. A
that required bowel resection.2 Review of systems thorough skin exam is important, as some patients
should also include questions regarding fever, nau- will have discolorations that point to a diagnosis.
sea/vomiting, decreased appetite, pain/relief after Periumbilical ecchymosis (Cullen sign) and flank
eating, pain/relief after bowel movement (BM), last ecchymosis (Turner sign) are suggestive of retro-
normal BM, bloody BM, menstrual history/symp- peritoneal hemorrhage and, more specifically, pan-
toms, dysuria, and hematuria. At times, the history creatic hemorrhage. Patients with acute appendicitis
can be limited by the patient’s clinical condition or can exhibit Rovsing’s sign (rebound tenderness in the
inability to adequately describe the pain due to poor right lower quadrant on palpation of the left lower
localization and potential radiation of visceral pain. quadrant) and psoas sign (increased abdominal pain
with resisted hip flexion, which suggests inflamma-
EXAMINATION tion of the psoas muscle).
The goals of the physical exam are to determine the Unfortunately, diagnosing the etiology of abdom-
overall condition of the patient, assess the severity of inal pain can be frustrating due to nonspecific signs
the intra-abdominal disease process, and identify the and symptoms, especially in the elderly. Sometimes
likely cause of the pain. As always, vital signs help observation of disease progression, repeat physical
differentiate a “sick” versus “not sick” patient. The examination, advanced imaging studies, and/or sur-
abdominal exam can provide immediate feedback to gical exploration are needed to determine the exact
the emergency physician regarding the severity and etiology of abdominal pain. Nonetheless, emergency
underlying etiology of abdominal pain. Palpation physicians are regularly called upon to identify those
yields the most useful information, particularly when patients with acute abdominal pain requiring surgi-
it is performed by experienced physicians. Systemati- cal intervention. The remainder of this article will
cally work your way around the abdomen, feeling for review specific causes of abdominal pain that require
masses and localizing the pain. Sometimes, in order surgical intervention.

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ACUTE SURGICAL ABDOMEN

TABLE 1. Selected Causes of Acute Surgical Abdomen


Location/Quality Primary Laboratory
Etiology of Pain Symptoms Tests Imaging Treatment

Mesenteric General, out of Postprandial Lactate, CBC CT angiography Antibiotics


Ischemia proportion to exam abdominal
findings pain

Appendicitis Periumbilical migrat- Anorexia, CBC CT Antibiotics


ing to McBurney’s nausea,
point vomiting

Cholecystitis RUQ Pain, jaundice, Bilirubin, RUQ Antibiotics


fever lipase ultrasonography
measurement,
liver function
tests

Diverticulitis LLQ Pain CBC CT Antibiotics

Small Bowel Generalized Nausea, Basic metabolic Acute Nasogastric


Obstruction vomiting, profile abdominal tube, IV fluids
distention series, CT with
oral contrast

Abdominal Severe abdominal/ Pain CBC, CT angiography b-Blocker/


Aortic back pain coagulation CCB*
Aneurysm studies

CBC = complete blood count; CT = computed tomography; RUQ = right upper quadrant; LLQ = left lower quadrant; IV =
intravenous; CCB = calcium channel blocker.
* For systolic blood pressure of 120 to 130 mm Hg.

CAUSES OF ACUTE SURGICAL ABDOMEN (AAS: upright chest radiograph, upright abdominal
radiograph, and a flat abdominal radiograph) often
Perforated Viscus shows free air and is diagnostic of perforated vis-
Perforated viscus is a surgical emergency that can cus. Diseases that can progress to organ perforation
lead to serious morbidity and, commonly, mortal- include mesenteric ischemia, diverticulitis, appendi-
ity. To provide the best possible outcome, the emer- citis, bowel obstruction, cholecystitis, incarcerated/
gency physician must maintain a high level of clinical strangulated hernia, and peptic ulcer disease. Table
suspicion for perforation in the patient with acute 1 highlights characteristic and important features of
abdominal pain. Concurrent resuscitation and diag- some of these disease processes.
nosis of the patient, along with mobilization of the
appropriate resources (surgical consultation, operat- Appendicitis
ing room team) are first-line goals. The abdominal Appendicitis occurs following obstruction of the lu-
exam is often telling in these patients, but imaging men of the appendix, typically secondary to a fecalith.
must often be used to augment the clinical exam The obstruction leads to trapping of mucosal and
and provide important information to the surgeon, bacterial fluids and a subsequent increase in appendi-
who must plan the procedure. An upright chest ceal volume. Increased intraluminal pressure causes
radiograph by itself or an acute abdominal series distention, resulting in visceral pain that is typically

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ACUTE SURGICAL ABDOMEN

diffuse or periumbilical. Subsequent inflammation


that develops around the appendix leads to perito- TABLE 2. Alvarado Scale
neal irritation, which causes the pain to localize, typi-
cally near McBurney’s point. Over time, continued
pressure leads to appendiceal wall ischemia and the Exam Finding Point(s)
possibility of rupture. History
Patients often present with anorexia and ab- Migration of pain 1
dominal pain followed by vomiting. Unfortunately,
Anorexia 1
atypical presentations are common as well. The most
sensitive signs for appendicitis are right lower quad- Nausea/vomiting 1
rant pain (classically described as periumbilical pain Physical Exam
migrating to the right lower quadrant), abdominal wall RLQ tenderness 2
rigidity, pain before vomiting, and a positive psoas
Rebound 1
sign. Anatomical variations of the appendix play a
role in atypical presentations and location of pain. Increased temperature 1
One study showed that 32% of pediatric patients do Laboratory Results
not have the classically described right lower quad- Leukocytosis 2
rant pain, making the diagnosis difficult and pos-
Left shift 1
sibly delaying definitive treatment.3 Therefore, the
high clinical suspicion for appendicitis is warranted
RLQ = right lower quadrant
in the patient with acute abdomen. A recent study Adapted from Alvarado.6
by Frei et al demonstrated that delayed diagnosis
of appendicitis declined following widespread use
of CT scanning, decreasing from 7.8% in 1998 to higher should receive a surgical consultation without
3.0% in 2004.4 imaging (score sensitivity, 77%; specificity, 100%).7
Imaging, such as CT or ultrasonography, is com- Treatment for appendicitis is appendectomy,
monly employed to facilitate diagnosis. On ultra- because the risks of rupture are well-known. It is
sound, a noncompressible appendix greater than 6 important to start antibiotics in the ED. Other dis-
mm is considered diagnostic of appendicitis, and orders can mimic appendicitis, so it is important to
thickened appendiceal wall and periappendiceal fluid have a broad differential diagnosis and to consider
are highly suggestive.5 Ultrasound can be particu- other possibilities. In some hospitals, it is not uncom-
larly useful in pregnant patients, but CT is often mon for an appendix to be found normal during sur-
preferred in the ED because it is accessible and it gery for presumed appendicitis; thus, surgeons may
can be used to evaluate other etiologies. Prudent CT request CT or another imaging modality to confirm
scanning minimizes unnecessary exposure to ioniz- the diagnosis. This request depends on the surgeon’s
ing radiation. On CT, an appendix dilated more than experiences and habits, patient age and history, and
6 mm, a thickened appendiceal wall, a fecalith, and/ other findings obtained during evaluation.
or phlegmon, all suggest acute appendicitis in the
proper clinical setting.5 When it is not readily ap- Mesenteric Ischemia
parent whether CT should be ordered, the Alvarado Mesenteric ischemia can have one of four causes:
scale can be used as an aid in decision making.6 The arterial emboli, arterial thrombus, vasospasm, and
Alvarado scale assigns points for certain signs, symp- venous thrombus. Mesenteric ischemia is classically
toms, and laboratory values, as noted in Table 2.6 described as causing abdominal pain out of propor-
McKay and Shepherd concluded that to confirm a tion to exam findings in affected patients. Patients
diagnosis of appendicitis, ED patients with Alvarado often report severe generalized or periumbilical pain.
scores of 3 or lower probably do not need CT (score They may also have bloody bowel movements, nau-
sensitivity, 96.2%; specificity, 67%), while those with sea, vomiting, food aversion, weight loss, abdominal
scores of 4 to 6 should undergo CT (score sensitivity, distention, and peritoneal symptoms. Postprandial
35.6%; specificity, 94%), and those with scores of 7 or abdominal pain is the most prevalent preceding

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ACUTE SURGICAL ABDOMEN

symptom8 and is sometimes described as “intestinal fects of these processes (eg, bowel wall thickening,
angina.” inflammation, perforation), as well as for evaluating
Mesenteric ischemia can be either acute or other causes of abdominal pain.
chronic, with the acute type presenting emergently. In a patient with peritoneal signs in whom mes-
The natural history of mesenteric ischemia produces enteric ischemia is suspected, early surgical consul-
a spectrum of clinical findings and abnormalities on tation is crucial, and the consult is often initiated
workup, with individual presentation depending on before the diagnosis is established definitively. These
the extent of disease progression. The exam may yield patients often require an emergent laparotomy for
significant findings or may reveal very little. The lat- resection of infarcted bowel in order to survive. For
ter situation, unfortunately, can be falsely reassuring. patients without peritoneal signs, thrombolysis or
Thus, when mesenteric ischemia is suspected but the vascular bypass may be considered by the consul-
exam or initial workup provide little support for the tant surgeon. Anticoagulation therapy is indicated
diagnosis, observation and serial examination and for acute mesenteric venous thrombosis, which may
testing (usually in concert with a surgical consult) not be diagnosed until the patient is in the operat-
may be of benefit. Mesenteric ischemia should be ing room. Early, empiric antibiotic treatment is also
part of the differential diagnosis in any patient with generally recommended.10
abdominal pain and a history of atrial fibrillation,
hypercoagulable state, heart valve disease, recent co- Biliary Tract Disease
caine use, or vascular disease, even if the exam and Biliary tract disease is frequently diagnosed in the
workup are relatively unremarkable. ED, with cholecystitis being much more common
Diagnostic workup of patients with mesenteric than cholangitis. Right upper quadrant pain and
ischemia can be frustrating. Some patients have vomiting, especially in the presence of fever, suggests
leukocytosis and elevated amylase levels. Acidosis, if the potential for surgical consulatation for biliary
present, generally indicates that the disease has pro- tract disease. On physical exam, the presence of Mur-
gressed to a late stage and the patient already has full- phy’s sign suggests cholecystitis. Workup for biliary
thickness bowel injury. Imaging is often used to aid tract disease includes electrolytes, renal function, a
in diagnosis. Although an- complete blood count, and measurements of serum
>>FAST TRACK<< giography is the gold stan- bilirubin, alkaline phosphatase, and lipase levels. In
Mesenteric ischemia dard exam, it is not available addition, imaging should be ordered, especially in
in many EDs. CT angiog- elderly patients. Ultrasonography of the right up-
should be part of the
raphy can be a useful tool per quadrant is the test of choice and is commonly
differential diagnosis
in the diagnosis of mesen- utilized in the ED.
in any patient with teric ischemia, with recent Gallstones are common in American adults, and
abdominal pain studies showing a sensitiv- the prevalence increases with age. Gallstones can
and a history of ity of 96% and specificity lodge anywhere in the biliary tract, from the gall-
atrial fibrillation, of 94%.9 Common findings bladder neck to the common bile duct. Prolonged
hypercoagulable state, indicative of mesenteric obstruction leads to inflammation and promotes sub-
heart valve disease, ischemia include pneuma- sequent bacterial invasion. In many cases, patients
recent cocaine use, or tosis intestinalis, venous presenting with an acute surgical abdomen caused
vascular disease, even if gas, superior mesenteric by biliary tract disease have had a delay in diagnosis.
the exam and workup are artery (SMA) occlusion, ce- This occurs more often in elderly patients, as the
relatively unremarkable. liac and inferior mesenteric early presentation of disease in this age-group can
arterial occlusion with distal be subtle, and thus, the diagnosis is easily missed. If
SMA disease, and/or arterial embolism. Alternatively, biliary tract disease is diagnosed as the cause of a
bowel wall thickening combined with a finding of a patient’s acute abdomen, early antibiotics with fluid
focal lack of bowel wall enhancement, solid organ resuscitation and surgical consultation are critical for
infarction, or venous thrombosis also suggests the a favorable outcome. Patients who do not respond
diagnosis.9 CT angiography is useful for evaluating to initial therapy may require emergent biliary de-
arterial and venous occlusions and the secondary ef- compression.

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It is particularly important to recognize ascending ischemia and necrosis. This occurs most commonly
cholangitis, as this form of biliary tract disease can in a closed loop obstruction.
become fulminant if it is not treated appropriately. Patients tend to present with the classic triad of
Charcot’s triad of right upper quadrant pain, fever, abdominal pain, vomiting, and obstipation. However,
and jaundice is classically described in cholangitis because there is a continuum from partial to com-
and can progress to Reynolds’ pentad with the ad- plete obstruction, the severity of signs and symptoms
dition of mental status changes and shock, which may vary. For example, early in the course of an SBO,
represents the extreme of the spectrum. Ascending patients may still have some bowel movements and
cholangitis typically results from obstruction of the gas in the rectum. Laboratory testing in SBO has
common bile duct with subsequent migration of bac- limited diagnostic value in the ED setting, but it
teria into the lymphatics and hepatic veins. Thus, it can be useful in identifying dehydration and elec-
is important to maintain a high level of suspicion trolyte abnormalities that should be addressed prior
for this disease. to surgery. Imaging is needed to assess whether the
obstruction is partial or complete. An AAS is cost-
Diverticulitis effective and provides useful diagnostic clues. If an
Diverticulitis occurs when bacteria proliferate within obstruction is present, the AAS will show dilated
a diverticulum, a process that can lead to perfora- loops of small bowel, air-fluid levels, and a paucity
tion and acute surgical abdomen. Diverticulitis is of air in the colon and rectum. Abdominal radio-
more common in the elderly and often causes pain graphs were found to have a sensitivity of 82% and
in the left lower quadrant but can occur through- specificity of 83% in diagnosing SBO, but accuracy
out the colon. As the infection progresses, the wall was dependent on the radiologist’s level of experi-
tension of the diverticulum can increase, leading to ence.13 CT is often employed, since it can localize a
spontaneous rupture. The rupture can be relatively transition point and identify other intra-abdominal
contained, forming an abscess, or it can be a large processes. Additionally, CT can help differentiate be-
perforation leading to acute peritonitis. Interestingly, tween SBO, closed loop obstruction, ileus, or colonic
Issa et al found that recurrent bouts of diverticulitis obstruction.
do not correlate with a more complicated clinical Therapy in the ED
course.11 They found that patients without a previous generally includes fluid
>>FAST TRACK<<
Therapy for small bowel ob-
episode of diverticulitis had a higher rate of perfora- resuscitation, placement
tion, while patients with a history of diverticulitis had of a nasogastric tube for
struction in the ED generally
a higher rate of phlegmon or abscess formation. CT decompression, analgesia, includes fluid resuscitation,
of the abdomen and pelvis with IV contrast is useful antiemetics, and a surgical placement of a nasogastric
for assessing the extent of diverticulitis and evaluat- consult. With a complete tube for decompression, an-
ing for abscess and/or perforation. Serial abdominal SBO, the risk of ischemia algesia, antiemetics, and a
exams will ensure early recognition of disease pro- and perforation is signifi- surgical consult.
gression and the need for surgical intervention, if cant. Thus, emergent sur-
applicable. Antibiotics are essential in the treatment gical decompression is required. Patients with partial
of diverticulitis, as well. SBO are often admitted and observed for progres-
sion versus resolution of signs and symptoms over
Small Bowel Obstruction the next 48 hours. Any evidence of developing peri-
Small bowel obstruction (SBO) is a common surgi- tonitis should prompt urgent surgical intervention.
cal disorder of the small intestine.12 Adhesions from
previous surgeries account for the majority of SBO Abdominal Aortic Aneurysm
cases, while other etiologies, including hernias and Patients with a ruptured abdominal aortic aneurysm
Crohn’s disease, are less frequently seen.12 With SBO, (AAA) often die prior to arrival in the ED, or after
swallowed food, liquid, and air, as well as secretions arrival but before reaching the OR.14 Often, patients
from the GI tract, progressively accumulate proxi- with an AAA are unaware of it prior to the onset of
mal to the obstruction. Areas with high intraluminal symptoms; thus, a high index of suspicion on the part
pressures can impair blood flow, causing intestinal of the emergency physician is paramount. Patients

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ACUTE SURGICAL ABDOMEN

with AAA frequently complain of sudden severe ab- pertinent information quickly in order to stabilize and
dominal and/or back pain and may also note a syn- refer the patient is crucial. As always, proper manage-
copal episode with the onset of pain, which likely ment from the outset of the patient’s contact with the
represents the initial rupture. The patient presenting hospital provides the best possible outcome. ■
to the ED with a symptomatic AAA likely has a con-
tained rupture and may initially be hemodynamically REFERENCES
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