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Disease and Immunity Year 12 Biology pr i ACROSS 8 When the Immune system recognises a non-self antigen It prepares a specific reaction tot In the form of a pratein {hat binds to antigens on the pathogens calls. Ths incapactates them and attracts phogocytes to dispose of them. There are five main categories of these proteins and several cellular Interact ons invalved with their production 10 Caused by bacterial toxins on undercooked or contaminated food 12 Transmission via €o airoorne partides. 15 Produced by many bacteria including Clostridium tetani (Tetanus) and Treponema palidum (Syphilis) - which ‘cause the person to develop neurological symptoms. 16 white cells Ingest and digest invading microbes as 2 non Specie Immune response. 18 The abilty to build a long term memory by specialised functions of the T Lymphocyte Cells and their ability to store information about previously encountered pathogens 19 Structures (usually proteins) found on the surface of every cel. Invading organisms also carry them and Antibodies are formed to be specific for them, 20 Site of pathogen entry Respiratory tract, Gastrointestinal ‘tract, Urogenital tract breaks in the skin. 21.An insect or animal that carties a pathogen fram one hast to another aminated water, food, surface or DOWN, 1 Transmission via kissing, sexual Intercourse, or sharing of bodily fluids 2 Physical and chemical barriers to prevent pathogens from invading the body and first line cellular defence ‘mechanisms, 3 Exposing individuals to spectic pathogenic microbes wich artificially Increases their immunity towards I. 4 Play a key role in maintaining life on earth including fixing (gasses and breaking down organic matte” into simpler Substances. Also produce useful substances. 5 Key functions of tne Immune system, 6 present in large numbers in and on 3 host with a symbiotic Felationship. 7. Amicroorganism that has the potential to cause disease. 9 Chemical compounds produced by sol fungi and bacteria, that are used to treat bacterial infections by Killing the, bacteria, or preventing cells from multiplying so the host's defence mechanisms can fight the infection 10s the escape of a pathogen from one host and transported to another. 11 Sebum, Gastrointestinal pH, Lysozymes (in saliva and tears), 13 Meerosrganisms that are na longer killed or inhibited by an antibictie that they were previously sensitive to Because of misuse of antibiotics. MRSA is an example of this, 14 Invasion and multiplication of pathogenic microbes in an individual or population. 17 When an infection causes damage to the individuals vital functions or syste.

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