Keterangan

Drug half-life,T1/2 120 Minutes Volume of dist, Vd 0.12

Elimination rate, r 0.005760 Prop.in plasma, p 0.333333
Absorption rate, a 0.036 Body weight 200
Dosage amount, d 200 mg Plasma volume 3.628776
Dose frequency, f 6.0 hours
Dissolution time, 30.0 Minutes
Total doses, N 2

t (minutes) D (t) GI (t) B(t) PC(t) (mg/l)

0 6.666667 6.7 0 0
1 6.666667 13.13 0.241 0.02215623
2 6.666667 19.32 0.712 0.065433225225399
3 6.666667 25.29 1.404 0.12894439749393
4 6.666667 31.05 2.306 0.211835802890436
5 6.666667 36.60 3.411 0.313284962385513
6 6.666667 41.95 4.708 0.432499724935991
7 6.666667 47.10 6.191 0.568717171537794
8 6.666667 52.07 7.851 0.721202558756722
9 6.666667 56.86 9.681 0.889248300315844

Effective contract rate, 0.9

Duration of infectivity, 10
Total population, N 5000
Birth and dreath rate, 0.0005

t s(t) I (t) r (t)

0 4995 5 0 1000
1 4991 9 1
2 4982 16 60001
3 4968 29 3
4 4942 52 50006
5 4896 93 11
6 4813 166 20
4000
7 4669 294 37
8 4422 511 66
3000
9 4016 867 118
10 3389 1407 204
2000
11 2531 2124 345
12 1563 2879 557
1000
13 753 3402 845
14 292 3523 1185
0
15 107 3355 15381 2 3 4 5 6 7 8 9 10111213141516171819202122232
 1000

0
1 2 3 4 5 6 7 8 9 10111213141516171819202122232
16 42 3084 1873
17 19 2800 2182
18 9 2529 2462
19 5 2280 2715
20 3 2054 2943
21 2 1850 3148
22 1 1666 3333
23 1 1500 3500
24 1 1350 3650
25 0 1215 3785
26 0 1094 3906
27 0 984 4015
28 0 886 4114
29 0 797 4202
30 0 718 4282
31 0 646 4354
32 0 581 4419
33 0 523 4477
34 0 471 4529
35 0 424 4576
36 0 381 4618
37 0 343 4657
38 0 309 4691
39 0 278 4722
40 0 250 4750
 Keterangan
kg

pounds
liters

s(t)
I (t)
r (t)

1121314151617181920212223242526272829303132333435363738394041
1121314151617181920212223242526272829303132333435363738394041
1.73 0.27 1.11 1.19 2.91 4.81 λ
1.98 3.44 1.04 0.81 1.14 4.00 bins
0.04 2.17 1.12 0.05 1.93 0.58 bin width
0.26 0.44 4.27 2.31 0.41 3.38 Customer Number
7.10 0.12 0.26 1.86 1.07 2.27 1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
 0.555
10
0.721
Time Between Arrivals bins count rel frequency bin width*x
1.00510142467619 0.36046666667 30 0.375 0.2498311497
0.866526215806609 1.0814 29 0.3625 0.09745851216
0.523973980630841 1.80233333333 28 0.35 0.03801832399
0.841311242306625 2.52326666667 27 0.3375 0.01483085394
2.6962703979154 3.2442 26 0.325 0.00578547936
0.033830278324254 3.96513333333 25 0.3125 0.00225690115
0.567248197957166 4.68606666667 24 0.3 0.00088041155
6.14755479934544 5.407 23 0.2875 0.00034344636
5.01499408943731 6.12793333333 22 0.275 0.00013397757
0.442921607225967 6.84886666667 21 0.2625 5.22643196E-05
0.811618377587122 7.5698 20 0.25 2.03881815E-05
0.118982437718405 8.29073333333 19 0.2375 7.95337906E-06
1.7159861891241 9.01166666667 18 0.225 3.10259345E-06
0.581649518590261 9.7326 17 0.2125 1.21031402E-06
2.66948160035667 10.4535333333 16 0.2 4.72140497E-07
2.78604061289233 11.1744666667 15 0.1875 1.84180837E-07
0.841898892393154 11.8954 14 0.175 7.18484881E-08
4.14556252299304 12.6163333333 13 0.1625 2.80279171E-08
0.090318395909199 13.3372666667 12 0.15 1.0933621E-08
0.371439878226379 14.0582 11 0.1375 4.26517844E-09
2.41243220988638 14.7791333333 10 0.125 1.66383554E-09
0.485020613690581 15.5000666667 9 0.1125 6.49058118E-10
1.30574974657486 16.221 8 0.1 2.53195963E-10
0.166396156780561 16.9419333333 7 0.0875 9.87711174E-11
0.004658245871936 17.6628666667 6 0.075 3.8530368E-11
0.702219423659212 18.3838 5 0.0625 1.5030601E-11
0.664239624850045 19.1047333333 4 0.05 5.86340021E-12
2.21021277248997 19.8256666667 3 0.0375 2.28729789E-12
0.75273757259184 20.5466 2 0.025 8.92269235E-13
0.315920350884615 21.2675333333 1 0.0125 3.48072017E-13
Mean Arrival Rate 3
Mean Service Rate 4

Customer Number Time Between Arrivals Arrivals Time Start Time

1 0.132940757606353 0.1329407576064 0.132940757606
2 0.004115750339288 0.1370565079456 0.166988211662
3 0.557872255373203 0.6949287633188 0.694928763319
4 0.185799511071932 0.8807282743908 1.221371111455
5 0.45912480619469 1.3398530805855 1.400068105313
6 0.672231394396884 2.0120844749824 2.14029539684
7 0.887178918916537 2.8992633938989 2.899263393899
8 0.099246326079621 2.9985097199785 3.096569724887
9 0.054594577020794 3.0531042969993 3.401587526205
 bj

Service Time Completion Time Wait Time Comulative Wait

Average
Time Wait Time
Trial Number
0.03404745406 0.166988211662109 0 0 0
0.35515095787 0.522139169531576 0.02993170371647 0.02993170372 0.014966 1
0.52644234814 1.22137111145489 0 0 0 2
0.17869699386 1.40006810531323 0.34064283706412 0.34064283706 0.085161 3
0.74022729153 2.14029539684032 0.06021502472776 0.06021502473 0.012043 4
0.07007092068 2.21036631751725 0.12821092185797 0.12821092186 0.021368 5
0.19730633099 3.09656972488692 0 0 0 6
0.30501780132 3.40158752620511 0.09806000490841 0.09806000491 0.012258 7
0.13445195182 3.53603947802319 0.34848322920581 0.34848322921 0.03872 8
 Avg. Wait Time Over all average
0.038720358800646 0.0387203588006
0.050606466669166
0
0.026733392924278
0.189657521709445
0.039120398635415
0
0.09244943465915
0