Alzheimer/Dementia Disease

By Adam
 WHAT IS ALZHEIMERS
• Alzheimer's disease is the most common cause of dementia. The word dementia
describes a set of symptoms that can include memory loss and difficulties with thinking,
problem-solving or language. These symptoms occur when the brain is damaged by
certain diseases, including Alzheimer's disease.
• Alzheimer's disease, named after the doctor who first described it (Alois Alzheimer), is a
physical disease that affects the brain. There are more than 520,000 people in the UK
with Alzheimer's disease. During the course of the disease, proteins build up in the brain
to form structures called 'plaques' and 'tangles'. This leads to the loss of connections
between nerve cells, and eventually to the death of nerve cells and loss of brain tissue.
People with Alzheimer's also have a shortage of some important chemicals in their brain.
These chemical messengers help to transmit signals around the brain. When there is a
shortage of them, the signals are not transmitted as effectively. As discussed below,
current treatments for Alzheimer's disease can help boost the levels of chemical
messengers in the brain, which can help with some of the symptoms.
• Alzheimer's is a progressive disease. This means that gradually, over time, more parts of
the brain are damaged. As this happens, more symptoms develop. They also become
more severe.
 WHAT IS ALZHEIMERS
Alzheimer's disease leads to nerve cell death and tissue loss throughout the brain. Over time, the
brain shrinks dramatically, affecting nearly all its functions.
 WHAT IS ALZHEIMERS
• “It has been known for years that Alzheimer’s starts in a brain region known as the entorhinal cortex,” said
co-senior author Scott A. Small, MD, Boris and Rose Katz Professor of Neurology, professor of radiology, and
director of the Alzheimer’s Disease Research Center. “But this study is the first to show in living patients that
it begins specifically in the lateral entorhinal cortex, or LEC. The LEC is considered to be a gateway to the
hippocampus, which plays a key role in the consolidation of long-term memory, among other functions. If
the LEC is affected, other aspects of the hippocampus will also be affected.”
• The study also shows that, over time, Alzheimer’s spreads from the LEC directly to other areas of the
cerebral cortex, in particular, the parietal cortex, a brain region involved in various functions, including
spatial orientation and navigation. The researchers suspect that Alzheimer’s spreads “functionally,” that is,
by compromising the function of neurons in the LEC, which then compromises the integrity of neurons in
adjoining areas.
• A third major finding of the study is that LEC dysfunction occurs when changes in tau and amyloid precursor
protein (APP) co-exist. “The LEC is especially vulnerable to Alzheimer’s because it normally accumulates tau,
which sensitizes the LEC to the accumulation of APP. Together, these two proteins damage neurons in the
LEC, setting the stage for Alzheimer’s,” said co-senior author Karen E. Duff, PhD, professor of pathology and
cell biology (in psychiatry and in the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain)
at CUMC and at the New York State Psychiatric Institute.
• http://newsroom.cumc.columbia.edu/blog/2013/12/22/how-alzheimers-spreads/
 WHAT IS ALZHEIMERS

• The most important of these is that a protein known as α-synuclein (α-syn) accumulates in the
brain, in both Parkinson’s and SDS/MSA. This accumulation is very similar to what happens in CJD,
where the prion protein (PrP) accumulates, and also in Alzheimer’s disease and other dementias,
where two types of proteins, known as amyloid beta (Aβ-amyloid) and tau, build up in the brain.
 WHAT IS ALZHEIMERS
• Mild Alzheimer's disease (early-stage)
• The onset of Alzheimer's disease cannot yet be stopped or reversed,
In the early stages of Alzheimer's, a person may function independently. He or she may still drive,
work and be part of social activities. Despite this, the person may feel as if he or she is having
memory lapses, such as forgetting familiar words or the location of everyday objects. Friends,
family or neighbors begin to notice difficulties. During a detailed medical interview, doctors may be
able to detect problems in memory or concentration. Common difficulties include:
• Problems coming up with the right word or name
• Trouble remembering names when introduced to new people
• Having greater difficulty performing tasks in social or work settings
• Forgetting material that one has just read
• Losing or misplacing a valuable object
• Increasing trouble with planning or organizing
 WHAT IS ALZHEIMERS
• Moderate Alzheimer's disease (middle-stage)
• During the moderate stage of Alzheimer's, individuals may have greater difficulty performing tasks such as paying bills, but they may still
remember significant details about their life. Moderate Alzheimer's is typically the longest stage and can last for many years. As the disease
progresses, the person with Alzheimer's will require a greater level of care. You may notice the person with Alzheimer's confusing words,
getting frustrated or angry, or acting in unexpected ways, such as refusing to bathe. Damage to nerve cells in the brain can make it difficult
to express thoughts and perform routine tasks. At this point, symptoms will be noticeable to others and may include:
• Forgetfulness of events or about one's own personal history
• Feeling moody or withdrawn, especially in socially or mentally challenging situations
• Being unable to recall their own address or telephone number or the high school or college from which they graduated
• Confusion about where they are or what day it is
• The need for help choosing proper clothing for the season or the occasion
• Trouble controlling bladder and bowels in some individuals
• Changes in sleep patterns, such as sleeping during the day and becoming restless at night
• An increased risk of wandering and becoming lost
• Personality and behavioral changes, including suspiciousness and delusions or compulsive, repetitive behavior like hand-wringing or
tissue shredding
 WHAT IS ALZHEIMERS
• Severe Alzheimer's disease (late-stage)
• In the final stage of this disease, individuals lose the ability to respond to their environment, to
carry on a conversation and, eventually, to control movement. They may still say words or
phrases, but communicating pain becomes difficult. As memory and cognitive skills continue to
worsen, personality changes may take place and individuals need extensive help with daily
activities.
At this stage, individuals may:
• Require full-time, around-the-clock assistance with daily personal care
• Lose awareness of recent experiences as well as of their surroundings
• Require high levels of assistance with daily activities and personal care
• Experience changes in physical abilities, including the ability to walk, sit and, eventually,
swallow
• Have increasing difficulty communicating
• Become vulnerable to infections, especially pneumonia
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What is the burden of Alzheimer’s disease in the United States?
• Alzheimer’s disease is
• One of the top 10 leading causes of death in the United States.2
• The 6th leading cause of death among US adults.
• The 5th leading cause of death among adults aged 65–85 years.3
• In 2013, an estimated 5 million Americans aged 65 years or older had Alzheimer’s disease.1 This
number may triple to as high as 13.8 million people by 2050.1
CDC.gov
 WHAT IS ALZHEIMERS
• Nelsonian Homeopathy
• Hormetics: Metals.
• Combinations: Cephalo-M.
• Liquitrophics: G Liquitrophic; Lipid Liquitrophic; Seroto Liquitrophic.
• Supplements: Phosphatydl Choline.
• Homeopathy
• Argentum nitricum, Baryta carbonica, Lycopodium, Phosphorus, Alumina
• Herbal Aid
• Ginkgo (Ginkgo biloba); Blessed Thistle, Cayenne pepper, Ginseng, Quinoa,
Flax, Spirulina, Alfalfa, Speedwell, Garlic, Chinese Club Moss (Huperzia
serrata).
 WHAT IS ALZHEIMERS
• Vitamins-Minerals
• Vitamin E, C, B-group (esp. Folic acid), Zinc, Selenium
• Other Sources
• Lethicin, DMAE, Fishfood, Nuts, L-Carnitine, Acetyl-L-Carnitine, (also
check Memory / Concentration), Q10, Phosphatidylserine, all of the
essential Amino-acids especially Tyrosine.
• Fish, nuts, apples, kelp, Spirulina, green foods (wheat grass, barley,
etc.) Ginkgo Biloba, garlic and regular walks.
• Avoid: Sugars, meat, alcohol, nicotine
 WHAT IS ALZHEIMERS
• Notes
• A recent study found that 4-5 daily dosages of vitamin E in combination with a drug for Parkinson's (check
with your doctor) helped to slow down the disease by 25%. A study from England suggests that Folic acid
may be used in the prevention of Alzheimer's.
• Still another study suggests that even mental activity may help prevent Alzheimer's. It was long known that
mental activity could increase the number of neurons in the brain.
• Ginkgo, Vitamin E, Blessed Thistle and Cayenne pepper increase the blood and oxygen supply in the brain
and rest of the body (In tests Ginkgo has shown promising results).
• Since an excess amount of aluminum and bromine was found in the hippocampus and cerebral cortex, it
would be very wise to avoid any further contact with these chemicals.
• Note: Some studies are now supporting the claim that Ginkgo Biloba has a positive effect on Alzheimer
clients.
• Newer studies have shown that Acetyl-L-Carnitine protects brain functions and can even restore more
brainpower to sufferers of Alzheimer's and in the elderly. See Alzheimer's in Sources.
• It is important to take Acetyl-L-Carnitine because L-Carnitine does not pass the blood-brain barrier.
 WHAT IS ALZHEIMERS
• Acetylcholine and Galantamine:
• A new treatment for Alzheimer's promises the long expected breakthrough. A lack of
Acetylcholine has long been implicated in Alzheimer's. Galantamine, an extract of the Daffodil
bulb and discovered by Janssen, inhibits the enzyme responsible for the destruction of
Acetylcholine. Steven G. Potkin, M. D. of the UCI Neuropsychiatric Center is testing Galantamine
for its Efficacy, Tolerability, and Safety.
• Rivastigmine
• Another new drug, Rivastigmine (ENA-713), was presented at an International Conference on
Alzheimer's in Amsterdam. The observed improvements were the largest recorded for an anti-
dementia medication.
• Bleomycin hydrolase
• According to research done at the University of Pittsburgh a naturally occurring enzyme,
Bleomycin hydrolase, increases the risk of Alzheimer's by a factor of four. This could have an affect
on about 6 % of the population. Published in "Nature Genetics (March, 98)".
• .
 WHAT IS ALZHEIMERS
• Homocystein A
• In several studies, the amino acid Homocystein A has also been implicated as an increased risk of
Alzheimer's.
• Metrifonate
• Testing 1,218 clients with mild to moderate Alzheimer's, researchers at the McGill University concluded that
the drug Metrifonate significantly improved Alzheimer's.
• Anabaseine
• The journal "Naturwissenschaften" reports that Anabaseine, a chemical derived from ants, has shown a
degree of improvement in Alzheimer clients.
• Donepezil
• Another drug showing promise is the drug Aricept (donepezil). This research done at the Baylor College of
Medicine was published in "Neurology (Febr., 98)".
• Anti-inflammatory drugs
• Anti-inflammatory drugs and protease inhibitors, which block the production of amyloid beta-peptide, have
shown promise in the treatment of Alzheimer's
 WHAT IS ALZHEIMERS
• Gotu Kola
• In related news articles, research has found that Gotu Kola has a positive effect on
Alzheimer's. Other natural products helpful in Alzheimer's include anti-oxidants, like
vitamin E, and estrogen, found in soy beans and licorice root.
• Anti-oxidants and Vitamin E
• US studies have shown that cell death caused by an atoxic protein found in Alzheimer
clients can be prevented by daily supplements of Vitamin E and other anti-oxidants.
• Estrogen / Isoflavones (Soy and Licorice)
• There are indications that Estrogen may lower the risk of Alzheimers. Estrogen-like
substances are also found in soy beans and licorice root.
• Note: When taking licorice root, diet should include potassium.Dr. Tom Thomas of the
University of South Florida in Tampa says the explanation for estrogen's action may be
found in its prevention of vascular damage caused by amyloid beta-peptides that cause
inflammations.
 Summary
• Summary

Physical LEC (Temporal lobe), Hippocampus, Cerebral Cortex, Heart

Brain circulation. Amyloids proteins (kidney brain stem connection
Chrom 4Q)

Infectious/Nosode; Prion, Mycoplasma, Lyme, Rickettsia, Rocky Mt,

Epstein Bar, Cytomegalo, Brucella, Babesia, Bartonela (bartonelosis)

Emotional Separation Conflict (Hammer)