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Definition Etiology
Inability to initiate activity, maintain activity. Psychologic: depression, anxiety, somatization disorder,
Difficulty with concentration, memory, emotional stability. malnutrition/drug addict.
Different from somnolence, dyspnea and muscle Pharmacologic: hypnotic, antiHT (β-blocker), antidepressant,
weakness. antihistamine, opioid, muscle relaxant, drug abuse and
Bisa fisiologis, tapi chronic fatigue (>6mo) ga normal. withdrawal.
(Recent <1mo; Prolonged 1-6mo; Chronic >6mo). Endocrine: hypothyroid, DM, CKD, hepatic failure, apathetic
hyperthyroid, pituitary insufficiency, hypercalcemia, adrenal
Patofisiologi, dapat disebabkan oleh stress: insufficiency.
Psikiatrik (gangguan tidur, masalah kejiwaan) Neoplastic-hematologic: occult malignancy, severe anemia.
Fisikal (oksigenasi jaringan berkurang, hypocortisolism, Infection: TB, hepatitis, HIV, endocarditis, mononucleosis,
dll.) parasitic dz, CMV.
Keduanya Cardiopulmo: CHF, COPD.
Connective tissue: rheumatoid.
Sleep disturbance: sleep apnea, esophageal reflux, allergic
rhinitis, psychologic.
Idiopathic: idiopathic chronic fatigue, chronic fatigue
syndrome, fibromyalgia.
Terapi
treat underlying cause.
Doctor-patient relationship
Antidepressant
Cognitive Behavioral Therapy (lebih baik)
Graded Exercise Therapy
Terapi
-Ferrous sulfate 3.3mg/Hb/hari
untuk anemia iron deficiency.