January 2017
multidisciplinary team developed and implemented the
WINNERS Study (Walking with INtegrated Nursing, Ex-
ercise, Respiratory/Rehab Services), designed to deter-
mine if a formal pre-operative/perioperative interactive
patient education program would positively impact pa-
tient outcomes and improve satisfaction following
thoracic surgery.
Methods: All general thoracic surgery patients undergo
informed consent and are randomized to current stan-
dard of care verbal pre-operative teaching vs pre-opera-
tive/perioperative interactive patient education program.
The multidisciplinary team developed formal patient
educational materials, written and audiovisual, used to
educate and prepare patients for what they should expect
post-operatively with respect to the importance of
secretion management, ambulation, general aspects of
what to expect after surgery and the importance of their
active participation in their post-operative recovery. The
study design is outlined in Figure 1. The endpoints include
length of stay, reintubation rates, pneumonia incidence,
quality of life measurements, physical function measure-
ments (PFT / 6min walk / total steps). Patient satisfaction
is measures with the Quality of Life Instrument, SF-36 at
pre-determined time-points.
Abstracts S1097
Results: Patients are currently actively enrolling into the
study without any recruitment issues or adverse even-
ts.The preliminary analysis demonstrates a favorable
impact on patient outcomes and improved patient
satisfaction.
Conclusion: This study is ongoing.
Keywords: Patient Satisfaction, patient outcomes,
Physical Therapy, Thoracic Surgery Nursing
P2.06-041
TeleNursing: A Thoracic Surgery Nursing
Initiative Aimed at Decreasing Hospital
Readmissions and Increasing Patient
Satisfaction
Topic: LAB, Other
Melissa Culligan,1 Joseph Friedberg,1 Lindsey Black,1
Seantrese Wimbush,1 Colleen Norton,1
Whitney Burrows,1 Shamus Carr,1 James Donahue,1
Marc Zubrow2 1Thoracic Surgery, University of Maryland
Medical Center, Baltimore/MD/United States of America,
2
Medicine, University of Maryland Medical Center,
Baltimore/MD/United States of America
Background: In the USA there is a national initiative in
healthcare to decrease hospital readmissions, decrease
the cost of care while patients are hospitalized and to
increase patient. A recent study evaluating mortality
rates in the lung cancer resection patients reported a 30-
day readmission was associated with a 6-fold increase in
the 90-day mortality of this patient population (14.4% vs
2.5%). This report not only forces thoracic surgery
teams to extend their operative mortality focus and
reporting beyond the traditional 30-day time period but
it also emphasizes the critical value and positive impact
continued post-operative care for the first three months
after discharge can have on patient outcomes. The expert
care delivered by thoracic surgery nurses plays a critical
role in decreasing post-operative complications and
ensuring patients are safely discharged from the hospi-
tal. The valuable impact thoracic surgery nurses have on
preventing hospital readmissions and improving patient
satisfaction is the intended focus of this clinical trial. The
positive impact telehealth interventions have on multiple
different disease processes supports investigation of this
care modality for the thoracic surgery patient popula-
tion. We have designed a clinical trial focused on
implementing a TeleNursing program with the specific
aims of preventing hospital readmissions and improving
patient satisfaction.
S1098
Methods: Our thoracic surgery practice currently has a
“day-after-discharge” follow-up phone call program that
is directed by the thoracic surgery nurses in the practice.
Pertinent clinical details of each patient’s post-operative
course are relayed to the thoracic surgery nurses. The
nurses call patients 2-3 days after discharge and asked
questions related to medications, pain management, sign
or symptoms of infection, activity level and expectations,
sleep, appetite and general understanding of all
discharge instructions. This interaction is documented in
the electronic medical record. This program has been
expanded to compare the efficacy of the phone calls vs
scheduled video-calls between nurses and patients. Pa-
tients are randomized to standard of care day after
discharge phone calls vs the TeleNursing follow-up
video-call; discharge day 2, 1-month, 2-month and 3-
month. All patients complete a patient satisfaction
questionnaire at predetermined time points. The pri-
mary objective is to decrease hospital readmission rates
and the secondary objective is to improve patient
satisfaction.
Results: Although the results of this clinical trial are
pending, interim analysis indicates that patients are
willing to participate in this program and are pleased
with the nurse-patient interaction beyond their hospital
stay.
Conclusion: This clinical investigation is ongoing.
Keywords: Thoracic Nursing, Telemedicine, Thoracic
Surgery, patient outcomes
P2.06-042
Evaluate the Utility of the Computed
Bioconductance Measurement in the
Diagnosis of Lung Cancer
Topic: LAB, Other
Dawei Yang,1 Rex Yung,2 Jing Li,1 Ningfang Wang,1
Xing Gong,1 Jingjing Lu,3 Ye Gu,4 Xiaodong Zhang,5
Tao Ren,4 Hao Wang,4 Wenjie Zhang,6 Jian Zhou,1
Chunxue Bai1 1Department of Pulmonary Medicine,
Zhongshan Hospital Fudan University, Shanghai/China,
2 P2.06-043
Pulmonology, Greater Baltimore Medical Center,
Townson/MD/United States of America, 3Pulmonary
Medicine, Shanghai Dongfang Hospital of Tongji
University, Shanghai/China, 4Shanghai Pulmonary
Hospital, Shanghai/China, 5Nantong Tumor Hospital,
Nantong/China, 6Prolung Biotech Wuxi Co., Wuxi/China
Background: Transcutaneous Computed Bio-
conductance (CB) has been shown to be different be-
tween malignant and benign lung lesions. We have
Journal of Thoracic Oncology Vol. 12 No. 1S
launched a multicenter study to evaluate the utility of
the Computed Bioconductance (CB) measurement
following the CT scan in the diagnosis of lung cancer in
Chinese population.
Methods: In this multicenter study, we analyzed the
result of a non-randomized prospective trail enrolling
123 patients with suspicious lung lesions studied by CT
and CB. The pulmonary nodules or lesions confirmed by
CT scan are greater than 4mm and smaller than 50mm. A
CB test by BSP-E2-1000-A (Prolung Biotech Wuxi Co.,
Wuxi, China) was operated within these patients prior to
an abnormal CT, then the tissue biopsy or surgical
specimen would be conducted within 14 days. The
detailed protocol could be found on ClinicalTrails.gov
identifier NCT02726633.
Results: Among the current 123 enrolling patients, 34
(28%) cases were diagnosed of benign lesion, and 83
(67%) cases were diagnosed of malignant lesion depend
on pathological diagnosis, 6 (5%) cases were eliminated
due to patient refusal of biopsy. In malignant group, 32
(39%) cases were in stage I; 17 (20%) cased were in
stage II and IIIA; 30 (36%) cases were in stage IIIB and
IV. In addition, 10 (12%) cases were with EGFR mutation
and all were adenocarcinoma. In benign group, 2 (6%)
cases were diagnosed of tuberculosis and most other
were inflammation and fibrosis lesion. The sex ratio was
45/78 (female vs. male). In addition, body mass index,
lung functions test, serum tumor biomarker, nodule
position and appearance, medical, treatment and smok-
ing history were collected in the study. Among all cases,
31 had concomitant PET performed and standardized
uptake value were collected.
Conclusion: In this enrolling study, a pre-biopsy
assessment of malignant probability with a CT-detected
lung lesion, the method which combined CT and CB was
evaluated at first time. This non-invasive risk-stratifica-
tion technology could improve the diagnostic efficacy of
lung cancer.
Keywords: CT scan, lung cancer, Multicenter study,
Computed bioconductance
3-Dimensional High Throughput Multi-
Drug Screening Using Patient-Derived
Tumor Cells (PDC) Established from
Surgical Specimens of NSCLC
Topic: LAB, Other
Sumin Shin,1 Yong Sung Shin,2 Hye Joo Choi,2
Jiryeon Jang,2 Jong Ho Cho,1 Hong Kwan Kim,1