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Nicu
Nicu
INTRODUCTION:
The organization of a good quality special care neonatal unit is essential for reducing the neonatal mortality and
improving the quality of life among the survivors. Adequate space, availability of running water round- the-
clock, centralized oxygen and suction facilities, maintenance of thermo neutral environment and ready
availability of plenty of linen and disposables is mandatory to provide optimal level 2 newborn cares. Facilities
for management of common neonatal problems viz. perinatal hypoxia, LBW babies, respiratory distress,
syndrome, septicemia, hyperbilirubinemia and life- threatening congenital malformations should be established.
Effective and optimal management of newborn babies at birth, prevention of hypothermia and bacterial
infections and feeding of all babies with human milk should be ensured before establishing neonatal intensive
care facilities. The philosophy of specialized conservative management of high- risk newborn babies should be
fully exploited to bring down the neonatal mortality rate to less than 30 per 1000 live births before intensive
care facilities are launched.
PHYSICAL FACILITES:
SPACE: The size of the unit is related to the expected population intended to be served. In India, about 15 to 20
percent of newborn babies need special care. If the center is to serve as a referral unit for the infants born
outside the hospital, allowance should be made for additional physical facilities and space. In a maternity unit
having 2,000 deliveries per year, facilities for special care of 8 high- risk infants should be available. Each
infant should be provided with a minimum area of 100 sq.ft. Or 10M2. There should be no compromise on
space and its adequacy is crucial for reduction of nosocomial infection. Space should be allocated within the
nursery complex for promotion of breast feeding, expression of breast milk and its storage. The entry of visitors
to this area should be restricted and it should be kept adequately warm. Facilities for maintaining asepsis and
weighing the babies should be available in the transitional care room (TCR).
LOCATION: The neonatal unit should be located as close as possible to the labor room and obstetric operation
theater, to facilitate prompt transfer of sick and high- risk infants. The presence of an elevator in close proximity
is desirable for transport of out born infants. In tropical countries, the nursery should not be located on the top
floor of the hospital but there should be feasibility for the sunlight to peep into the nursery to enhance
brightness and provide ultraviolet rays to augment asepsis.
FLOOR PLAN: The unit facility should preferably be in a square space so that abundant open unencumbered
space is available. A split unit i.e. on either side of the hospital corridor should be avoided for ease of mobility
and for prevention of infections. The walls should be made of washable glazed tiles and windows should have
two layers of glass panes to ensure some measure of heat and sound insulation. Adequate number of deep wash
basins with elbow of foot operated taps, having constant round- the- clock water supply should be provided.
Built- in wall wooden cabinets with foldable covers are useful for stacking purposes. The doors should be
provided with automatic door closers. In addition to the special care area, minimal care and isolation rooms, x-
ray room, laboratory and a procedure room. The growing nursery is used with advantage for education of
mothers in child craft activities and promoting the practice of breast feeding. The cleaning area is used for
sterilization of equipment and for fumigation of incubators in a specially designed vapor proof chamber.
Isolation room is used to nurse potentially infected inborn or out born babies. The obviously infected inborn
with open sepsis should be admitted in a septic nursery, which must be located away from the SCNU and
manned by different nursing and resident staff.
VENTILATION: Effective air ventilation of nursery is essential to reduce nosocomial infections. The most
satisfactory ventilation is achieved with laminar air flow system which is rather expensive. When centralized air
conditioning is used, minimum of 12 changes of room air per hour are recommended. The air conditioning
ducts must be provided with Millipore filters (0.5 u) to restrict the passage of microbes. A simple method to
achieve satisfactory ventilation consists of provision of exhaust fan in a reverse direction near the ceiling for
input of fresh uncontaminated air and fixation of another exhaust fan in the conventional manner near the floor
for air exit. A constant positive air pressure should be maintained in the nursery so that contaminated air form
the corridors does not gain access into the nursery. The use of chemical air disinfection and ultraviolet lamps
are no more recommended.
LIGHTING: The nursery must be well illuminated and painted white or slightly off white to permit prompt
and early detection of jaundice and cyanosis. It is best achieved by cool white fluorescent tubes to provide at
least 100 foot candle, shadow- free illumination at the infant’s level. The number and exact location of fixtures
can be worked out taking into account size of the nursery, height of the ceiling, and availability or otherwise of
sunlight. Spot illumination for various procedures can be provided by a portable angle- poise lamp having two
15 watt fluorescent bulbs which when held at a distance of about one foot from the infant, produce about 100
foot candle intensity of light. In places where electrical failure is frequent and prolonged, the electrical failure is
frequent and prolonged; the electrical system of the nursery complex must be attached to a generator. Exposure
of preterm babies to strong light has been incriminated as a risk factor for the development of retinopathy of
prematurity. The nursery light should be dimmed at night to simulate day- night pattern to promote hormonal
surge and growth of babies.
ENVIRONMENTAL TEMPERATURE AND HUMIDITY: The temperature of the nursery complex must
be maintained around 26 ± 2C in order to minimize effects of thermal stress on the babies. This is best achieved
by centralized air conditioning having temperature control knobs in the nursery. In places where air
conditioning id not feasible, room temperature can be reasonably well maintained in winter by use of radiant
heaters and hot air blowers. Portable radiant heater, infrared lamp or bakery bulb can be used to provide
additional source of heat to an individual infant.
ACOUSTIC CHARECTERISTECS: the ventilation system, incubators, air compressors, suction pumps and
many other devices used in the nursery produce noise. Sound intensity in the nursery should not exceed 75 db to
protect hearing of nursery personnel and infants. Excessive noise may lead to hearing loss, physiological and
behavioral disturbances such as sleep disturbances, startles and crying episodes, hypoxia, tachycardia and
increased intracranial pressure. The fabrication and redesigning of nursery equipment should take into account
the desirability of minimizing noise by dampening the sound by acoustic or other means. It is desirable to have
effective sound proofing of ceilings, walls, doors and floor when a new nursery is designed. Telephone rings
and equipment alarms should be replaced by blinking light. Instead of air compressors, centralized sources of
compressed air, oxygen and suction should be provided. Decibel meter should be installed to monitor sound
effects of meaningful sounds such as gentle music or recording of parent voice should be harnessed to provide
physiologic stability to the babies.
HANDLING AND SOCIAL CONTACTS: Excessive and rough handling of delicate newborn babies is
associated with several adverse physiological consequences such as excessive cryi9ng sleep disturbances,
tachycardia or bradycardia, hypoxia and rise in blood pressure and intracranial pressure. Handling should be
gentle and kept to the barest minimum without compromising care. Soothing words, gentle stroking and rocking
should be practiced after a painful procedure. Gentle caressing, cuddling and touching by the mother are
desirable to provide comfort and confidence to the baby and aid the process of healing. Infants should be
exposed to gentle and soothing tactile, kinesthetic, vestibular, motor, auditory and visual experiences to provide
opportunities for early learning and improvement in behavior. Parents should be allowed unrestricted entry to
the nursery to provide these useful sensorimotor stimuli. It enhances the process of bonding between the baby
and the family.
COMMUNICATION SYSTEM: The nursery complex should be provided with an intercom system so that
additional person can be called for help in case of emergency without leaving the sick infant. A direct line
external telephone is mandatory so that parents have an easy access to inquire about welfare of their infants and
in turn they can be readily contacted whenever needed. Mobiles phones should not be used near the vicinity of
the nursery because the electromagnetic waves are likely to interfere with the functioning of the electronic
equipment.
ELECTRICAL OUTLETS: There should be adequate number (8-12 electrical points at the height of 4-5
feets) of light and power electrical points attached to a common ground. Each infant must be provided with at
least eight electrical outlets. The electrical equipment used in the nursery must be checked at least once a month
for leakage of current and adequacy of grounding. The voltage supply to the nursery should be stabilized with
the help of a voltage servo- stabilizer. There should be round- the- clock power back up including provision of
UPS system for the sensitive equipments.
PERSONNEL:
The survival of newborn babies depends upon the availability of specially trained nurses. The American
academy of pediatrics that one nurse is needed to offer special or intermediate nursing care to 3 babies or
intensive care to one infant. The National Neonatology Forum of India has recommended that at least one
trained nurse should be allocated to provide coverage to four babies in the special care neonatal unit. The
allowance should be kept for additional 25 percent staff to provide for the exigencies of day off and leave.
Therefore, for an 8- bedded SCNU, eight nurses should be sanctioned to ensure availability of two nurses in
each shift along with one additional sister incharge in the morning shift. There must be equal distribution of
nurse in the three duty shifts during 24 hours. The nurses must be imparted continuing in- service training in the
art of neonatal nursing and preventive maintenance of a variety of electronic equipments used in the SCNU. The
unit must have one pediatrician, independent senior resident doctor and one junior resident round- the- clock for
every 8 babies requiring special care. A laboratory technician should be available to operate bilirubinometer,
glucometer, microcentrifuge, CPR kits and blood gas analyzer. The resident staff and nurses working in the
NICU must be trained to properly handle and use the equipment. When ventilator facilities are established
respiratory therapist is a useful member of the neonatal team to monitor ventilator settings, provide tracheal
suctioning and chest physiotherapy. A pediatric pathologist, who is specially trained for conducting and
interpreting neonatal autopsies, is desirable to complement the functioning of the neonatal team.
EQUIPMENT:
A neonatal intensive care unit (NICU) can be a confusing place with lots of complicated-looking electronics,
dials, wires, tubes, strange noises, beeps, alarms, buzzers, flashing lights, pressure hoses, and bubbling
cannisters that are confusing to visitors and parents. Here is a sampler of the equipment that is commonly seen
in an NICU. Equipments are very important in NICU, for life saving purpose, sudden care. The maintenance of
the existing equipments in proper working condition is more important than acquiring new and sophisticated
gadgets. Date of installation and expiry of warranty period should be recorded. Photocopies of working and
service manuals should be available in the NICU while original documents should be kept in a safe custody.
Maintain a log book containing postal addresses, telephone and fax numbers of local dealers and suppliers of
equipment.
AIRWAY EQUIPMENT
Pocket mask with oxygen port (should be widely available in all clinical areas)
Self inflating resuscitation bag with oxygen reservoir and tubing (ideally, the resuscitation bag should be
single use – if not, it should be equipped with a suitable filter)
Yankauer suckers
Laryngeal mask airways (sizes 4 & 5), or ProSeal LMAs (sizes 4 & 5), or Combitube (small)
Magill forceps
Lubricating jelly
Laryngoscope handles (x 2) and blades (standard and long blade)
Scissors
Selection of syringes
Oxygen cylinders
Cylinder key
CIRCULATION EQUIPMENT
Defibrillator (shock advisory module and or external pacing facility to be decided by local policy)
ECG electrodes
Tourniquet
DRUGS
Adenosine 6 mg x 10
Adrenaline 1 mg (1:10,000) x 4
Adrenaline 1 mg (1:1,000) x 2
Amiodarone 300 mg x 1
Chlorphenamine 10 mg x 2
Furosemide 50 mg x 2
Hydrocortisone 100 mg x 2
Lidocaine 100 mg x 1
Midazolam 10 mg x 1
GTN spray
Aspirin 300 mg
ADDITIONAL ITEMS
Clock
Gloves/Goggles/Aprons
Audit forms
Large scissors
Alcohol wipes
RESUSCITATION EQUIPMENT: emergency tray should be available in each infant care room of SCNU
containing Ambu bag and mask, infant laryngoscope, tracheal tubes of different sizes, sterile suction catheters,
oral mucus suction traps, and emergency drugs.
Bag and mask resuscitator: self inflating bag of 250- 750 ml capacity is ideal for resuscitation of a newborn
baby. It should be provided with a pop off valve or with facility to attach a pressure gauge. An oxygen reservoir
in the form of a corrugated tube to rubber bladder, help to increase the oxygen concentration to 90 to 100
percent. When self- inflating bag is used without an oxygen reservoir, it delivers 40- 60 percent oxygen because
room air enters the bag with each inflation. A one way valve allows delivery of oxygen at the bag is released so
that the exhaled air cannot re- enter the bag. A peep valve can be attached to the valve assembly to deliver
required PEEP. Face masks (size 0, 1, and 2) should be rigid with a cushioned rim to form a tight air- seal fit on
the face enclosing the mouth and nostrils.
Oxygen and suction facilities: a centralized source of oxygen, compressed air and suction outlet consoles (50
psi) affixed on the wall is ideal. De Lee trap for a single use by self oral suction with 12 Fr. In hospitals,
centralized suction, venture suction and electrical suction machines are used. The suction pressure is regulated
with a pressure dial. Facility should be available for intermittent suction because continuous suction may cause
bradycardial and mucosal damage. The suction pressure should be limited to 60- 80 cm of water (1.0 mmHg =
1-3 cm of H2O). Slow suction devices are used for continuous suction of chest cavity and upper pouch of
infants with esophageal atresia.
Catheters, syringes and needles: Nasogastric polyethylene feeding tubes (Fr. 6and 8), suction catheters,
umbilical vein catheters, small- vein infusion sets (G 23), medications (neoflon), and exchange transfusion sets
should be there in NICU. They are prepacked sterile by a process of gamma- irradiation. This should not be
reused after boiling. Only autoclaved syringes and needles should be used. The availability of liberal supplies of
disposables is crucial for reduction of nosocromial infection.
Feeding equipment: Glass or stainless steel bowls of adequate size (120 ml capacity) should be available in the
nursery for collection of expressed breast milk, mixing and preparing the formula. A hot air autoclaving oven or
a pressure sterilizer should be provided for autoclaving feeding equipment. Storage facility like a refrigerator
should be available in the nursery. The formula room should be equipped with working shelves having
laminated plastic surfaces or preferably these should be made of stainless steel so that can be washed and
cleaned.
Laminar flow system: These systems are useful for safe and aseptic formulation and mixing of drugs,
parenteral aggregate filter is used to filter out bacteria.tow types of system are available. Ina vertical type
system, the air flows from above downwards and it is recommended for use in the NICU. The horizontal flow
type system is used for tissue culture and microbiologic techniques. Ultraviolet light source in chamber is kept
on for 30 minutes before use to make the area of operation free of bacteria. The vertical flow of bacteria- free
filtered air maintains a positive pressure of 15 mm Hg to prevent entry of contaminated air into the chamber.
Weighing machine: Accurate weight record of babies is a sensitive index of their well being and availability of
a sturdy and reliable weighing machine fulfills a fundamental need. A sensitive beam- type weighing scale with
a precision of +/- 10g is useful equipment in the nursery. The change of cross infection should be minimized by
using a sterile paper or a towel over the pan before weighing each infant. Electronic weighing machine also
available.
Bassinets: A variety of bassinets are available for routine use in the nursery. It is desirable to use bassinets,
which can be easily cleaned and are equipped with a locker and head tilting mechanism. The locker can be used
to hold the supplies of an individual baby such as diapers, frocks, sterile gauze, cotton, thermometer, feeding
equipment and drugs etc. plastic Plexiglas’s or fiberglass bassinets with relatively low walls and placed at a
convenient height are desirable for ease of observation and examination of the infant. They can easily clean and
disinfected by antiseptic solutions. Alcohol or organic solvents should not be used to clean the elastic or
Plexiglas’s material due to risk of opacification.
Thermometers: Low reading (30-40° C) rectal thermometer is essential to assess the severity of hypothermia.
The severity of hypothermia in small babies may overlook if only conventional thermometers are used.
Electronic or tele thermometers with skin censors or rectal probes with an accuracy of ± 0.1° C are ideal for
continuous atraumatic monitoring of body temperature. These temperature monitors are also equipped with
acoustic and visual alarms set at a desired low and high temperature. Simultaneous monitoring of core and toe
temperature can provide useful information regarding state of peripheral perfusion.
Oxygen concentrator: oxygen concentrators are being indigenously manufactures and they work both on a
battery and mains. The atmospheric air is passed through a chemical which absorbs all gases except oxygen.
Oxygen air blender with an oxygen analyzer can be interposed to deliver a precise concentration of FiO2 but it
considerably enhanced the price of the device. Oxygen must be warmed (36.0- 36.5 ° C) and humidifier before
administration to the patient.
Oxygen head box: A square shaped box made of transparent or Perspex which can enclose the head of the
infant is useful for administration of higher concentration of material moulded as a single piece without any
joints. It should provided with an adjustable neck port or flexible occluding collar to create an effective seal to
prevent free entry of environmental air.
Oxygen analyzer: This is useful for monitoring ambient oxygen concentration in order to protect the infant
against oxygen toxicity. It helps to regulating the flow rate of oxygen so that desired concentration of oxygen is
delivered to the infant depending upon his clinical condition and oxygen requirements.
Perspex heat shield: heat shield made of perspex or transparent plexiglass measuring 18”×10” ×8” in a dome
shape is a very simple and useful device to reduce the heat loss by radiation and evaporation. The currently
available intensive care incubators are double- walled, which are credited to reduce radiative heat loss by 50
percent.
Radiant warmers are used when a baby is very unstable or extremely premature.
Small babies have a large surface area compared to their volume, and little body
fat, and cannot maintain their own temperature. The overhead arm contains
electric heating elements that are directed down toward the infant. A thermostat
is hooked up to a sensor on the baby's abdomen and adjusts the power of the
warmer up and down dynamically so that it delivers whatever heat is necessary
to keep the baby at the perfect temperature. The shelves attached to the warmer
allow monitors and other equipment to be placed conveniently near to the baby,
the glass side walls prevent the baby from being chilled by drafts, and the open
nature of the radiant warmer allows physicians and nurses to have easy access
to the baby from all sides during the most critical periods.
The pulse oximeter, or "pulse ox," monitors the oxygen saturation of the baby's
blood. It does this by shining light through the baby's skin and measuring the
color of the light that is transmitted. Most of you are familiar with the concept
that red blood is arterial and blue blood is venous; this is another way of saying
that blood which is being pumped by the heart from the lungs to the body and
has a lot of oxygen in it is red, whereas blood that is returning to the heart
through the veins after oxygen has been removed by the body's tissues is blue.
By measuring the transmitted light at certain colors very precisely, the pulse
oximeter can provide an estimate of how much oxygen is in the blood. The
pulse oximeter can be fooled, however, when the flow of blood to the hands and
feet is poor, such as when the baby is cold, or when the baby's blood pressure is
low.
A blood gas machine analyzes a sample of the baby's blood, usually obtained
from an arterial catheter or from a "heelstick," and reports the pH and the level
of oxygen and carbon dioxide. It also calculates values for the bicarbonate
level, oxygen saturation, base deficit, and so on. These values are then used by
the neonatologist, nurse practitioner, or respiratory therapist to adjust the setting
of the ventilator and the oxygen blender. It was not practical to do blood gas
tests on babies until the 1970's, when simple techniques for umbilical arterial
catheterization were developed and blood gas machines appeared that could
perform tests on "micro-samples." Today's blood gas machines can perform a
complete analysis on less then 0.2 cc of blood (less than 1/10 of a teaspoon).
The "lightbox" is the traditional tool for viewing X-rays. Essentially, it's just a
big metal frame with backlights and a translucent plastic face. X-rays are
clipped onto the front of the lightbox and can then be viewed and interpreted by
transmitted light.
In the modern, digital era, films are read on-line and the images can be
manipulated through software to aid interpretation -- the contrast and brightness
can be manipulated, the image can be flipped or rotated, edges can be enhanced,
areas of interest can be enlarged, old images can be retrieved from disk storage
and compared with the new images, etc. Most importantly, an image can be
viewed in more than one place at a time, the neonatologist does not need to wait
for film to be "developed," and each image is stored and backed up
electronically so it cannot be misplaced in the radiology file room or borrowed
and lost.
A transport incubator is used when a sick or premature baby is moved from one
hospital to another -- for example, from a community hospital to a larger
medical center that has a neonatal intensive care unit. In fact, a transport
incubator is like a little self-contained intensive care unit on wheels. It usually
has a miniature ventilator (respirator), cardio-respiratory monitor, IV pump,
pulse oximeter, and oxygen supply built right into its frame. A specially-trained
physician, nurse, and respiratory therapist typically accompany the baby
fhroughout the trip.
back into a normal rhythm. Every neonatal ICU has one of these devices, but
they are rarely used there. Abnormal heart rhythms are quite unusual in babies,
even those babies with several cardiac abnormalities -- arrhythmias are more