Coombs' test is used to detect antibodies that act against the surface of your red blood cells.

The presence of these antibodies indicates a

condition known as hemolytic anemia, in which your blood does not contain enough red blood cells because they are destroyed prematurely. An
abnormal (positive) direct Coombs test means you have antibodies that act against your red blood cells. This may be due to: Autoimmune
hemolytic anemia.

Blood tests: These check to see if you are Rh- or Rh+. The father's blood type and Rh factor may also be tested.

Fetal blood sampling: This test may be done to check your baby's blood type and risk of anemia. Healthcare providers take a sample of your
baby's blood from the umbilical cord. With an ultrasound to guide them, a needle is put through your skin, into your uterus, and into the
umbilical cord.

Ultrasound: This test uses sound waves to show pictures of your baby inside your uterus. Healthcare providers can learn the age of your baby
and see how fast he is growing. The movement, heart rate, and other organs of your baby can be seen. Your placenta (tissue in the womb
connecting the mother and baby) and amniotic fluid may be checked. A Doppler ultrasound may be used in place of an amniocentesis to see the
blood flow in your baby's body. Healthcare providers may use this test to check if your baby has anemia.

TREATMENT

Phototherapy: This is done to help reduce jaundice. Bilirubin lights

Blood transfusions: Blood transfusions may be given through the umbilical cord and after birth to treat severe anemia.

Immunoglobulins: This is an injection of antibodies to help reduce the destruction of red blood cells.

Rhogram (Mother)

Ante - 1500 IU^300 mcg IV/IM (28-30 wks ges.)

Post – 1500 IU IV/IM (72 hrs)

(Baby)

Phototherapy

Conventional P.T.