Which one of the following statements is true about the prognosis of lung cancer?

Select one:
1. 10�20 per cent will be cured
2. Non-small cell lung cancer cannot be cured by radiotherapy
3. Small cell histology is a poor prognostic factor#
4. The median survival of untreated small cell lung cancer is 12 months
5. Adenocarcinomas have a particularly poor prognosis

A 28-year-old woman presented to her primary care doctor with a right breast mass
that persisted through three menstrual cycles. A mammogram was not interpretable
due to dense breast tissue, and an ultrasound showed a 2.5-cm breast mass with
associated left axillary lymphadenopathy. A core biopsy of the breast mass was
obtained, showing invasive ductal carcinoma, grade 3, ER/PR negative, HER2 2+ by
immunohistochemistry, with a FISH ratio of 4.3 and a HER2 copy number of 9.5. She
reports a family history of breast cancer in a paternal aunt at age 35, a history
of a brain tumor in that aunt's child at age 10, and a history of a bone cancer in
a paternal grandmother. She is referred for genetic testing. What is the most
likely genetic abnormality identified?
Select one:
1. BRCA1 mutation
2. BRCA2 mutation
3. APC mutation
4. p53 mutation#
5. PALB2 mutation

Which one of the following statements is true about the pathology of breast cancer?
Select one:
1. Lobular carcinomas are more common than ductal
2. Paget's disease of the nipple is always associated with an underlying cancer#
3. Most are squamous carcinomas
4. LCIS is frequently detected by a mammogram
5. Inflammatory cancers account for 10 per cent of cases

Which of the following statements is INCORRECT regarding large cell neuroendocrine

tumors (LCNEC)?
Select one:
1. Paraneoplastic syndromes are commonly associated with LCNEC.#
2. like SCLC, LCNEC have an aggressive natural history and propensity to
metastasize.
3. LCNEC are treated in the same manner as NSCLC, with the same treatment
algorithm, stage for stage.
4. LCNEC are less chemosensitive than SCLC.:

Surgical management of malignant primary tumors have several components besides

Select one:
1. Tissue biopsy to establish morphological diagnosis
2. Removal of malignant tumor with a clear margin of normal tissue
3. Repair, reconstruction and restoration of function
4. Control of hemorrhage, control of obstructive symptoms, fracture reduction and
fixation#

Which one of the following statements is true about the staging of lung cancer?
Select one:
1. Staging is only undertaken in those being considered for surgery
2. Pulmonary angiography should be performed in all cases
3. Bone marrow trephines are routinely performed
4. PET imaging is of value in those being considered for curative surgery#
5. CT imaging is performed in selected cases
Cancer staging has several purposes. All statements are correct regarding cancer
staging except
Select one:
1. It defines the regional and distant extend of disease
2. It helps to determine optimum treatment and provides prognostic information.
3. All statements are true.#
4. Staging may be clinical, non-clinical and pathological.

External beam radiotherapy is the most common of treatment in clinical use. There
are several types of external beam machines besides:
Select one:
1. Macrovoltage machine#
2. Superficial voltage machine
3. Orthovoltage machine
4. Megavltage machine

Which one of following is true about head and neck cancers

Select one:
1. Laryngeal cancer is more frequent in women
2. Lymph node involvement is rare
3. Squamous carcinomas are most common#
4. No symptoms

In the above 76-year-old gentleman, a PET scan does not reveal any other sites of
metastatic disease and a mediastinoscopy does not reveal the presence of carcinoma
cells in the mediastinal or hilar lymph nodes. What stage is the patient's lung
cancer with 3sm in diameter?
Select one:
1. Stage I#
2. Stage IIA
3. Stage IIB
4. Stage III
5. Stage IV

A 53-year-old woman presents with a palpable mass in the upper outer quadrant of
her left breast. Breast imaging confirms the presence of a 2.0-cm mass, and a core
needle biopsy finds invasive ductal carcinoma, grade 3, ER < 5%, PR < 5%, HER2 IHC
0. She proceeded with breast-conserving surgery and a sentinel lymph node biopsy.
Pathology showed a 2.2-cm invasive cancer with negative margins. A total of two
sentinel lymph nodes were recovered, one of which contained a 0.8-cm
macrometastasis. Adjuvant chemotherapy and radiotherapy are planned. What is the
preferred next step in locoregional management?
Select one:
1. Ultrasound of the axilla to evaluate for residual disease
2. Completion axillary lymph node dissection
3. No further axillary surgery#
4. Completion mastectomy
5. Completion mastectomy with axillary lymph node dissection

Brachytherapy is type of radiotherapy which uses several types of sources besides

Select one:
1. Radioactive source placed directly over superficial tumor of the skin.
2. Intracavitary treatment . This uses radioactive sources (tubes or containers)
placed within a body cavity.
3. Interstitial brachytherapy this uses radioactive needles or wire inserted
directly in the tumor.
4. Enteral treatment with radioactive capsules.#

Which of the following statements is correct regarding pulmonary carcinoid tumors?

Select one:
1. Patients usually present with carcinoid syndrome.
2. Surgery has a curative potential for resectable localized tumors.#
3. Adjuvant chemotherapy is the standard of care following complete surgical
resection.
4. Most pulmonary carcinoids are atypical carcinoids

Which of the following is associated with the highest risk of breast cancer?
Select one:
1. Postmenopausal obesity
2. Dense breasts on mammogram#
3. Postmenopausal estrogen plus progestin therapy
4. Nulliparity

Radical treatment is:

Select one:
1. Treatment that have positive benefits
2. Treatment that which is given with the intent of long-term control or cure for
the patient.
3. Treatment that which is given to improve the quality of life for a patient.#
4. A and C.
5. B and C

Which one of the following best describe follicular carcinoma of the thyroid
Select one:
1. Rapidly growing
2. Best treated with surgery and radioisotope Therapy#
3. High risk spread to liver
4. Associated with poor prognosis

Characteristic features of BRCA1-associated breast cancers include the following

except:
Select one:
1. Aggressive features
2. Estrogen receptor (ER) positive#
3. HER 2 negative
4. Young age at presentation

Which of the following statements is/are CORRECT regarding molecular abnormalities

observed in lung cancer?
Select one:
1. Chromosomal translocations have not been seen in NSCLC.
2. C-Kit expression is seen in most NSCLCs.
3. Chromosome 3p allele loss is one the most common events in lung cancer
pathogenesis.#
4. All of the above.
Risk factors for the development of NSCLC (Non-Small Cell Lung Cancer) include:
Select one:
1. Obesity
2. Genetic susceptibility
3. Family history
4. Diet
5. Occupational radon exposure#

Which of the following statements are true about mesothelioma?

Select one:
1. There is associated with asbestos#
2. Presents with heamoptysis.
3. Chemotherapy is mainstay of treatment
4. Distant metastases are uncommon