DRUG STUDY #1

DRUG ORDER MECHANISM OF INDICATION SIDE EFFECTS Dose NURSING RESPONSIBILITTIES

ACTION (why given to client)
Generic Name:  Before Administration:
Methergin Prevention and treatment of Hypertension or 1 mL, 0.2 mg, after - Check the dosage and expiration date.
Methylergometrate ↓ postpartum and hypotension, nausea, delivery of the - Take thorough history assessment
Maleate Stimulates uterine postabortion hemorrhage vomiting, chest pain, anterior shoulder, especially allergy and contraindication on
Brand Name: smooth muscles caused by uterine atony or dyspnea, headache, after delivery of the drug.
↓ subinvolution hematuria, placenta, or during the - Verify and validate client’s identity by
Methergine producing sustained thrombophlebitis, puerperium. May be checking their ID bands.
contractions water intoxication, repeated as required, - Perform handwashing.
↓ hallucinations, leg at intervals of 2-4
thereby shortens the cramps, dizziness, hours. During Administration:
third stage of labor tinnitus, nasal - Observe for signs of local inflammation.
congestion, diarrhea, - Apply pressure to the injection site to
diaphoresis, prevent further bleeding
palpitations, foul
taste. After Administration:
- Dispose of used materials properly.
-Warn patient about adverse reactions.
Tell the patient to report severe reactions
promptly.
- Do proper documentation.
Classification CONTRAINDICATIONS ADVERSE EFFECTS
PC: Ergot Alkaloid and Hypertension. Toxemia. Cardiovascular:
Derivative Pregnancy (Cat.C). hypertension,
TC: oxytocic, lactation temporary chest pain,
stimulant palpitation
CNS: Hallucinations,
dizziness, seizure,
headache
Gastrointestinal:
Nausea, vomiting,
diarrhea, foul taste
Local:
Thrombophlebitis
Otic: Tinnitus
Renal: Hematuria
Respiratory: Dyspnea,
nasal congestion
Miscellaneous:
Diaphoresis
 DRUG STUDY #2

DRUG ORDER MECHANISM OF INDICATION SIDE EFFECTS Dose NURSING RESPONSIBILITTIES

ACTION (why given to client)
Generic Name: Oxytocin  Before Administration:
↓ Induction of labor at term; Redness or irritation I.V.: 10-40 units by I.V. - Check and verify with doctor’s order.
Oxytocin Causes potent and control of postpartum at the injection site, infusion in 1000 mL of - Check the expiration date.
selective bleeding; adjunctive therapy loss of appetite, intravenous fluid at a - Take thorough history assessment
stimulation of uterine in management of abortion nausea, vomiting, rate sufficient to especially allergy and contraindication on
Brand Name: and mammary gland cramping, stomach control uterine atony drug.
smooth muscles pain, more intense or
Pinotocin ↓ more frequent During Administration:
producing sustained contractions (this is an - Monitor vital signs carefully during IV
contractions expected effect of administration.
↓ oxytocin), runny nose, - Give direct IV doses slowly over 1-2
Induces labor and milk sinus pain or irritation, minutes.
ejection and reduces or memory problems. - Inform the patient/watcher and explain
post partum bleeding the indication of drug.

After Administration:
- Dispose of used materials properly.
- Educate the patient about side effects.
- Do proper documentation.

Classification CONTRAINDICATIONS ADVERSE EFFECTS

Oxytocic hormones > Contraindicated in Cardiovascular:
patients hypersensitive to hypertension;
the drug or any of its increased heart rate,
component.
> Also contraindicated in
cephalopelvic disproportion
or delivery that requires
conversion, as in tranverse
lie; in fetal distress when
delivery isn’t imminent; in
prematurity and in severe
toxemia, hypertonic uterine
patterns, total placenta
previa or vasa previa.
> Also contraindicated in
fetal distress.
systemic venous
return, and cardiac
output, and
arrhytmias CNS:
seizures, coma from
water intoxication
Gastrointestinal:
Nausea, vomiting, GU:
titanic uterine
contractions,
abruption placentae,
impaired uterine
blood flow, pelvic
hematoma
Hematologic:
afibrinogenemia
Respiratory: anoxia,
asphyxia