Total No. of Questions : 8] [1] [Total No.

of Printed Pages : 2

Roll No ..................................

MCA-505(C)
M.C.A. V Semester
Examination, December 2020
Bioinformatics
(Elective-III)
Time : Three Hours
Maximum Marks : 70
Note: i) Attempt any five questions.
ii) All questions carry equal marks.
iii) Make diagrams wherever necessary.

1. a) Explain how gene expression monitoring is done?

b) What are the differences between genomics and
proteomics?
14

2. Write short notes on any four: 14

a) CDNA
b) MEDLINE
c) ORACLE
d) JAVA
e) Unigenes

3. What are the fundamentals of bioinformatics and information

technology? Make a detailed introduction to bioinformatics.
14

4. What are protein information resources? How they are

different from genome information resources? Make an
introduction to DNA sequence analysis. 14
MCA-505(C) PTO
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5. What are pair wise alignment techniques? How they are

different from multiple sequence alignment? Why bother
with secondary database searches? What is a secondary
database? 14

6. What are bioinformatics tools? How can you visualize a

sequence data? How can you build a sequence search
protocol? 14

7. What are analysis packages? Make an introduction to analysis

packages. What is there in an analysis package? What is a GCG
(Genome Computing Group) package? 14

8. a) What are the applications and commercial aspects of

bioinformatics? Describe in brief what is macro
molecular modeling and chemo informatics?
b) What is Perl programming? How can you do data
manipulation and file maintenance?
14

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MCA-505(C) PTO