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SUPERFICIAL FUNGAL

INFECTIONS
Putu Anggia Dimitri Pramesti
1770121078
SGD 5
Journal Reading
1. Ravindranath, S., 2016. Pityriasis Versicolor: Therapeutic Efficacy of
Various Regimes of Topical 2% Clotrimazole Cream, Oral
Flucanazole and Ketoconazole. International Journal of
Contemporary Medical Research, 3(8).
2. Matur, M. et al., 2019. Dermoscopic Pattern of Pityriasis Versicolor.
Clinical, Cosmetic and Investigational Dermatology, Volume 12, pp.
303-309.
3. Sharma, Y., Jain, S., Chandra, K. & Munegowda, K., 2016. A
Clinico-Epidemiologic Evaluation Of Pityriasis Versicolor From A
Government Hospital, India: Conventional Methods-Still A Thumbs
Up?. Indian Journal of Medical Sciences, Volume 68.
Introduction
• Pityriasis versicolor is a chronic superficial fungal
infection caused by Malessizia furfur1.

• Clinical findings : hyperpigmented or


hypopigmented, round to oval lesions commonly
found on the trunk, upper arms and face2.

• Treatments : Clotrimazole, Flucanazole and


Ketoconazole1.
Method
1. Patients were treated with various regimes consisting of
topical clotrimazole cream, oral fluconazole and
ketoconazole. Results were recorded after a period of one
month.
2. Dermoscopic images of PV lesions located on different
body sites were retrospectively evaluated.
3. Patients suspected of having superficial mycoses were
evaluated clinically and diagnosis was confirmed
mycologically (skin scraping and microscopic
examination)
Result

Treatment Clinical Cure


Tropical clotrimazole cream (one month) and 86%
fluconazole 400mg single dose
Topical clotrimazole cream (one month) and 73%
fluconazole 150mg (weekly, 4 weeks)
Tropical clotrimazole cream (one month) 73%

Fluconazole 400mg single dose 36%

Ketoconazole 400mg single dose 32%


Result

Dermoscopic features of typical hypopigmented


lesion of pityriasis versicolor
Result
• Highest prevalence of pityriasis versicolor was seen in
patients within age group 21-30 years (38.88%).

• Prominent locations of lesion on the patient’s body were as


follows: Trunk (80.5%), scalp (5.5%), and arm (5.5%).

• Morphologically, most lesions were hypopigmented macules


in 30 patients (83.33%).
Conclusion
• Fluconazole 400mg single dose + topical clotrimazole cream
(one month) is the most effective regime.

• The microscopic method (KOH) is more sensitive for fungi


identification (sphagetti and meatball appearances in
pityriasis vesicolor).

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