"EVERY YEAR MORE

THAN 8,000 PATIENTS

ORGAN
DIE WAITING ON A
TRANSPLANT LIST,
CLONING
THAT IS ON AVERAGE How can a functional
organ be cloned, what
22 PEOPLE PER DAY"
are some of the benefits
ACCORDING TO to organ cloning, and

DONATE LIFE CONTACT US how do we know is it

possible?
AMERICA. mcaffeetaz@gmail.com
www.taziamcaffee.weebly.com
www.taziamca.weebly.com

HOW?
HOW CAN A FUNCTIONAL ORGAN
BE CLONED?
“Stem cells have the capacity to proliferate and
to differentiate into relatively mature cells of
various types,” said Marilia Cascalho, Associate
Professor of Surgery and Associate Professor of
Microbiology & Immunology at University of
Michigan.
Embryonic stem cells can become any cell in the
body. This means they could turn into a muscle
cell, a bone cell, or a tissue cell. For example, if
we wanted to make a liver, we could use stem
cells and turn them into liver cells by implanting
them into other types of cells called blastocysts.
Blastocysts are cells of an embryo, which would
help grow and transform the stem cells into the
specialized desired cell. In this case, they would
transform into liver or kidney cells.
With cloning, they could use somatic cell nuclear
transfer (SCNT). SCNT is using a donated egg
(oocyte) with a removed nucleus and inserting
the patient's nucleus. This could potentially make
it genetically the same as the tissue, resulting in
the tissue recognizing it as its own. This would
then prevent rejection of the functional organ
that grew from the oocyte.
BENEFITS?
ORGAN CLONING VS. ORGAN
TRANSPLANTATION, WHAT ARE
POSSIBILITY?
THE BENEFITS?
HOW DO WE KNOW IT IS POSSIBLE
“The gap between the numbers of livers donated
and the number of patients who would benefit
IF IT HASN'T BEEN DONE BEFORE?
from treatment is, however, also growing.
Theoretically, organ cloning is possible. This is
Therefore, more patients are dying while waiting
because we have already used SCNT to create a
for a suitable liver or are being permanently
life. Dolly the sheep was the first mammal cloned
withdrawn from the waiting list. Because of the
from a human somatic cell using the process of
increased waiting time, patients become sicker,
nuclear transfer. Dolly was the only lamb that
so that when a graft does become available,
survived adulthood out of the 277 test subjects,
their chances of survival are lessened and the
making it an amazing advancement for
need for long hospital stay increases.”
medicine. She was grown in an artificial womb
and lived on to adulthood.
When cloning organs, you wouldn’t have to wait
for someone to die with the same blood type and
She was cloned from a human somatic (stem)
other matches. This could shorten the
cell, which is essentially the same process we
transplantation lists greatly and help more
would use to clone organs. This process is far
people heal. The biggest benefit to organ cloning
from perfect, but with more research scientists
is the elimination of the risk of rejection. The five
can get closer to understanding this process and
year survival rate after liver transplants is 75%.
eventually cloning organs.
Meaning that 25% of patients reject the liver or
die of another cause.
This will lead to saving lives, and that is the
ultimate goal of healthcare. Aeger Primo is the
Even if the patient did not reject the organ
motto healthcare professionals live by, and it
initially, anti-rejection medications must be taken
means The Patient First.
for the rest of the patient’s life. With cloned
organs, our body's white blood cells won’t fight
the new organ because it has the same genetic
makeup. As a result, patients will not have the
burden of taking medication that weakens their
immune system their whole life.