Drug Name Dosage Mechanism of Indication Contraindication Adverse Effect Nursing Consideration

Action
Generic Name: Dose: Exhibits anti- Treatment of a  Hypersensitivity to CNS: seizures  Patient monitoring
Cefuroxime 750mg inflammatory, variety of penicillins or (high doses).  Monitor patient for life-
analgesic, and infections clavulanate threatening adverse effects,
Brand Name: Frequency: antipyretic action including:  History of GI: clostridium including anaphylaxis, Stevens-
Ceftin PRN due to inhibition of Urinary tract amoxicillin/clavula difficile-associated Johnson syndrome, and
COX-2 enzyme. infections, nate-associated diarrhea (CDAD), pseudomembranous colitis.
Pharmacologic Route: Intra- cholestatic jaundice diarrhea, hepatic  Monitor neurologic status,
Class: Second intravenous abdominal and dysfunction, particularly for signs of
generation gynecologic Use Cautiously in: nausea, vomiting. impending seizures.
cephalosporin infections.  Severe renal  Monitor kidney and liver function
insufficiency Derm: rash, test results and intake and output.
Therapeutic  Infectious urticaria.  Monitor CBC with differential
Class: Anti- mononucleosis and prothrombin time; watch for
infective (risk of rash) Hematocrit: blood signs and symptoms of blood
 Hepatic dyscrasias. dyscrasias.
impairment (dose  Monitor temperature; watch for
cautiously, monitor others: allergic signs and symptoms of
liver function) reactions including superinfection.
anaphylaxis and  Monitor CBC, electrolyte levels,
serum sickness, creatinine clearance, occult fecal
superinfection blood test, and liver function test
results every 6 to 12 months.
 Patient teaching
 Advise patient to immediately
report bloody stools, vomiting of
blood, or signs or symptoms of
liver damage (nausea, fatigue,
lethargy, pruritus, yellowing of
eyes or skin, tenderness in upper
right abdomen, or flulike
symptoms)
 Tell patient to avoid aspirin and
other NSAIDs (such as ibuprofen
and naproxen) during therapy.
 As appropriate, review all other
significant and life-threatening
adverse reactions