e Abbott AXSYM° SYSTEM Operations Manual Addendum e ‘ List Number 02J25-02 ©2001 Abbott Laboratories Abbott Laboratories Abbott Park, IL 60064 AXSYM is a Registered Trademark {65583-102 September, 2001 of Abbott Laboratories Patents PendingOperations Manual Addendum Foreword Customer Support Intended Use Your AXSYM® System represents advancements in immunoassay testing and laboratory instrumentation. It is extremely important to us that you operate and maintain the system safely, efficiently, and confidently. To this end, we offer customer support in several form + This addendum is designed to be used in conjunction with the current AXSYM System Operations Manual. Please examine it carefully and become familiar with its contents. + Technical assistance is available. This gives you access to our specially trained staff of Abbott Customer Support Specialists and Field Service Representatives. ‘Together we can make sure this outstanding system achieves its full potential in your laboratory. Contact your Area Customer Support. The Abbott AxSYM System is a fully automated Immunoassay analyzer designed to perform Microparticle Enzyme Immunoassay (MEIA), Fluorescence Polatization Immunoassay (FPIA), Radiative Energy Attenuation (REA) Assay Technology, and fon Capture (IC) Immunoassay Technologies. The AxSYM System performs random access, continuous access, and STAT processing of both large and small molecular weight analytes. The Abbott AxSYM System is designed for the performance of routine immunoassays and analyte determinations such as those required by hospitals and reference laboratories. Proprietary Statement AXSYM System software programs and system documentation are protected by copyright. All rights are reserved. ‘The software and manuals were developed solely for use with Abbott Laboratories equipment, for in vitro diagnostic applications as specified in the operating instructions. ABBOTT AxSYM® System Operations Manual Addendum 65583-102 September, 2001Operations Manual Addendum e Copying or otherwise reproducing these materials, including computerization, for other than archival purposes is prohibited without the prior written consent of Abbott Laboratories. Pictorial Disclaimer The sample printouts/screens and other graphics contained in this manual are for information and illustration purposes only. Abbott Laboratories makes no representations or warranties about the accuracy and reliability of the information on the printouts/ screens and graphics. This information is not to be used for clinical or maintenance evaluation. Abbott Instrument Warranty (U.S. customers only) Abbott Laboratories (Abbott) warrants the AxSYM@® System (System) to be free from defects in workmanship and materials for use by the original purchaser, excluding items subject to wear and tear which require replacement during normal use as a matter of course. This warranty shall continue for a period of one (1) year commencing twenty-one (21) days from the date of system e shipment, referred to as the Warranty Period. If a defect should occur during the Warranty Period, the purchaser must contact the Abbott Customer Support Center immediately and provide details. This warranty does not cover defects or malfunctions which are not reported during the Warranty Period, or which result from any of the following: * Use of any vessel, reagent, or system disposable not supplied by Abbott * Reuse of any system disposable * Chemical decomposition or corrosion + Failure to comply with any requirement or instruction in the current System Operations Manual + Repair or modification without prior Abbott authorization + Negligent or intentional abuse or misuse of the System ABBOTT AxSYM® System Operations Manual Addendum i 65583-102 September, 2001Operations Manual Addendum Liability for all matters arising {rom the supply, installation, use, repair and maintenance of the system, whether arising under this warranty or otherwise, shall be limited solely to the repair or, at Abbott's sole discretion, replacement of the System or components. Replaced parts shall become the property of Abbott. In no event shall Abbott be liable for injuries sustained by third parties, for incidental or consequential damages, ot for lost profits. ‘THE ABOVE IS THE SOLE WARRANTY MADE BY ABBOTT REGARDING THE SYSTEM, AND ABBOTT SPECIFICALLY DISCLAIMS ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED, INCLUDING THE IMPLIED WARRANTIES OF MERCHANTABILITY AND OF FITNESS FOR A PARTICULAR PURPOSE Safety Agency Approvals ‘This equipment has been tested and found to comply with: * Part 15 of the FCC rules for radiated emissions + EN 550114 for radiated and conducted emissions * EN 0082-1 for power line voltage fluctuation immunity * TEC 801-1 for general electro-magnetic compatibility * IEC 801-2 for electrostatic discharge * TEC 801-3 for radiated susceptibility * IEC 801-4 for electrical fast transients * TEC 801-5 for power line voltage surges * IFC 801-6 for conducted radio frequency immunity Trademark Statement AXSYM isa registered trademark of Abbott Laboratories. REA isa registered trademark of Abbott Laboratories. ¥ ‘ABBOTT AxSYM® system Operations Manual Addendum 6583-102 September, 2001SECTION 1: Use or Function e SECTION 1: Use or Function Overview The Abbott AxSYM System is a random and continuous access immunoassay analyzer capable of processing tests using proven technologies. ‘This section presents information on: * The basic function of the AxSYM System * The four main areas of the AxSYM System, the components in each area and their functions * Consumables used with the AxSYM System: + Reagents used with the AxSYM System, * Doors, panels, and covers of the AxSYM System ‘The Abbott AXSYM System uses three different assay technologies: + MEIA (Microparticle Enzyme Immunoassay) A heterogeneous technology used for high and low molecular weight analytes + FPIA (Pluorescence Polarization Immunoassay) @ A homogeneous technology used for low molecular weight analytes + REA (Radiative Energy Attenuation) A homogeneous technology used for low molecular weight analytes For more details on the assay technologies, refer to Section 3: Principles of Operation, Subsection: Assay Technologies. ‘The AXSYM System can process tests with total protocol flexibility and allows assays to be optimized for both performance and ‘throughput. Continuous and STAT testing capability is achieved by separating the sampling area from the test processing area. All areas ate controlled by the same software, yet operate independently of one another. This makes it possible to add or remove samples, reagents, and most of the consumables at any time without interrupting tests in process. ABBOTT AxSYM@ System Operations Manual Addendum ry 65583-102 September, 2001SECTION 1: Use or Function Software e Table 1.3: Screen Descriptions ‘Screen Name Access Path Purpose Log On Select F6- LOGON _| Limits or enables access to certain system func from the Main Menu | tions an configuration parameters. For more details, refer to Section 5: Operating Instructions, Subsection: Log On. Stored Results Select VIEW STORED | This screen displays patient test results that have RESULTS trom the been reviewed, released, and stored. Up to 1600 Stored Results (menu) | results can be stored. When capacity is reached, screen. the oldest resus deleted to make room for anew ‘result NOTE: The system software stores results based upon a date stamp. The software performs a firstin-first-out record deletion based Upon the date stamp of the result record. The date stamp is created from the AxSYM system clock value at the time the result record is created, For mote deals, rel to Section 8: Operating Instructions, Subsection: Reviewing Informa: e@ tion Stored calibration curve information is viewed through the Calibration Review screens. Stored control results are viewed through the Stored QC Results screen or the Levey-Jennings. QC screens. Consumables and Components CAUTION: ‘Wear safety glasses, gloves, anda lab coat when handling AxSYM Probe Cleaning Solution. A Contact with eyes may cause mild irritation in sensitive individuals. Should contact occur, flush affected area with copious amounts of water. If irritation persists, see a physician, z ABBOTT AxSYM@ System Operations Manual Addendum 6583-102 September, 2001Section 2: Installation Procedures and Special Requirements e Section 2: Installation Procedures and Special Requirements Site Preparation Table 2.1: Environmental and Electrical Requirements Dimension Length 63" (160 em) Width 99.5" (85 om) Height 61" (155 om) to top of monitor System Preparation Label Placement ‘Segment Letter Code Label Placement The location of the Letter Code Label is different for each type of Sample Segment, + Sample Cup Segment Label is applied to the back, right corner e ‘+ Primary and Aliquot Tube Segment Label is applied to the front, right corner + Multi-segment Label is applied to the front, right corner For a description of Sample Segment types and use, refer to Section 1: Use or Function, Subsection: Hardware. To place the label onto the segment: 1, Place the Sample Segment upright on a flat surface, 2. Locate the raised plastic guide on the top surface. + Sample Cup Segment Plastic guide is in the back, right corner + Primary and Aliquot Tube Segment Plastic guide is in the front, right corner + Multi-Segment Plastic guide is in the front, right corner “ABBOTT AxSYM@ System Operations Manual Addendum 3 165583-102 September, 2001Section 2: Installation Procedures and Special Requirements nbs Segment Letter Code Label ‘Sample Cup ‘Segment Letter Code Label Multi-Segment Letter Code Label Figure 2.8: Applying Letter Code Label 3. Before applying the Letter Code Label, position it in the center of the raised plastic guide. Be sure that the letter on the Letter Code Label matches that on the Sample Segment Bar Code Label. 4. Lay the label on the segment and carefully press down. 5. Inspect the label for proper alignment. 6. Firmly press down on the label to secure it. 7 ‘ABBOTT AxSYM® System Operations Manual Addendum (65583-102 September, 2001Section 2: Installation Procedures and Special Requirements e System Configuration Assay Parameters Configuration Table 2.6: Assay Parameters Description # | Configuration item | Setting Explanation 6 | Abbrev Assay Name ‘Abbreviated name of the assay in the {Language} selected language. This name appears on the Assay Parameter screen and printed report. This name appears on all printed test reports, on the Contiguration/ Insiallation screen and on the Patient ‘Orders, Control Orders, and Calibration | Orders screens, Control Configuration Control Parameter Description e Control Mean> + The target mean concentration for this analyte + Range allowed is -9999,99 - 999999.999 ABBOTT AxSYM@ System Operations Manual Addendiam 3 (65583-102 September, 2001Section 3: Principles of Operation Section 3: Principles of Operation e No changes z ABBOTT AxSR® System Operations Maal Adem 65583-102 September, 2001Section 4: Performance Characteristics and Specifications e Section 4: Performance Characteristics and Specifications Overview Table 4-2: Physical Specifications Dimensions ength a" (160 em) Wiath 33.5" (85 em) Height 61" (155 em) 10 top of monitor ‘ABBOTT AxSYM® System Operations Mamual Addendum 65583-102 September, 2001Section 5: Operating Instructi ions Loading Samples, Cal Handling Samples. Section 5: Operating Instructions Is, and Controls Loading Primary Tubes 1 Prior to loading a Primary Tube into a Sample Segment, hold the tube up to the Sample Gauge label (on the segment) and verify that the top of the tube is at or below the “Top of Tube” line. NOTE: For instructions on how to apply the Sample Gauge labels to the Sample Segments, refer to the instructions that accompany the Sample Gauge labels. On the Primary Tube Segment Sample Gauge Label, the Minimum Clot/Gel Height Line is as far down as the Sampling Probe can travel in that segment. ‘The actual Clot/Gel height can be higher or lower than that line as long as there is: ‘+ aminimum of one-half inch of sample above the Clot/Gel ‘+ enough sample volume as defined in the AxSYM Assay- specific Package Insert + enough sample above the Minimum Clot/Gel Height for sample aspiration If using an Aliquot Tube Segment, verify that the Clot or Gel Height is at or above the “Minimum Sample Height” line. Verify that the serum/plasma sample height is at least 1/2” above the Clot or Gel Height to ensure that the probe will not aspirate red cells, gel, fibrin, or particulate matter (assuming, the tube has been handled and centrifuged according to the tube manufacturers’ instructions). Verify that the minimum sample volume requirement listed in the AXSYM Assay-specific Package Insert is followed. If the sample meets the above requirements, carefully load it into the sample segment making sure that the bar code label is facing the inner curve of the sample segment and does not extend beyond the opening in the segment. NOTE: If the bar code label is not properly placed on the sample tube, then the read may be unsuccessful. After three unsuccessful reads of a bar code label, the Sampling Center will stop. ABBOTT AxSYM® System Operations Manual Addendum (65583-102 September, 2001Section 5: Operating Instructions 1 e Loading Aliquot Tubes Prior to loading an Aliquot Tube into a Sample Segment, hold the tube up to the Sample Gauge label (on the segment) and verify that the top of the tube is at or below the “Top of Tube” line. NOTE: For instructions on how to apply the Sample Gauge labels to the Sample Segments, refer to the instructions that accompany the Sample Gauge labels. Verify that the sample height is at or above the “Minimum Sample Height” line. Verify that the minimum sample volume requirement listed in the AXSYM Assay-specific Package Insert is followed. If the sample meets the above requirements, carefully load it into the sample segment making sure that the bar code label is facing the inner curve of the sample segment and does not extend beyond the opening in the segment. NOTE: if the bar code label is not properly placed on the sample tube, then the read may be unsuccessful. After three unsuccessful reads of a bar code label, the Sampling Center will stop. e Aliquot and Primary Tubes If a Segment/Position has not already been assigned, Aliquot or Primary tube samples with Bar Code Labels may be placed in any Segment/Position If your system is configured Positive Sample ID> OFF and Auto Assign Locations> ON, the system automatically assigns the Segment/Position. Refer to the Orderlist screen or print the Orderlist Report to load the sample by segment and position If your system is configured Auto Assign Locations> OFF or if you choose to override the auto assign, refer to the Orderlist screen or print the Orderlist Report to load the samples in the correct Segment/Position. ‘ABBOTT AxSYM® System Operations Manual Addendum {65583-102 September, 2001Section 5: Operating Instructions Aliquot Primary Tube Tube Figure 5.27: Load Aliquot and Primary sample tubes into Sample Segment For details on printing the Orderlist screen or report, refer to Printing within this section. 1, If the system status is RUNNING, press the blue PAUSE Button to pause the Sampling Center. e@ 2. Wait for the Sampling Center to come to a complete stop, the system status field to display PAUSED, and the Sampling Center Motion Detection Light to go out. 3. Remove the Sample Carousel Cover. 4. Load the segments onto the Sample Carousel in any empty position. NOTE: Press the green Advance Carousel button on the Sampling Center to access empty Reagent Pack Carousel positions. Sample segments are processed by their Sample Carousel position. Lower carousel positions are sampled first. ‘CAUTION: Wait for the carousel movement to complete before pressing the Advance Carousel button A again. A system lockup may occur if the Advance Carousel button is pressed multiple times without allowing the movement to complete. 5. Replace the Sample Carousel Cover. w ABBOTT AxSYM@ System Operations Manual Addendum 65583-102 September, 2001Section 5: Operating Instructions Pause Button (blue) Carousel Advance Button (green) Figure 5.28: Load sample segment into Sample Carousel Sample Cup Adaptor Review the warnings and cautions associated with handling samples and loading sample vessels and sample segments before performing this procedure. Sample cup adaptors can be used to place sample cups into Primary ‘Tube Segments, Aliquot Tube Segments or Multi-Segments. 1, Transfer patient sample volume into sample cup with adaptor. NOTE: Be sure to transfer enough sample into the sample cup to run automatic retests, multiple tests or assays on a sample if needed. Do not exceed the maximum Sample Cup capacity of 2 mls. 2. Place the sample cup with the appropriate adaptor into a Sample segment making sure the Bar Code Label is facing the inner curve of the sample segment. ‘NOTE: Be sure to use Primary Sample Cup Adaptors with Primary Tube Segments and Multi-Segments. Use Aliquot Sample Cup Adaptors with Aliquot Tube Segments. NOTE: Do not place Sample Cup Adaptors in positions 1- 5 of a Tube Segment if that Tube Segment will be adjacent (counterclockwise) to a Multi-Segment in the Sample Carousel. ‘ABBOTT AxSYM® System Operations Manual Addendum 11 65583-102 September, 2001Section 5: Operating Instructions Sample Cup Adaptor ‘Segment Figure 5.31: Load sample cup adaptor 3. If the system status is RUNNING press the blue PAUSE Button to pause the Sampling Center. 4. Wait for the Sampling Center to come to a complete stop, the system status field to display PAUSED, and the Sampling Center Motion Detection Light to go out. 5. Remove the Sample Carousel Cover. 6. Load the segments onto the Sample Carousel in any empty position. ‘NOTE: Press the green Advance Carousel button on the Sampling Center to access empty Reagent Pack Carousel positions. Sample segments are processed by their Sample Carousel position. Lower carousel positions are sampled first. CAUTION: Wait for the carousel movement to complete before pressing the Advance Carousel button A again, A system lockup may occur if the Advance Carousel button is pressed multiple times without allowing the movement to complete. 7. Replace the Sample Carousel Cover. 2 ABBOTT AxSYM@® System Operations Manual Addendum {65583-102 September, 2001Section 5: Operating Instructions Figure 5.32: Load sample segment Loading Calibrators and Controls Review the warnings and cautions associated with loading reagents, controls and calibrators before performing this procedure NOTE: Be sure to load calibrators in the correct order A For M-l, M-2, etc.). 1, Select the assigned sample segments. 2. Place the appropriate sample cup adaptors into the segment positions assigned on the Orderlist. NOTE: This step is not necessary if you are using sample cup segments, NOTE: Do not place Sample Cup Adaptors in positions 1- 5 of a Tube Segment if that Tube Segment will be adjacent (counterclockwise) to a Multi-Segment in the Sample Carousel. ‘ABBOTT AxSYM® System Operations Manual Adilendum 13 65583-102 September, 2001Section 5: Operating Instructions Cup = 4 e Sample Cup Adaptor Sample Cup Segment Tube Segment Figure 5.34: Insert Sample Cups 3. Load the appropriate number of sample cups into the sample segments according to the Orderlist screen or Orderlist Report. BOTT AS System Operations Maral Adder 65583-102 September, 2001Section 5: Operating Instructions Deleting Deleting a Test Result Test orders with a status of RUNNING can not be deleted. A test can be deleted from the following screens: + Results + Order Status ‘+ Exceptions ‘+ Details screen from any of the previous three screens + Stored Results 1. Access the Results, Order Status, Stored Results, or Exceptions screen. Choose one ‘+ Select RESULTS from the Main Menu ‘+ Select ORDER STATUS from the Main Menu ‘+ Select STORED RESULTS from the Main Menu, then select VIEW STORED RESULTS + Press EXCEPTIONS key + Select EXCEPTIONS Indicator (when displayed) e 2. Select the test(s) that you wish to delete. Choose one: + Select one or more individual test(s) ‘+ Select F2- SELECT ALL to select all test orders NOTE: If the details screen is selected, you may select F2- DELETE to delete the test result. If more than one test is, selected in step 2, select F6 — NEXT to review the details of the next selected test order. 3. Select F2 - DELETE. 4, Select YES to confirm delete. ‘+ The system permanently deletes the test from the system records ‘+ Tocancel the delete request, select NO. 5. Return to Main Menu (optional). Choose one: Press Main Menu key + Touch Abbott “A” logo ‘ABBOTT AxSYM® System Operations Manual Addendum 15 (65583-102 September, 2001Section 5: Operating Instructions Releasing e NOTE: The system software stores results based upon a date stamp. The software performs a first-in-first-out record deletion based upon the date stamp of the result record. The date stamp is created from the AxSYM system, clock value at the time the result record is created. Reviewing Information Viewing Messages NOTE: If unable to locate and view a specific message, select ALL from the Find/View screen. 16 ABBOTT AxSYM® system Operations Manual Addendum 6583-102 September, 2001Section 6: Calibration Procedures e Section 6: Calibration Procedures No changes ABBOTT AxSYM@ System Operations Manual Addendum 7 65583-102 September, 2001Section 7: Operational Precautions and Limitations Section 7: Operational Precautions and e Limitations Hazard Types Chemical Hazards AxSYM Probe Cleaning Solution (TEAH) Wear safety glasses, gloves, and a lab coat when handling AxSYM Probe Cleaning Solution. Contact with eyes may cause mild irritation in sensitive individuals. Should contact occur, flush affected area with copious amounts of water. If irritation petsists, see a physician. ‘ABBOTT AxSYM® System Operations Manual Addendum 18 {65583102 September, 2001Section 8: Hazards Hazard Locations General Section 8: Hazards ‘CAUTION: A ‘Wear safety glasses, gloves, and a lab coat when handling AxSYM Probe Cleaning Solution. Contact with eyes may cause mild irritation in sensitive individuals. Should contact occur, flush affected area with copious amounts of water. If irritation persists, see a physician. ABBOTT AxSYM@ System Operations Manual Addendum 9 (65583-102 September, 2001Section 9: Service and Maintenance Section 9: Service and Maintenance e Weekly Maintenance MEIA Verification Procedure NOTE: If the estimated time to completion counts down to zero and then continues to count up, cancel the procedure by pressing the STOP button. Proceed to MEIA Verification Cancelled. FPIA Maintenance Procedure NOTE: If the estimated time to completion counts down to zero and then continues to count up, cancel the procedure by pressing the STOP button. Proceed to FPIA Verification Cancelled. 2 ABBOTT AXSYM® System Operations Manual Addendum 65583-102 September, 2001Section 9: Service and Maintenance e Additional Maintenance Fluidics Check Cuverte Figure 9.78: Pipette 1 mL Fluidics Check Solution into Cuvette "ABBOTT AXSYM@® System Operations Manual Addendum 2 165583-102 September, 2001Section 10: Troubleshooting and Diagnostics Section 10: Troubleshooting and Diagnostics e General 0001-0999 0232 Not able to process test, Tube found in sample cup adaptor position of a Mutti- segment, sample position (#). Probable Cause(s) Corrective Action(s) A tube with a bar code label was Remove the bar code labeled tube. placed in the sample cup adaptor position on the Multi-segment. 0233 The value you have entered for eld is not within the dynamic range of the T-Uptake assay when the selected result concentration unit is % Uptake. Probable Cause(s) Comective Action(s) Ilegal value entered while editing an _Re-edit field using value within the e assay parameter for the T-Uptake acceptable range. assay. B ABBOTT AxSYM@® System Operations Manual Addendum ‘6583-102 September, 2001Section 10: Troubleshooting and Assay Specific e 1000-1999 1128 Invalid test result, not able to calculate PSA ratio. Probable Cause(s) When attempting to calculate the PSA ratio the value of the Total PSA Assay result is 0.0. oR Comective Action(s) Choose one: + Reorder the Total PSA and Free PSA assays. * Reorder the Total PSA assay and manually calculate the PSA Ratio. If the problem is not resolved, call ANSYM Customer Support Center. Not able to process test, dual reagent pack load error. ® Probable Cause(s) A Dual Reagent Pack assay was ordered but a barcoded Reagent Pack was loaded where the non-barcoded secondary Reagent Pack should have been loaded. This can only happen if the Dual Pack has been separated. Conective Action(s) 1, Press the blue PAUSE button. 2, Replace the damaged (separated) Dual Pack with an undamaged Dual Pack For more details, refer to the AXSYM Assay-specific Package Insert. 3. Rescan the Reagent Packs. 4, Rerun the test from the Exceptions list. ABBOTT AxSYM® System Operations Manual Addendum 23 65583-102 September, 2001Section 10: Troubleshooting and Diagnostics Assay Specific 1000-1999 (Continued) @ 1129 Ratio cancelled, constituent result(s) outsi le acceptability range. Probable Cause(s) Comective Action(s) If one of the assays in a ratio Choose one: calculation was outside of the acceptability range, the ratio will not be calculated. * Reorder the assays required for the tatio calculation. + Reorder the assay that was outside of the acceptability range and manually calculate the ratio. If the problem is not resolved, call AXSYM Customer Support Center. ABBOTT AxSYM@® System Operations Manual Addendum {65583-102 September, 2001Section 10: roubleshooting and Diagnostics Maintenance Errors @ 2000-2999 2608 Temperature set point out of range, air heater, processing center. Probable Cause) = Comective Action(s) During the Temperature Calibration _Call AxSYM Customer Support Center. procedure (ESE function), the cuvette liquid temperature entered was out of the acceptable range. “ABBOTT AxSYM@ System Operations Manual Addendum 3 {65583-102 September, 2001Section 10: Troubleshooting and Diagnostics Observed Problems Test Order shown Running past the estimated time to completion Probable Cause(s) Internal software error. Corrective Action(s . Select F2-SHUTDOWN, . Tum the system power off. . Wait 30 seconds. Tum the system power ON. Select F3-STARTUP. Upon reboot, the test order that appeared as still in the RUNNING status will move to EXCEPTIONS. Rerun the test order, if needed. If the test order continues to show a RUNNING status after cycling power to the instrument, call AXSYM Customer Support Center. System status remains PAUSED following the completion of a run Probable Cause(s) Whille the system was completing a run and the status was PAUSED, a reagent pack for an assay that did not have orders was loaded, and then RUN was pressed. Corrective Action(s) . Verify that ail sample testing is complete. . Press the Stop key . Select F3-STARTUP. If the status remains PAUSED after pressing the Stop key, call AXSYM Customer Support Center. ABBOTT AxSYM® System Operations Manual Addendum (65583-102 September, 2001Section 10: Troubleshooting and Diagnostics e APPENDICES Appendix B Levey-Jennings QC Analysis Report The Levey-Jennings QC Analysis Report consists of raw data used to generate a Levey-Jennings graphical analysis of a control. Levey-Jennings Graph The Levey-Jennings Graph is a trend plot of raw data for a selected control, ‘ABBOTT AxSYM@ System Operations Manual Addendum 27 6583-102 September, 2001: Troubleshooting and Diagnostics cy ABBOTT AxSYM@® System Operations Manual Addendum 65583-102 September, 2001