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2004 JADA Harrel Molinary Aerosols and Splatter
2004 JADA Harrel Molinary Aerosols and Splatter
N
CON
acute respiratory syn-
IO
Aerosols and splatter drome, or SARS, a review
T
T
A
N
I
C
of the infection control U
A ING EDU 1
R
in dentistry procedures for aerosols is
warranted.
TICLE
the “black plague”—the pneumonic form of the SARS recently has been reported in China,
disease was recognized as the most deadly. His- Canada and other countries. This severe flulike
torical accounts have noted that the pneumonic illness appears to be caused by a new form of
form of the plague, characterized by severe coronavirus, a family of viruses usually asso-
coughing, has been spread from patients who had ciated with the common cold. The exact mecha-
the pneumonic form of plague to those who sur- nisms by which SARS is spread remains uncer-
rounded the patient but were not necessarily in tain, but it is clear that the primary method is
direct contact. Apparently, because the bacteria through aerosolized droplets produced by
that cause plague (Yersinia pestis) were inhaled, coughing or other means. In a Hong Kong apart-
the pneumonic form of the disease was reported ment complex outbreak, it appeared that the dis-
to progress more rapidly than other forms of ease may have been spread through ventilation
plague, and historical reports indicate that it was systems by airborne viruses that were indepen-
almost universally fatal.2 dent of larger droplets.5 The Centers for Disease
There are more recent examples of the spread Control and Prevention, or CDC, and the ADA
of disease by an airborne route. In one published have recommended that aerosol-producing pro-
report, a number of people were cedures should be avoided in
exposed to tuberculosis, or TB, patients with active SARS. The
while on a commercial airline flight. The smaller particles ADA has pointed out that it is
A patient with active TB boarded of an aerosol have the unlikely that any dental treatment
an airplane in Chicago en route to potential to penetrate will be performed on a patient with
Honolulu. During the flight, the and lodge in the active SARS, owing to the fact that
patient coughed repeatedly, these patients are extremely ill and
smaller passages of
aerosolizing the tubercle bacillus, should not undergo any elective
which then entered the airplane’s the lungs and are procedures.6,7
ventilation system and subse- thought to carry the
quently spread to other parts of the DENTAL AEROSOL AND
greatest potential SPLATTER
airplane cabin. After it was con- for transmitting
firmed that the patient had active infections. The terms “aerosol” and “splatter”
TB, it was determined that 15 of the in the dental environment were
55 passengers in the cabin who used by Micik and colleagues8-12 in
were tested had been exposed to their pioneering work on aerobi-
TB, as confirmed by a positive tuberculin test. ology. In these articles, aerosols were defined as
Passengers seated within two rows of the source particles less than 50 micrometers in diameter.
patient had a higher probability of a positive skin Particles of this size are small enough to stay air-
test than did those seated elsewhere in the cabin.3 borne for an extended period before they settle on
Another published example occurred in a med- environmental surfaces or enter the respiratory
ical office where the measles virus was spread tract. The smaller particles of an aerosol (0.5 to
through the ventilation system to multiple people. 10 μm in diameter) have the potential to pene-
The source patient was a 12-year-old boy who was trate and lodge in the smaller passages of the
coughing. Of the seven people who had secondary lungs and are thought to carry the greatest poten-
cases of measles that were associated with him, tial for transmitting infections.
three were never in the same room with the Splatter was defined by Micik and colleagues
source patient and one entered the office an hour as airborne particles larger than 50 μm in diam-
after he had left.4 eter. Micik and colleagues stated that these parti-
More common is the apparent spread of cold cles behaved in a ballistic manner. This means
and influenza viruses by airborne routes. How- that these particles or droplets are ejected forcibly
ever, the actual documentation of an airborne from the operating site and arc in a trajectory
route for transmission of cold and influenza similar to that of a bullet until they contact a sur-
viruses is difficult to verify. Because cold and flu face or fall to the floor. These particles are too
viruses can be transmitted by contact, contami- large to become suspended in the air and are air-
nated objects and an airborne route, in a flu out- borne only briefly.
break it often is difficult to know the exact route The consensus has been that the greatest air-
by which the virus is transferred. borne infection threat in dentistry comes from
Both approaches also have the problem that it dental personnel and other patients completely. A
takes an extended period for the air in the treat- single step will reduce the risk of infection by a
ment room to cycle through the filter or UV treat- certain percentage, another step added to the first
ment system. step will reduce the remaining risk, until such
From a practical point of view, it is easiest to time as the risk is minimal. This can be described
remove as much airborne contamination as pos- as a layering of protective procedures. This lay-
sible before it escapes the immediate treatment ering of infection control steps needs to be fol-
site. The use of a high-volume evacuator, or HVE, lowed in reducing the potential danger from
has been shown to reduce the contamination dental aerosols.
arising from the operative site by more than 90 The dental team should not rely on a single
percent.8,23,33-35 It should be emphasized that for a precautionary strategy. In the reduction of dental
suction system to be classified as an HVE, it must aerosols, the first layer of defense is personal pro-
remove a large volume of air within a short tection barriers such as masks, gloves and safety
period. An evacuator that pulls a high vacuum glasses. The second layer of defense is the routine
but does not remove a large volume of air, such as use of an antiseptic preprocedural rinse with a
is used routinely for hospital suc- mouthwash such as chlorhexadine.
tion, is not considered an HVE. The The third layer of defense is the rou-
usual HVE used in dentistry has a No single approach tine use of an HVE either by an
large opening (usually 8 millime- or device can assistant or attached to the instru-
ters or greater) and is attached to ment being used. An additional
minimize the risk of
an evacuation system that will layer of defense may be the use of a
remove a large volume of air (up to infection to dental device to reduce aerosol contamina-
100 cubic feet of air per minute). personnel and other tion that escapes the operating
The small opening of a saliva patients completely. area, such as a HEPA filter. The
ejector does not remove a large first three layers of defense are
enough volume of air to be classi- found routinely in most dental oper-
fied as an HVE. atories, are inexpensive and can be
During restorative dentistry, the HVE often made part of routine infection control practices
will be used by an assistant who is able to guide easily. Unfortunately, many operators appear to
and aim the vacuum in a manner that elimi- use only the first layer of defense (personal pro-
nates or greatly reduces the visible water spray tection barriers) without following the other
produced during dental procedures. It has been simple steps. All three simple and inexpensive
shown that the number of CFUs produced steps should be followed routinely for adequate
during dental procedures is reduced greatly protection. Table 3 lists the available methods of
when an assistant uses an HVE.8 A problem reducing aerosols and splatter contamination, as
arises when the operator is working without an well as their relative effectiveness and costs.
assistant. This often is the case during delivery
of periodontal treatment by a dental hygienist. REGULATORY AND LEGAL CONCERNS
Several options are available to operators The ADA and CDC have recommended that all
working without an assistant. They include blood-contaminated aerosols and splatter should
using the operating instrument in one hand and be minimized.29 Occupational Safety and Health
the HVE in the other hand, HVE devices that Administration regulations state that “all pro-
attach to the operating instrument and various cedures involving blood or other potentially infec-
“dry field” devices that attach to an HVE. For air tious materials shall be performed in such a
polishing and air abrasion, devices are available manner as to minimize splashing, spraying, spat-
that combine a barrier device to help contain the tering, and generation of droplets of the these
abrasive material and a vacuum to remove the substances.”37 In the guidelines for infection con-
abrasive material and the airborne particles cre- trol in dental health-care settings that was pub-
ated by the procedures.28,36 All of these instru- lished recently by the CDC, all of these recom-
ments are available commercially from multiple mendations were retained. The use of rubber
sources. dams and HVEs are considered to be “appropriate
It must be emphasized that no single approach work practices”—precautions that always should
or device can minimize the risk of infection to be followed during dental procedures.38
TABLE 3
Barrier Protection—Masks, Part of “standard precautions,” Masks will only filter out 60 to 95
Gloves and Eye Protection inexpensive percent of aerosols, subject to leakage if
not well-fitted, do not protect when
mask is removed after the procedure
Preprocedural Rinse With Reduces the bacterial count in Tends to be most effective on free-
Antiseptic Mouthwash Such as the mouth, saliva and air; inex- floating organisms; it will not affect
Chlorhexidine pensive on a per-patient basis biofilm organisms such as plaque,
subgingival organisms, blood from the
operative site or organisms from the
nasopharynx
High-Volume Evacuator Will reduce the number of bac- When an assistant is not available, it is
teria in the air and remove most necessary to use a high-volume evacu-
of the material generated at the ator attached to the instrument or a
operative site such as bacteria, “dry field” device; a small-bore saliva
blood and viruses; inexpensive ejector is not an adequate substitute
on a per-patient basis
High-Efficiency Particulate Air Effective in reducing numbers Only effective once the organisms are
Room Filters and Ultraviolet of airborne organisms already in the room’s air, moderate to
Treatment of Ventilation expensive, may require engineering
System changes to the ventilation system
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