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Dr.

Boyd Haley PhD Mercury Exposure: An Alzheimer’s


Disease Alert  How mercury blocks the brain from
functioning properly  Scientific proof that mercury in
silver fillings can cause Alzheimer’s disease  Discover
the best nutrients to safely detoxify mercury from the body;
H: You cannot be absolutely sure someone died of
Alzheimer’s Disease until they do an autopsy on the brain.
They look for 2 or 3 markers and they look for Beta
amyloid plaque, nerve fibrillary tangles, and a hyper-
phosphorylase protein. We have research that shows that
mercury causes all three of them.

JONATHAN: we are hearing of people being diagnosed


with Alzheimer’s? How can they do that?
H: I cannot say that mercury causes all Alzheimer’s disease
but if you are going to get Alzheimer’s during your life,
having dental amalgam and exposure to mercury is going to
quicken that dramatically.

JONATHAN: can you inherit this disease?


H: No; there was a study done on 500 sets of twins from
the WWII era. They followed them to identify what
diseases they had because if they were genetic, both of
them would get it. They found out that Alzheimer’s is not
genetically inherited although you do inherit the tendency
to get it.

When you are working


with humans you cannot take brain biopsies. But they can
see that people that are going to get Alzheimer’s have the
precursors of mild cognitive incompetence that starts in the
20s and 30s. It doesn’t come on in a month or so; the brain
starts breaking down in the 20s and 30s. The synaptic
connections break down dramatically and mercury does
this extremely well. It also causes the synaptic connections
to break down dramatically. It causes the major protein
that holds the axon in the right shape and conformation so
it goes on to the next neuron and so forth.

What we found out


about in 1988 when we looked that the Alzheimer’s (AD)
brain the tubelen was over 80% on the average abnormal
and broken down and not doing what it was supposed to be
doing. The axions that hold in the connections in the
proper orientation had broken down in those brains. We
showed them that mercury and only mercury would case
this breakdown. Later research showed the living neurons
growing and when they put a minus tens which is about
100 times lower than you would find in an AD brain and
you added to the neurons that were growing, they
dissipated. The tubulens completely separated from the
axions and I had seen this earlier in the chemical
measurements.

Since then people in


Korea have researched to show that mercury causes an
increase in Beta amyloid protein. It does this by inhibiting
the enzyme in the brain that is supposed to chew up Beta
amyloid and get rid of it. Their studies show that the
tubulen and axion are inhibited by mercury and this leads to
amyloid plaques. Also hyper-phosphorylation was shown
to be induced by treating neuron cells with mercury. This
was done in Switzerland. They found when you put in
mercury the hyper-phosphorylation of tau which is third
diagnostic hallmark of AD brain occurred very
dramatically.

To make a long story


short we have seen if you look that the abnormal
biochemistry of the tubelen that holds the shape of the
axions and the production of the nerve fibrillary tangles and
the hyper-phosphorylation of tau it is the protein that
connects the tubelen to the neuro fibers and gets displaced
and does not get dephospholated in the proper fashion and
phospholation builds up and then you see there are a lot of
other things that happen. There are enzymes in the brain
that are over 90% inhibited in the AD brain and we have
published that.

The only thing that can


cause the inhibition of these proteins is mercury. One is
called creatine kinase which is very common and is found
in every cell in the body. It is looked for in blood tests for
heart attacks to see if the cells have broken open. It is that
important and you have to have high levels of it and all
high energetic ATP utilizing cells. We found that it is
incredibly sensitive to mercury which will inhibit it and an
AD brain is 98% inhibited and if you add a small amount of
mercury or thimerosol that enzyme is dramatically
inhibited. We can absolutely say that mercury has all the
hallmarks, all the biochemistry that it can induce that leads
to the diagnostic hallmarks for AD and the abnormal
biochemistry that you find in an AD brain.

It is almost a shoe-in. If
there anything other than mercury everybody would be
talking about it. You cannot get a grant from RNIH to look
that mercury as a cause of AD. They won’t even listen to
it and they won’t fund it. I know because I have tried. The
main reason is that our government has the responsibility
for the highest level of mercury in the body of Americans
based upon the approval of mercury amalgams in dentistry
and flu shots.

Some of our
experiments took a single extracted tooth with an amalgam
filling and dropped that in one ml of distilled water and
took some of that water and added it to human brain
samples just like we did with adding mercury and we got
the same exact result as we did when we added mercury.
The mercury was coming out of the dental amalgam and
getting in the distilled water. When we added it that water
had the same properties of inhibiting these key enzymes as
the mercury we bought for the tests. The bottom line is the
amount of mercury that we had to the brain samples to get
that level is much less than was found in the brains of older
people that have died and the mercury levels in their brains
were measured.

JONATHAN: on one hand the FDA and dentistry are all


saying mercury fillings won’t hurt anyone. But when they
take them out they treat it like nuclear waste. There is a
massive disconnect. It’s safe when it is being put in and
highly toxic when it is being taken out and be careful where
you put it.

H: I can’t explain these people and I don’t wake up and


think of what evil things could be done today. But I can’t
think of a more evil thing than putting an amalgam filling
in the mouth of a person. Mercury is an element and you
cannot break it down and you cannot change it. It is
mercury no matter where it comes from. We have shown
and filmed this. Mercury vapor comes off fillings and you
can see this with a mercury lamp. It looks like cigarette
smoke.

You can put a mercury


vapor analyzer and measure it and show it is mercury and
it’s an element that doesn’t break down. It’s easy to
measure and it’s very toxic. I think I’m being too kind to
these people. They are either incredibly stupid or they are
criminals.

JONATHAN: what about the components of a diseased


brain.
H: we know that the synapses between two neurons are
dramatically reduced in AD and mercury will do that
within a few seconds of entering the brain. If you breathe
this from a coal fired power plant or any source it doesn’t
make a difference. It is an element that crosses the blood
brain barrier easier than anything I know of. It is oxydized
from HT0 vapor to HT2+; it goes from it’s non=toxic form
to it’s most toxic form very quickly in the brain and it gets
trapped in the brain and builds up over the years and it
causes the formation and breakdown of the synapses. It
causes the formation of beta-amyloid plaques in the brain.
This is the major diagnostic hallmark.

It was thought this was


the cause of AD and early on in my career I said that they
had no proof it was a cause of the disease. It was a result of
the disease. How you have something spontaneously form
in the brain without there being an induction factor? I had
in my grants for 25 years and never missed a funding cycle
and always got excellent scores from the NIH study
sections that reviewed my grants. When I started doing
mercury everything changed and they tried to say the work
I was doing wasn’t well designed. I challenged them on
that and had a different section study it and I won.

The second group said


the things the first group said that made my work not
credible were totally wrong. The next time I went for a
grant they came back and said that H has to realize that
they have seen enough of this type of research and they
actually triaged. They didn’t criticize the grant and they
didn’t say anything was wrong but they said they didn’t
want to see any more of it. That is how I lost my NIH
funding. At that time there was a man, HP Wallace whose
father was vice president under Harry Truman and he was a
person who invented pioneer seed corn. He was very
intelligent and very wealthy. HP was the same way and he
developed laying chickens that laid eggs that a much
higher rate than normal. HP thought his father died of
mercury toxicity because of sticking his hands in the seed
corn he was planting that had thimerosol on it to keep it
from having fungus grow on it. He funded me for 5 years
and that allowed me to go on with my mercury research
because he wanted to see me accomplish this.

The major damage by


mercury is the neurofibrillary tangles. These are neural
fibers with the tubelen stripped off them. 15.48
http://holisticoralhealthsummit.com/expert/boyd-haley/
Dr. Boyd Haley: Mercury Exposure: An Alzheimer’s
Disease Alert  How mercury blocks the brain from
functioning properly  Scientific proof that mercury in
silver fillings can cause Alzheimer’s disease  Discover
the best nutrients to safely detoxify mercury from the
body;
You cannot be absolutely sure someone died of
Alzheimer’s Disease until they do an autopsy on the brain.
They look for 2 or 3 markers and they look for Beta
amyloid plaque, nerve fibrillary tangles, and a hyper-
osporylase protein. We have research that shows that
mercury causes all three of them.

JONATHAN: we are hearing of people being diagnosed


with Alzheimer’s? How can they do that?
Dr. Haley: I cannot say that mercury causes all
Alzheimer’s disease but if you are going to get Alzheimer’s
during your life, having dental amalgam and exposure to
mercury is going to quicken that dramatically.

JONATHAN: can you inherit this disease?


Dr. Haley: No; there was a study done on 500 sets of twins
from the WWII era. They followed them to identify what
diseases they had because if they were genetic, both of
them would get it. They found out that Alzheimer’s is not
genetically inherited although you do inherit the tendency
to get it.

When you are working


with humans you cannot take brain biopsies. But they can
see that people that are going to get Alzheimer’s have the
precursors of mild cognitive incompetence that starts in the
20s and 30s. It doesn’t come on in a month or so; the brain
starts breaking down in the 20s and 30s. The synaptic
connections break down dramatically and mercury does is
extremely well. It also causes the synaptic connections to
break down dramatically. It causes the major protein that
holds the axion in the right shape and conformation so it
goes on to the next neuron and so forth.

We found out about in


1988 when we looked that the Alzheimer’s (AD) brain the
tubelen was over 80% on the average abnormal and broken
down and not doing what it was supposed to be doing. The
axions that hold the connections in the proper orientation
had broken down in those brains. We showed them that
mercury and only mercury would cause this breakdown.
Later research showed the living neurons growing and
when they put minus tens which is about 100 times lower
than you would find in an AD brain and you added to the
neurons that were growing, they dissipated. The tubulens
completely separated from the axions and I had seen this
earlier in the chemical measurements.

Since then people in


Korea have researched to show that mercury causes an
increase in Beta amyloid protein. It does this by inhibiting
the enzyme in the brain that is supposed to chew up Beta
amyloid and get rid of it. Their studies show that the
tubulen and axion are inhibited by mercury and this leads to
amyloid plaques. Also hyper-
Posporylation was shown to be induced by treating neuron
cells with mercury. This was done in Switzerland. They
found when you put in mercury the hyper-phosphorylation
of tau which is third diagnostic Hallmark of AD brain
occurred very dramatically.

To make a long story


short we have seen if you look that the abnormal
biochemistry of the tubelen that holds the shape of the
axions and the production of the nerve fibrillary tangles and
hyper-phosphorylation of tau it is the protein that connects
the tubelen to the neuro fibers and gets displaced and does
not get dephospholated in the proper fashion and
phospholation builds up and when you see there are a lot of
other things that happen. There are enzymes in the brain
that are over 90% inhibited in the AD brain and we have
published that.

The only thing that can


cause the inhibition of these proteins is mercury. One is
called creatine kinase which is very common and is found
in every cell in the body. It is looked for in blood tests for
heart attacks to see if the cells have broken open. It is that
important and you have to have high levels of it and all
high energetic ATP utilizing cells. We found that it is
incredibly sensitive to mercury which will inhibit it and an
AD brain is 98% inhibited and if you add a small amount of
mercury or thimerosol that enzyme is dramatically
inhibited. We can absolutely say that mercury has all the
hallmarks, all the biochemistry that it can induce that
leads to the diagnostic hallmarks for AD and the abnormal
biochemistry that you find in an AD brain.

It is almost a shoe-in. If
anything other than mercury everybody would be talking
about it. You cannot get a grant from RNIH to look that
mercury as a cause of AD. They won’t even listen to it
and they won’t fund it. I know because I have tried. The
main reason is that our government has the responsibility
for the highest level of mercury in the body of Americans
based upon the approval of mercury amalgams in dentistry
and flu shots.

Some of our
experiments took a single extracted too with an amalgam
filling and dropped that in one ml of distilled water and
took some of that water and added it to human brain
samples just like we did with adding mercury and we got
the same exact result as we did when we added mercury.
The mercury was coming out of the dental amalgam and
getting in the distilled water. When we added it that water
had the same properties of inhibiting these key enzymes
as the mercury we bought for the tests. The bottom line
is the amount of mercury that we had to the brain samples
to get that level is much less than was found in the brains of
older people that have died and the mercury levels in their
brains were measured.

JONATHAN: on one hand the FDA and dentistry are all


saying mercury fillings won’t hurt anyone. But when
they take them out they treat it like nuclear waste. There is
a massive disconnect. It’s safe when it is being put in and
highly toxic when it is being taken out and be careful where
you put it.

Dr. Haley: I can’t explain these people and if they don’t


wake up and think of what that evil things could be done
today. But I can’t think of a more evil thing than putting an
amalgam filling in the mouth of a person. Mercury is an
element and you cannot break it down and you cannot
change it. It is mercury no matter where it comes from.
We have shown and filmed this. Mercury vapor comes off
fillings and you can see this with a mercury lamp. It looks
like cigarette smoke.

You can put a mercury


vapor analyzer and measure it and show it is mercury and
it’s an element that doesn’t break down. It’s easy to
measure and it’s very toxic. I think I’m being too kind to
these people. They are either incredibly stupid or they are
criminals.
JONATHAN: what about the components of a diseased
brain.
Dr. Haley: we know that the synapses between two neurons
are dramatically reduced in AD and mercury will do that
with in a few seconds of entering the brain. If you breathe
this from a coal fired power plant or any source it doesn’t
make a difference. It is an element that crosses the blood
brain barrier easier than anything I know of. It is oxidized
from HT vapor to HT2+; it goes from it’s non=toxic form
to it’s most toxic form very quickly in the brain and it gets
trapped in the brain and builds up over the years and it
causes the formation and breakdown of the synapses. It
causes the formation of beta-amyloid plaques in the brain.
This is the major diagnostic hallmark.

It was thought this was


the cause of AD and early on in my career I said that they
had no proof it was a cause of the disease. It was a result
of the disease. How you have some thing spontaneously
form in the brain without there being an induction factor? I
had in my grants for 25 years and never missed a funding
cycle and always got excellent scores from the NIH study
sections that reviewed my grants. When I started doing
mercury everything changed and they tried to say the work
I was doing wasn’t well designed. I challenged them on
that and had a different section study it and I won.

The second group said


the things the first group said that made my work not
credible were totally wrong. The next time I went for a
grant they came back and said that Dr. Haley has to
realize that they have seen enough of is type of research
and they actually triaged. They didn’t criticize the grant
and they didn’t say anything was wrong but they said they
didn’t want to see any more of it. That is how I lost my
NIH funding. At that time there was a man, H P Wallace
whose father was vice president under Harry Truman and
he was the person who invented pioneer seed corn. He was
very intelligent and very wealthy. HP was the same way
and he developed laying chickens that laid eggs at a much
higher rate than normal. HP thought that his father died of
mercury toxicity because of sticking his hands in the seed
corn he was planting that had thimerosol on it to keep it
from having fungus grow on it. He then funded me for 5
years and that allowed me to go on with my mercury
research because he wanted to see me accomplish this.

The major damage by


mercury is the neurofibrillary tangles. These are neural
fibers with the tubelen stripped off em. Tubelen does that
and we have shown that with our research. Other people
have shown it in film. When you add mercury to neurons
in culture the tubelen strips of the neural fibers and the
neural fibers start forming a tangle which is the major
diagnostic hallmark of AD. That is another aspect that I
don’t know how the government and the AD Association
look at that and say that is not crucial. How do make every
diagnostic hallmark, pathogenical hallmark about AD with
one specific quality like mercury and not have is in your
mouth in gram quantities and have it be the major
contributor to mercury in your body and say that it is not
a risk factor for AD. You can’t be that stupid.
If you say that mercury
not make somebody who is going to AD get there faster at
the very least if it not causal, you have all the data out there
showing mercury us a neurotoxin and induces the
symptoms of the ‘mad Hatter.’ We know mercury induces
dementia and we don’t look at it and our government does
not fund research to look at the possibility that the metal in
people’s mouths in gram quantities, that this could not be a
major risk factor for AD in these people. You can’t back it
up and say you don’t see it; if you don’t see it, it is because
you are not looking and you don’t want to see it. You
cannot have gram quantities of the most toxic vaporous
metal in your mouth and not have it affect your brain if it
has been there for 20 to 40 years. There is no way.

JONATHAN: dentists are not taking precautions for their


patients, themselves and their staff with mercury.

Dr. Haley: It is incredible to me that they don’t get very


angry that the ADA and the dental branch of the FDA who
try to tell them that this stuff is safe. I know the research
they have looked at and what has been presented to them
by a large number of people, not just me but people of
Sweden and Germany. You cannot ignore this and they do
because of money. The ADA is trying to keep it so the
member dentists can make a lot of money. Forget about
their own health and the health of their patients. The
dentists are the ones most genuinely affected.
I am working now with
a German dentist who has retired after 40 years and he is
incredibly toxic. All the chemical and biochemical
measurements that one can make to see if a person is
mercury toxic with this man show enormous amounts of
mercury in his body and other members of his family don’t
have that. This is from practicing dentistry.

JONATHAN: what are some of the things that he is going


through? Is he suffering physically?
Dr. Haley: He has excessive tremors, inability to sleep,
insomnia, poor digestion and nervousness and he never
relaxes and has a bad temper. He can’t control his temper
and can’t take disagreements. He is forgetful and very
unhealthy. He can’t remember where he is, the names of
certain people and he is very fearful for his general health.

JONATHAN: a lot of people are confused about why he


has neurological damage, memory, tremors, emotional
issues, being easily agitated and quite sensitive to stress.
Mercury is placing such a physical burden on the body. It
keeps the vital nutrients from getting into the body.
Dr. Haley: we know if you have a lot of amalgams you
have a higher blood level of mercury. This goes through
the blood-brain barrier and it has been proven to change
the ability of certain food substances to be transferred
across the blood brain barrier. It inhibits the enzymes and
carriers that prevent the (nutrients from) food from crossing
into the brain and mercury has been to do that. The worst
thing about mercury toxicity is that you are a biochemical
train wreck. Every organ in your body is affected and
primarily in the blood brain barrier is the kidney. You can
clear the kidney appropriately of toxins that are brought
there and you build up and don’t get put into the urine
properly and the pH can go ‘whacko’ because the mercury
affects the acidity and the appropriate basic pH parameters
so there is no end to what mercury does. You are a
biochemical train wreck if you are mercury toxic.

JONATHAN: what other factors are there that cause brain


disease.

Dr. Haley: do you know of anything they talk about that


you might have excess copper, zinc or iron in your brain.
That is the latest theory. You have to understand that there
has to be excess copper, zinc or iron or there would be
oxidative stress to the brain causing inflammation. Copper
comes out of your mitochondria. When mercury gets into
your brain it cannot generate hydroxy radicals. It is not a
redox metal. It displaces the iron and copper that is
appropriately bound in your brain. The mercury goes in
and displaces them and you are building up free iron and
free copper because they have been displaced from their
natural binding sites by mercury and now the free iron and
copper can be used to generative oxidative stress, hydroxy
radicals that cause the breakdown of the brain tissues.
This is a sensible presentation and explanation of how you
get oxidative stress in the brain that you cannot have
without free copper and free iron.

Your body has a firewall of protection against you


absorbing too much copper or iron from your intestines and
getting it into your body and brain. The best way for it to
get there is to be carried there by natural processes and it
gets in the brain. When you breathe mercury vapor, it gets
oxidized and the mercury displaces the redox metals from
their normal bindings. We know this happens because the
iron is primarily displaced is in the mitochondria and the
iron sulphur clusters in the electric transport systems that
are used to make ATP, glutathione and several other things.
We know that this goes down very quickly. The ability to
make ATP in the AD brain is very low and the electric
transport system is dramatically inhibited. This is not
simple, but it’s not unreasonable to think about it.

JONATHAN: a people are skeptical – if this is true why


isn’t everyone out there running around with AD? This is a
balancing game; how much exposure do you have, how
many amalgam fillings do you have, how old are you? Do
you lack anti-oxidants and how is the diet?

Dr. Haley: the most obvious one is the ApoE protein story.
The bottom line is and is proven that ApoE in the brain is a
housekeeping protein and it carries cholesterol and
oxidized lipids out of the brain into the cerebral spinal fluid
and into the blood where it gets cleared by the liver. Now
you have three types of ApoE Protein—ApoE 2, ApoE 3,
and ApoE 4. If you have two copies ApoE 2 you will never
get AD. If you have two copies of ApoE 4 you are
probably going to get AD before you are 60. You have to
explain that. They all do the movement of cholesterol and
oxidized lipids out of the brain adequately. All 3 of them
do that adequately so it has been a conundrum of why
would ApoE 4 put you at risk for AD?

The reason is that in the ApoE 2 protein you have 2 bio


groups on the outside of the protein that combine mercury
and carry it out of the cerebral spinal fluid out of the brain
and have it excreted in the feces of the body through the
liver. When you get to ApoE 4 you have none. These two
carriers are gone and you have very little or no ability to
carry mercury out of the cerebral spinal fluid in the brain.
In between those is ApoE 3 and with that people with
that get AD at a much older age than those with ApoE 4. It
is somewhat protective but not nearly as protective as the
ApoE 2. When you look at genetics the take home lesson
is the type of ApoE protein that can bind the most mercury
and move it out of the brain and the central nervous system
is the one that protects you against AD. The one that can
not do that any longer is the one that puts you at high risk.

In other words the mercury goes into the brain and it


is not carried out. There is no buffering of that mercury so
that is a genetic risk factor and I posed that in 1988. They
will still tell you that ‘they’ don’t know ApoE 4 is a high
risk and ApoE 2 isn’t. The only difference in those two
proteins is that one has 2 cistines and one has 2 arginines.
One can carry out and bind 2 atoms of mercury on the
surface and the other one can bind none. That makes all
the sense in the world and the people in AD research have
totally ignored that because you cannot make a drug for
that.
You cannot make a drug that you can make people take
and monitor for a long, long time. That is the real bad
thing about saying that it is mercury and genetics because
there is no money. The pharmaceutical companies and the
NIH are not going to put money in to research something
that they can’t money on; even it would help Americans
and people all over the world. I talk to a lot of people
especially years back in the Beta amyloid causing the
fibrillary tangles that were the cause and they are not the
cause. They are the result of mercury toxicity. You could
not get these people to stand up and fight against the
administrators in the government and in the pharmaceutical
industry. They want a drug so they can keep someone in
AD and treat them for a long period of time. They don’t
want to come up with something that is going to prevent
AD.

JONATHAN: is there a way to test for this gene?

Dr. Haley: yes, there is a simple blood test for that. You
will have two copies—one from your mom and one from
your dad. So you can 2-2, 2-3, 2-4, 4-2, 4-3, 4-4 and any
combinations of those two. That is what they looked at and
the people that have a copy of ApoE 4 or two copies of
ApoE 4 are very likely to get dementia very early in life.
The worst one to have is the ApoE 4 and the best one to
have is the ApoE 2 and the ApoE 3 is between the two and
is the most common.

JONATHAN: so the mercury in fillings and vaccines


actually cause AD? What kind of science is out there?
Dr. Haley: There are reports from 4 different continents,
from 4 to 5 different countries that show that mercury
induces the formation of the pathological hallmarks of AD.
It does is by a biochemical action by inhibiting and
enzyme, causing a disruption of a biochemical process of
the tubelens and a decrease in the dephosphorylation of tau.
There is a huge amount of medical research showing that
mercury causes many of the abnormal biochemical aspects
that we see in AD. I would have a hard time telling you all
of them. They are published and they are listed in the
papers. They are there and they are widely ignored by the
neurological societies and yet they won’t even invite me to
a debate. Why don’t they take me in and beat me up if I am
so wrong? I’d never turn them down about talking. It
makes too much sense. But there are too many people that
will lose too much money if all of a sudden we say the
cause of this is mercury exposure.

JONATHAN: a lot of people have these amalgam fillings.


If people remove them they need to be very careful to not
rush and have them taken out. Dr. Leonard Fazio details
what a dentist does to protect you, his staff and himself.
What is your advice for detoxing safely?

Dr. Haley: there is a documentary that was done called You


Put What in My Mouth? In that documentary movie some
dentists are being very careful about taking amalgam out.
They show a drill where they put it on the amalgam filling
in a cadaver or plastic skeleton head with teeth. When they
do that the whole room goes black because of the mercury
vapor that is kicked out. That should convince anyone and
they measured it and showed the mercury levels went up in
the room, way above what would be considered safe for a
human to breathe.

I would say if you go to a dentist and he say she is


using amalgam go to another dentist because he is not that
all concerned about your health and exposure and his
exposure. Go to a dentist that will not place an amalgam
filling and works hard at protecting himself from mercury
vapor. If he is protecting himself he is protecting you. I’d
be very careful about running out and having your
amalgams replaced by just anybody or have a bunch of
them done at once.

There are a lot of problems going on and I would say we


really need to make sure your body is healthy enough. Get
some of the chelators that are available and there are none
of them right now that work all that well. We hope to have
a new one out soon and it will have a 22 r half life in your
blood that will prevent you from mercury exposure. Go to
someone who is not placing amalgam fillings. If they are
placing them they do not care.

There are a lot of dietary aspects and you want to make


sure your body is getting adequate amounts of cistine that
is the enzyme that blocks and binds mercury. Also there is
lipoic acid which is a key component in your body that
allows you to go from glycolosis to the citric acid cycle.
Lipoic acid has a very high affinity for mercury and that is
a good thing for treatment to bind the mercury to get rid of
it. But it is bad from the standpoint the enzyme parvad-
hydrogenase (?) which is dramatically inhibited by mercury
because of the high affinity of mercury for the lipoic acid
which is the co-factor for the enzyme. The biochemistry
here is very complex. I know a lot of people may wonder
what I am talking about. It is solid science but it is not
simple. The lipoic acid is alphalipoic acid.

Vitamin C is some thing that dentists use and those who


treat heavy metal toxicity give high doses IV. It does not
bind the mercury but it increases the level of glutathione
and vitamin C will increase the level of glutathione in your
cells by a biochemical pathway. Glutathione is the major
component in your body that binds mercury and takes it out
of the body safely. Do anything you can to reduce
oxidative stress and increase glutathione.

Be cautious because you cannot take glutathione IV and


have it go in your cells. It has a one way transport out of
cells. Vitamin C does not go into cells that well at all. You
can take the Vitamin C IV and it will get into the cells and
cause oxidized glutathione to go back to reduced
glutathione which has a high affinity for mercury, removes
it and detoxifies the body.

Dehydration is dangerous with or without mercury. The


mercury is enhanced by dehydration as the concentration of
mercury is at a higher level when you are dehydrated. It is a
key element that people have to work on. I am not an
expert on hydration. But it is important when removing
toxins through the fecal material or the urine. Selenium
binds mercury very tightly and renders the mercury non-
toxic. People who worked in mercury mines had diets high
in selenium and they would have very high levels of
mercury in their brains and not be demented yet. For every
atom of mercury they had an atom of selenium which is
very good at decreasing the toxic effect of mercury. If I
were going to have an amalgam filling taken out I would
take the maximum amount of selenium that can be taken
safely. You have to be very careful with that because the
downside of selenium is that it is quite toxic. You cannot
take a huge amount but it does bind up mercury and render
it non-reactive.

I based a new chelator that I am getting through the


FDA and EMA right now for a chelator of mercury. It
binds mercury so tightly that it never lets go and it renders
the mercury non-toxic while it is in place. That is what
selenium does. It will prevent mercury inside the cells from
being toxic and will never let it go.

JONATHAN: some dentists are rinsing mouths with


charcoals and swallowing plus things like cholorella.

Dr. Haley: that is not as silly as it might seem. In our


studies when we are doing the mercury vapors and
exposing rats to the vapor, when the air leaves the sealed
cage it goes through a charcoal filter that binds most of
the mercury vapor and renders it non toxic and keeps it
from going out in the environment. Also, Dr. Chris Shade
has a compound you can eat. It doesn’t go outside the gut
but it has a very high affinity for mercury and it keeps chips
you might swallow during a dental procedure and this
absorbs that mercury and decreases the amount of mercury
that is in your body. He has a very sensible approach.

JONATHAN: would you review the amount of mercury


that is in one filling?

Dr. Haley: the acceptable rate of mercury in your body is


1/10mg per 2.5lbs per day. If you look at an amalgam
filling in a jaw tooth it can be from 1 to 4 grams. Some are
bigger and some are smaller. 1 gram is 1000mg or
600,000mcg. We consider 10 mcg a day as huge exposure.
I don’t know how they allow this in someone’s mouth. In
my opinion it is criminal with what we have seen and what
we know about the toxins in mercury and how it builds up
in people. We are getting a huge amount of mercury in the
environment coming over on the Manchurian Plume as they
call it from China, India, Indonesia and Japan who are
burning dirty coal. Now the mercury level in the western
US have gone up even in the western mountains where
there are not dental treatment facilities. We are slowly
building up the mercury level in our bodies to the point that
people are going to get seriously ill because mercury is all
added from the coal fired plants in China and in the US and
from vaccines, dental amalgams and everything else that is
building up. And we are eating the fish that are adding to
it; we have a major problem.

JONATHAN: what about aluminum and the synergistic


effect?
Dr. Haley: I have done studies that had neurons in cultures
that will live for 24 hours with less than 5% dying. We
added thimerosol from the vaccines and it would kill them
over a 24 hour period. We could measure the effect of
additive things. We found that aluminum, zinc, copper and
lead had a synergistic effect on the mercury and with
mercury it is 100 times more toxic in your body than if you
have a non-toxic level in your body. This was published by
a researcher many years ago and we confirmed it. If you are
taking antibiotics that causes your body to keep more
mercury and it will dramatically increase the toxicity. The
neurons and culture that we created with the thimerosol and
when we added aluminum that is in vaccines, it increased
the toxicity ten-fold. The male hormones were synergistic
about making mercury toxic. In my opinion this is one of
the reasons why you have boys with so many neurological
diseases in excess of what the female population has. There
is 1 out 5 autistic children who are females. When we add
the female hormone to the thimerosol it had the opposite
effect and enhanced the effect of the toxicity.

JONATHAN: so testosterone puts you at a greater risk for


mercury exposure?

Dr. Haley: absolutely and this was researched by a person


who does not want to talk about it, Dr. Baron Cohen in
London. He analyzed the amniotic fluid of mothers that
gave birth to autistic children and appropriate controls.
The only thing they found that was different was that the
Mothers who gave birth to the autistic children had very
high levels of testosterone in their amniotic fluid. Those
babies when incubating and growing were being exposed to
higher levels of testosterone and when the mercury came in
it was more effective on them than on the children who
were in the amniotic fluid with less testosterone.

JONATHAN: the female might be the stronger of two


sexes and are protected by their hormones.

***********
Chris Shade PhD: environmental chemistry, mercury
analysis, founded Quicksilver Scientific, mercury and detox

JONATHAN: how should testing be done?

DR. SHADE: there are different forms of mercury; you


have methylmercuy from fish and inorganic mercury from
amalgam fillings. There is also ehtylmercury from
vaccines. And for now we will focus on the fish-based
form and inorganic. They have always been lumped
together and measured I urine, hair, blood or stool. The
problem we faced was that those forms lumped together
each thing you could measure was showing you something
totally different. Hair was all ethyl mercury which all from
fish. If the mercury is high it means that you eat a lot of
fish. If you don’t eat fish and have a lot of amalgam the
mercury in the hair is low.

Urinary mercury was all inorganic and if you have a lot


of amalgam the urine should be high but only if the kidneys
are functioning properly. If you have damage to the
transporter in the proximal tubules you will get low
mercury in the urine which could be good or bad. It’s
either low load or it is supporting detoxification. Blood
was dominated by methylmercury and was more of the
reflection of how much fish you ate. Any one alone was
very useful.

In mercury speciation testing we separate the methyl


mercury and inorganic mercury in the blood so we can see
them individually. In the blood the inorganic mercury load
is hiding behind the methylmercury load. When you
separate them blood is a good indicator of body mercury.
For a long time people didn’t’ like blood because it wasn’t
reflecting the inorganic very well until we did the
speciation testing. That has a bit of limitation to it because
we want to know if it high in blood because your load is
high or because you are not excreting, which is called
retention toxicity. In fact historical Hal Huggins in the early
70s started talking about retention toxicity. He was able to
measure urine and he saw if you saw two people with a
mouthful of amalgam and one had low mercury in the urine
and one had high mercury in the urine, it was the person
with the low mercury in the urine that was the sickest.

He couldn’t compare that to speciated mercury in the


blood and see that there was retention. He estimated that
there was retention. Now we can look at urinary inorganic
output and compare it to blood inorganic output and get a
clean indication in how well the kidneys are excreting that
form of mercury. People with low excretion in the urine
have some sort of damage in the transport system in the
kidneys. This is either from chronic infection or a past
damage done to the kidneys.
In the literature the best way that damage was created
was a combination of endotoxins which are parts of gram
negative bacteria and it is common to get that from leaky
gut, chronic infections from root canals and cavitations and
chronic sinus infections or chronic UTI. Those in
combination with the metal load were shown to disrupt the
transport system in the kidneys and giving you lower
urinary mercury but higher body mercury. So now the
testing we do we can compare blood mercury to urine
mercury and also to hair. We can see what levels you have
as a body burden from the body levels but also how well
your excretion is working from your urine and also from
your hair.

I said hair was the measure of methylmercury that


should be proportionate to your blood. But some people
have a disruption in the movement of the methylmercury
from the blood into the hair and they end up with low hair
mercury but high blood methylmercury. That is more an
indicator of how well your sulphur system and your liver
are able to move methyl mercury. This way that we
measure these traces to research by Boyd Haley, Amy
Homes and Mark Flacks about 2 decades ago.

They found that given the load from the mother the
children with autism had very low loads in the hair. The
severity of autism was inversely proportional to the amount
of mercury in the hair. That disruption of transport in the
hair is the indication of the transport predominately in the
methylmercury levels. We have speciated blood mercury
compared to inorganic mercury in the urine and
methylmercury (hair). That is the Quicksilver Mercury Tri-
Test. It has become some a popular test that Mark
Hyman’s group in Massachusetts and the Functional
Medicine doctors. They are adding this testing to
Cleveland Clinic which is bringing mercury toxicity into
the national spotlight.

J; you mentioned stool. Is there value in testing the stool?


Also tell us that the significance of what you have
described is understanding what is functionally happening
in the body and you are going to detox this out of the body.

DR. SHADE: this is your road map you have different


forms of mercury going in different ways and excreting in
different ways the tri-test give you that. Inorganic mercury
is the pool in the blood I look for the biggest indicator of
toxicity. People make inorganic mercury from the
methylmercury even if they don’t have amalgams. The do it
at different rates. Some people eat a lot of fish and some
people will turn that methylmercury into inorganic
mercury, the more toxic form. And other person will not
turn much into inorganic mercury. We can tell fish eaters
their bio-risk in how they transform the mercury.

The detox pathway of urine and hair tell us how we


will approach the detoxification. If you have high blood
inorganic mercury and low urine inorganic mercury the
retention toxicity is pointed to by Hal Huggins. We know
we have to work on your kidneys first before we try to
mobilize mercury from the rest of your body. This is our
roadmap and what defines how we will approach this.
We don’t do stools because there is a lot of
biotransformation that happens in the GI tract. People don’t
like to do stool testing unless they are really sick. If they
are borderline sick or doing preventive there is low
compliance. When people’s bodies are locked up and they
are not moving mercury out of their system when we test
these people they will have very low levels in the blood, the
hair and the urine. We know that we have to work on
methylation pathways that involve methylfolate, B12,
methyl glycine, activated B vitamins and you will look for
the stool levels to increase. When they do we know we
have reached the blockage. That is how I like to use stool
tests.

JONATHAN: what are the limitations of chelation


challenge testing?

DR. SHADE: I have a paper on the website where I look at


5 journal articles that examined chelation challenge testing
and showed it didn’t bring good information to light.
Ambient testing is how we do our testing. Chelation
challenge testing had a great role 20 to 30 years ago when
we didn’t have good sensitive testing looking at the low
levels coming out of your body. Most people urine levels
were low detection and they couldn’t detect below certain
levels. If we gave chelators the levels came out and that
amplified the levels that were already coming out of the
urine.
It became easier to see who was low and high now
with our testing. Challenge testing was only amplifying the
signal that was there. It was only urine and it relied on the
same proteins that are required for ambient urine it was
susceptible to false negative. If you had kidney damage we
could challenge you, you would show low and we
mobilized urine in the blood, pushed it towards the kidneys
and it didn’t come out. So the first problem was false
negatives and secondly the challenge in already toxic
systems with the redirection of the mercury in the body
through the challenges.

The people who needed it the most sick and this


challenge often made them worse. Now that we have a very
sophisticated testing we can do the testing without
challenging. There is no reason to challenge. There is a lot
of mythology around the challenging. We have to focus
more on ambient measurements. The challenge was good
for challenging for lead that was more indicative of bone
lead than blood lead.

JONATHAN: you taught not to rush to detoxify. Moving


things and not eliminating will cause some serious
symptoms.
DR. SHADE: I did that myself using DMSA with poorly
functioning kidneys. I didn’t know all this and I got myself
really sick and I had to restore the natural glutathione
system to get better.

Mercury detoxification came from overdoing the


DMSA and it wasn’t showing in the urine and I got sicker
and I was exhausted and run down, brain fog and chronic
fatigue. I realized I shouldn’t force mercury through my
kidneys but coax it out through the GI tract. The
glutathione works to effect natural mercury detoxification.
You need intracellular glutathione at adequate levels. You
also need a linking protein called a transferase. It is called
glutathione S-transferase and this means that it is catalyzing
a movement of the metal (mercury) form the cellular
proteins where it is bound onto the glutathione. The
transferase catalyzes removing the metal from the protein
onto the glutathione. So now we are inside the cell and a
mercury glutathione conjugate and we need to get it out of
the cell and out of the body. These are microcosm and
macrocosm and I explain detoxification is there is cellular
detoxification involving the glutathione system and there is
movement from the cell to the circulated fluids of blood
and lymph. Then there is the filtration of those.

We made a glutathione mercury conjugate that is in


the cell and we need to get it out. There is a transporter, a
transmembrane transporter in the biomembrane of the cell
and it is called the multi-drug resistance protein and it uses
magnesium, ATP to push that mercury glutathione
conjugate from the inside of the cell to the outside of the
cell. It goes in the blood in the circulation and there are
other transport proteins that are called phase 3 transport
proteins that pull that mercury glutathione conjugate from
the blood into the liver, from the liver to the bio-tract and
the small intestine. The same transport proteins are in the
proximate tubules that pull it from the blood and push it
into the urinary stream. And you have the transport
proteins in the upper areas of the small intestines. The
kidneys, liver and GI filter the blood and push that out as
excretion in the feces and urine. 22.46

JONATHAN: is feeling horrible when detoxifying a good


thing? I want to issue a warning for people with serious
health issues and heart arythmias to be careful.

DR. SHADE: absolutely cored; you should feel a certain


amount of symptoms, mainly feeling more tired.
Remember I said those transporters are using ATP (cellular
energy) and you are mobilizing energy forces toward
detoxification and that should make you a little tired. You
may have some GI distress, gassiness and lose stools. That
should be about all there is. If you really feel crappy then
you have really strong free radical damage happening and
you are pushing things to fast.

I was trying to forth the issue with DSEA and I had a


vision of my cell membranes exploding as I moved as I
moved all this stuff. It was really radical stuff I was going
through and they were really damaging. Some of us have
done some long term damage while we were trying to
figure this out. A lot of the kidney damage comes from
pushing to too hard and it is very, very hard to reverse. A
lot of the nerve issues that go on are not so much the
central nervous system but the autonomic system damage.
The autonomics are moving through the extra cellular
matrix and that has to handle the movement of a lot of
toxins at this point. It is very easy to damage the
autonomic nerves and they are the ones controlling your
metabolism.

They are controlling your heart rate, your metabolism,


your respiration rate, your sympathetic versus
parasympathetic, digestion and blood flow to every one of
your organs. When you poison them you can end up with
strange, non-linear organ stresses. It is not clear how you
got into this problem if you move through your detox at a
steady rate, start low with the compounds you are using and
work up with a high level over months and not days.

The other thing you need to do is pulse—time on and


time off. You can do that within a week, you can do 4 or 5
days on and 2 or 3 days off. Or do this over a period of 2
weeks. The most amount of time on I like to see is 10 days
and then 4 days off. This is the ideal but you might want to
start with 4 to 5 days on and 2 to 3 days off. You need to
give your body breaks in between. Then every 3 months
you want to do a month off before you go into another
round of this. This is the safe way to get solid detox
without going sideways.

JONATHAN: what can you use for mercury detox?

DR. SHADE: we have three requirements of glutathione,


glutathione transferring and the transport protein. These
are framed as phases of detoxification: phase 1 is not part
of metal detox; phase 2 is toxin plus glutathione; phase 3 is
transport protein. Phase 2 is the conjugation of bringing
the toxin and the glutathione together and Phase are the
transporters. When we design a program we need to
address all 3 things, the glutathione, the transfer agent and
the transport.

Let’s start from the transport as this brings us to a


fundamental part of all health and that is the GI tract. The
transport chain, the blood, the liver and the GI is controlled
by the help of the transport into the GI tract. When you
have inflammation in the GI tract or a build up of toxins in
the GI tract you cannot and often that will be the same
thing you cannot stop the transport chain.

Whenever you are moving a toxin down to the GI tract


you need to be collecting that toxin and moving it out.
Sweep away so that the transport chain can keep moving
the toxins down the GI tract. As my friend Steve Hines
said about our product IMV it is specific for moving
mercury and other heavy metals out of the GI tract. As
they move out of the way the body signals that glutathione
to move more mercury down there. These products are
sweeping metal and other metals out of the GI tract are
generically termed ‘binders.’ Often people talk about
mobilizers that move mercury into circulation and binders
that will grab them from the GI tract and take them out.

There are various binders people use and each of them


has its “chemical sweet spot.” For metals we make a
product called IMD (intestinal metal detox) and it is a
silicone dioxide particle with sulfhydro groups. The
sulfydro groups are the same kind of sulphur that
covalently binds mercury, cadmium, arsenic, lead and the
same kind of sulphur that is on glutathione and DMSA.
These are bound on to that particle so the particle moves
through the GI tract and collects all those metals, holds on
to them and sweeps them away to excretion. The natural
form that is used by a lot of naturopaths is chlorella. On
chlorella membrane there are some sulfhydro groups. They
have a strong bonding for mercury and other metals but
there are not a lot of sulfhydro groups. For instance our 6
gram bottle of vitamin D is equivalent to about 3000
chlorella. To get the effect we get with 100mg of IMD you
need between 70 and 90 chlorella and that is a lot of
chlorella. When you get to that level it stimulates
symptoms in you.

JONATHAN: I was playing around with chlorella and


liquid cilantro and the neurological symptoms for my brain
and legs were crazy.
DR. SHADE: the cilantro is the one that is the mobilzer
but I have never incorporated it into my system because
there is no scientific data on what pathways it affects or the
molecules in there. It is anecdotal and it does do something
but there tend to be a lot of people getting neurological
issues from that. There is mobilization that may go into the
brain as much as it comes out of the brain and there is a lot
of reporting of neurological symptoms when people use the
liquid cilantro.

JONATHAN: I have no idea what is behind it, but there


was a liquid live blue green type algae and it was ‘in my
head’ and deep within my brain with my sinuses opening
up. I thought that was a good thing but that was happening
constantly for hours and it was very unsettling.

DR. SHADE: I think I know what you are talking about


and they bring the cell membranes down to the tiny pieces
that get into circulation and they move into the brain. I am
not sure that those should be in circulation because you can
have a strong immune response to those and have strange
symptoms. If you have a bad immune response that will
lead to more inflammation. One of the most important
things to realize is that inflammation blocks detoxification.
What happens when you make detoxification happen too
quickly, it stimulates inflammation that then locks the
system up?

As we are trying to trying to coax the system into


working and effectively moving these glutathione
conjugates down and out of the body if we move the
system too fast it locks the system up. As we move back to
our detox story, we need to clear away toxins in the GI tract
with the binders. I mentioned the silica based IMD that we
used, chlorella, and there are other binders that are good to
bring in. they are not specific for metals and that is
bentonite clay, zeolite and charcoal. Those are good to add
in but you do need a mercury specific one like our IMD or
high doses of chlorella.

We have covered the gut moving the metals out of the


gut that opens the transport chain. Now we want to
stimulate the phase 2 enzymes and the glutathione synthesis
in the body to get the cells to push the mercury out. The
way we regulate the intra cellular processes is through
activation of a gene switch called Nrf2 is a protein that is
outside of the nucleus that gets stimulated to be transported
into the nucleus and when it does this all the genes that are
responsible for chemo protection which is another word for
detoxification, the chemo protection genes are all
stimulated to be transcribed and the protein they code for
are built.

So there is up-regulation of the synthesis of those


phase 2 enzymes for glutathione transferring. What
compounds stimulate these? The most potent we use is
lipoic acid and more specific than that the r-lipoic acid
which is very strong, easy to standardize and reliable.
Another up-regulating compounds are polyphenolic
antioxidants such as green tea extract, pomegranate extract,
pine bark extract and a lot of lot of the ayurvedic
polyphenols that you would you would find in a mix like
Triphala and the one we use most is called ‘harataki’ and
there are others that also do that such amylaki and bibytaki.

Polyphenols do not have very good absorption so you


need to take 100 to 1000 mg orally to get this kind of up-
regulation. With the lipoic acid you are talking about tens
of milligrams. Other compounds that do this in the sulphur
chemicals are the compounds present in the crucifers such
as broccoli. The strongest one is sulfurothane which comes
from broccoli seed extract. Wasabi also has a powerful
compound called aloisothyonate and wasabi works in this
fashion. There are a number of compounds that are present
in cabbage, and red cabbage is stronger than green cabbage.
Fermented crucifers will heal the gut as well as brining the
Nrf2 regulators and then you have the sulphur compounds
also present in garlic.

It is important to note that it is not the anti-microbial


compound but dialosulfides that is the odorous component
of garlic that does that. You can get garlic oil capsules and
those are the ones that one. If you get de-odorized garlic it
does not work at all for Nrf2 upregulaton.

The most fascinating thing about the Nrf2


upregulation is that lipoic acid and the polyphenols are
what people think of as being the anti-oxidants. But they
are not anti-oxidants in how they work in the upregulation.
In fact they generate free radicals which stimulate the Nrf2
regulation because the Nrf2 regulation is coded in the genes
to mop up the free radicals. These are actually are pro-
oxidants. This brings us to other compounds that upregulate
Nrf2 which are pro-oxidants such as ozone therapy—oral,
rectal and IV. Some of the new pro-oxidant things on the
market upregulate Nrf2 such as ‘athea’ (?).

So, it is often not exactly what we think when we take


these things that we think are anti-oxidants. They are only
anti-oxidants once they upregulate the anti-oxidant
chemistry inside the body the last player is glutathione. We
can upregulate glutathione production in the cell by turning
up Nrf2 activation and coupling that to feeding precursors
such as _____, ______ or rafe (?) powder but for some
people it is such stress to the system they cannot effectively
upregulate enough glutathione and in that case we bring in
glutathione directly in the form of a liposomal glutathione.
We make the premium liposomal glutathione in our
Quicksilver Delivery glutathione where our liposomes are
small enough to be absorbed through the oral cavity and
bring in reduced glutathione directly into circulation.

Someone did independent testing of all the


glutathiones that are on the market because they were
interested in using ours. Most of the liposomal glutathiones
on the market are already oxidized, not in the reduced form
and will not be effective for using as a glutathione
supplement.

That covers the three main things – the GI tract


cleanup for keeping the transport proteins going and the
Nrf2 upregulation via the lipoic acid, the polyphenols or the
food based sulphur chemicals and then the bringing up the
glutathione levels. If you do all of those and you gently
bring up the doses of everything you will get a very
effective detoxification.

JONATHAN: the future of medicine is right now. I


strongly encourage you to reach out to Dr. Shade and
understand the three pathways of detoxification. This is
helping the system along and not doing things in one or two
weeks. It is so clear why people are suffering from
mercury toxicity issues and heavy metals in general. What
I am referring to is the farming system, our agricultural
system that is de-mineralizing the soil; there is lower
mineral content in our food supply, talk about fermented
beets and beet juices that are fantastic in the body. Anti
oxidant levels are low also because of the food quality.
People have toxicity from heavy metals that is affecting
their brain and their heart, liver, kidneys, GI tract, and the
inability to absorb nutrients in the foods they eat.

DR. SHADE: this is picture that is missing the final picture


that answers the questions for so many practitioners about
exactly how certain people get so sick and then are really
hard to fix. How does the whole system get blocked and
what stops people from starting to detoxify? The most
common answer is that there are mold toxins. We are in an
era where we have hyper insulated houses and closed off all
circulation and in doing that we have created a lot of mold
problems in buildings.

The most fundamentally shattering research I have


found in the last year; mold toxins epigenetically block
Nrf2 switch. That switch is your stress response to when
you get toxic and the foods that should activate it. It should
be able to activate on its own, and you should be able to
clear some of these toxins. But the mold toxin
fundamentally blocks and when that happens something
very interesting happens and when you see it, it makes so
much sense. Those same compounds that we wanted to
give you to upregulate your detoxification pathways,
instead of lightly stimulating detoxification become toxins
themselves. Remember I said they generate free radicals
and that stimulates your detoxification system to
upregulate?
Now that switch is broken and they just generate free
radicals and now you give them lipoic acid and they get
worse; you give them some of the polyphenols and they
have high reactions to it. These people take a long, long
time to get better. So you them on a caps (?) diet and
fermented foods if they can tolerate any sulphur
compounds from the crucifers. Often they cannot. So this
is why so many people that are really sick have both mold
toxicity and mercury toxicity because the molds have shut
off all the detox system. These are the people who are
precisely the sickest.

JONATHAN: so how do we remove these blockages?

DR. SHADE: I am so glad I have an answer; otherwise I


would feel lousy. It is diindolylmethane. We have found
research on that being able to reverse the epigenetic block
on the Nrf2 and we made a lipid nano particle
diindolylmethane that we have had stunning results
reversing all the hardest cases. They couldn’t take
glutathione or lipoic acid. After a few days on
diindolylmethane all of a sudden they are able to take all
that stuff that made them worse and they come out of the
darkness. And they are able to do a successful
detoxification again. It is really the most exciting thing that
I have found in this nutritional chemistry since I started the
company.

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