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'The Gastrointestinal System al a Glance The Gastrointestinal System ata Glance SATISH KESHAV MBBCh (Wits), DPhil (Oxon), MRCP(UK) Consultant Gastroenterologist Director, Centre for Gastroenterology ty College Medical School London Blackwell Science THEUNIVERSITY OF QUEENSLAND LIBRARY 72 38 SUSY PAH (© 2004by Blackwell Science Lid ABlucksell Publishing company Blackel Sssnce, li, 350 Mii tre, Malden, Massachsets 02148-5020, USA. Backvell Pobishng Lu, 9400 Garsington Road, Oxford OX42DQ, UK ‘BuackwellSience Asa PyLi, 550 Swans Stet, Carion, Vitoria 3083, Ausra “Thesight ofthe Author tokens the Astorof this Worchas been assem accordance with the Copyright, Designs and Pateas Act 1988, Alig tesersed No prt hs pblaion ay he roped oredinarerieval sytem, ‘ortanste, in any oem by any means, clectonic, mechanical, photocopying recording or ‘there except permit the UK Copyright, Designs and Pens Act 88, without the priorpernision fo publish. cs pie 008 Library of Congress Catalouing-ia-Puicaton Data Keshav Sah The gastrointestinal systema plarce/Sas Rosh, — sted ee Tnctes index ISBNO.632.083729 1, Gaseoinesinal ystem, 2 Gistroinesinal tem —Discaes IDNLM: 1, DigesiveSystem, 2. Digestive System Diseoses. W110 Kang 2003)1. Te OP I35.K447 2008 s1292-uerl 2005001042 san oan2.0ss72.7 cule record for this tie save com the Bish Library Setin 9/115 Testy SNP Bes set Typeserer Ld. Hong Kong Prine anhou inthe United Kingdon hy Ashford Cou Press, Gosport Commissioning dor: FonaGoodgame ‘Mataging Eto Gera ees Prato Ft: Fina Patisom Production Conzller Kate Chirman Forturiernformaionon Blackwell Publishing stout website psfowhlckvepuising corn Contents 15 16 0 Is 19 20 a 2 2B Preface 7 ‘Acknowledgements § Listotabbreviations 9 Intraductionand overview 10 Part Structure and function Mouthandtceth 12 Salivary glands M4 Tongueand pharynx. 16 esophagus 18 Stomach 20 Duodenum 22 Pancreas. 24 Liver 26 Biliary system 28 Hepatic portal system 30 Jejunum andileum 32 Caecumand sppendix 34 Colon 36 Rectumand anus 38 Part2 Integrated function Enterie motility 40 Enteric endocrine system 42 Bnterieand autonomic nerves 44 Mucosal immune system 46 Digestion and absorption 48 Digestion of carbohydrates, proteinsand fats 0 Digestion of vitamins and minerals 52 Nutrition 54 Fluid and electrolyte balance 56 Zeno Tue Woe Prov ey 25 43 45 46 47 48 Hepatic metahotic and synthetic function $8 Hepatic detoxification and excretion 60 Part3 Disorders and diseases Nausea and vomiting 62 Dizethoea 64 Constipation 66 Fonctional disorders and iritable bowel sy Gastro-oesophageal reflux and hiatus hernia 70 Peptic ulcerand Helicobacter pylori 72 Gastroenteritis and food poisoning. 74 Gastrointestinal system infections 76 Ulcerative colitis and Crohn's disease 78 Coeliae disease 80 Obesity and malnutrition $2 Colonand rectal cancer 84 Gastrointestinal, pancreatic and liver tumours 86 Haemorhoidsandanorectal disease $8 Gallstones and pancreatitis 90 Hepatitis and acute liver disease 92 Cihosis andchronic liverdisease 94 rome 68 Part4 Diagnosis and treatment Clinical assessment and blood tests 96 ndoscopy 98 Radiology and imaging 100, Functional tests. 102 Pharmacotherapy 104 Gastrointestinal surgery 106 Index 109) | A i, Do iT NOW Preface How to use this book ‘Thisbook presensa graphic scaffold or further detiledstady’and isan ad to revision, Therefore it will be useful for sulents approaching a subject For the fist ime, particularly as part of an integrated systems based medical curriculum. The diagrams will make abstract concepts ‘more memorable and help the stent o recall details that might ber- vise be ost in plaintext. The suelent may further annotate the digas With additional details from letuees, tutorials and self-directed stay, hp wit aterrevision Organization of the book “The books organize four pat, starting with structural ad ne sional overview of the main component ofthe pastrointesil system, followed by consideration of iterated gastrointestinal function, ‘hich sequites some preveding sie knowledge, Clinica examples are inlude toughout these erly chapters highlighting the practical importance ofeach subject ‘The third and fourth sections are more clinical, and cover the most Important gastrointestinal and) hepatobiliary diseases and the main aspects of diagnosis and tretment. Fundamental pathophysioogical mechanismsare emphasized, ‘Anatomical and clinical detait ‘The anatomical diagrams are functional representations, and not exaet reproductions, and they are used (oilustate how stucture supports function ‘Similarly, specific diseases are discuss! to demonstrate pathogenic mechanisms and general principles rather than to provide exhaustive ‘detail, This book should be used to understand the normal physiology, hhow it goes wrong in disease, and the principles underlying modern

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