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PAPUIl : !1.[SUdR(]]r METTI$l]OL0{;y

r. Introduc'ruD & lk& arch lc6ig!

liatLrrr: and oirjcctivcs r:f rcsear*h. \,[ethods of Researei.:: hisrcricsl. derr.r,rpl,i'e ]n,
r:\lcxrmc;:lul, r(Jeirr.rli p!o{c!s. :.cse*r.rlt approac}rea, rrit{ria lol good fcac{rcl.
i.!:r:ni;rg oI rlixjs!'rh ..1!$;6n, rerd cl xs*arc-\ .lesign, l'eraulx). oi gorxl rltsign. {iiii.cr.enl
rcioar.iJ d{rsign!r. pnd Lgsic pri.eip)e* {lfrrperirnertal desiga$. deaigr aifenpe*rii$rk.
Z ,)8t,, cc!ll.rli.,n & Aaolysu;
'l'rrils of.jttdt- [retinals er.l xcl.:niquer of data collcciion, plifiiit], ntd Aecoil.ler_r
ialn. i.jati,
iirl&iy$is. ht$!oai.rl $rcih{ds, caratllt sn&l}sis, dcvicrs llsed ilr dittn {ollealron.
1:tlot aluriy n6ri
rr*aetsi of (}0lti, ..ioica oi dau coil.ction r}1eLLode.
3. l,ro*esring and aoslysis *ldxr*
l!l!iiir,r.:i oI {_-'erl-r;rl 'i!l)i-li:nr:-;,. }1ci:ar.1] r:r ol
}:'glrsion. }Iessilrte rl yal.r*tior). lltasnrtli r)f
( l;l|al 'l'cnJencv vs. .',{eavurrs 0a Djr"pefsrrn, Nrnnar di*tvibntsn, !rca*rrrex oI skewnrss
*n.i !;lirrrlrclario*, corrriatlln and Rep rseiln ilipes & apl:lirarinn,. ahr-irqurir irsr: rr.t
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4. P*pcr nritirg and r.port g.ierstirln

lirlric fi,t.$t. ol'Pnper I tbesi'r x,riting aod !.port gelerstio.r, $riiirE ll.&x&r.h A!3rr;rcr,
i llt)duction. .criclr oi litt,]?tur.e. Ilqvult, Conr!wion. C$sce!t$ of Bibiiegraphy, ancl
lli:tl.rr r;r:ts. ;igrriia,rnce of rr:ion raiiting. si$!s of ,,port wri{ing, ?y}r$ ,i Tles(,rr(l
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i. (bmpulcrApplictr{iors
,ippur:llioi1 oI qtintfllirr ra rcrear{h. Cararatrng cha*&t grrph rn i*ic|rsoli
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priJrr prcs4hrrii.)r'r .wab search: iDtrorju$:on r.l, l4rer'$ri.,
u$e at rnLrno! i!ww. r-asrn!
rcarch sntirr lilo Crrogir:. Yaireio er: ^r)i,

Hcicrence iloo;t$: lat et tidltiors rtfo:lo\&i,ig Bo$k$

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ii. ,j<rhn \\' (tlls*ril. llc;rarci: i}'lst;1r. $rlCI pu!lications, lNf.l.
iri. 'i':.rvi.Ji llt ri Shuitll i,t.i).; jlcsr:rrrh iiierhoijoiogy, f.{)}lege bo$k
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by x-ray diftiaction. Conccpl ol arnorphor-rs, single and polycrystallinc struclurcs
and their e{fcct on propcrtics oi'rnatelials. Cry''stal grorvth tcchniclucs.

Ilolymers: (llassiiication. polr,rrcrization, structuro and prol.rertics. rrldirivcs lbr

polyrncr products. prr:ccssinu and tltplications.

Conrpositcs: Propcrtics anil appl iciuions olvzLrious conrpositcs.

chemistry of metal *chelate Equilibria: Types of complex equilibria in solution,
Equilibrium constant, Fquil .ibri um constant involving concentration and activities'
The complex fonnation function. Methods for calculation of comple* stability
constant, Effect of extemal factors on the stability constants, Relationship between
ihe properties of central metal ions and the stability coffitants, Correlation between

the properties of a ligand and the stability of its metal complexes. Role of metal
ions and complexes in various biochemical processes, Use of cheiating agents.

Important Terminology in Medicinal Chemistry, Routes of drug administration'

Adverse effects of dmgs. Concept of SAR and QSAR' Relation between chemical

structure and biological activity. Difference between Hansch analysis and Free &
Wilson analysis. Enzyme inhihition, Bioirans fomation Xenobiotics.

Classification Chetristry and mode of action of following drugs:-

a) Sulpha drugs:- Sulphanilamide, Sulphadiazine, Sulphaacetamide and

Sulphaguinidile
b) p- laclam antibiotics:- penicillin-G, Amoxicillin and Ampicillin Cloxacillin

p) Antipyretic and analysis:- Paracetamol, aspirin and Ibuprofen

iProfessor & Head

K:I:olf.-*