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available at www.sciencedirect.com
journal homepage: www.europeanurology.com/eufocus

Review – Andrology

Orchidopexy for Testicular Torsion: A Systematic Review of


Surgical Technique

Sacha L. Moore a,b, Ryad Chebbout a, Marcus Cumberbatch a,c, Jasper Bondad a,d, Luke Forster a,e,
Jane Hendry a,f, Ben Lamb a,g, Steven MacLennan a,h, Arjun Nambiar a,i, Taimur T. Shah a,j,
Vasilis Stavrinides a,k, David Thurtle a,l, Ian Pearce a,m, Veeru Kasivisvanathan a,n,o,*
a b
British Urology Researchers in Surgical Training (BURST) Research Collaborative, UK; North Wales Clinical Research Centre/Wrexham Maelor Hospital,
Betsi Cadwaladr University Health Board, Wales, UK; c Department of Urology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK; d Depart-
e
ment of Urology, Lister Hospital, Stevenage, UK; Department of Urology, Royal Free Hospital, London, UK; f Department of Urology, Queen Elizabeth
University Hospital, Glasgow, Scotland, UK; Department of Urology, Cambridge University Hospitals NHS Foundation Trust, UK; h Academic Urology Unit,
g

University of Aberdeen, Scotland, UK; i Department of Urology, Freeman Hospital, Newcastle-upon-Tyne, UK; j Charing Cross Hospital, Imperial College
k
Healthcare NHS Trust and Imperial Prostate, Department of Surgery and Cancer, Imperial College London, UK; Division of Surgery and Interventional
l m
Science, University College London, UK; Academic Urology Group, Department of Surgery, University of Cambridge, Cambridge, UK; Manchester Royal
n
Infirmary, Manchester University NHS Foundation Trust, Manchester, UK; Division of Surgery and Interventional Science, University College London,
London, UK; o Department of Urology, University College London Hospital, London, UK

Article info Abstract

Article history: Context: Acute testicular torsion is a common urological emergency. Accepted practice
Accepted July 31, 2020 is surgical exploration, detorsion, and orchidopexy for a salvageable testis.
Objective: To critically evaluate the methods of orchidopexy and their outcomes with a
Associate Editor: Richard Lee view to determining the optimal surgical technique.
Evidence acquisition: This review protocol was published via PROSPERO
[CRD42016043165] and conducted in accordance with the Preferred Reporting Items
Keywords: for Systematic Reviews and Meta-analyses (PRISMA). EMBASE, MEDLINE, and CENTRAL
Testicular torsion databases were searched using the following terms: “orchidopexy”, “fixation”, “explo-
Orchidopexy ration”, “torsion”, “scrotum”, and variants. Article screening was performed by two
reviewers independently. The primary outcome was retorsion rate of the ipsilateral
Surgical technique testis following orchidopexy. Secondary outcomes included testicular atrophy and
Systematic review fertility.
Evidence synthesis: To our knowledge, this is the first systematic review on this topic.
The search yielded 2257 abstracts. Five studies (n = 138 patients) were included. All five
techniques differed in incision and/or type of suture and/or point(s) of fixation. Post-
operative complications were reported in one study, and included scrotal abscess in 9.1%
and stitch abscess in 4.5%. The contralateral testis was fixed in 57.6% of cases. Three
studies reported follow-up duration (range 6–31 wk). No study reported any episodes of
ipsilateral retorsion. In the studies reporting ipsilateral atrophy rate, this ranged from
9.1% to 47.5%. Fertility outcomes and patient-reported outcome measures were not
reported in any studies.
Conclusions: There is limited evidence in favour of any one surgical technique for acute
testicular torsion. During the consent process for scrotal exploration, uncertainties in
long-term harms should be discussed. This review highlights the need for an interim

* Corresponding author. University College London Hospital, London, UK.


E-mail address: veeru.kasi@ucl.ac.uk (V. Kasivisvanathan).

https://doi.org/10.1016/j.euf.2020.07.006
2405-4569/© 2020 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
Eur Urol Focus (2020), https://doi.org/10.1016/j.euf.2020.07.006
EUF-967; No. of Pages 11

2 E U RO P E A N U RO L O GY F O C U S X X X ( 2 019 ) X X X– X X X

consensus on surgical approach until robust studies examining the effects of an operative
approach on clinical and fertility outcomes are available.
Patient summary: Twisting of blood supply to the testis, termed testicular torsion, is a
urological emergency. Testicular torsion is treated using an operation to untwist the cord
that contains the blood vessels. If the testis is still salvageable, surgery can be performed
to prevent further torsion. The method that is used to prevent further torsion varies. We
reviewed the literature to assess the outcomes of using various surgical techniques to fix
the twisting of the testis. Our review shows that there is limited evidence in favour of any
one technique.
© 2020 European Association of Urology. Published by Elsevier B.V. All rights reserved.

1. Introduction 2. Evidence acquisition

Testicular torsion is a common urological and paediat- 2.1. Protocol and registration
ric emergency, and results in ischaemia due to twisting
of the spermatic cord and thus interruption of blood The protocol of this study was decided a priori and pub-
flow [1]. It accounts for around 17–35% of patients lished on the online systematic review register PROSPERO
presenting with an acute scrotum and affects up to (registration number: CRD42016043165).
4.5 in every 100 000 men below the age of 25 yr each
year, with peaks of incidence during the perinatal and 2.2. Eligibility criteria
pubertal ages [2–5]. The anatomical configuration of a
“bell clapper” deformity is commonly cited as a predis- All studies reporting orchidopexy indicated for acute testic-
posing factor, and other proposed mechanisms include ular torsion in an adult and/or paediatric population were
physical activity (eg, cycling), trauma, or genetic inher- considered for inclusion. In order to be eligible for inclusion,
itance [2,6–8]. If untreated, testicular torsion will result studies were required to report the detailed surgical tech-
in permanent ischaemic injury [9,10]; thus, suspected nique used to perform the orchidopexy along with data
testicular torsion requires immediate surgical explora- pertaining to at least one of the stated outcome measures
tion [3]. specified below. Surgical technique was deemed to include
On surgical exploration, testicular torsion, can usually be the approach, suture type, number of points of fixation,
subdivided into intra- and extravaginal subtypes anatomic location of fixation points, and use of the Jaboulay
[1]. Time to presentation is crucially important, with pain pouch or vaginalis patch technique. The Jaboulay pouch
lasting >4–8 h being highly associated with testicular death technique refers to the excision and eversion of the tunica
without intervention [2]. In approximately one in three vaginalis. The vaginalis patch technique refers to the use of a
cases, the testis is considered dead resulting in orchidec- tunica vaginalis patch graft during the procedure. Included
tomy (orchiectomy) [11,12]. Following surgical exploration studies were permitted to be interventional or observa-
and detorsion, a salvageable testis will undergo orchido- tional and retrospective or prospective. An interventional
pexy (orchiopexy), and usually the contralateral testis will study refers to any study that involves exposing study
also undergo orchidopexy [13]. participants to a specific treatment with the outcome mea-
The literature on orchidopexy technique is heteroge- sured. An observational study refers to any study describing
neous and scarce, with variation reported in the type of outcomes from current/routine practice, whether that be in
suture use, fixation methods, synchronous procedures, and a prospective or retrospective manner.
contralateral testicular fixation. Recurrent ipsilateral or Studies reporting orchidopexy indicated for anything
contralateral torsion, testicular ischaemia and atrophy, other than acute testicular torsion, for example, crypto-
and negative impacts on fertility have all been reported chordism or intermittent testicular torsion, were excluded.
as possible complications after orchidopexy [14,15]. Despite Any data pertaining to orchidopexy in neonates (age <30 d)
these complications, the significant potential for avoidable was not included. When data could not be used to answer at
harm, and possible medicolegal implications resulting from least one of the stated primary or secondary outcomes, the
suboptimal management, there is a paucity in published study was not included. Case reports, reviews, comments,
synthesis of evidence comparing the different surgical tech- editorials, abstracts, or conference proceedings were
niques [16]. excluded.
The aim of this study was to describe, summarise, and
evaluate the published data reporting surgical technique 2.3. Outcomes
and subsequent outcomes of orchidopexy indicated for
acute testicular torsion with a view to determining the The primary outcome was torsion recurrence rate of the
optimal surgical technique. ipsilateral testicle following orchidopexy for acute testicular

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
Eur Urol Focus (2020), https://doi.org/10.1016/j.euf.2020.07.006
EUF-967; No. of Pages 11

E U R O P E A N U R O L O GY F O C U S X X X ( 2 019 ) X X X– X X X 3

torsion. Acute testicular torsion was defined as presentation between reviewers, a pilot of a random selection of the
of an acute scrotum with confirmed testicular torsion found abstracts and full papers was first screened by all authors
intraoperatively. Torsion recurrence was defined as a re- before initiation of the real screening process. Any conflicts
presentation of acute testicular torsion of the previously in decisions were resolved by an author (M.C.). Reference
fixated testicle. lists of key studies in the field were hand searched for other
Secondary outcomes included testicular atrophy of relevant studies.
ipsilateral testicle, ipsilateral torsion recurrence rate,
contralateral torsion, testicular atrophy of the contralat- 2.6. Data extraction and synthesis
eral testicle following orchidopexy, and fertility outcomes
following orchidopexy for testicular torsion. Testicular A data collection pro forma was designed with input from all
atrophy was defined by new reduction in size in compar- authors a priori, with desired data fields based on study
ison with contralateral testicle found on clinical exami- outcomes and predicted sources of heterogeneity and con-
nation and/or Doppler ultrasound. Fertility was inferred founding variables. Data were extracted independently by
from changes in serum hormone markers and/or semen two authors, with any conflicts in data extraction resolved
analysis/spermiogram [15,17,18]. by a third author (M.C.).
Data were collected for the following fields: study design,
2.4. Search strategy demographic data, intraoperative details, surgical technique,
follow-up, and outcome results. Study design data included
The EMBASE, MEDLINE, and CENTRAL literature bases were methodology, year of publication, number of patients, and
searched using the following search terms, combined using number of orchidopexies. Demographic data included previ-
Boolean operators as appropriate: “orchiopexy”, “orchido- ous testicular surgery, and surgeon specialty and experience.
pexy”, “fixation”, “exploration”, “spermatic cord torsion”, Intraoperative data included anaesthetic type, testicle colour,
“torsion”, “scrotum”, and “acute scrotum”. No limits were mean degree of torsion, active bleeding, and operation dura-
applied to the search, and the search was duplicated by two tion. The exact wording of the surgical technique of each
authors independently to ensure identical results. article was recorded, as well as specific information on the
operative approach, suture material, suture size, number of
2.5. Study selection sutures, points of fixation, removal of testicular appendage,
use of the Jaboulay procedure or vaginal patch technique, and
A team of six authors independently screened the abstracts contralateral testicle fixation. Follow-up type, frequency, and
and full papers using the online systematic review platform duration were recorded, and data pertaining to the primary
Covidence (www.covidence.org). To ensure consistency and secondary outcomes were detailed.

Records identified through Additional records identified


database searching through other sources
(n = 2257) (n = 1)

Abstracts screened Records excluded


(n = 2258) (n = 2127)

Full-text articles excluded


Full-text articles (n = 124)
assessed for eligibility
(n = 131)
- Surgical technique not
described (n = 41)
- Incorrect outcomes (n = 36)
- Incorrect study design
Studies included in (n = 29)
qualitative synthesis
(n = 7)

Fig. 1 – PRISMA diagram. PRISMA = Preferred Reporting Items for Systematic Reviews and Meta-analyses.

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
Eur Urol Focus (2020), https://doi.org/10.1016/j.euf.2020.07.006
EUF-967; No. of Pages 11

4 E U RO P E A N U RO L O GY F O C U S X X X ( 2 019 ) X X X– X X X

2.7. Risk of bias period, three studies reviewed notes dating back over a 10-yr
period, whilst one study reviewed back over a 6-yr period, one
A full risk of bias assessment was undertaken using the over a 2-yr period, and one over a 1-yr period.
ROBINS-1 tool as per the Cochrane collaboration guidelines. A total of 182 patients were included in this review
(range 10–65 patients). Two studies reported mean age that
3. Evidence synthesis can be attributed to the included cohort only (10.1 and
14.0 yr) [21,23]. The total number of orchidopexies was
3.1. Demographics 266 (range 19–92 procedures). Out of 182 patients, 105
(57.7%) underwent contemporaneous bilateral orchidopexy.
The search was conducted in accordance with the Preferred Risk of bias assessment using ROBINS-I highlighted a
Reporting Items for Systematic Reviews and Meta-analyses high risk of bias in all studies (Figs. 2 and 3).
(PRISMA) guidelines and yielded 2257 results, with seven
studies suitable for inclusion (Fig. 1) [19–25]. Publication 3.2. Operative technique
year ranged from 1975 to 2012, with three UK-based studies,
two US-based studies, one Jamaican study, and one German The exact procedure for each method of orchidopexy is
study. Four studies were from urology department settings, described in Table 1. Three studies reported using nonab-
two from paediatric surgery settings, and one from a gen- sorbable sutures [19,20,23], whilst one reported using
eral surgery setting. Six of the seven studies were retro- absorbable sutures [22], one reported using both [25],
spective. One study reviewed notes dating back over a 14-yr one reported eversion and suturing of the tunica vaginalis

Fig. 2 – Summary of risk of bias assessments across all studies undertaken using the ROBINS-1 criteria.

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
Eur Urol Focus (2020), https://doi.org/10.1016/j.euf.2020.07.006
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E U R O P E A N U R O L O GY F O C U S X X X ( 2 019 ) X X X– X X X 5

Fig. 3 – Graph for risk of bias assessments undertaken using the ROBINS-1 criteria.

B D

Fig. 4 – A single vertical incision is shown along the median raphe. The median septum is identified (A). A 2/0 Prolene suture is passed through the
tunica albuginea (B), and then vertically (C) through the septum and vertically through the contralateral testis (D). Adapted from Antao et al [23].

alone [21], and one did not report suture material None of the included studies reported any episodes of
[24]. Removal of testicular appendage was not reported ipsilateral retorsion or contralateral torsion, regardless of
in any of the studies. The Jaboulay technique was reported the surgical approach. Ipsilateral testicular atrophy at fol-
to have been undertaken in three studies [21,22,25], whilst low-up was noted in two studies; Greaney [19] reported this
one study reported vaginalis patch [24]. Figures 4–10 dem- in 2/22 (9.1%) patients, whilst Figueroa et al [24] reported
onstrate some of the key differences between techniques this in 28/65 (47.5%) patients. Figueroa et al’s [24] study was
described (where enough detail on operative technique was the only study that defined testicular atrophy; this was
provided to allow for accurate reproduction of diagrams). described as 50% volume loss. Of the patients, 57.7%
underwent contralateral fixation by various methods; none
3.3. Outcome data of the included studies reported contralateral torsion. Fer-
tility outcomes were not recorded in six of seven of the
The mean duration of torsion was reported only by Figueroa included studies. Though Lent and Stephani [21] reported
et al [24]; this was 13.4 h. fertility outcomes, the series included some patients who
Three studies documented clinic follow-up that could be underwent orchidopexy for reasons other than acute tes-
attributed to the included cohort; this ranged from 6 to ticular torsion, so it was not possible to relate outcomes to
31 wk after surgery [22–24]. The paper by Lent and Stephani those who had acute testicular torsion. Immediate postop-
[21] reported follow-up for 27 patients with a mean follow- erative complications were discussed in one study [19]; this
up of 61/2 yr; however, it cannot be discerned whether this reported three patients with localised inflammation, two
includes all patients (32/35) who had undergone treatment patients who developed scrotal abscesses, and one patient
for acute testicular torsion rather than another indication. who developed a stitch abscess.

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
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EUF-967; No. of Pages 11


Table 1 – Summary of included studies and outcomes.
Eur Urol Focus (2020), https://doi.org/10.1016/j.euf.2020.07.006
Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.

u Design Surgical technique N Age Degree Complications Mean length Ipsilateral Ipsilateral
of torsion of follow- retorsion testicular
up (wk) rate (%) atrophy

Greaney (1975) [19] Retrospective case Incision: NR 22 NR NR Local inflammation NR 0 2


series (3/22, 13.6%)
Fixation: interrupted thread sutures to Scrotal abscess f
maintain upright position ormation (2/22, 9.1%)
Closure: eversion of tunica vaginalis, scrotum Stich abscess
closed with catgut to the dartos and clips to (1/22, 4.5%)
skin
Douglas (1988) [20] Retrospective case Incision: transverse incision to scrotum and 36 NR NR 0 NR 0 NR
series tunica vaginalis
Fixation: 4-0 nonabsorbable suture

E U RO P E A N U RO L O GY F O C U S X X X ( 2 019 ) X X X– X X X
Closure: tunica albuginea incorporated into
tunica vaginalis during closure
Lent (1993) [21] Retrospective case Incision: transverse incision to scrotum and 32a NR NR NR NR 0 0
series tunica vaginalis
Fixation: a continuous suture to the margins of
the tunica vaginalis communis without
additional fixation to the testis
Closure: NR
Redman (1995) [22] Prospective case series Incision: NR 11 14.0 NR 0 26 0 0
Fixation: dartos pouch created. External
spermatic fascia sutured to cut the edge of
tunica vaginalis covering the dorsal aspect of
the cord with interrupted or running 4-0 or 5-0
absorbable suture
Closure: running suture of 4-0 or
keropolyglacth suture, approximating the
tunica dartos with inclusion of the
immediately underlying ventral tunica
vaginalis. The skin is closed with 4-0 or 5-0
absorbable suture
Antao (2006) [23] Retrospective case Incision: single vertical scrotal incision along 10 NR NR 0 6 0 0
series the median raphe
Fixation: 2-0 nonabsorbable suture through
the tunica albuginea along the vertical axis of
the testis. Median scrotal septum is delivered
into the wound and a suture passed through its
lowest pole on both sides, and then through
the long axis of the other testis from lower to
upper via median septum
Closure: NR
Figueroa (2012) [24] Retrospective case Incision: anterior longitudinal incision through 59 10.1 NR 0 31 0 28
series tunica albuginea
Fixation: exact points of fixation—NR. Vaginalis
patch used as part of fixation/closure
Closure: NR
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Ipsilateral 3.4. Discussion


testicular
atrophy 3.4.1. Which surgical method or suture material has the lowest rate
NR of retorsion?
This review highlighted the wide variation in surgical
Ipsilateral
retorsion

approaches for orchidopexy. The key techniques reported


rate (%)

are described with diagrams in Figures 4–10. Our principal


findings were that in the 182 patients in this review, regard-
0

less of the surgical approach, there was no ipsilateral or


Mean length

contralateral retorsion with follow-up ranging from 6 to


of follow-

31 wk, whilst follow-up up to 15 yr was reported in the paper


up (wk)

by Lent and Stephani [21]. This would suggest that, in the


NR

short term at least, all techniques included were effective and


reasonable options for reducing the risk of retorsion. A num-
ber of case reports exist in the literature regarding retorsion
following orchidopexy in both animal and human models, but
Complications

as these are usually reported in low numbers, with a large


number of potential confounders, it is difficult to draw firm
conclusions on the association of one particular factor with
the likelihood of retorsion [17,18,26,27]. Absorbable sutures
0

in this study, 35 patients were included; however, three patients underwent orchidopexy for an indication other than acute testicular torsion.

have been reported to have a higher rate of failure, although


Sells et al [26] reported that this might be linked to the higher
of torsion

number of orchidopexies carried out using absorbable


Degree

sutures. None of the studies included in our review reported


NR

any ipsilateral torsion and, as such, appear equal in this


regard. Of note, Sells et al [26] hypothesised on the basis of
Age

animal studies [25,28–30] that the most important factor in


NR

adhesion formation is the direct apposition of tunica albugi-


nea to the scrotal wall, with greater adhesions seen with
12

tunica vaginalis eversion than with suture fixation of the


N

testis alone. Lent and Stephani [21] confirmed that tunica


NR = not reported or unable to accurately discern on the basis of the information provided in the text.

vaginalis eversion and suturing alone was a valid option,


polypropylene nonabsorbable sutures are then

through the dartos of the posterior scrotal wall.


polyglactin absorbable suture. One to three 4/0
Fixation: Jaboulay pouch technique using 3/0
Incision: vertical scrotal incision through the
median raphe followed by division of scrotal

placed through the everted tunica vaginalis.

continuous fashion and the edges of scrotal


One to three of the sutures are then placed

though authors have suggested that the anatomy conducive


layers. Parietal tunica vaginalis is opened

The sutures are tied once the testicle is

to torsion is not always corrected by eversion alone, so the


Closure: 3/0 polyglactin sutures in a

skin approximated with interrupted

addition of sutures might be preferable.


The use of testicular capsulotomy for the management of
testicular compartment syndrome is not specifically
reviewed in this study, although Figueroa et al [24] incorpo-
rated this method. Testicular capsulotomy has been demon-
Surgical technique

absorbable sutures

strated by Kutikov et al [31] to restore normal compartment


longitudinally

pressures in testicular compartment syndrome.


replaced

3.4.2. What are the atrophy rates of the ipsilateral testicle after
fixation?
Of the three studies reporting testicular atrophy, high rates
of atrophy were reported in two studies, with 9% and 43%
experiencing atrophy of the ipsilateral testis. The high
Retrospective case

atrophy rate (43%) in the study of Figueroa et al [24] may


be related to their decision to keep some testes despite
minimal improvement of vascularity after detorsion. This is
Design

series

likely to be common practice amongst the urological com-


munity, and testes that might typically be removed are
given an additional chance to be salvaged if there was
Table 1 (Continued )

improvement in the blood flow to the affected testis after


Mazaris (2012) [25]

a longitudinal incision of the tunica albuginea. This finding,


however, suggests that testicular atrophy may be an under-
reported outcome following orchidopexy and should be
considered more pertinently when counselling patients
u

for scrotal exploration.


a

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
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Fig. 5 – A large single transverse incision is made (A). A 3/0 Vicryl is passed through the tunica albuginea and the median septum (B) at three points
(C). Adapted from Hamdy et al. [38]. Although the study of Hamdy et al (1987) was excluded at the final stage due to having no prespecified primary or
secondary outcomes, pertinent learning points of the technique were learnt from this paper, and as such the technique is demonstrated above.

B
A

Fig. 6 – A small single transverse incision is made (C). A 4/0 nonabsorbable suture is passed through the tunica vaginalis (B) and the testis (A). Adapted
from Douglas [20].

Fig. 7 – An anterior longitudinal incision through tunica albuginea is made, with diagram demonstrating the use of a vaginalis patch as part of
fixation/closure to prevent compartment syndrome. Adapted from Figueroa et al [24].

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
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Fig. 8 – An incision is made at the cranial aspect of the scrotum (A). A dartos pouch is created (B), with external spermatic fascia sutured to the cut
edge of tunica vaginalis covering the dorsal aspect of the cord with interrupted or running 4-0 or 5-0 absorbable suture. Closure is with a running
suture of 4-0 or keropolyglacth suture, approximating the tunica dartos with inclusion of the immediately underlying ventral tunica vaginalis. Adapted
from Redman and Barthold [22].

B
A

Fig. 9 – A vertical scrotal incision through the median raphe is made. Eversion of the parietal layer of the tunica vaginalis is maintained using a
continuous 3/0 polyglactin suture. One to three 4/0 polypropylene sutures are then placed through the everted tunica (A) and into the dartos of the
posterior scrotal wall (B). Adapted from Mazaris et al [25].

3.4.3. Should the contralateral testicle always be fixed? like a reasonable approach to take to prevent future con-
Debate exists regarding contralateral fixation, with Arnb- tralateral torsion.
jörnsson and Kullendorff [32] arguing that the low risk of
contralateral torsion outweighs the risk of complications 3.4.4. What is the impact of surgical technique on fertility after an
from orchidopexy. In our series, 63.3% of patients under- episode of acute torsion?
went contralateral fixation by various methods; none of the None of the included studies, in which a specific technique
included studies reported any contralateral torsion, but only was included, reported on the fertility rates after orchido-
limited medium- and long-term outcome data were pexy for acute testicular torsion; thus, it is difficult to draw
reported in all included studies. The high number of con- conclusions on whether there are any differences between
tralateral orchidopexies is likely a reflection on both case different techniques. However, one study on eversion orch-
reports of contralateral torsion in cases where the contra- idopexy in 35 patients reported this, though it included
lateral testis was not fixed [27,32–34]. Whilst the exact risk three patients who underwent orchidopexy electively for
of contralateral torsion remains unknown, there is evidence prevention of torsion of the contralateral side and it was not
to suggest this risk; a series of 27 cases of testicular torsion possible to discern whether these fertility outcomes applied
in pubertal boys found that the contralateral testis was to only those who had orchidopexy for acute testicular
affected by the bell clapper deformity in 78% of cases torsion. Nonetheless, it is worthwhile reflecting on this
[1]. Based on this, contralateral orchidopexy would seem study. Twenty-seven patients were followed for an average

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
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10 E U RO P E A N U RO L O GY F O C U S X X X ( 2 019 ) X X X– X X X

Fig. 10 – A transverse incision is made (A). The tunica vaginalis communis is everted, the testis is detorted, the testicular structures are repositioned in
the scrotum without additional fixation (B), and the margins of the tunica vaginalis communis are sutured in a continuous fashion (C). Adapted from
Lent and Stephani [21].

of 6.5 yr and had paternity rates of 78% (7/9) in men wanting typically affects. As such, there is clearly a pressing need
to father children. Additionally, the effect of surgical to address the question of which surgical technique, if any,
approach on testicular atrophy (reported in up to 43.1% of causes least harm and best preserves adequate testicular
patients in our study) in relation to subsequent fertility was function. Given that this is one of the most important
not addressed in the included studies. A study by Arap et al emergencies that urologists deal with, the lack of high-
[35] found no significant difference in sperm count or quality data supporting specific surgical practice warrants
motility in patients who had previous orchidopexy for addressing with consensus meetings amongst experts in
testicular torsion versus healthy controls. In addition, a case the field and, if feasible, well-designed registries and
series by Gielchinsky et al identified pregnancy rates of studies.
>90% in patients undergoing bilateral orchidopexy or orchi-
dectomy and contralateral orchidopexy for testicular tor- 3.5. Strengths and limitations of our study
sion [36]. As the exact surgical techniques were not defined
within these studies, it is difficult to relate the findings to To our knowledge, this is the first systematic review asses-
one specific method of orchidopexy. Despite this, some sing the surgical technique for orchidopexy in testicular
studies have discussed the possibility of suturing through torsion and associated outcomes. Our review, carried out
the testis as a significant risk factor for spermatogenesis robustly according to the PRISMA guidelines, highlights the
disorders, whilst others have highlighted that ischaemic/ absence of quality data in this area and thus the lack of
reperfusion injury may compromise hormonal testicular evidence for the use of one particular surgical technique
function [15,37]. over another. It demonstrates a clear need for formal con-
sensus on this topic, and the need for future studies to
3.4.5. Summary address these deficiencies. However, this review has some
There is a significant degree of heterogeneity in design, limitations, including primarily the large degree of hetero-
reporting, and outcomes, and thus uncertainties in the geneity, high risk of bias, and poor reporting of outcomes in
optimal surgical technique and in long-term outcomes the included studies.
following orchidopexy should be considered when coun-
selling patients for scrotal exploration. Previously, Pearce 4. Conclusions
et al [3] suggested a protocol for the management of acute
testicular torsion following a survey of clinical practice; Our review demonstrates that there is currently very lim-
recommendations included bilateral orchidopexy, the use ited evidence in favour of any one surgical technique for
of three nonabsorbable sutures, removal of testicular acute testicular torsion, with a lack of long-term outcome
appendages, and no role for additional Jaboulay repair. data on all approaches. To counsel patients adequately and
Although this appears to be a reasonable protocol, there is obtain their consent regarding the implications of surgery
little evidence to back its clinical efficacy. It is likely that for testicular torsion, the uncertainties should be discussed.
information such as long-term effects of technique on There is a need for an interim consensus until a randomised
testicular size and fertility prognosis will be of paramount controlled trial examining the effects of the operative
importance to the young men whom this condition approach on clinical and fertility outcomes is available.

Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
Eur Urol Focus (2020), https://doi.org/10.1016/j.euf.2020.07.006
EUF-967; No. of Pages 11

E U R O P E A N U R O L O GY F O C U S X X X ( 2 019 ) X X X– X X X 11

Author contributions: Sacha L. Moore had full access to all the data in the [14] Bolln C, Driver CP, Youngson GG. Operative management of testic-
study and takes responsibility for the integrity of the data and the ular torsion: current practice within the UK and Ireland. J Pediatr
accuracy of the data analysis. Urol 2006;2:190–3.
Study concept and design: Kasivisvanathan, Pearce, Cumberbatch, [15] Coughlin MT, Bellinger MF, LaPorte RE, Lee PA. Testicular suture:
MacLennan, Shah, Chebbout. a significant risk factor for infertility among formerly cryptorchid
Acquisition of data: Chebbout, Cumberbatch, Bondad, Forster, Hendry, men. J Pediatr Surg 1998;33:1790–3.
Lamb, Nambiar, Stavrinides, Thurtle. [16] Osman NI, Collins GN. Urological litigation in the UK National
Analysis and interpretation of data: Chebbout, Cumberbatch, Moore. Health Service (NHS): an analysis of 14 years of successful claims.
Drafting of the manuscript: Moore, Chebbout, Kasivisvanathan, Shah. BJU Int 2011;108:162–5.
Critical revision of the manuscript for important intellectual content: [17] Koochakzadeh S, Johnson K, Rich MA, Swana HS. Testicular torsion after
Moore, Cumberbatch, Bondad, Forster, Hendry, Lamb, MacLennan, Nam- previous surgical fixation. J Pediatr Surg Case Rep 2019;47:101225.
biar, Shah, Stavrinides, Thurtle, Pearce, Kasivisvanathan. [18] Chondros K, Chondros N. Recurrent testicular torsion after orchi-
Statistical analysis: None. dopexy. Pan Afr Med J 2015;20:190.
Obtaining funding: None. [19] Greaney G. Torsion of the testis: a review of 22 cases. Br J Surg
Administrative, technical, or material support: None. 1975;62:57–8.
Supervision: Pearce, Kasivisvanathan. [20] Douglas LL. Simple technique for testicular fixation in management
Other: None. of torsion. Urology 1988;XXXII:352–3.
[21] Lent V, Stephani A. Eversion of the tunica vaginalis for prophylaxis
of testicular torsion recurrences. J Urol 1993;150:1419–21.
Financial disclosures: Sacha L. Moore certifies that all conflicts of
[22] Redman JF, Barthold JS. A technique for atraumatic scrotal pouch
interest, including specific financial interests and relationships and
orchiopexy in the management of testicular torsion. J Urol
affiliations relevant to the subject matter or materials discussed in the
1995;154:1511–2.
manuscript (eg, employment/affiliation, grants or funding, consultan-
[23] Antao B, MacKinnon AE. Axial fixation of testes for prevention of
cies, honoraria, stock ownership or options, expert testimony, royalties,
recurrent testicular torsion. Surgeon 2006;4:20–1.
or patents filed, received, or pending), are the following: None.
[24] Figueroa V, Salle JLP, Braga LHP, et al. Comparative analysis of detor-
sion alone versus detorsion and tunica albuginea decompression
Funding/Support and role of the sponsor: None. (fasciotomy) with tunica vaginalis flap coverage in the surgical man-
agement of prolonged testicular ischemia. J Urol 2012;188:1417–23.
[25] Mazaris E, Tadtayev S, Shah T, Boustead G. Surgery illustrated Focus
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Please cite this article in press as: Moore SL, et al. Orchidopexy for Testicular Torsion: A Systematic Review of Surgical Technique.
Eur Urol Focus (2020), https://doi.org/10.1016/j.euf.2020.07.006

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