SKETCHY MICRO

I. Bacteria
CHAPTER 1 GRAM POSITIVE COCCI

□ 1.1 - Staphylococcus aureus

□ 1.2 - Staphylococcus epidermidis & saprophyticus
□ 1.3 - Streptococcus pyogenes (group A strep)
□ 1.4 - Streptococcus agalactiae (group B strep)
□ 1.5 - Streptococcus pneumoniae & viridans
□ 1.6 - Enterococcus faecium & faecalis
CHAPTER 2 GRAM POSITIVE BACILLI

□ 2.1 - Bacillus anthracis & cereus

□ 2.2 - Clostridium tetani
□ 2.3 - Clostridium botulinum
□ 2.5 - Clostridioides Difficile
□ 2.5 - Clostridium perfringens
□ 2.6 - Corynebacterium diphtheriae
□ 2.7 - Listeria monocytogenes
CHAPTER 3 GRAM-POSITIVE BRANCHING FILAMENTOUS RODS

□ 3.1 - Actinomyces israelii

□ 3.2 - Nocardia asteroides
CHAPTER 4 GRAM-NEGATIVE COCCI

□ 4.1 - Neisseria overview

□ 4.2 - Neisseria meningitidis
□ 4.3 - Neisseria gonorrhoeae
CHAPTER 5 GRAM-NEGATIVE BACILLI - ENTERIC TRACT

□ 5.1 - Klebsiella pneumoniae, Enterobacter spp., Serratia marcescens

□ 5.2 - Salmonella enteritidis & typhi
□ 5.3 - Shigella spp.
□ 5.4 - Escherichia coli (ETEC, EHEC)
□ 5.5 - Yersinia enterocolitica & pestis
□ 5.6 - Campylobacter jejuni
□ 5.7 - Vibrio spp.
□ 5.8 - Helicobacter pylori
□ 5.9 - Proteus mirabilis

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CHAPTER 6 GRAM-NEGATIVE BACILLI - RESPIRATORY TRACT

□ 6.1 - Bordetella pertussis

□ 6.2 - Haemophilus influenzae
□ 6.3 - Legionella pneumophila
□ 6.4 - Pseudomonas aeruginosa
CHAPTER 7 GRAM-NEGATIVE BACILLI - ZOONOTICS

□ 7.1 - Bartonella henselae

□ 7.2 - Brucella spp.
□ 7.3 - Francisella tularensis
□ 7.4 - Pasteurella multocida
CHAPTER 8 MYCOBACTERIA

□ 8.1 - Mycobacterium tuberculosis

□ 8.2 - Mycobacterium leprae
CHAPTER 9 SPIROCHETES

□ 9.1 - Borrelia burgdorferi

□ 9.2 - Leptospira interrogans
□ 9.3 - Treponema pallidum
CHAPTER 10 GRAM-INDETERMINATE BACTERIA

□ 10.1 - Chlamydia trachomatis, Chlamydophila pneumoniae & Chlamydophila psittaci

□ 10.2 - Coxiella burnetii
□ 10.3 - Gardnerella vaginalis
□ 10.4 - Mycoplasma pneumoniae
□ 10.5 - Rickettsia overview
□ 10.6 - Rickettsia prowazekii
□ 10.7 - Rickettsia rickettsia

II. Viruses
CHAPTER 1 RNA VIRUSES - POSITIVE SENSE

□ 1.1 - Picornaviridae overview

□ 1.2 - Poliovirus (Picornaviridae)
□ 1.3 - Coxsackievirus A & B (Picornaviridae)
□ 1.4 - Rhinovirus (Picornaviridae)
□ 1.5 - Hepatitis A virus (Picornaviridae)

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□ 1. 6- Norovirus/Norwalk virus (Caliciviridae)

□ 1.7 - Flaviviridae overview
□ 1.8 - Hepatitis C virus (Flaviviridae)
□ 1.9 - Eastern/Western/Venezuelan equine encephalitis virus, Rubella virus (Togaviridae)
□ 1.10 - Coronavirus (Coronaviridae)
□ 1.11 - HIV Part 1: Overview (Retroviridae)
□ 1.12 - HIV Part 2: Life Cycle
CHAPTER 2 RNA VIRUSES - NEGATIVE SENSE

□ 2.1 - Influenzavirus (Orthomyxoviridae)

□ 2.2 - Measles virus, mumps virus, respiratory syncytial virus, parainfluenza virus
(Paramyxoviridae)
□ 2.3 - Rabies virus (Rhabdoviridae)
□ 2.4 - Ebolavirus, Marburgvirus (Filoviridae)
□ 2.5 - Hantavirus, California encephalitis virus, Rift Valley fever virus (Bunyaviridae)
□ 2.6 - Lymphocytic choriomeningitis virus (Arenaviridae)
□ 2.7 - Rotavirus, Colorado tick fever virus (Reoviridae)
CHAPTER 3 DNA VIRUSES

□ 3.1 - Herpes simplex virus type 1 & 2 (Herpesviridae)

□ 3.2 - Epstein–Barr virus (Herpesviridae)
□ 3.3 - Cytomegalovirus (Herpesviridae)
□ 3.4 - Varicella-zoster virus (Herpesviridae)
□ 3.5 - HHV-6, roseola (Herpesviridae)
□ 3.6 - HHV-8, Kaposi's sarcoma (Herpesviridae)
□ 3.7 - JC polyomavirus, BK polyomavirus (Polyomaviridae)
□ 3.8 - Human papillomavirus (Papillomaviridae)
□ 3.9 - Parvovirus B19 (Parvoviridae)
□ 3.10 - Adenovirus (Adenoviridae)
□ 3.11 - Smallpox virus, Cowpox virus, Molluscum contagiosum virus (Poxviridae)
□ 3.12 - Hepatitis B virus (Hepadnaviridae)

III. Fungi
CHAPTER 1 SYSTEMIC MYCOSES

□ 1.1 - Histoplasma capsulatum

□ 1.2 - Blastomyces dermatitidis

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□ 1.3 - Coccidioides immitis

□ 1.4 - Paracoccidioides brasiliensis
CHAPTER 2 CUTANEOUS MYCOSES

□ 2.1 - Malassezia furfur

□ 2.2 - Epidermophyton spp., Trichophyton spp., Microsporum spp. (dermatophytes)
□ 2.3 - Sporothrix schenckii
CHAPTER 3 OPPORTUNISTIC FUNGAL INFECTIONS

□ 3.1 - Candida albicans

□ 3.2 - Aspergillus fumigatus
□ 3.3 - Cryptococcus neoformans
□ 3.4 - Mucor spp., Rhizopus spp. (mucormycetes)
□ 3.5 - Pneumocystis jirovecii

IV. Parasites
CHAPTER 1 PROTOZOA OF THE INTESTINAL TRACT

□ 1.1 - Giardia lamblia

□ 1.2 - Entamoeba histolytica
□ 1.3 - Cryptosporidium spp.
CHAPTER 2 PROTOZOA OF THE CNS

□ 2.1 - Toxoplasma gondii

□ 2.2 - Trypanosoma brucei
□ 2.3 - Naegleria fowleri
CHAPTER 3 PROTOZOA OF THE BLOOD

□ 3.1 - Trypanosoma cruzi

□ 3.2 - Babesia spp.
□ 3.3 - Plasmodium Part 1
□ 3.4 - Plasmodium Part 2: Treatment and PPX
□ 3.5 - Leishmania braziliensis & donovani
CHAPTER 4 PROTOZOA - OTHER TISSUE

□ 4.1 - Trichomonas Vaginalis

CHAPTER 5 HELMINTHS - NEMATODES

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□ 5.1 - Enterobius vermicularis, Ancylostoma duodenale, Necator americanus, Ascaris

lumbricoides, Strongyloides stercoralis, Trichinella spiralis (intestinal nematodes)

□ 5.2 - Dracunculus medinensis, Wuchereria bancrofti, Onchocerca volvulus, Toxocara

canis, Loa loa (tissue nematodes)
CHAPTER 6 HELMINTHS - TREMATODES AND CESTODES

□ 6.1 - Cestodes
□ 6.2 - Trematodes

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I. Autonomic Drugs
CHAPTER 1 PARASYMPATHETIC

□ 1.1 - Cholinomimetics
□ 1.2 - Acetylcholinesterase Inhibitors
□ 1.3 - Muscarinic antagonists
CHAPTER 2 SYMPATHETIC

□ 2.1 - Sympathomimetics
□ 2.2 - Indirect sympathomimetics
□ 2.3 - Alpha drugs
□ 2.4 - Beta blockers

II. Cardiovascular & Renal

CHAPTER 1 HEART FAILURE DRUGS

□ 1.1 - Digoxin, milrinone, nesiritide

□ 1.2 - ACE inhibitors, ARBs, Aliskiren

CHAPTER 2 DIURETICS

□ 2.1 - Acetazolamide, mannitol

□ 2.2 - Loop diuretics
□ 2.3 - Thiazides
□ 2.4 - K+ sparing diuretics

CHAPTER 3 ANTIHYPERTENSIVES

□ 3.1 - Calcium channel blockers

□ 3.2 - Primary hypertension & hypertensive emergency

CHAPTER 4 ANTIARRHYTHMICS

□ 4.1 - Class I A-C

□ 4.2 - Class II
□ 4.3 - Class III
□ 4.4 - Class IV
□ 4.5 - Class V

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III. Blood & Inflammation

CHAPTER 1 ANTICOAGULANTS & THROMBOLYTICS

□ 1.1 - Heparin, LMWH, fondaparinux, direct thrombin inhibitors, Xa inhibitors

□ 1.2 - Warfarin
□ 1.3 - Antiplatelet agents
□ 1.4 - Thrombolytics

CHAPTER 2 DYSLIPIDEMIA DRUGS

□ 2.1 - Statins
□ 2.2 - Cholestyramine, ezetimibe
□ 2.3 - Fibrates, niacin

CHAPTER 3 ANTI-INFLAMMATORY

□ 3.1 - NSAIDs
□ 3.2 - Gout drugs

IV. Smooth Muscle

CHAPTER 1 VASOACTIVE

□ 1.1 - Nitrates
□ 1.2 - Triptans & migraine
□ 1.3 - Prostaglandins, prostacyclin, bosentan, PDE5 inhibitors

CHAPTER 2 ALLERGY & PULMONARY

□ 2.1 - Antihistamines
□ 2.2 - Asthma therapy

V. GI & Endocrine
CHAPTER 1 GI

□ 1.1 - Antiemetic Agents

□ 1.2 - H2 receptor blockers, PPIs
□ 1.3 - Laxatives & antidiarrheal agents

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CHAPTER 2 DIABETES

□ 2.1 - Insulin, sulfonylureas, meglitinides, GLP-1 agonists, DPP-4 inhibitors

□ 2.2 - Metformin, thiazolidinediones, pramlintide, SGLT2 inhibitors

CHAPTER 3 THYROID, PARATHYROID & ADRENAL

□ 3.1 - Propylthiouracil, methimazole, levothyroxine

□ 3.2 - Bisphosphonates, raloxifene, denosumab, calcitonin
□ 3.3 - Teriparatide, vitamin D, cinacalcet, sevelamer
□ 3.4 - Glucocorticoids

CHAPTER 4 HYPOTHALAMIC & PITUITARY

□ 4.1 - Growth hormone, mecasermin, octreotide, pegvisomant

□ 4.2 - ADH, DDAVP, ADH receptor antagonists

VI. Neuro/Psych
CHAPTER 1 SEDATIVE-HYPNOTICS

□ 1.1 - Benzodiazepines, flumazenil

□ 1.2 - Nonbenzodiazepine hypnotics, melatonin, ramelteon
□ 1.3 - Barbiturates
CHAPTER 2 ANESTHETICS & ANALGESICS

□ 2.1 - Propofol, etomidate, ketamine

□ 2.2 - Inhaled anesthetics, dantrolene
□ 2.3 - Opiates, naloxone, naltrexone
CHAPTER 3 ANTIDEPRESSANTS & ANXIOLYTICS

□ 3.1 - SSRIs, SNRIs, cyproheptadine

□ 3.2 - Tricyclic antidepressants
□ 3.3 - MAO inhibitors
□ 3.4 - Bupropion, mirtazapine, trazodone

CHAPTER 4 MOOD STABILIZERS & ANTIEPILEPTIC DRUGS

□ 4.1 - Lithium
□ 4.2 - Valproate, topiramate, lamotrigine, levetiracetam
□ 4.3 - Carbamazepine, phenytoin, gabapentin, tiagabine, vigabatrin
□ 4.4 – Ethosuximide

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CHAPTER 5 ANTIPSYCHOTICS & PARKINSON'S

□ 5.1 - First generation antipsychotics

□ 5.2 - Second generation antipsychotics
□ 5.3 - Levodopa/carbidopa, entacapone, tolcapone, selegiline, ropinirole, pramipexole,
amantadine

VII. Antimicrobials
CHAPTER 1 CELL WALL AND MEMBRANE ACTIVE ANTIBIOTICS

□ 1.1 - Penicillin
□ 1.2 - Nafcillin, Oxacillin, Methicillin & Dicloxacillin
□ 1.3 - Ampicillin, Amoxicillin, Piperacillin, Ticarcillin
□ 1.4 - Cephalosporins
□ 1.5 - Monobactams & Carbapenems
□ 1.6 - Vancomycin
□ 1.7 - Daptomycin

CHAPTER 2 INHIBITORS OF BACTERIAL PROTEIN SYNTHESIS

□ 2.1 - Tetracyclines
□ 2.2 - Macrolides
□ 2.4 - Clindamycin
□ 2.5 - Chloramphenicol
□ 2.6 - Linezolid
□ 2.7 - Aminoglycosides

CHAPTER 3 ANTIMYCOBACTERIALS

□ 3.1 - Tuberculosis Drugs

□ 3.2 - Leprosy drugs

CHAPTER 4 OTHER ANTIBIOTICS

□ 4.1 - Trimethoprim/Sulfamethoxazole
□ 4.2 - Fluoroquinolones
□ 4.3 - Metronidazole

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CHAPTER 5 ANTIFUNGALS

□ 5.1 - Amphotericin, flucytosine

□ 5.2 - Azoles
□ 5.3 - Griseofulvin, Terbinafine, Echinocandins

CHAPTER 6 ANTIVIRALS: HIV

□ 6.1 - NRTIs
□ 6.2 - NNRTIs
□ 6.3 - Protease inhibitors
□ 6.4 - Maraviroc, fusion inhibitors, integrase inhibitors

CHAPTER 7 ANTIVIRALS: OTHER

□ 7.1 - Acyclovir, valacyclovir, famciclovir

□ 7.2 - Ganciclovir, valganciclovir, foscarnet, cidofovir

VIII. Antineoplastics
CHAPTER 1 ANTIMETABOLITES

□ 1.1 - Methotrexate, leucovorin, 5-fluorouracil, hydroxyurea

□ 1.2 - Azathioprine, 6-mercaptopurine, mycophenolate mofetil
□ 1.3 - Cladribine, cytarabine, gemcitabine

CHAPTER 2 DNA & CELLULAR DIVISION

□ 2.1 - Cyclophosphamide, ifosfamide, busulifan, nitrosoureas (carmustine, lomustine,

streptozocin)
□ 2.2 - Cisplatin, carboplatin, oxaliplatin, amifostine
□ 2.3 - Bleomycin, doxorubicin, daunorubicin, actinomycin D
□ 2.4 - Etoposide, teniposide, topotecan, irinotecan
□ 2.5 - Vincristine, vinblastine, paclitaxel

CHAPTER 3 KINASE INHIBITORS & MONOCLONAL ANTIBODIES

□ 3.1 - Imatinib, erlotinib, sorafenib, sunitinib, vemurafenib

□ 3.2 - Rituximab, cetuximab, bevacizumab, alemtuzumab, trastuzumab

CHAPTER 4 IMMUNOLOGY

□ 4.1 - Interferon α, β, γ

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I. Cardiac
CHAPTER 1 ISCHEMIC HEART DISEASE

□ 1.1 - Myocardial Response To Ischemia

□ 1.2 - Stable Angina, Vasospastic Angina, & Acute Coronary Syndromes (UA, NSTEMI, STEMI)
□ 1.3 - Acute Myocardial Infarction & Post-MI Timeline

CHAPTER 2 HEART FAILURE

□ 2.1 - Congestive Heart Failure - Pathophysiology

□ 2.2 - Congestive Heart Failure - Clinical Manifestations

CHAPTER 3 MYOCARDIAL & PERICARDIAL DISORDERS

□ 3.1 - Dilated and Restrictive Cardiomyopathy

□ 3.2 - Hypertrophic Cardiomyopathy
□ 3.3 - Myocarditis
□ 3.4 - Pericarditis & Constrictive Pericarditis

CHAPTER 4 VALVULAR DISORDERS

□ 4.1 - Mitral Stenosis, Acute Rheumatic Fever & Rheumatic Heart Disease
□ 4.2 - Mitral Valve Regurgitation and Prolapse
□ 4.3 - Aortic Stenosis and Regurgitation

CHAPTER 5 CONGENITAL HEART DISEASE

□ 5.1 - Left-to-Right Shunts

□ 5.2 - Right-to-Left Shunts

II. Vascular
CHAPTER 1 ATHEROSCLEROSIS

□ 1.1 - Atherosclerosis: Pathophysiology

□ 1.2 - Peripheral Artery Disease

CHAPTER 2 HYPERTENSION

□ 2.1 - Hypertension
□ 2.2 - Aortic Aneurysm
□ 2.3 - Aortic Dissection

CHAPTER 3 VASCULITIDES

□ 3.1 - Large & Medium Vessel Vasculitides

□ 3.2 - Small Vessel Vasculitides

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III. Pulmonary
CHAPTER 1 OBSTRUCTIVE LUNG DISEASE

□ 1.1 - COPD & Emphysema

□ 1.2 - Asthma & Bronchiectasis

CHAPTER 2 RESTRICTIVE LUNG DISEASE

□ 2.1 - Restrictive Lung Disease (Overview)

□ 2.2 - Idiopathic Pulmonary Fibrosis
□ 2.3 - Pneumoconioses
□ 2.4 - Sarcoidosis & Berylliosis

CHAPTER 3 ACUTE LUNG DISORDERS

□ 3.1 - Pneumothorax
□ 3.2 - Acute Respiratory Distress Syndrome (ARDS)
□ 3.3 - Deep Vein Thrombosis & Pulmonary Embolism

CHAPTER 4 LUNG CANCER

□ 4.1 - Lung Carcinoma

IV. Renal
CHAPTER 1 ACUTE KIDNEY INJURY

□ 1.1 - Renal Function Tests & Acute Kidney Injury (AKI)

□ 1.2 - Acute Tubular Necrosis (ATN)
□ 1.3 - Tubulointerstitial Nephritis

CHAPTER 2 GLOMERULOPATHY

□ 2.1 - Nephrotic Syndrome

□ 2.2 - Nephritic Syndrome

CHAPTER 3 CONGENITAL & CHRONIC KIDNEY DISEASE

□ 3.1 - Congenital & Cystic Kidney Disease

□ 3.2 - Chronic Kidney Disease (CKD)

CHAPTER 4 URINARY TRACT OBSTRUCTION

□ 4.1 - Hydronephrosis & Urinary Tract Obstruction

□ 4.2 - Calcium Oxalate Stones & Calcium Phosphate Stones
□ 4.3 - Magnesium Ammonium Phosphate (MAP) Stones, Uric Acid Stones, & Cystine Stones

CHAPTER 5 RENAL CANCER

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□ 5.1 - Renal Cell Carcinoma & Nephroblastoma

CHAPTER 6 VOLUME, ELECTROLYTE & ACID/BASE DISORDERS

□ 6.1 - Osmolality & Sodium Disorders

□ 6.2 - Potassium Disorders
□ 6.3 - Calcium Disorders
□ 6.4 - Acid/Base Disorders
□ 6.5 - Renal Tubular Acidosis (RTA)

V. GI
CHAPTER 1 ESOPHAGEAL & GASTRIC DISORDERS

□ 1.1 - Structural Esophageal Disorders & GERD

□ 1.2 - Esophageal Dysmotility & Cancer
□ 1.3 - Acute and Chronic Gastritis & Peptic Ulcer Disease
□ 1.4 - Gastric Dysmotility & Cancer

CHAPTER 2 SMALL BOWEL DISORDERS

□ 2.1 - Small Bowel Obstruction, Ileus & Hernias

□ 2.2 - Carcinoid Tumor & Small Bowel Neoplasms
□ 2.3 - Intestinal Ischemia & Angiodysplasia
□ 2.4 - Congenital GI Disorders

CHAPTER 3 COLORECTAL & ANAL DISORDERS

□ 3.1 - Large Bowel & Appendiceal Disorders

□ 3.2 - Crohn's Disease & Ulcerative Colitis
□ 3.3 - Colorectal Polyps & Cancer
□ 3.4 - Anorectal Disorders

VI. Hepatobiliary
CHAPTER 1 GALLBLADDER & BILIARY TRACT DISEASE

□ 1.1 - Lab Evaluation of Liver Injury & Hyperbilirubinemia

□ 1.2 - Gallbladder & Biliary Tract Disease
□ 1.3 - Autoimmune Biliary Tract Disorders & Cancer

CHAPTER 2 LIVER DISEASE

□ 2.1 - Cirrhosis - Pathogenesis & Clinical Manifestations

□ 2.2 - Hereditary Hemochromatosis & Wilson's Disease
□ 2.3 - Alcoholic and Non-alcoholic Fatty Liver Disease

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□ 2.4 - Liver Tumors & Hepatocellular Carcinoma

CHAPTER 3 PANCREATIC DISEASE

□ 3.1 - Acute & Chronic Pancreatitis

□ 3.2 - Pancreatic Cancer & Islet Cell Tumors

VII. Endocrine
CHAPTER 1 HYPOTHALAMIC & PITUITARY DISORDERS

□ 1.1 - Hypothalamic & Pituitary Dysfunction - Etiologies

□ 1.2 - Hypothalamic & Pituitary Dysfunction - Clinical Manifestations
□ 1.3 - Hyperpituitarism
□ 1.4 - Diabetes Insipidus & SIADH

CHAPTER 2 ADRENAL DISORDERS

□ 2.1 - Adrenal Insufficiency

□ 2.2 - Congenital Adrenal Hyperplasia (CAH)
□ 2.3 - Adrenocortical Hyperfunction: Hyperaldosteronism & Hypercortisolism
□ 2.4 - Cushing's Syndrome
□ 2.5 - Pheochromocytoma & Neuroblastoma

CHAPTER 3 DIABETES

□ 3.1 - Diabetes Mellitus: Pathogenesis & Acute Clinical Manifestations

□ 3.2 - Diabetic Ketoacidosis (DKA) & Hyperosmolar Hyperglycemic State (HHS)
□ 3.3 - Diabetes Mellitus: Chronic Complications

CHAPTER 4 THYROID & PARATHYROID

□ 4.1 - Hypothyroidism: Overview & Hashimoto's Thyroiditis

□ 4.2 - Hypothyroidism: Other Causes
□ 4.3 - Hyperthyroidism: Overview & Graves' Disease
□ 4.4 - Thyroid Nodules & Cancer
□ 4.5 - Parathyroid Gland Disorders
□ 4.6 - Multiple Endocrine Neoplasia (MEN)
□

VIII. Reproductive & GU

CHAPTER 1 UTERINE & VULVOVAGINAL DISORDERS

□ 1.1 - Abnormal Uterine Bleeding (AUB) & Endometriosis

□ 1.2 - Cervical Neoplasia
□ 1.3 - Vulvar & Vaginal Lesions

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CHAPTER 2 REPRODUCTIVE HORMONES & OVARIAN DISORDERS

□ 2.1 - Reproductive Hormones Overview & Polycystic Ovary Syndrome (PCOS)

□ 2.2 - Amenorrhea
□ 2.3 - Ovarian Cysts & Epithelial Ovarian Cancer
□ 2.4 - Ovarian Neoplasms (Germ Cell & Sex Cord-Stromal Tumors)

CHAPTER 3 GESTATIONAL DISORDERS

□ 3.1 - Hydatidiform Mole & Choriocarcinoma

□ 3.2 - Gestational Disorders
□ 3.3 - Polyhydramnios & Oligohydramnios

CHAPTER 4 BREAST

□ 4.1 - Benign Breast Disorders

□ 4.2 - Breast Cancer

CHAPTER 5 MALE GU

□ 5.1 - Testicular Disorders & Cancer

□ 5.2 - Benign Prostatic Hyperplasia (BPH) & Prostate Cancer
□ 5.3 - Bladder Cancer & Penile Disorders

IX. Blood & Coagulation

CHAPTER 1 MICROCYTIC ANEMIAS

□ 1.1 - Microcytic Anemia: Overview & Thalassemias

□ 1.2 - Iron Deficiency Anemia & Anemia of Chronic Disease

CHAPTER 2 NORMOCYTIC & MACROCYTIC ANEMIAS

□ 2.1 - Extravascular Hemolysis: Overview & RBC Membrane Defects

□ 2.2 - Intravascular Hemolysis: Overiew & Paroxysmal Nocturnal Hemoglobinuria (PNH)
□ 2.3 - G6PD Deficiency & Autoimmune Hemolytic Anemia (AIHA)
□ 2.4 - Sickle Cell Disease
□ 2.5 - Megaloblastic Anemia: Folate Deficiency & Vitamin B12 Deficiency

CHAPTER 3 COAGULOPATHIES & PLATELET DISORDERS

□ 3.1 - Quantitative Platelet Disorders

□ 3.2 - Qualitative Platelet Disorders
□ 3.3 - Inherited Coagulation Defects
□ 3.4 - Acquired Coagulation Defects
□ 3.5 - Acquired & Inherited Thrombosis Syndromes

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X. Myeloid & Lymphoid

CHAPTER 1 MYELOID DISORDERS

□ 1.1 - Myeloproliferative Neoplasms & Myelodysplastic Syndromes

□ 1.2 - Acute Myeloid Leukemia (AML) & Chronic Myeloid Leukemia (CML)
□ 1.3 - Polycythemia

CHAPTER 2 LYMPHOID & PLASMA CELL DISORDERS

□ 2.1 - Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL), Hairy Cell
Leukemia & Adult T-cell Leukemia
□ 2.2 - Hodgkin Lymphoma
□ 2.3 - Non-Hodgkin Lymphoma
□ 2.4 - Plasma Cell Neoplasms

XI. Immunology
CHAPTER 1 AUTOIMMUNE & AMYLOIDOSIS

□ 1.1 - Autoimmune Disease: Overview & Systemic Lupus Erythematosus (SLE)

□ 1.2 - Sjogren's Syndrome, Systemic Sclerosis & Mixed Connective Tissue Disease
□ 1.3 - Polymyositis & Dermatomyositis
□ 1.4 - Amyloidosis

CHAPTER 2 IMMUNODEFICIENCY

□ 2.1 - B-Cell Disorders & DiGeorge Syndrome

□ 2.2 - Combined B & T-Cell Disorders
□ 2.3 - Complement System Disorders
□ 2.4 - Phagocytic Cell Disorders

XII. Musculoskeletal & Derm

CHAPTER 1 BONE

□ 1.1 - Osteoporosis & Paget Disease of Bone

□ 1.2 - Osteomalacia & Rickets
□ 1.3 - Benign Bone Tumors
□ 1.4 - Malignant Bone Tumors
□ 1.5 - Congenital Bone Disorders: Osteogenesis Imperfecta, Achondroplasia & Osteopetrosis

CHAPTER 2 JOINT

□ 2.1 - Osteoarthritis

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□ 2.2 - Rheumatoid Arthritis

□ 2.3 - Gout & Pseudogout

CHAPTER 3 MUSCLE

□ 3.1 - Muscular Dystrophies

□ 3.2 - Myasthenia Gravis & Lambert-Eaton Myasthenic Syndrome

CHAPTER 4 DERM

□ 4.1 - Actinic Keratosis, Squamous Cell Carcinoma & Basal Cell Carcinoma
□ 4.2 - Malignant Melanoma

XIII. Neuro
CHAPTER 1 CEREBROVASCULAR

□ 1.1 - Epidural Hematoma, Subdural Hematoma, & Subarachnoid Hemorrhage

□ 1.2 - Ischemic & Hemorrhagic Stroke

CHAPTER 2 INTRACRANIAL HYPERTENSION AND TUMORS

□ 2.1 - Intracranial Hypertension (ICH)

□ 2.2 - Hydrocephalus
□ 2.3 - Adult CNS Tumors
□ 2.4 - Pediatric CNS Tumors

CHAPTER 3 SPINAL CORD & PERIPHERAL NERVE

□ 3.1 - Spinal Muscular Atrophy, Amyotrophic Lateral Sclerosis (ALS) & Friedreich Ataxia
□ 3.2 - Multiple Sclerosis
□ 3.3 - Guillain-Barré & Charcot-Marie-Tooth

CHAPTER 4 CONGENITAL & NEUROCUTANEOUS

□ 4.1 - Neural Tube Defects, Holoprosencephaly, Chiari Malformation & Syringomyelia

□ 4.2 - Sturge-Weber & Tuberous Sclerosis
□ 4.3 – Neurofibromatosis

CHAPTER 5 NEURODEGENERATIVE

□ 5.1 - Alzheimer Disease & Dementia

□ 5.2 - Creutzfeldt-Jakob Disease, Parkinson's Disease & Huntington's Disease

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I. Metabolism
CHAPTER 1 CARBOHYDRATES

□ 1.1 - Glycolysis Part 1

□ 1.2 - Glycolysis Part 2
□ 1.3 - Regulation of PFK-1 and FBPase-1 by F-2,6-BP and During the Fed and Fasting State
□ 1.4 - Gluconeogenesis
□ 1.5 - Pyruvate Dehydrogenase Complex
□ 1.6 - Fates of Pyruvate
□ 1.7- Pyruvate Dehydrogenase Deficiency and Arsenic Poisoning
□ 1.8 - Hormonal Regulation of Glycogen by Insulin, Glucagon, and Epinephrine
□ 1.9 - TCA Cycle
□ 1.10 - Glycogen Synthesis (Glycogenesis) and Degradation (Glycogenolysis)
□ 1.11 - Malate-Aspartate and Glycerol-Phosphate Shuttles
□ 1.12 - Pentose Phosphate Pathway, G6PD Deficiency
□ 1.13 - Electron Transport Chain/Oxidative Phosphorylation
□ 1.14 - Metabolism and Disorders of Galactose
□ 1.15 - Metabolism and Disorders of Fructose and Sorbitol
□ 1.16 - Lactase Deficiency
□ 1.17 - Glycogen Storage Diseases
CHAPTER 2 AMINO ACIDS AND PROTEINS

□ 2.1 - Amino Acids (Overview)

□ 2.2 - Amino Acid Derivatives
□ 2.3 - Catecholamine Synthesis and Degradation
□ 2.4 - Inborn Errors of Amino Acid Metabolism (Overview), Phenylketonuria (PKU)
□ 2.6 - Disorders of Tyrosine Catabolism, Alkaptonuria
□ 2.7 - Branched-Chain Amino Acid Catabolism, Maple Syrup Urine Disease
□ 2.8 - Urea Cycle, Hyperammonemia, Ornithine Transcarbamylase Deficiency
□ 2.9 - The Cahill and Cori Cycles
□ 2.10 - Organic Acidemias
□ 2.11 - Homocystinuria
CHAPTER 3 LIPIDS

□ 3.1 - Triglyceride Catabolism, Beta Oxidation of Even-Chain Fatty Acids

□ 3.2 - Beta Oxidation of Odd-Chain Fatty Acids (VOMIT Pathway)
□ 3.3 - Ketone Bodies
□ 3.4 - Fatty Acid Synthesis

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 SKETCHY BIOCHEM

CHAPTER 4 ALCOHOL METABOLISM

□ 4.1 - Alcohol Metabolism

II. Cell Biology

CHAPTER 1 PARTS OF CELL
□ 1.1 - Collagen (Overview and Synthesis)
CHAPTER 2 LYSOSOMAL STORAGE DISEASES
□ 2.1 - Sphingolipidoses Part 1: Tay-Sachs Disease, Niemann-Pick Disease
□ 2.2 - Sphingolipidoses Part 2: Gaucher Disease, Metachromatic Leukodystrophy, Krabbe
Disease
□ 2.3 - Sphingolipidoses Part 3: Fabry Disease
□ 2.4 - Mucopolysaccharidoses: Hurler Syndrome, Hunter Syndrome

III. Molecular Biology

CHAPTER 1 DNA
□ 1.1 - Chromatin Structure
□ 1.2 - Purine (De-Novo) and Pyrimidine Synthesis
□ 1.3 - Purine Salvage Pathway
□ 1.5 - Purine Salvage Deficiencies (Adenosine Deaminase Deficiency, Lesch-Nyhan
Syndrome)
□ 1.6 - Lac Operon

IV. Vitamins & Minerals

CHAPTER 1 WATER SOLUBLE VITAMINS
□ 1.1 - Vitamin B1 (Thiamine)
□ 1.2 - Vitamin B2 (Riboflavin)
□ 1.3 - Vitamin B3 (Niacin)
□ 1.4 - Vitamin B5 (Pantothenic Acid)
□ 1.5 - Vitamin B6 (Pyridoxine)
□ 1.6 - Vitamin B7 (Biotin)
□ 1.7 - Vitamin B9 (Folate)
□ 1.8 - Vitamin B12 (Cobalamin)
□ 1.9 - Vitamin C

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CHAPTER 2 FAT SOLUBLE VITAMINS

□ 2.1 - Vitamin A
□ 2.2 - Vitamin D
□ 2.3 - Vitamin E
□ 2.4 - Vitamin K

V. Clinical Genetics
CHAPTER 1 POPULATION GENETICS
□ 1.1 - Hardy-Weinberg Population Genetics
CHAPTER 2 X-LINKED DOMINANT DISEASES
□ 2.1 - Rett Syndrome
CHAPTER 3 TRINUCLEOTIDE REPEAT DISEASES
□ 3.1 - Fragile-X Syndrome

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