51972020 Unites form Untitled form Antimicrobial agents 1. Which of the following B-lactam antibiotics can be safely used in patients with a history allergy to penicillins? Mark only one oval. A) r2treonam Cefepime ) Merepenem () Loracarbef 2. Adiabetic patient developed cellulitis due to Staph. aureus, which was found to be Methicillin-resistant on the antibiotic sensitivity testing. All of the following antibiotics will be appropriate, except? Mark only one oval. (_) Vancomycin CS, imipenem CO Linezolid () ceftaroline fosamil 3. Allthe following drug act on cell membrane except? Mark only one oval. © Poiymyxin 8 ) Amphotericin B SY) Bacitracin () nystatin hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt 1s.51972020 United form 4, Which of the following toxicities is unique to voriconazole among all azole antifungals? Mark only one oval. () Hepatic failure A visual disturbances CD Rash Ovorniting 5. Which of the following antibacterials can be used as a prokinetic agent in cases of diabetic-gastroparesis Mark only one oval. Paromomycin airithromycin ©) Vancomycin CS, Erythromycin 6. Which of the following anti-HIV drug has no action on HBV infection? Mark only one oval. ) Emtricitabine ) Lamivudine ~~) Tenofovir WA) abacavir hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt 21651972020 United form 7. The red-man syndrome occurs due to the infusion of Mark only one oval. () Rifampicin SH, vancomycin Amikacin Teicoplanin Which of the following agent is used in the prophylactic treatment of rheumatic heart disease Mark only one oval. ©) Amoxicillin wv Benzathine penicillin Ampicillin Crystalline Penicillin Drug of choice for Toxoplasmosis in pregnancy Mark only one oval. clindamycin A spiramycin (azithromycin (Gentamicin hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt ans51972020 United form 10. ivermectin is used for the treatment of: Mark only one oval, SA, Fiariasis OD ascariasis Teniasis ) Hookworm infestation 11. Which of the following anti TB drugs act as a “Sterilizing” agent Mark only one oval. na CA pyrazinamide () Rifampicin ) Ethambutol 12. _Allof the following drugs are used as a part of MDT for MBL, except? Mark only one oval. > Rifampin (©) apsone () elofazimine W; ethionamide hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt ans51972020 United form 13. _Allof the following drugs are used for the treatment of Kala-azar as per National Vector Borne Disease Control Programme in India, except? Mark only one oval. J Liposomal Amphotericin B () Miltefosine ws ‘Sodium stibogluconate > Paramomycin 14, _Allof the following antimicrobial agents act by binding to 30S subunit of the ribosome, except? Mark only one oval. Aminoglycosides Tetracyelines A erythromycin (—) Spectinomycin 15. Which of the following drug is used as a single-dose treatment of acute uncomplicated cystitis Mark only one oval. —_) Nitrofurantoin —) Levofloxacin Fosfomycin Methenamine hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt ens51972020 16, 17, 18, Unites form Which of the following Fluoroquinolones has the longest t1/2? Mark only one oval, —) Ciprofloxacin (©) Levofloxacin SY) moxifloxacin ) Lomefloxacin All of the following are the mechanisms of resistance to the B-lactam group of antibiotics except? Mark only one oval. ( brug inactivation by Bactamases c A Active drug efflux Altered PBP targets (—) Reduced diffusion through porin channels Which of the following side effects is most likely to occur in slow acetylators on treatment with INH for pulmonary tuberculosis? Mark only one oval. Peripheral neuropathy () Hepatotoxicity (—) Thrombocytopenia (C_) Nephrotoxicity hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt ens51872020 Unie form 19. Which of the following Antitubercular drug is associated with hypothyroidism? Mark only one oval, —) Rifampicin (_) Pyrazinamide Ethionamide ») Streptomycin 20. Antihelminthic contraindicated in a patient with the seizure disorder is Mark only one oval. vec » Albendazole SA, Piperazine —_) Pyrantel pamoate 21. Drug effective for the treatment of common gram-negative anaerobes is. Mark only one oval. Aztreonam W, voxyeyeline Veneomyein —) Tobramycin hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt 7651972020 22. 23, 24, Unites form A patient on antimicrobial therapy develops the following signs and symptoms that ultimately are found to be drug-induced: cough, dyspnea, and pulmonary infiltrate; neutropenia and bleeding tendencies; and paresthesias. What was the most likely cause of the aforementioned symptoms? Mark only one oval. WV) amoxicitin () Aaithromycin (C_) Ciprofloxacin na Which of the following Rifamycins is not used for mycobacterial infections Mark only one oval. —) Rifampin AF Rifaximin Rifabutin () Rifapentine Which antibacterial agent appears to be the safest to use in the pregnant patient? Mark only one oval. D> amikacin () aaithromycin (©) Ciprofloxacin S) erythromycin hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt ans51972020 United form 25, Mark only one oval, —_) Cotrimoxazole () Furazolidone —) Nalidixie acid SA, ceftriaxone 26. Which of the following acts by inhibiting cell wall synthesis? Mark only one oval. W) penicitiin (_) Tetracycline (_) Ciprofloxacin —_) Chloramphenicol 27. Which of the following is not a third-generation Cephalosporin? Mark only one oval. Cefotaxime —_) Cefoperazone —_) Cefixime Cefadroxil hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt All of the following drugs are C/| in patients with G-6-PD deficiency except? ons51972020 United form 28. The group of antibiotics which possess an additional anti-inflammatory & immunomodulatory activities is Mark only one oval. ) Tetracyclines (—_) Polypeptide antibiotics (—) Fluoroquinolones Macrolides 29. Allof the following drugs are useful in the treatment of Pseudomonas aeruginosa except? Mark only one oval. Cephalexin ) Piperacillin ceftazidime (©) Plazomicin 30. One of the following is not penicillinase susceptible? Mark only one oval. amoxicillin (C_) Penicillin & (_) Piperacillin SA, cloxacitiin hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt 101651972020 31 32, 33, ‘Unites form True about Aminoglycosides are all except? Mark only one oval, Are bacteriostatic (—) Distributed only extracellularly —) excreted unchanged in urine ) Teratogenic Agents that exhibit time-dependent killing include all of the following except? Mark only one oval. (> Penieittins (_) Cephalosporins SV) aminoglycosides © Vancomycin Drug of choice for the prophylaxis of diphtheria is: Mark only one oval. (C_) Tetracycline CM Penicillin —) Ciprofloxacin (CD Erythromyein hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt ans51972020 34, 35. 36, ‘Unites form Allof the following drugs are neuraminidase inhibitors, except? Mark only one oval, —_) oseltamivir ( Zanamivir Cidofovir ) Peramivir Entry Inhibitors useful in the treatment of HIV-1 include all except? Mark only one oval. —) Enfuvirtide () bbalizumab oA Rattegravir (CO Maraviroc A 65-year-old woman has returned from a vacation abroad suffering from traveller's diarrhoea, and her problem has not responded to conventional antidiarrheal drugs. A pathogenic Gram-negative bacillus is suspected. Which drug is most likely to be effective in the treatment of this patient? Mark only one oval. —) Ampicillin Ofloxacin > sulfadiazine (Trimethoprim hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt rans51972020 United form 37. if amphotericin B is administered, the patient should be premedicated with Mark only one oval, —_) Diphenhydramine (—) bbuprofen —) Meperidine CW Any or all of the above 38. Ina patient suffering from pseudomembranous colitis due to C difficile with established hypersensitivity to metronidazole, the most likely drug to be of clinical value is Mark only one oval. (©) amoxicillin —) Doxyeycline —) Levofloxacin A) vancomycin 39. If the 10-year-old girl recovers from the acute falciparum attack but a month later develops P vivax malaria, what drug or drugs should be given to eradicate schizonts and latent hypnozoites in the liver? Mark only one oval. —_) Artesunate (_) Dapsone A) Primaquine © auinine hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt 13651972020 40. 4 42. ‘Unites form Metronidazole is not effective in the treatment of Mark only one oval, —_) Amebiasis. (—) infections due to Bacteroides fragilis Trichomoniasis WV, Infections due to Pneumocystis jirovecii Candida is a major cause of nosocomial bloodstream infection. The opportunistic fungal infection in such patients could have been prevented by the administration of Mark only one oval. (_) Caspofungin —_) Flucytosine > nystatin Vericonazole Linezolid is best used for Mark only one oval. WF mesa — vrsa © Kpneumoniae Ecol hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt vans51972020 United form 43. Which of the following drug causes Pseudotumor cerebri? Mark only one oval, —_) Sparfloxacin Gs Tetracycline > Gentamicin ) Clofazimine 44, Adrug that can cause hypertrophic pyloric stenosis is: Mark only one oval. (_) Tetracycline —_) Erythromycin () ampicillin —) Rifampicin 45. Drug of choice in pneumonia caused by P jirovecii is: Mark only one oval. Penicillin Cotrimoxazole >) kenamyein © Levofloxacin ‘This content is neither cteated nor endorsed by Google hitps:docs. google. comiformsld/tZebRgi219CTITLe_s-KaSzk3o5PKENWatFI62sWevUlodt 1516