IMMUNOLOGY AND IMMUNODIAGNOSTICS

1.The ability of an organism to resist infections by the pathogens is called___________

a) Infection
b) Hypersensitivity
c) Immunity
d) Allergy
2.Innate immunity present since birth and it has no memory.
a) True
b) False
3.Name the cytokines which released in response to virus infection?
a) Interferons
b) Monokines
c) Lymphokines
d) Interleukins
4.Name the first cell which recruited at the place of infection.
a) Nk cells
b) Basophils
c) Neutrophils
d) Macrophages
5. The thymus independent type 1 antigens are
a)Polysaccharide of bacterial origin
b)Bacterial nucleic acids
c)Small proteins of bacterial origin
d)Viral nucleic acids
6. Cell mediated immunity is carried out by………… while humoral immunity is mainly
carried out by……………….
a) B cells/T cells
b) Epitopes/Antigens
c) T cells/B cells
d)Antibodies/Antigens
7. B Cells are activated by
a) Complement
b) Antibody
c) Memory cells
d) Antigen
8. B cells mature in the………. while T cells mature in the
a) Thymus/bone marrow and gut associated lymphoid tissue (GALT)
 b) Spleen/bone marrow and GALT
c)Bone marrow and GALT/Thymus
d) Liver/Kidneys
9. Which of the following immune cells/molecules are most effective at destroying intracellular
pathogens?
a) T helper cells
b) B cells
c)Antibodies
d)T cytolytic cells
10. The ability of the immune system to recognize self-antigens versus nonself antigen is an
example of:
a)Specific immunity
b) Tolerance
c)Cell mediated immunity
d) Antigenic immunity
11. Which of the following is not involved in first line defence?

a)Mucus membranes
b)Saliva
c)Tears
d)Antibodies
12. Natural killer cells are found in all of the following except:
a)Blood
b)Spleen
c)Lymph nodes
d)Red bone marrow
13. Largest 'lymphoid' organ in body is called as:
a)Thymus
b)Spleen
c)Liver
d)Tonsils
14. Which of the following is NOT a secondary lymphoid organ
a)Thymus
b)Spleen
c)Mesenteric lymph node
d)Payer’s patch
15. T lymphocytes
 a)Can ingest pathogens and kill them
b)Can recirculate through the blood and lymphoid organs
c)Are short lived
d)Are educated in the bone marrow
16. Humoral immunity is mediated by
a)B cells
b)Macrophages
c)Both (a) & (b)
d)Phagocytes
17. The function of memory B cell is
a)Antibody production
b)Immunologic memory
c)Regulated antibody production
d)None of these
18. The characteristics of adaptive immunity include
a)Specificity
b)Immunologic memory
c)Discrimination of self from non-self molecules
d)All of these
19. Which of the following statements are true regarding adaptive immunity
a)Prior exposure to antigen is essential
b)Prior exposure to antigen is not essential
c)It is a non-specific defence mechanism
d)Macrophages are the major cells involved
20.Injection of anti-venom against snake bite is an example of
a)Active immunity
b)Passive immunity
c)Non-specific immunity
d)Phagocytic immunity