ENGLISH TASK

“THE RETURN OF THALIDOMIDE”

Lecture: Ms. Sofia F. Rachmani M.Pd.

Group 7B:
1. Fani Nurhaliza (P3.73.20.2.20.068)
2. Hanifah Dhea Adhitya (P3.73.20.2.20.073)
3. Sherina Octaviani (P3.73.20.2.20.097)
4. Shynta Ayu Setyaningtyas (P3.73.20.2.20.098)

NURSE PROFESSIONAL STUDY PROGRAM

NURSING MAJOR

HEALTH POLYTECHNIC MINISTRY OF HEALTH JAKARTA III

2021
 “The Return Of Thalidomide”

In 1961 an Australian doctor, William McBride, noticed a sudden increase in the number of
babies being born with one or more limbs missing. He realized that all their mothers had taken the same
drug during pregnancy, and he alerted the medical word. The drug, Thalidomide, had been used since the
late 50s to combat nausea during pregnancy. When its catastrophic died in their first year – it was
withdrawn from use.
The drug had been believed café, 3c it had been thoroughly tested on animals. Test had shown
that rats could be given massive doses without any ill-effects. Today’s strict rules for drug-testing owe a
great deal to Thalidomide.
The drug remained out of use until 1964, when Dr Jacob Sheskin found some old boxes of it in
his French clinic, and decided to try it as a sedative to relieve the suffering of a patient with leprosy
disappeared. Since then, the drug has continuously been trialled as a treatment for a wide range of
condition.
The powerful anti-inflammatory properties of the drug make it effective at treating arthritis.
AIDS, multiple sclerosis and over 100 other conditions, including many autoimmune disorders. It is also
believed to restrict the growth of blood vessels in cancerous tumoure. Garry Edlin, a patient whose rare
form of cancer, mantle cell lymphoma, has been successfully treated by Thalidomide at Demiford
Hospital in the UK, said ‘Within ten days the huge lumps had gone – it’s like a miracle cure”
Although Thalidomide is known to be effective, we do not fully understand how it works. For
this reason, and because of the memories of its devastating introduction, it will take some time before
Thalidomide is widely accepted as a treatment.

1. Read the article and decide if the sentences are true (T) or false (F)
1. One of the side effects of Thalidomide was nausea (True)
2. 60% of mothers who took Thalidomide had normal children (False)
3. The tests carried out on Thalidomide were not strict enough (False)
4. Thalidomide can cure leprosy (True)
5. Thalidomide can damage the autoimmune system (True)
6. We still don’t know exactly how Thalidomide works (True)

2. Add these sentences to the end of the paragraphs (A-E) where they fit best
1. It has been so successful in many cases, that it is seen by some as a ‘wonder drug’ (E)
2. At least now this drug, which caused such tragedy when introduced, can now offer
hope to sufferers of conditions that are otherwise incurable (A)
3. Investigations began immediately into what had gone wrong (C)
4. However, Garry does suffer from side effects of the drug such as muscle pain, and
numbness in the hands and feet (D)
5. Drugs must now undergo through testing on human subjects before being made
available for general use (B)
 Summary

“The Return Of Thalidomide”

In 1961 an Australian doctor, William McBride, noticed a sudden increase in the number of
babies being born with one or more limbs missing. He realized that all their mothers had taken the same
drug during pregnancy, and he alerted the medical word. Test had shown that rats could be given
massive doses without any ill-effects. Today’s strict rules for drug-testing owe a great deal to
Thalidomide.

The drug remained out of use until 1964, when Dr Jacob Sheskin found some old boxes of it in
his French clinic, and decided to try it as a sedative to relieve the suffering of a patient with leprosy
disappeared. AIDS, multiple sclerosis and over 100 other conditions, including many autoimmune
disorders. It is also believed to restrict the growth of blood vessels in cancerous tumoure. Garry Edlin, a
patient whose rare form of cancer, mantle cell lymphoma, has been successfully treated by Thalidomide
at Demiford Hospital in the UK, said ‘Within ten days the huge lumps had gone – it’s like a miracle
cure"

In Indonesian

Pada tahun 1961 seorang dokter Australia, William McBride, melihat peningkatan mendadak dalam
jumlah bayi yang lahir dengan satu atau lebih anggota badan yang hilang. Dia menyadari bahwa semua
ibu mereka telah menggunakan obat yang sama selama kehamilan, dan dia mengingatkan kata medis.
Tes telah menunjukkan bahwa tikus dapat diberikan dosis besar tanpa efek buruk. Aturan ketat hari ini
untuk pengujian obat berutang banyak pada Thalidomide.
Obat itu tetap tidak digunakan sampai tahun 1964, ketika Dr Jacob Sheskin menemukan
beberapa kotak tua di klinik Prancisnya, dan memutuskan untuk mencobanya sebagai obat penenang
untuk meringankan penderitaan pasien kusta yang hilang. AIDS, multiple sclerosis dan lebih dari 100
kondisi lain, termasuk banyak gangguan autoimun. Hal ini juga diyakini untuk membatasi pertumbuhan
pembuluh darah pada tumor kanker. Garry Edlin, seorang pasien yang kankernya langka, limfoma sel
mantel, telah berhasil diobati oleh Thalidomide di Rumah Sakit Demiford di Inggris, mengatakan
'Dalam sepuluh hari benjolan besar telah hilang - ini seperti obat ajaib"